Protective roles of ascorbic acid in oxidative stress induced by depletion of superoxide dismutase in vertebrate cells

Free Radical Research

Volumn 47, Issue 1, 2013, Pages 1-7

  Tamari, Yuki ^a   Nawata, Hisakatsu ^a   Inoue, Eri ^b   Yoshimura, Akari ^c   Yoshii, Hanako ^a   Kashino, Genro ^a,d   Seki, Masayuki ^b   Enomoto, Takemi ^c   Watanabe, Masami ^a   Tano, Keizo ^a  

^a KYOTO UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c MUSASHINO UNIVERSITY   (Japan)

^d OITA UNIVERSITY   (Japan)

Author keywords

Antioxidant; Conditional knockout cell; DT40; SOD1; SOD2

Indexed keywords

ACETYLCYSTEINE; ASCORBIC ACID; ASCORBIC ACID PHOSPHATE ESTER MAGNESIUM; COPPER ZINC SUPEROXIDE DISMUTASE; ESTER; MANGANESE SUPEROXIDE DISMUTASE; MERCAPTOETHANOL; SUPEROXIDE DISMUTASE; TIRON; TROLOX C; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL GROWTH; CELL PROTECTION; CONTROLLED STUDY; CYTOPLASM; DRUG EFFECT; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; VERTEBRATE;

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; CHICKENS; GENE KNOCKOUT TECHNIQUES; HUMANS; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; VERTEBRATES;

VERTEBRATA;

EID: 84870831033     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715762.2012.734916     Document Type: Article

References (47)

1. Go YM, Jones DP. Cysteine/cystine redox signaling in cardiovascular disease. Free Radic Biol Med 2011; 50: 495-509.
2. Lassegue B, Griendling KK. NADPH oxidases: functions and pathologies in the vasculature. Arterioscler Thromb Vasc Biol 2010; 30: 653-661.
3. Ushio-Fukai M. Compartmentalization of redox signaling through NADPH oxidase-derived ROS. Antioxid Redox Signal 2009; 11: 1289-1299.
4. Woo HA, Yim SH, Shin DH, Kang DH, Yu DY, Rhee SG. Inactivation of peroxiredoxin I by phosphorylation allows localized H 2 O 2 accumulation for cell signaling. Cell 2010; 140: 517-528.
5. Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature 2000; 408: 239-247.
6. Marnett LJ, Plastaras JP. Endogenous DNA damage and mutation. Trends Genet 2001; 117: 214-221.
7. Buettner GR. Superoxide dismutase in redox biology: the roles of superoxide and hydrogen peroxide. Anticancer Agents Med Chem 2011; 11: 341-346.
8. Zelko IN, Mariani TJ, Folz RJ. Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression. Free Radic Biol Med 2002; 33: 337-349.
9. Crapo JD, Oury T, Rabouille C, Slot JW, Chang LY. Copper, zinc superoxide dismutase is primarily a cytosolic protein in human cells. Proc Natl Acad Sci USA 1992; 89: 10405-10409.
10. Okado-Matsumoto A, Fridovich I. Subcellular distribution of superoxide dismutases (SOD) in rat liver: Cu, Zn-SOD in mitochondria. J Biol Chem 2001; 276: 38388-38393.
11. Sturtz LA, Diekert K, Jensen LT, Lill R, Culotta VC. A fraction of yeast Cu, Zn-superoxide dismutase and its metallochaperone, CCS, localize to the intermembrane space of mitochondria. A physiological role for SOD1 in guarding against mitochondrial oxidative damage. J Biol Chem 2001; 276: 38084-38089.
12. Chang LY, Slot JW, Geuze HJ, Crapo JD. Molecular immunocytochemistry of the CuZn superoxide dismutase in rat hepatocytes. J Cell Biol 1988; 107: 2169-2179.
13. Fridovich I, Freeman B. Antioxidant defenses in the lung. Annu Rev Physiol 1986; 48: 693-702.
14. Weisiger RA, Fridovich I. Superoxide dismutase. Organelle specificity. J Biol Chem 1973; 248: 3582-3592.
15. Marklund SL, Holme E, Hellner L. Superoxide dismutase in extracellular fluids. Clin Chim Acta 1982; 126: 41-51.
16. Qin Z, Gongora MC, Ozumi K, Itoh S, Akram K, Ushio-Fukai M, et al. Role of Menkes ATPase in angiotensin II-induced hypertension: a key modulator for extracellular superoxide dismutase function. Hypertension 2008; 52: 811-812.
17. Kalmar B, Novoselov S, Gray A, Cheetham ME, Margulis B, Greensmith L. Late stage treatment with arimoclomol delays disease progression and prevents protein aggregation in the SOD1 mouse model of ALS. J Neurochem 2008; 107: 339-350.
18. Joseph A, Li Y, Koo HC, Davis JM, Pollack S, Kazzaz JA. Superoxide dismutase attenuates hyperoxia-induced interleukin-8 induction via AP-1. Free Radic Biol Med 2008; 45: 1143-1149.
19. Pawlak K, Domaniewski T, Mysliwiec M, Pawlak D. The kynurenines are associated with oxidative stress, inflammation and the prevalence of cardiovascular disease in patients with end-stage renal disease. Atherosclerosis 2008; 204: 309-314.
20. Kaewpila S, Venkataraman S, Buettner GR, Oberley LW. Manganese superoxide dismutase modulates hypoxiainducible factor-1 alpha induction via superoxide. Cancer Res 2008; 68: 2781-2788.
21. Oberley LW. Anticancer therapy by overexpression of superoxide dismutase. Antioxid Redox Signal 2001; 3: 461-472.
22. Traber MG, Stevens JF. Vitamin C and E: beneficial effects from mechanistic perspective. Free Radic Biol Med 2011; 51: 1000-1013.
23. Frei B, England L, Ames BN. Ascorbate is an outstanding antioxidant in human blood plasma. Proc Natl Acad Sci USA 1989; 86: 6377-6381.
24. Frei B, Stocker R, England L, Ames BN. Ascorbate: the most effective antioxidant in human blood plasma. Adv Exp Med Biol 1990; 264: 155-163.
25. Heaney ML, Gardner JR, Karasavvas N, Golde DW, Schneinberg DA, Smith EA, O ' Connor OA. Vitamin C antagonizes the cytotoxic effects of antineoplastic drugs. Cancer Res 2008; 68: 8031-8038.
26. Verrax J, Calderon PB. The controversial place of vitamin C in cancer treatment. Biochem Pharmacol 2008; 76: 1644-1652.
27. Carr A, Frei B. Does vitamin C act as a pro-oxidant under physiological conditions? FASEB J 1999; 13: 1007-1024.
28. Hara S, Mizukami H, Kuriwa F, Endo T. Hydroxyl radical generation dependent on extracellular ascorbate in rat striatum, as determined by microdialysis. Toxicology 2009; 258: 10-16.
29. Kang MJ, Lee SS, Koh HC. Prooxidant properties of ascorbic acid in the nigrostriatal dopaminergic system of C57BL/6 mice. Toxicology 2012; 294: 1-8.
30. Schneider M, Diemer K, Engelhart K, Zankl H, Trommer WE, Biesalski HK. Protective effects of vitamin C and E on the number of micronuclei in lymphocytes in smokers and their role in ascorbate free radical formation. Free Radic Res 2001; 34: 209-219.
31. Brennan LA, Morris GM, Wasson GR, Hannigan BM, Barnett YA. The effect of vitamin C or vitamin E supplementation on basal and H 2 O 2-induced DNA damage in human lymphocytes. Br J Nutr 2000; 84: 195-202.
32. Kashino G, Kodama S, Nakayama Y, Suzuki K, Fukase K, Goto M, Watanabe M. Relief of oxidative stress by ascorbic acid delays cellular senescence of normal human and Werner syndrome fibroblast cells. Free Radic Biol Med 2003; 35: 438-443.
33. Takada S, Inoue E, Tano K, Yoshii H, Abe T, Yoshimura A, et al. Generation and characterization of cells that can be conditionally depleted of mitochondrial SOD2. Biochem Biophys Res Commun 2009; 379: 233-238.
34. Inoue E, Tano K, Yoshii H, Nakamura J, Tada S, Watanabe M, et al. SOD1 is essential for the viability of DT40 cells and nuclear SOD1 functions as a guardian of genomic DNA. J Nucleic Acid 2010; 2010: 795946 doi:10. 4061/2010/795946.
35. Maeda H, Yamamoto K, Kohno I, Itoh N, Hafsi L, Nakagawa S, et al. Design of a practical fluorescent probe for superoxide based on protection-deprotection chemistry of fluoresceins with benzenesulfonyl protecting groups. Chemistry 2007; 13: 1946-1954.
36. Robinson KM, Janes MS, Pehar M, Monette JS, Ross MF, Hagen TM, et al. Selective fluorescent imaging of superoxide in vivo using ethidium-based probes. Proc Natl Acad Sci USA 2006; 103: 15038-15043.
37. Yohii H, Watanabe M. Intervention of oxygen-control ability to radiation sensitivity, cell aging and cell transformation. J Radiat Res 2009; 50: 127-137.
38. Halliwell B, Gutteridge JMC. Ascorbic acid (vitamin C). In: Halliwell B, Gutteridge JMC (eds. ). Free Radicals in Biology and Medicine, 4th ed. New York: Oxford University Press; 2007. pp. 160-166.
39. Harada T, Kashino G, Suzuki K, Matsuda N, Kodama S, Watanabe M. Different involvement of radical species in irradiated and bystander cells. Int J Radiat Biol 2008; 84: 809-814.
40. Koyama S, Kodama S, Suzuki K, Matsumoto T, Miyazaki T, Watanabe M. Radiation-induced long-lived radicals which cause mutation and transformation. Mutat Res 1998; 421: 45-54.
41. Fernandez D, Perl A. Metabolic control of T cell activation and death in SLE. Autoimmun Rev 2009; 8: 184-189.
42. Nordberg J, Arn ?r ESJ. Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radic Biol Med 2001; 31: 1287-1312.
43. Missirlis F, Hu J, Kirby K, Hilliker AJ, Rouault TA, Phillips JP. Compartment-specific protection of iron-sulfur proteins by superoxide dismutase. J Biol Chem 2003; 278: 47365-47369.
44. Li J-M, Shah AM. Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology. Am J Physiol Regul Integr Comp Physiol. 2004; 287: R1014-R1030.
45. Beal MF. Aging, energy, and oxidative stress in neurodegenerative diseases. Ann Neurol 1995; 38: 357-366.
46. Hinerfeld D, Traini MD, Weinberger RP, Cochran B, Doctrow SR, Harry J, Melov S. Endogenous mitochondrial oxidative stress: neurodegeneration, proteomic analysis, specific respiratory chain defects, and efficacious antioxidant therapy in superoxide dismutase 2 null mice. J Neurochem 2004; 88: 657-667.
47. Tao R, Coleman ML, Pennington JD, Ozen O, Park S-H, Jiang H, et al. Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress. Mol Cell 2010; 40: 893-904.