Treatment of post-traumatic cognitive impairments

Current Treatment Options in Neurology

Volumn 14, Issue 5, 2012, Pages 493-508

  Wortzel, Hal S ^a,b   Arciniegas, David B ^b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Cognitive disorders; Drug therapy; Post traumatic cognitive impairments; Rehabilitation; Traumatic brain injury; Treatment

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; AMANTADINE; ANESTHETIC AGENT; ANTIHYPERTENSIVE AGENT; BENZODIAZEPINE DERIVATIVE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BROMOCRIPTINE; CARBAMAZEPINE; CHOLINERGIC RECEPTOR BLOCKING AGENT; CITICOLINE; DEXAMETHASONE; DONEPEZIL; DOPAMINE RECEPTOR BLOCKING AGENT; HYDROCHLOROTHIAZIDE PLUS TRIAMTERENE; KETOCONAZOLE; MEMANTINE; METHYLPHENIDATE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PHENOBARBITAL; PHENYLBUTAZONE; PHENYTOIN; PRIMIDONE; PSYCHOSTIMULANT AGENT; QUINIDINE; RIFAMPICIN; RIVASTIGMINE; TRICYCLIC ANTIDEPRESSANT AGENT; UNINDEXED DRUG; VALPROIC ACID; WARFARIN;

ABDOMINAL CRAMP; ABNORMAL DREAMING; ANOREXIA; ANXIETY; ARTICLE; ASTHENIA; ATTENTION; BLOOD PRESSURE; BLURRED VISION; COGNITIVE DEFECT; COGNITIVE REHABILITATION; COGNITIVE THERAPY; COMMUNICATION SKILL; CONFUSION; CONSTIPATION; DECREASED APPETITE; DEPRESSION; DIARRHEA; DIFFERENTIAL DIAGNOSIS; DIZZINESS; DOSE RESPONSE; DROWSINESS; DRUG ANTAGONISM; DRUG DOSE INCREASE; DRUG INDUCED HEADACHE; DRUG MECHANISM; DRUG POTENTIATION; DYSPHORIA; EXECUTIVE FUNCTION; FAINTNESS; FATIGUE; HALLUCINATION; HEART RATE; HUMAN; INSOMNIA; IRRITABILITY; LOW DRUG DOSE; MEMORY; MORNING DOSAGE; MUSCLE CRAMP; NAUSEA; NEUROPSYCHOLOGICAL TEST; ORTHOSTATIC HYPOTENSION; PAIN; PATIENT COUNSELING; PATIENT EDUCATION; POSTTRAUMATIC COGNITIVE IMPAIRMENT; PSYCHOSIS; PSYCHOTHERAPY; SEIZURE; SIDE EFFECT; SWEATING; THORAX PAIN; TRAUMATIC BRAIN INJURY; VOMITING;

EID: 84870828353     PISSN: 10928480     EISSN: 15343138     Source Type: Journal    
DOI: 10.1007/s11940-012-0193-6     Document Type: Article

References (88)

1. Langlois JA, Rutland-Brown W, Wald MM. The epidemiology and impact of traumatic brain injury: a brief overview. J Head Trauma Rehabil. 2006;21(5):375-8.
2. Rutland-Brown W, Langlois JA, Thomas KE, Xi YL. Incidence of traumatic brain injury in the United States, 2003. J Head Trauma Rehabil. 2006;21(6):544-8.
3. Kay T, Harrington DE, Adams RE, et al. Definition of mild traumatic brain injury: report from Mild Traumatic Brain Injury Committee of the Head Injury Interdisciplinary Special Interest Group of the American Congress of Rehabilitation Medicine. J Head Trauma Rehabil. 1993;8(3):86-7.
4. Marr A, Coronado VG. Central nervous system injury surveillance data submission standards -2002. Atlanta: National Center for Injury Control and Prevention; 2002.
5. Department of Veterans Affairs, Department of Defense. VA/DoD Clinical Practice Guideline for Management of Concussion/Mild Traumatic Brain Injury. J Rehabil Res Dev. 2009;46(6):CP1-68.
6. Menon DK, Schwab K, Wright DW, Maas AI. Position statement: definition of traumatic brain injury. Arch Phys Med Rehabil. 2010;91(11):1637-40.
7. Dikmen SS, Corrigan JD, Levin HS, Machamer J, Stiers W, Weisskopf MG. Cognitive outcome following traumatic brain injury. J Head Trauma Rehabil. 2009;24(6):430-8.
8. Millis SR, Rosenthal M, Novack TA, Sherer M, Nick TG, Kreutzer JS, et al. Long-term neuropsychological outcome after traumatic brain injury. J Head Trauma Rehabil. 2001;16(4):343-55.
9. Selassie AW, Zaloshnja E, Langlois JA, Miller T, Jones P, Steiner C. Incidence of long-term disability following traumatic brain injury hospitalization, United States, 2003. J Head Trauma Rehabil. 2008;23 (2):123-31.
10. Zaloshnja E, Miller T, Langlois JA, Selassie AW. Prevalence of long-term disability from traumatic brain injury in the civilian population of the United States, 2005. J Head Trauma Rehabil. 2008;23 (6):394-400.
11. Anderson MI, Parmenter TR, Mok M. The relationship between neurobehavioural problems of severe traumatic brain injury (TBI), family functioning and the psychological well-being of the spouse/caregiver: path model analysis. Brain Inj. 2002;16(9):743-57.
12. Carroll LJ, Cassidy JD, Peloso PM, Borg J, von Holst H, Holm L et al. Prognosis for mild traumatic brain injury: results of the WHO Collaborating Centre Task Force on Mild Traumatic Brain Injury. J Rehabil Med. 2004;(43 Suppl):84-105.
13. McCrea M, Iverson GL, McAllister TW, Hammeke TA, Powell MR, Barr WB, et al. An integrated review of recovery after mild traumatic brain injury (MTBI): implications for clinical management. Clin Neuropsychol. 2009;23(8):1368-90.
14. Arciniegas DB, Anderson CA, Topkoff J, McAllister TW. Mild traumatic brain injury: a neuropsychiatric approach to diagnosis, evaluation, and treatment. Neuropsychiatr Dis Treat. 2005;1(4):311-27.
15. Hoge CW, Goldberg HM, Castro CA. Care of war veterans with mild traumatic brain injury-flawed perspectives. N Engl J Med. 2009;360(16):1588-91.
16. Williams DH, Levin HS, Eisenberg HM. Mild head injury classification. Neurosurgery. 1990;27(3):422-8.
17. van der Naalt J, Hew JM, van Zomeren AH, Sluiter WJ, Minderhoud JM. Computed tomography and magnetic resonance imaging in mild to moderate head injury: early and late imaging related to outcome. Ann Neurol. 1999;46(1):70-8.
18. Kashluba S, Hanks RA, Casey JE, Millis SR. Neuropsychologic and functional outcome after complicated mild traumatic brain injury. Arch Phys Med Rehabil. 2008;89(5):904-11.
19. Belanger HG, Vanderploeg RD. The neuropsychological impact of sports-related concussion: a metaanalysis. J Int Neuropsychol Soc. 2005;11(4):345-57.
20. Arciniegas DB, Topkoff JL. Applications of the P50 evoked response to the evaluation of cognitive impairments after traumatic brain injury. Phys Med Rehabil Clin North Am. 2004;15(1):177-203.
21. Cicerone KD, Dahlberg C, Kalmar K, Langenbahn DM, Malec JF, Bergquist TF, et al. Evidence-based cognitive rehabilitation: recommendations for clinical practice. Arch Phys Med Rehabil. 2000;81 (12):1596-615.
22. Cicerone KD, Dahlberg C, Malec JF, Langenbahn DM, Felicetti T, Kneipp S, et al. Evidence-based cognitive rehabilitation: updated review of the literature from 1998 through 2002. Arch Phys Med Rehabil. 2005;86(8):1681-92.
23. Cicerone KD, Langenbahn DM, Braden C, Malec JF, Kalmar K, Fraas M, et al. Evidence-based cognitive rehabilitation: updated review of the literature from 2003 through 2008. Arch Phys Med Rehabil. 2011;92 (4):519-30.
24. Rohling ML, Faust ME, Beverly B, Demakis G. Effectiveness of cognitive rehabilitation following acquired brain injury: a meta-analytic re-examination of Cicerone et al'.s (2000, 2005) systematic reviews. Neuropsychology. 2009;23(1):20-39.
25. Cappa SF, Benke T, Clarke S, Rossi B, Stemmer B, van Heugten CM. EFNS guidelines on cognitive rehabilitation: report of an EFNS task force. Eur J Neurol. 2003;10(1):11-23.
26. Cappa SF, Benke T, Clarke S, Rossi B, Stemmer B, van Heugten CM. EFNS guidelines on cognitive rehabilitation: report of an EFNS task force. Eur J Neurol. 2005;12(9):665-80.
27. Alban JP, Hopson MM, Ly V, Whyte J. Effect of methylphenidate on vital signs and adverse effects in adults with traumatic brain injury. Am J Phys Med Rehabil. 2004;83(2):131-7.
28. Whyte J, Hart T, Schuster K, Fleming M, Polansky M, Coslett HB. Effects of methylphenidate on attentional function after traumatic brain injury. A randomized, placebo-controlled trial. Am J Phys Med Rehabil. 1997;76(6):440-50.
29. Whyte J, Hart T, Vaccaro M, Grieb-Neff P, Risser A, Polansky M, et al. Effects of methylphenidate on attention deficits after traumatic brain injury: a multidimensional, randomized, controlled trial. Am J Phys Med Rehabil. 2004;83(6):401-20.
30. Whyte J, Vaccaro M, Grieb-Neff P, Hart T, Polansky M, Coslett HB. The effects of bromocriptine on attention deficits after traumatic brain injury: a placebo-controlled pilot study. Am J Phys Med Rehabil. 2008;87(2):85-99.
31. Willmott C, Ponsford J. Efficacy of methylphenidate in the rehabilitation of attention following traumatic brain injury: a randomised, crossover, double blind, placebo controlled inpatient trial. J Neurol Neurosurg Psychiatry. 2009;80(5):552-7.
32. Willmott C, Ponsford J, Olver J, Ponsford M. Safety of methylphenidate following traumatic brain injury: impact on vital signs and side-effects during inpatient rehabilitation. J Rehabil Med. 2009;41(7):585-7.
33. Zhang L, Plotkin RC, Wang G, Sandel ME, Lee S. Cholinergic augmentation with donepezil enhances recovery in short-term memory and sustained attention after traumatic brain injury. Arch Phys Med Rehabil. 2004;85(7):1050-5.
34. Silver JM, Koumaras B, Chen M, Mirski D, Potkin SG, Reyes P, et al. Effects of rivastigmine on cognitive function in patients with traumatic brain injury. Neurology. 2006;67(5):748-55.
35. Warden DL, Gordon B, McAllister TW, Silver JM, Barth JT, Bruns J, et al. Guidelines for the pharmacologic treatment of neurobehavioral sequelae of traumatic brain injury. J Neurotrauma. 2006;23 (10):1468-14501.
36. Arciniegas DB, Silver JM. Pharmacotherapy of posttraumatic cognitive impairments. Behav Neurol. 2006;17(1):25-42.
37. Silver JM, Koumaras B, Meng X, Potkin SG, Reyes PF, Harvey PD, et al. Long-term effects of rivastigmine capsules in patients with traumatic brain injury. Brain Inj. 2009;23(2):123-32.
38. Chew E, Zafonte RD. Pharmacological management of neurobehavioral disorders following traumatic brain injury-a state-of-the-art review. J Rehabil Res Dev. 2009;46(6):851-79.
39. Wheaton P, Mathias JL, Vink R. Impact of early pharmacological treatment on cognitive and behavioral outcome after traumatic brain injury in adults: a meta-analysis. J Clin Psychopharmacol. 2009;29(5):468-77.
40. Wheaton P, Mathias JL, Vink R. Impact of pharmacological treatments on cognitive and behavioral outcome in the postacute stages of adult traumatic brain injury: a meta-analysis. J Clin Psychopharmacol. 2011;31(6):745-57.
41. Silver JM, McAllister TW, Yudofsky SC. Textbook of traumatic brain injury. 2nd ed. Washington, DC: American Psychiatric Publishing, Inc; 2011.
42. Zasler ND, Katz DI, Zafonte RD. Brain injurymedicine: Principles and practice. New York: Demos; 2007.
43. Tiersky LA, Anselmi V, Johnston MV, Kurtyka J, Roosen E, Schwartz T, et al. A trial of neuropsychologic rehabilitation in mild-spectrum traumatic brain injury. Arch Physical Med Rehabil. 2005;86 (8):1565-74.
44. Sohlberg MM, McLaughlin KA, Pavese A, Heidrich A, Posner MI. Evaluation of attention process training and brain injury education in persons with acquired brain injury. J Clin Exp Neuropsychol. 2000;22 (5):656-76.
45. Serino A, Ciaramelli E, Santantonio AD, Malagu S, Servadei F, Ladavas E. A pilot study for rehabilitation of central executive deficits after traumatic brain injury. Brain Inj. 2007;21(1):11-9.
46. Bourgeois MS, Lenius K, Turkstra L, Camp C. The effects of cognitive teletherapy on reported everyday memory behaviours of persons with chronic traumatic brain injury. Brain Inj. 2007;21 (12):1245-57.
47. Pitel AL, Beaunieux H, Lebaron N, Joyeux F, Desgranges B, Eustache F. Two case studies in the application of errorless learning techniques in memory impaired patients with additional executive deficits. Brain Inj. 2006;20(10):1099-110.
48. Bornhofen C, McDonald S. Treating deficits in emotion perception following traumatic brain injury. Neuropsychol Rehabil. 2008;18(1):22-44.
49. Dahlberg CA, Cusick CP, Hawley LA, Newman JK, Morey CE, Harrison-Felix CL, et al. Treatment efficacy of social communication skills training after traumatic brain injury: a randomized treatment and deferred treatment controlled trial. Arch Phys Med Rehabil. 2007;88(12):1561-73.
50. McDonald S, Tate R, Togher L, Bornhofen C, Long E, Gertler P, et al. Social skills treatment for people with severe, chronic acquired brain injuries: a multicenter trial. Arch Phys Med Rehabil. 2008;89(9):1648-59.
51. Goverover Y, Johnston MV, Toglia J, Deluca J. Treatment to improve self-awareness in persons with acquired brain injury. Brain Inj. 2007;21(9):913-23.
52. Cheng SK, Man DW. Management of impaired selfawareness in persons with traumatic brain injury. Brain Inj. 2006;20(6):621-8.
53. Sohlberg MM, Sprunk H, Metzelaar K. Efficacy of an external cuing system in an individual with severe frontal lobe damage. Cognit Rehabil. 1988;6:36-41.
54. Evans JJ, Emslie H, Wilson BA. External cueing systems in the rehabilitation of executive impairments of action. J Int Neuropsychol Soc. 1998;4(4):399-408.
55. Fox RM, Martella RC, Marchand-Martella NE. The acquisition, maintenance and generalization of problem solving skills by closed head injured adults. Behav Ther. 1989;20:61-76.
56. Cicerone KD, Giacino JT. Remediation of executive function deficits after traumatic brain injury. Neurorehabilitation. 1992;2:12-22.
57. Hewitt J, Evans JJ, Dritschel B. Theory driven rehabilitation of executive functioning: improving planning skills in people with traumatic brain injury through the use of an autobiographical episodic memory cueing procedure. Neuropsychologia. 2006;44(8):1468-74.
58. Lipton SA. Pathologically-activated therapeutics for neuroprotection: mechanism of NMDA receptor block by memantine and S-nitrosylation. Curr Drug Targets. 2007;8(5):621-32.
59. Saniova B, Drobny M, Kneslova L, Minarik M. The outcome of patients with severe head injuries treated with amantadine sulphate. J Neural Transm. 2004;111(4):511-4.
60. Arciniegas DB, McAllister TW. Neurobehavioral management of traumatic brain injury in the critical care setting. Crit Care Clin. 2008;24(4):737-65.
61. Arciniegas DB. Cholinergic dysfunction and cognitive impairment after traumatic brain injury. Part 2: evidence from basic and clinical investigations. J Head Trauma Rehabil. 2011;26(4):319-23.
62. Meythaler JM, Brunner RC, Johnson A, Novack TA. Amantadine to improve neurorecovery in traumatic brain injury-associated diffuse axonal injury: a pilot double-blind randomized trial. J Head Trauma Rehabil. 2002;17(4):300-13.
63. Giacino JT, Whyte J, Bagiella E, Kalmar K, Childs N, Khademi A, et al. Placebo-controlled trial of amantadine for severe traumatic brain injury. N Engl J Med. 2012;366(9):819-26.
64. Bleiberg J, Garmoe W, Cederquist J, Reeves D, Lux W. Effects of Dexedrine on performance consistency following brain injury -a double-blind placebo crossover case-study. Neuropsy Neuropsy Beh. 1993;6(4):245-8.
65. Evans RW, Gualtieri CT, Patterson D. Treatment of chronic closed head injury with psychostimulant drugs: a controlled case study and an appropriate evaluation procedure. J Nerv Ment Dis. 1987;175 (2):106-10.
66. Lee H, Kim SW, Kim JM, Shin IS, Yang SJ, Yoon JS. Comparing effects of methylphenidate, sertraline and placebo on neuropsychiatric sequelae in patients with traumatic brain injury. Hum Psychopharmacol. 2005;20(2):97-104.
67. Wroblewski BA, Leary JM, Phelan AM, Whyte J, Manning K. Methylphenidate and seizure frequency in brain injured patients with seizure disorders. J Clin Psychiatry. 1992;53(3):86-9.
68. McDowell S, Whyte J, D'Esposito M. Differential effect of a dopaminergic agonist on prefrontal function in traumatic brain injury patients. Brain. 1998;121 (Pt 6):1155-64.
69. Eames P. The use of Sinemet and bromocriptine. Brain Inj. 1989;3(3):319-22.
70. Passler MA, Riggs RV. Positive outcomes in traumatic brain injury-vegetative state: patients treated with bromocriptine. Arch Phys Med Rehabil. 2001;82 (3):311-5.
71. Giacino JT, Trott CT. Rehabilitative management of patients with disorders of consciousness: grand rounds. J Head Trauma Rehabil. 2004;19(3):254-65.
72. Levin HS, Peters BH, Kalisky Z, High Jr WM, von Laufen A, Eisenberg HM, et al. Effects of oral physostigmine and lecithin on memory and attention in closed head-injured patients. Cent Nerv Syst Trauma. 1986;3(4):333-42.
73. Tenovuo O. Central acetylcholinesterase inhibitors in the treatment of chronic traumatic brain injury-clinical experience in 111 patients. Prog Neuropsychopharmacol Biol Psychiatry. 2005;29 (1):61-7.
74. Masanic CA, Bayley MT, VanReekum R, Simard M. Open-label study of donepezil in traumatic brain injury. Arch Phys Med Rehabil. 2001;82(7):896-901.
75. Tenovuo O, Alin J, Helenius H. A randomized controlled trial of rivastigmine for chronic sequels of traumatic brain injury-what it showed and taught? Brain Inj. 2009;23(6):548-58.
76. Secades JJ, Frontera G. CDP-choline: pharmacological and clinical review. Meth Find Exp Clin Pharm. 1995;17(Suppl B):1-54.
77. Dixon CE, Ma X, Marion DW. Effects of CDPcholine treatment on neurobehavioral deficits after TBI and on hippocampal and neocortical acetylcholine release. J Neurotrauma. 1997;14 (3):161-9.
78. Zafonte R, Friedewald WT, Lee SM, Levin B, Diaz-Arrastia R, Ansel B, et al. The citicoline brain injury treatment (COBRIT) trial: design and methods. J Neurotrauma. 2009;26(12):2207-16.
79. Levin HS. Treatment of postconcussional symptoms with CDP-choline. J Neurol Sci. 1991;103(Suppl): S39-42.
80. Calatayud Maldonado V, Calatayud Perez JB, Aso Escario J. Effects of CDP-choline on the recovery of patients with head injury. J Neurol Sci. 1991;103 Suppl:S15-8.
81. Marion DW. Evidenced-based guidelines for traumatic brain injuries. Prog Neurol Surg. 2006;19:171-96.
82. Dikmen SS, Temkin NR, Miller B, Machamer J, Winn HR. Neurobehavioral effects of phenytoin prophylaxis of posttraumatic seizures. JAMA. 1991;265 (10):1271-7.
83. Smith Jr KR, Goulding PM, Wilderman D, Goldfader PR, Holterman-Hommes P, Wei F. Neurobehavioral effects of phenytoin and carbamazepine in patients recovering from brain trauma: a comparative study. Arch Neurol. 1994;51(7):653-60.
84. Temkin NR, Dikmen SS, Anderson GD, Wilensky AJ, Holmes MD, Cohen W, et al. Valproate therapy for prevention of posttraumatic seizures: a randomized trial. J Neurosurg. 1999;91(4):593-600.
85. Larson EB, Zollman FS. The effect of sleep medications on cognitive recovery from traumatic brain injury. J Head Trauma Rehabil. 2010;25(1):61-7.
86. Bell KR, Hoffman JM, Temkin NR, Powell JM, Fraser RT, Esselman PC, et al. The effect of telephone counselling on reducing post-traumatic symptoms after mild traumatic brain injury: a randomised trial. J Neurology Neurosurg Psychiatry. 2008;79 (11):1275-81.
87. Paniak C, Toller-Lobe G, Durand A, Nagy J. A randomized trial of two treatments for mild traumatic brain injury. Brain Inj. 1998;12(12):1011-23.
88. Bell KR, Temkin NR, Esselman PC, Doctor JN, Bombardier CH, Fraser RT, et al. The effect of a scheduled telephone intervention on outcome after moderate to severe traumatic brain injury: a randomized trial. Arch Phys Med Rehabil. 2005;86 (5):851-6.