Detection of early neuron degeneration and accompanying glial responses in the visual pathway in a rat model of acute intraocular hypertension

Brain Research

Volumn 1303, Issue , 2009, Pages 131-143

  Zhang, ShaoDan ^a   Wang, HuaiZhou ^a   Lu, QingJun ^a   Qing, GuoPing ^a   Wang, NingLi ^a   Wang, YiDi ^a   Li, ShuNing ^a   Yang, DiYa ^a   Yan, FanCheng ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Acute intraocular hypertension; Degenerative disease; Glia and other non neuronal cells; Glial fibrillary acidic protein (GFAP); Glutamine synthetase (GS); Ischemia; Lateral geniculate nucleus (LGN); Neural plasticity; Neuronal death; Superior colliculus (SC); Transsynaptic degeneration; Visual system

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE AMMONIA LIGASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR EYE CHAMBER; APOPTOSIS; ARTICLE; ASTROCYTE; ATROPHY; CELL DENSITY; CONTROLLED STUDY; GLIA CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INTRAOCULAR HYPERTENSION; LATERAL GENICULATE BODY; MUELLER CELL; NERVE CELL DEGENERATION; NEUROPROTECTION; NICK END LABELING; NISSL STAINING; NONHUMAN; OPTIC TRACT; PRIORITY JOURNAL; RAT; RETINA; RETINA GANGLION CELL; SUPERIOR COLLICULUS; VISUAL SYSTEM;

ACUTE DISEASE; ANIMALS; APOPTOSIS; AXONS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; EARLY DIAGNOSIS; FEMALE; GENICULATE BODIES; GLAUCOMA; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIOSIS; GLUTAMATE-AMMONIA LIGASE; IN SITU NICK-END LABELING; NERVE DEGENERATION; NEUROGLIA; RATS; RATS, WISTAR; RETINA; RETINAL DEGENERATION; RETINAL GANGLION CELLS; SUPERIOR COLLICULI; SYNAPSES; VISUAL PATHWAYS;

ANIMALIA; RATTUS;

EID: 71849092500     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2009.09.029     Document Type: Article

References (67)

1. Agulhon C., Petravicz J., McMullen A.B., Sweger E.J., Minton S.K., Taves S.R., Casper K.B., Fiacco T.A., and McCarthy K.D. What is the role of astrocyte calcium in neurophysiology?. Neuron 59 (2008) 932-946
2. Allen N.J., and Barres B.A. Neuroscience: Glia-more than just brain glue. Nature 457 (2009) 675-677
3. Battisti W.P., Wang J., Bozek K., and Murray M. Macrophages, microglia, and astrocytes are rapidly activated after crush injury of the goldfish optic nerve: a light and electron microscopic analysis. J. Comp. Neurol. 354 (1995) 306-320
4. Bernardos R.L., Barthel L.K., Meyers J.R., and Raymond P.A. Late-stage neuronal progenitors in the retina are radial Müller glia that function as retinal stem cells. J. Neurosci. 27 (2007) 7028-7040
5. Binder D.K., and Steinhauser C. Functional changes in astroglial cells in epilepsy. Glia 54 (2006) 358-368
6. Bringmann A., Uckermann O., Pannicke T., Iandiev I., Reichenbach A., and Wiedemann P. Neuronal versus glial cell swelling in the ischaemic retina. Acta Ophthalmol. Scand. 83 (2005) 528-538
7. Bywood P.T., and Johnson S.M. Dendrite loss is a characteristic early indicator of toxin-induced neurodegeneration in rat midbrain slices. Exp. Neurol. 161 (2000) 306-316
8. Canady K.S., Olavarria J.F., and Rubel E.W. Reduced retinal activity increases GFAP immunoreactivity in rat lateral geniculate nucleus. Brain Res. 663 (1994) 206-214
9. Crawford M.L., Harwerth R.S., Smith III E.L., Shen F., and Carter-Dawson L. Glaucoma in primates: cytochrome oxidase reactivity in parvo- and magnocellular pathways. Invest. Ophthalmol. Vis. Sci. 41 (2000) 1791-1802
10. Crawford M.L., Harwerth R.S., Smith III E.L., Mills S., and Ewing B. Experimental glaucoma in primates: changes in cytochrome oxidase blobs in V1 cortex. Invest. Ophthalmol. Vis. Sci. 42 (2001) 358-364
11. D'Ambrosio R. The role of glial membrane ion channels in seizures and epileptogenesis. Pharmacol. Ther. 103 (2004) 95-108
12. De Keyser J., Mostert J.P., and Koch M.W. Dysfunctional astrocytes as key players in the pathogenesis of central nervous system disorders. J. Neurol. Sci. 267 (2008) 3-16
13. Derouiche A., and Rauen T. Coincidence of l-glutamate/l-aspartate transporter (GLAST) and glutamine synthetase (GS) immunoreactions in retinal glia: evidence for coupling of GLAST and GS in transmitter clearance. J. Neurosci. Res. 42 (1995) 131-143
14. Eysel U.T., and Wolfhard U. The effects of partial retinal lesions on activity and size of cells in the dorsal lateral geniculate nucleus. J. Comp. Neurol. 229 (1984) 301-309
15. Farahani R., Pina-Benabou M.H., Kyrozis A., Siddiq A., Barradas P.C., Chiu F.C., Cavalcante L.A., Lai J.C., Stanton P.K., and Rozental R. Alterations in metabolism and gap junction expression may determine the role of astrocytes as "good samaritans" or executioners. Glia 50 (2005) 351-361
16. Fischer A.J., and Reh T.A. Potential of Müller glia to become neurogenic retinal progenitor cells. Glia 43 (2003) 70-76
17. Gonzalez D., Satriotomo I., Miki T., Lee K.Y., Yokoyama T., Touge T., Matsumoto Y., Li H.P., Kuriyama S., and Takeuchi Y. Changes of parvalbumin immunoreactive neurons and GFAP immunoreactive astrocytes in the rat lateral geniculate nucleus following monocular enucleation. Neurosci. Lett. 395 (2006) 149-154
18. Gordon G.R., Mulligan S.J., and MacVicar B.A. Astrocyte control of the cerebrovasculature. Glia 55 (2007) 1214-1221
19. Goursaud S., Kozlova E.N., Maloteaux J.M., and Hermans E. Cultured astrocytes derived from corpus callosum or cortical grey matter show distinct glutamate handling properties. J. Neurochem. 108 (2009) 1442-1452
20. Gupta N., and Yücel Y.H. Brain changes in glaucoma. Eur. J. Ophthalmol. 13 Suppl. 3 (2003) S32-S35
21. Gupta N., and Yücel Y.H. What changes can we expect in the brain of glaucoma patients?. Surv. Ophthalmol. 52 Suppl. 2 (2007) S122-S126
22. Gupta N., Ang L.C., Noël de Tilly L., Bidaisee L., and Yücel Y.H. Human glaucoma and neural degeneration in intracranial optic nerve, lateral geniculate nucleus, and visual cortex. Br. J. Ophthalmol. 90 (2006) 674-678
23. Gupta N., Ly T., Zhang Q., Kaufman P.L., Weinreb R.N., and Yücel Y.H. Chronic ocular hypertension induces dendrite pathology in the lateral geniculate nucleus of the brain. Exp. Eye Res. 84 (2007) 176-184
24. Gupta N., Greenberg G., de Tilly L.N., Gray B., Polemidiotis M., and Yücel Y.H. Atrophy of the lateral geniculate nucleus in human glaucoma detected by magnetic resonance imaging. Br. J. Ophthalmol. 93 (2009) 56-60
25. Hajós F. Changes in glial fibrillary acidic protein (GFAP) immonureactivity reflect neuronal states. Neurochem. Res. 33 (2008) 1643-1650
26. Hofbauer A., and Dräger U.C. Depth segregation of retinal ganglion cells projecting to mouse superior colliculus. J. Comp. Neurol. 234 (1985) 465-474
27. Hu B., Yip H.K., and So K.F. Localization of p75 neurotrophin receptor in the retina of the adult SD rat: an immunocytochemical study at light and electron microscopic levels. Glia 24 (1998) 187-197
28. Iandiev I., Wurm A., Hollborn M., Wiedemann P., Grimm C., Remé C.E., Reichenbach A., Pannicke T., and Bringmann A. Müller cell response to blue light injury of the rat retina. Invest. Ophthalmol. Vis. Sci. 49 (2008) 3559-3567
29. Imamura K., Onoe H., Shimazawa M., Nozaki S., Wada Y., Kato K., Nakajima H., Mizuma H., Onoe K., Taniguchi T., Sasaoka M., Hara H., Tanaka S., Araie M., and Watanabe Y. Molecular imaging reveals unique degenerative changes in experimental glaucoma. NeuroReport 20 (2009) 139-144
30. Ito Y., Shimazawa M., Inokuchi Y., Fukumitsu H., Furukawa S., Araie M., and Hara H. Degenerative alterations in the visual pathway after NMDA-induced retinal damage in mice. Brain Res. 1212 (2008) 89-101
31. Ito Y., Shimazawa M., Chen Y.N., Tsuruma K., Yamashima T., Araie M., and Hara H. Morphological changes in the visual pathway induced by experimental glaucoma in Japanese monkeys. Exp. Eye Res. 89 (2009) 246-255
32. Jabs R., Seifert G., and Steinhäuser C. Astrocytic function and its alteration in the epileptic brain. Epilepsia 49 Suppl. 2 (2008) 3-12
33. Kanamori A., Nakamura M., Nakanishi Y., Yamada Y., and Negi A. Long-term glial reactivity in rat retinas ipsilateral and contralateral to experimental glaucoma. Exp. Eye Res. 81 (2005) 48-56
34. Kuchibhotla K.V., Lattarulo C.R., Hyman B.T., and Bacskai B.J. Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice. Science 323 (2009) 1211-1215
35. Lam D.Y., Kaufman P.L., Gabelt B.T., To E.C., and Matsubara J.A. Neurochemical correlates of cortical plasticity after unilateral elevated intraocular pressure in a primate model of glaucoma. Invest. Ophthalmol. Vis. Sci. 44 (2003) 2573-2581
36. Lebrun-Julien F., Morquette B., Douillette A., Saragovi H.U., and Di Polo A. Inhibition of p75(NTR) in glia potentiates TrkA-mediated survival of injured retinal ganglion cells. Mol. Cell. Neurosci. 40 (2009) 410-420
37. Lindqvist N., Peinado-Ramónn P., Vidal-Sanz M., and Hallböök F. GDNF, Ret, GFRalpha1 and 2 in the adult rat retino-tectal system after optic nerve transections. Exp. Neurol. 187 (2004) 487-499
38. Matute C., Melone M., Vallejo-Illarramendi A., and Conti F. Increased expression of the astrocytic glutamate transporter GLT-1 in the prefrontal cortex of schizophrenics. Glia 49 (2005) 451-455
39. Mauch D.H., Nägler K., Schumacher S., Göritz C., Müller E.C., Otto A., and Pfrieger F.W. CNS synaptogenesis promoted by glia-derived cholesterol. Science 294 (2001) 1354-1357
40. Mendes-de-Aguiar C.B., Alchini R., Decker H., Alvarez-Silva M., Tasca C.I., and Trentin A.G. Thyroid hormone increases astrocytic glutamate uptake and protects astrocytes and neurons against glutamate toxicity. J. Neurosci. Res. 86 (2008) 3117-3125
41. Metea M.R., and Newman E.A. Glial cells dilate and constrict blood vessels: a mechanism of neurovascular coupling. J. Neurosci. 26 (2006) 2862-2870
42. Mrak R.E., and Griffinbc W.S. The role of activated astrocytes and of the neurotrophic cytokine S100B in the pathogenesis of Alzheimer's disease. Neurobiol. Aging 22 (2001) 915-922
43. Newman E., and Reichenbach A. The Müller cell: a functional element of the retina. Trends Neurosci. 19 (1996) 307-312
44. Otori Y., Shimada S., Tanaka K., Ishimoto I., Tano Y., and Tohyama M. Marked increase in glutamate-aspartate transporter (GLAST/GluT-1) mRNA following transient retinal ischemia. Brain Res. Mol. Brain Res. 27 (1994) 310-314
45. Pfrieger F.W., and Barres B.A. Synaptic efficacy enhanced by glial cells in vitro. Science 77 (1997) 1684-1687
46. Quigley H.A., McKinnon S.J., Zack D.J., Pease M.E., Kerrigan-Baumrind L.A., Kerrigan D.F., and Mitchell R.S. Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats. Invest. Ophthalmol. Vis. Sci. 41 (2000) 3460-3466
47. Roth S., Shaikh A.R., Hennelly M.M., Li Q., Bindokas V., and Graham C.E. Mitogen-activated protein kinases and retinal ischemia. Invest. Ophthalmol. Vis. Sci. 44 (2003) 5383-5395
48. Sakamoto K., Yonoki Y., Kubota Y., Kuwagata M., Saito M., Nakahara T., and Ishii K. Inducible nitric oxide synthase inhibitors abolished histological protection by late ischemic preconditioning in rat retina. Exp. Eye Res. 82 (2006) 512-518
49. Sasaoka M., Nakamura K., Shimazawa M., Ito Y., Araie M., and Hara H. Changes in visual fields and lateral geniculate nucleus in monkey laser-induced high intraocular pressure model. Exp. Eye Res. 86 (2008) 770-782
50. Schummers J., Yu H., and Sur M. Tuned responses of astrocytes and their influence on hemodynamic signals in the visual cortex. Science 320 (2008) 1638-1643
51. Tanaka H., Ito Y., Nakamura S., Shimazawa M., and Hara H. Involvement of brain-derived neurotrophic factor in timedependent neurodegeneration in the murine superior colliculus after intravitreal injection of N-methyl-d-aspartate. Mol. Vis. 15 (2009) 662-669
52. Tezel G., Chauhan B.C., LeBlanc R.P., and Wax M.B. Immunohistochemical assessment of the glial mitogen-activated protein kinase activation in glaucoma. Invest. Ophthalmol. Vis. Sci. 44 (2003) 3025-3033
53. Tian G.F., Azmi H., Takano T., Xu Q., Peng W., Lin J., Oberheim N., Lou N., Wang X., Zielke H.R., Kang J., and Nedergaard M. An astrocytic basis of epilepsy. Nat. Med. 11 (2005) 973-981
54. Thummel R., Kassen S.C., Enright J.M., Nelson C.M., Montgomery J.E., and Hyde D.R. Characterization of Müller glia and neuronal progenitors during adult zebrafish retinal regeneration. Exp. Eye Res. 87 (2008) 433-444
55. Ullian E.M., Sapperstein S.K., Christopherson K.S., and Barres B.A. Control of synapse number by glia. Science 291 (2001) 657-661
56. Wang L., Cioffi G.A., Cull G., Dong J., and Fortune B. Immunohistologic evidence for retinal glial cell changes in human glaucoma. Invest. Ophthalmol. Vis. Sci. 43 (2002) 1088-1094
57. Weber A.J., and Harman C. Structure-function relations of parasol cells in the normal and glaucomatous primate retina. Investig. Ophthalmol. Vis. Sci. 46 (2005) 3197-3207
58. Weber A.J., Chen H., Hubbard W.C., and Kaufman P.L. Experimental glaucoma and cell size, density, and number in the primate lateral geniculate nucleus. Invest. Ophthalmol. Vis. Sci. 41 (2000) 1370-1379
59. Weinreb R.N., and Khaw P.T. Primary open-angle glaucoma. Lancet 363 (2004) 1711-1720
60. Woldemussie E., Wijono M., and Ruiz G. Müller cell response to laser-induced increase in intraocular pressure in rats. Glia 47 (2004) 109-119
61. Xu F., Wei Y., Lu Q., Zheng D., Zhang F., Gao E., and Wang N. Immunohistochemical localization of sortilin and p75(NTR) in normal and ischemic rat retina. Neurosci. Lett. 454 (2009) 81-85
62. Xue L.P., Lu J., Cao Q., Hu S., Ding P., and Ling E.A. Müller glial cells express nestin coupled with glial fibrillary acidic protein in experimentally induced glaucoma in the rat retina. Neuroscience 139 (2006) 723-732
63. Yücel Y.H., and Gupta N. Glaucoma of the brain: a disease model for the study of transsynaptic neural degeneration. Prog. Brain Res. 173 (2008) 465-478
64. Yücel Y.H., Zhang Q., Gupta N., Kaufman P.L., and Weinreb R.N. Loss of neurons in magnocellular and parvocellular layers of the lateral geniculate nucleus in glaucoma. Arch. Ophthalmol. 118 (2000) 378-384
65. Yücel Y.H., Zhang Q., Weinreb R.N., Kaufman P.L., and Gupta N. Atrophy of relay neurons in magno- and parvocellular layers in the lateral geniculate nucleus in experimental glaucoma. Invest. Ophthalmol. Vis. Sci. 42 (2001) 3216-3222
66. Yücel Y.H., Zhang Q., Weinreb R.N., Kaufman P.L., and Gupta N. Effects of retinal ganglion cell loss on magno-, parvo-, koniocellular pathways in the lateral geniculate nucleus and visual cortex in glaucoma. Prog. Retin. Eye Res. 22 (2003) 465-481
67. Zonta M., Angulo M.C., Gobbo S., Rosengarten B., Hossmann K.A., Pozzan T., and Carmignoto G. Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation. Nat. Neurosci. 6 (2003) 43-50