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1
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13744264090
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Designing the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
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Lippman, S.M., Goodman, P.J., Klein, E.A. et al. Designing the Selenium and Vitamin E Cancer Prevention Trial (SELECT). J. Natl. Cancer Inst. 97, 94-102 (2005).
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(2005)
J. Natl. Cancer Inst
, vol.97
, pp. 94-102
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Lippman, S.M.1
Goodman, P.J.2
Klein, E.A.3
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2
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58149383852
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Lippman, S.M., Klein, E.A., Goodman, P.J. et al. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA 301, 39-51 (2009). This study reported the results of the largest cancer trial involving selenium that found that supplementation with pure L-selenomethionine and vitamin E, separately or in combination, does not decrease the incidence of prostate cancer in healthy American men.
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Lippman, S.M., Klein, E.A., Goodman, P.J. et al. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA 301, 39-51 (2009). This study reported the results of the largest cancer trial involving selenium that found that supplementation with pure L-selenomethionine and vitamin E, separately or in combination, does not decrease the incidence of prostate cancer in healthy American men.
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3
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0027275148
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Blot, W.J., Li, J.Y., Taylor, P.R. et al. Nutrition intervention trials in Linxian, China: supplementation with specific vitamin/mineral combinations, cancer incidence, and disease-specific mortality in the general population. J. Natl. Cancer Inst. 85, 1483-1492 (1993). This is one of the first reports on the beneficial role of selenium in reducing human cancer incidence.
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Blot, W.J., Li, J.Y., Taylor, P.R. et al. Nutrition intervention trials in Linxian, China: supplementation with specific vitamin/mineral combinations, cancer incidence, and disease-specific mortality in the general population. J. Natl. Cancer Inst. 85, 1483-1492 (1993). This is one of the first reports on the beneficial role of selenium in reducing human cancer incidence.
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4
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0010607277
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The alpha-tocopherol, beta carotene cancer prevention study group. The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers
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The alpha-tocopherol, beta carotene cancer prevention study group. The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N. Engl. J. Med. 330, 1029-1035 (1994).
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(1994)
N. Engl. J. Med
, vol.330
, pp. 1029-1035
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5
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1642625262
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Clark, L.C., Combs, G.F. Jr., Turnbull, B.W. et al. Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin: a randomized controlled trial. JAMA 276, 1957-1963 (1996). This is the best known and cited study that reported the results of the cancer trial and showed that supplementation of the diet with 200 micrograms/day selenium in the form of selenized yeast reduces the incidence of human prostate, lung and colon cancers.
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Clark, L.C., Combs, G.F. Jr., Turnbull, B.W. et al. Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin: a randomized controlled trial. JAMA 276, 1957-1963 (1996). This is the best known and cited study that reported the results of the cancer trial and showed that supplementation of the diet with 200 micrograms/day selenium in the form of selenized yeast reduces the incidence of human prostate, lung and colon cancers.
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6
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0036317615
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Baseline characteristics and the effect of selenium supplementation on cancer incidence in a randomized clinical trial: A summary report on the Nutritional Prevention of Cancer Trial
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Duffield-Lillico, A.J., Reid, M.E., Turnbull, B.W., Combs, G.F., Jr., Slate, E.H., Fischbach, L.A., Marshall, J.R., and Clark, L.C. Baseline characteristics and the effect of selenium supplementation on cancer incidence in a randomized clinical trial: A summary report on the Nutritional Prevention of Cancer Trial. Can. Epidem. Biomark. Preven. 11, 630-639 (2002).
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(2002)
Can. Epidem. Biomark. Preven
, vol.11
, pp. 630-639
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Duffield-Lillico, A.J.1
Reid, M.E.2
Turnbull, B.W.3
Combs Jr., G.F.4
Slate, E.H.5
Fischbach, L.A.6
Marshall, J.R.7
Clark, L.C.8
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7
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0038244793
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Duffield-Lillico, A.J., Dalkin, B.L., Reid, M.E., Turnbull, B.W., Slate, E.H., Jacobs, E.T., Marshall, J.R., and Clark, L.C., for the Nutritional Prevention of Cancer Study Group Selenium supplementation, baseline plasma selenium status and incidence of prostate cancer: an analysis of the complete treatment period of the Nutritional Prevention of Cancer Trial. BJU Int. 91, 608-612 (2003). This study reported the reanalysis of the Clark et al. study (5) and found that selenium reduced the incidence of prostate cancer in men with low baseline selenium status.
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Duffield-Lillico, A.J., Dalkin, B.L., Reid, M.E., Turnbull, B.W., Slate, E.H., Jacobs, E.T., Marshall, J.R., and Clark, L.C., for the Nutritional Prevention of Cancer Study Group Selenium supplementation, baseline plasma selenium status and incidence of prostate cancer: an analysis of the complete treatment period of the Nutritional Prevention of Cancer Trial. BJU Int. 91, 608-612 (2003). This study reported the reanalysis of the Clark et al. study (5) and found that selenium reduced the incidence of prostate cancer in men with low baseline selenium status.
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8
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0032542759
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Prostate cancer and supplementation with alpha-tocopherol and beta-carotene: Incidence and mortality in a controlled trial
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Heinonen, O.P., Albanes, D., Virtamo, J. et al. Prostate cancer and supplementation with alpha-tocopherol and beta-carotene: incidence and mortality in a controlled trial. J. Natl. Cancer Inst. 90, 440-446 (1998).
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(1998)
J. Natl. Cancer Inst
, vol.90
, pp. 440-446
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Heinonen, O.P.1
Albanes, D.2
Virtamo, J.3
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9
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0345310068
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Chemopreventive agents: Selenium
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Combs, G.F, Jr. and Gray, W.P. Chemopreventive agents: selenium. Pharmacol. Ther. 79, 179-192 (1998).
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(1998)
Pharmacol. Ther
, vol.79
, pp. 179-192
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Combs Jr., G.F.1
Gray, W.P.2
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10
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0031794470
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Lessons from basic research in selenium and cancer prevention
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Ip, C. Lessons from basic research in selenium and cancer prevention. J. Nutr. 128, 1845-1854 (1998).
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(1998)
J. Nutr
, vol.128
, pp. 1845-1854
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Ip, C.1
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11
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0033947985
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Chemical speciation influences comparative activity of selenium-enriched garlic and yeast in mammary cancer prevention
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Ip, C., Birringer, M., Block, E., Kotrebai, M., Tyson, J.F., Uden, P.C., and Lisk, D.J. Chemical speciation influences comparative activity of selenium-enriched garlic and yeast in mammary cancer prevention. J. Agric. Food Chem. 48, 2062-2070 (2000).
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(2000)
J. Agric. Food Chem
, vol.48
, pp. 2062-2070
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Ip, C.1
Birringer, M.2
Block, E.3
Kotrebai, M.4
Tyson, J.F.5
Uden, P.C.6
Lisk, D.J.7
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12
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0034214376
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In vitro and in vivo studies of methylseleninic acid: Evidence that a monomethylated selenium metabolite is critical for cancer chemoprevention
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This was the first study to report that monom- ethylated selenium is more efficient in cancer prevention in mice than other selenium compounds and emphasized the role of small molecular weight selenocompounds in cancer prevention
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Ip, C., Thompson, H.J., Zhu, Z., and Ganther, H.E. In vitro and in vivo studies of methylseleninic acid: evidence that a monomethylated selenium metabolite is critical for cancer chemoprevention. Cancer Res. 60, 2882-2886 (2000). This was the first study to report that monom- ethylated selenium is more efficient in cancer prevention in mice than other selenium compounds and emphasized the role of small molecular weight selenocompounds in cancer prevention.
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(2000)
Cancer Res
, vol.60
, pp. 2882-2886
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Ip, C.1
Thompson, H.J.2
Zhu, Z.3
Ganther, H.E.4
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13
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52949144974
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Food-chain selenium and human health: Emphasis on intake
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Rayman, M.P. Food-chain selenium and human health: emphasis on intake. J. Nutr. 100, 254-268 (2008).
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(2008)
J. Nutr
, vol.100
, pp. 254-268
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Rayman, M.P.1
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14
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39749177838
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Targeting thioredoxin reductase 1 reduction in cancer cells inhibits self-sufficient growth and DNA replication
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Yoo, M.H., Xu, X.M., Carlson, B.A., Patterson, A.D., Gladyshev, V.N., and Hatfield, D.L. Targeting thioredoxin reductase 1 reduction in cancer cells inhibits self-sufficient growth and DNA replication. PLOS One 2, e1112 (2007).
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(2007)
PLOS One
, vol.2
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Yoo, M.H.1
Xu, X.M.2
Carlson, B.A.3
Patterson, A.D.4
Gladyshev, V.N.5
Hatfield, D.L.6
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15
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1942532136
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Selenium deficiency abrogates inflammation-dependent plasma cell tumors in mice
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This study was the first to report that selenium deficiency may protect against tumorigenesis development in some mouse cancer models
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Felix, K., Gerstmeier, S., Kyriakopoulos, A., Howard, O.M., Dong, H.F., Eckhaus, M., Behne, D., Bornkamm, G.W., and Janz, S. Selenium deficiency abrogates inflammation-dependent plasma cell tumors in mice. Cancer Res. 64, 2910-2917 (2004). This study was the first to report that selenium deficiency may protect against tumorigenesis development in some mouse cancer models.
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(2004)
Cancer Res
, vol.64
, pp. 2910-2917
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Felix, K.1
Gerstmeier, S.2
Kyriakopoulos, A.3
Howard, O.M.4
Dong, H.F.5
Eckhaus, M.6
Behne, D.7
Bornkamm, G.W.8
Janz, S.9
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16
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28544440524
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Selenoprotein deficiency and high levels of selenium compounds can effectively inhibit hepatocarcinogenesis in transgenic mice
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Novoselov, S.V., Calvisi, D.F., Labunskyy, V.M., Factor, V.M., Carlson, B.A., Fomenko, D.E., Moustafa, M.E., Hatfield, D.L., and Gladyshev, V.N. Selenoprotein deficiency and high levels of selenium compounds can effectively inhibit hepatocarcinogenesis in transgenic mice. Oncogene 24, 8003-8011 (2005).
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(2005)
Oncogene
, vol.24
, pp. 8003-8011
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Novoselov, S.V.1
Calvisi, D.F.2
Labunskyy, V.M.3
Factor, V.M.4
Carlson, B.A.5
Fomenko, D.E.6
Moustafa, M.E.7
Hatfield, D.L.8
Gladyshev, V.N.9
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17
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39149111228
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Lung cancer risk associated with selenium status is modified in smoking individuals by Sep15 polymorphism
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Jablonska, E., Gromadzinska, J., Sobala, W., Reszka, E., and Wasowicz, W. Lung cancer risk associated with selenium status is modified in smoking individuals by Sep15 polymorphism. Eur. J. Nutr. 47, 47-54 (2008).
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(2008)
Eur. J. Nutr
, vol.47
, pp. 47-54
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Jablonska, E.1
Gromadzinska, J.2
Sobala, W.3
Reszka, E.4
Wasowicz, W.5
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18
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52649149195
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Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma
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Peters, U., Chatterjee, N., Hayes, R.B., Schoen, R.E., Wang, Y., Chanock, S.J., and Foster, C.B. Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. Cancer Epidemiol. Biomarkers Prev. 17, 1144-1154 (2008).
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(2008)
Cancer Epidemiol. Biomarkers Prev
, vol.17
, pp. 1144-1154
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Peters, U.1
Chatterjee, N.2
Hayes, R.B.3
Schoen, R.E.4
Wang, Y.5
Chanock, S.J.6
Foster, C.B.7
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19
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38149115450
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Evidence that a polymorphism within the 3' UTR of glutathione peroxidase 4 is functional and is associated with susceptibility to colorectal cancer
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Bermano, G., Pagmantidis, V., Holloway, N. et al. Evidence that a polymorphism within the 3' UTR of glutathione peroxidase 4 is functional and is associated with susceptibility to colorectal cancer. Genes Nutr. 2, 225-232 (2007).
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(2007)
Genes Nutr
, vol.2
, pp. 225-232
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Bermano, G.1
Pagmantidis, V.2
Holloway, N.3
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20
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57749099101
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Interaction between single nucleotide polymorphisms in selenoprotein P and mitochondrial superoxide dismutase determines prostate cancer risk
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Cooper, M.L., Adami, H.O., Grönberg, H., Wiklund, F., Green, F.R., and Rayman, M.P. Interaction between single nucleotide polymorphisms in selenoprotein P and mitochondrial superoxide dismutase determines prostate cancer risk. Cancer Res. 68, 10171-10177 (2008).
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(2008)
Cancer Res
, vol.68
, pp. 10171-10177
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Cooper, M.L.1
Adami, H.O.2
Grönberg, H.3
Wiklund, F.4
Green, F.R.5
Rayman, M.P.6
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21
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33846343236
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Biosynthesis of selenocysteine on its tRNA in Eukaryotes
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This study reported the discovery of the mechanism of selenocysteine biosynthesis in eukaryotes and established the biosynthetic pathway of this twenty-first amino acid in the genetic code in these organisms
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Xu, X.M., Carlson, B.A., Mix, H., Zhang, Y., Saira, K., Glass, R.S., Berry, M.J., Gladyshev, V.N., and Hatfield, D.L. Biosynthesis of selenocysteine on its tRNA in Eukaryotes. PLOS Biol. 5, e4 (2006). This study reported the discovery of the mechanism of selenocysteine biosynthesis in eukaryotes and established the biosynthetic pathway of this twenty-first amino acid in the genetic code in these organisms.
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(2006)
PLOS Biol
, vol.5
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Xu, X.M.1
Carlson, B.A.2
Mix, H.3
Zhang, Y.4
Saira, K.5
Glass, R.S.6
Berry, M.J.7
Gladyshev, V.N.8
Hatfield, D.L.9
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22
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0038442808
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Characterization of mammalian selenoproteomes
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This study reported the full set of selenoprotein genes (25 genes) in the human genome
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Kryukov, G.V., Castellano, S., Novoselov, S.V., Lobanov, A.V., Zehtab, O., Guigo, R., and Gladyshev, V.N. Characterization of mammalian selenoproteomes. Science 300, 1439-1443 (2003). This study reported the full set of selenoprotein genes (25 genes) in the human genome.
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(2003)
Science
, vol.300
, pp. 1439-1443
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Kryukov, G.V.1
Castellano, S.2
Novoselov, S.V.3
Lobanov, A.V.4
Zehtab, O.5
Guigo, R.6
Gladyshev, V.N.7
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23
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33645732063
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Bioavailability of selenium in foods
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Finley, J.W. Bioavailability of selenium in foods. Nutri. Rev. 64, 146-151, (2006).
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(2006)
Nutri. Rev
, vol.64
, pp. 146-151
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Finley, J.W.1
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24
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55149090265
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Selenium and anticarcinogenesis: Underlying mechanisms
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Jackson, M.I. and Combs, G.F., Jr. Selenium and anticarcinogenesis: Underlying mechanisms. Curr Opin Clin Nutr Metab Care. 11, 718-726 (2008).
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(2008)
Curr Opin Clin Nutr Metab Care
, vol.11
, pp. 718-726
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Jackson, M.I.1
Combs Jr., G.F.2
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