Estrogen supplementation decreases norepinephrine-induced vasoconstriction and total body norepinephrine spillover in perimenopausal women

Hypertension

Volumn 30, Issue 6, 1997, Pages 1538-1543

  Sudhir, Krishnankutty ^a,b   Esler, Murray D ^a   Jennings, Garry L ^a   Komesaroff, Paul A ^a  

^a ALFRED HOSPITAL   (Australia)

^b BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

Angiotensin II; Estrogen; Norepinephrine; Sympathetic nervous system; Vasoconstriction

Indexed keywords

ANGIOTENSIN; ESTRADIOL VALERATE; NORADRENALIN; PLACEBO;

ADULT; ARTICLE; BLOOD VESSEL TONE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; ESTROGEN THERAPY; FEMALE; HEART PROTECTION; HUMAN; MENOPAUSE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SYMPATHETIC NERVE; VASOCONSTRICTION;

EID: 0030723880     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.30.6.1538     Document Type: Article

References (42)

1. Barrett-Connor E, Bush TL. Estrogen and coronary heart disease in women. JAMA. 1991;265:1861-1867.
2. Volterrani M, Rosano G, Coats A, Beale C, Collins P. Estrogen acutely increases peripheral blood flow in postmenopausal women. Am J Med. 1995;99:119-122.
3. Jiang CW, Sarrel PM, Lindsay DC, Poole-Wilson PA, Collins P. Endothelium-independent relaxation of rabbit coronary artery by 17beta-oestradiol in vitro. Br J Pharmacol. 1991;104:1033-1037.
4. Sudhir K, Chou TM, Mullen WL, Hausmann D, Collins P, Yock PG, Chatterjee K. Mechanisms of estrogen-induced vasodilation: in vivo studies in canine coronary conductance and resistance arteries. J Am Coll Cardiol. 1995;26:807-814.
5. Ford SP, Reynolds LP, Farley DB, Bhatnagar RK, Van Orden DE. Interaction of ovarian steroids and periarterial alpha 1-adrenergic receptors in altering uterine blood flow during the estrous cycle of gilts. Am J Obstet Gynecol. 1984;150:480-484.
6. Iversen LL. Catecholamine uptake processes. Br Med Bull. 1973; 29:130-135.
7. Manhem K, Hansson L, Milsom I, Pilhall M, Jern S. Estrogen and progestagen modify the hemodynamic response to mental stress in young women. Acta Obstet Gynecol Scand. 1996;75:57-62.
8. Owens JF, Stoney CM, Matthews KA. Menopausal status influences ambulatory blood pressure levels and blood pressure changes during mental stress. Circulation. 1993;88:2794-2802.
9. Lindheim SR, Legro RS, Bernstein L, Stanczyk FZ, Vijod MA. Presser SC, Lobo RA. Behavioral stress responses in premenopausal and postmenopausal women and the effects of estrogen. Am J Obstet Gynecol. 1992;167:1831-1836.
10. Esler M, Jackman G, Bobik A, Kelleher D, Jennings G, Leonard P, Skews H, Korner P. Determination of norepinephrine apparent release rate and clearance in humans. Life Sci. 1979;25:1461-1470.
11. Esler M. Assessment of sympathetic nervous function in humans from noradrenaline plasma kinetics. Clin Sci. 1982;62:247-254.
12. Esler M, Jennings G, Korner P, Willett I, Dudley F, Hasking G, Anderson W, Lambert G. Assessment of human sympathetic nervous system activity from measurements of norepinephrine turnover. Hypertension. 1988;11:3-20.
13. Cox HS, Kaye DM, Thompson JM, Turner AG, Jennings GL, Itsiopoulos C, Esler MD. Regional sympathetic nervous activation after a large meal in humans. Clin Sci. 1995;89:145-154.
14. Shan J, Resnick LM, Liu QY, Wu XC, Barbagallo M, Pang PK. Vascular effects of 17 beta-estradiol in male Sprague-Dawley rats. Am J Physiol. 1994;266:H967-H973.
15. Kondo K, Okuno T, Eguchi T, Yasui T, Suzuki H, Nagahama S, Saruta T. Vascular action of high dose estrogen in rats. Endocrin J. 1980;27:307-313.
16. Cheng DY, Gruetter CA. Chronic estrogen alters contractile responsiveness to angiotensin II and norepinephrine in female rat aorta. Eur J Pharmacol 1992;215:171-176.
17. Colucci WS, Gimbrone MA Jr, McLaughlin MK, Halpern W, Alexander RW. Increased vascular catecholamine sensitivity and alpha-adrenergic receptor affinity in female and estrogen-treated male rats. Circ Res. 1982;50:805-811.
18. Vargas R, Delaney, Farhat MY, Wolfe R, Rego A, Ramwell PW. Effect of estradiol 17 beta on pressor responses of rat mesenteric bed to norepinephrine, K+, and U-46619. J Cardiovasc Pharmacol. 1995;25:200-206.
19. Ettinger SM, Silber DH, Collins BG, Gray KS, Sutliff G, Whisler SK, McClain JM, Smith MB, Yang QX, Sinoway LI. Influences of gender on sympathetic nerve responses to static exercise. J Appl Physiol. 1996;80:245-251.
20. Sudhir K, Jennings GL, Funder JW, Komesaroff PA. Estrogen enhances basal nitric oxide release in the forearm vasculature in perimenopausal women. Hypertension. 1996;28:330-334.
21. Vita JA, Treasure CB, Yeung AC, Vekshtein VI, Fantasia GM, Fish RD, Ganz P, Selwyn AP. Patients with evidence of coronary endothelial dysfunction as assessed by acetylcholine infusion demonstrate marked increase in sensitivity to constrictor effects of catecholamines. Circulation. 1992;85:1390-1397.
22. Proudler AJ, Ahmed AI, Crook D, Fogelman I, Rymer JM, Stevenson JC. Hormone replacement therapy and serum angiotensin-converting-enzyme activity in postmenopausal women. Lancet. 1995;346:89-90.
23. Alonso-Solis R, Abreu P, Lopez-Coviella I, Hernandez G, Fajardo N, Hernandez-Diaz F, Diaz-Cruz A, Hernandez A. Gonadal steroid modulation of neuroendocrine transduction: a transynaptic view. Cell Mol Neurobiol. 1996;16:357-382.
24. Ferrer M, Meyer M, Osol G. Estrogen replacement increases beta-adrenoceptor-mediated relaxation of rat mesenteric arteries. J Vasc Res. 1996;33:124-131.
25. Ortega-Corona BG, Garcia-Bulnes G, Esparza-Avalos N, Ponce-Monter H, Valencia-Sanchez A, Villanueva-Tello T, Gallegos Cigarroa A. Antiestrogen U23,469 induced alterations of catecholamine levels on plasma and central nervous system. Arch Med Res. 1993;24:27-31.
26. Etgen AM, Karkanias GB. Estrogen regulation of noradrenergic signaling in the hypothalamus. Psychoneuroendocrinology. 1994;19: 603-610.
27. Esler M, Jennings G, Lambert G, Meredith I, Home M, Eisenhofer G. Overflow of catecholamine neurotransmitters to the circulation: source, fate and functions. Phys Rev. 1990;70:963-985.
28. Esler M, Jennings G, Lambert G. Noradrenaline release and the pathophysiology of primary human hypertension. Am J Hypertens. 1989;2:140S-146S.
29. Hasking GJ, Esler MD, Jennings GL, Burton D, Johns JA, Korner PI. Norepinephrine spillover to plasma in patients with congestive heart failure: evidence of increased overall and cardiorenal sympathetic nervous activity. Circulation. 1986;73:615-621.
30. Meredith IT, Broughton A, Jennings GL, Esler MD. Evidence of a selective increase in cardiac sympathetic activity in patients with sustained ventricular arrhythmias. N Engl J Med. 1991;325:618-624.
31. Rajkumar C, Kingwell BA, Cameron JD, Mehra R, Waddell T, Christophidis N, Komesaroff PA, McGrath B, Jennings GL, Sudhir K, Dart AM. Hormonal therapy increases arterial compliance in postmenopausal women. J Am Coll Cardiol. 1997;30:350-356.
32. Crane MG, Harris JJ, Winsor W. Hypertension, oral contraceptive agents and conjugated estrogens. Ann Intern Med. 1971;74:13-21.
33. Pfeffer RI. Estrogen use, hypertension and stroke in postmenopausal women. J Chron Dis. 1978;31:389-398.
34. Writing Group for the PEPI Trial. Effects of estrogen or estrogen/ progestin regimens on heart disease risk factors in postmenopausal women: the Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial. JAMA. 1995;273:199-208.
35. Pallas KG, Holzwarth GJ, Stern MP, Lucas CP. The effect of conjugated estrogens on the renin-angiotensin system. J Clin Endocrinol Metab. 1977;44:1061-1068.
36. Nachtigall LE, Nachtigall RH, Nachtigall RD, Beckman EM. Estrogen replacement therapy II: a prospective study in the relationship to carcinoma and cardiovascular and metabolic problems. Obstet Gynecol. 1979;54:74-79.
37. Pfeffer RI, Kurosaki TT, Charlton SK. Estrogen use and blood pressure in later life. Am J Epidemiol. 1979;110:469-478.
38. Wren BG, Brown LB, Routledge DA. Differential clinical response to oestrogens after menopause. Med J Aust. 1982;2:329-332.
39. Barrett-Connor E, Wingard DL, Criqui MH. Post-menopausal estrogen use and heart disease risk factors in the 1980's. JAMA. 1989;261:2095-2100.
40. Luotola H. Blood pressure and hemodynamics in postmenopausal women during estradiol-17 beta substitution. Ann Clin Res. 1983; 15(suppl 38):1-121.
41. Hassager C, Riis BJ, Strom V, Guyene TT, Christiansen C. The long-term effect of oral and percutaneous estradiol on plasma renin substrate and blood pressure. Circulation. 1987;76:753-758.
42. Woods JW. Oral contraceptives and hypertension. Hypertension. 1988;11(suppl II):II-11-II-15.