메뉴 건너뛰기




Volumn 513, Issue 2, 2013, Pages 287-291

Akt1 as a putative regulator of Hox genes

Author keywords

Akt1; DNA methylation; Hox gene; In silico analysis

Indexed keywords

BISULFITE; HOX PROTEIN; MESSENGER RNA; PROTEIN KINASE B; PROTEIN KINASE B ALPHA; UNCLASSIFIED DRUG; UNTRANSLATED RNA;

EID: 84870760324     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2012.10.034     Document Type: Article
Times cited : (10)

References (36)
  • 1
    • 70350217448 scopus 로고    scopus 로고
    • Hox genes and segmentation of the hindbrain and axial skeleton
    • Alexander T., Nolte C., Krumlauf R. Hox genes and segmentation of the hindbrain and axial skeleton. Annu. Rev. Cell Dev. Biol. 2009, 25:431-456.
    • (2009) Annu. Rev. Cell Dev. Biol. , vol.25 , pp. 431-456
    • Alexander, T.1    Nolte, C.2    Krumlauf, R.3
  • 2
    • 1542781732 scopus 로고    scopus 로고
    • Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B
    • Bae S.S., Cho H., Mu J., Birnbaum M.J. Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B. J. Biol. Chem. 2003, 278:49530-49536.
    • (2003) J. Biol. Chem. , vol.278 , pp. 49530-49536
    • Bae, S.S.1    Cho, H.2    Mu, J.3    Birnbaum, M.J.4
  • 3
    • 33750951686 scopus 로고    scopus 로고
    • Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model
    • Bansal D., et al. Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:16924-16929.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 16924-16929
    • Bansal, D.1
  • 4
    • 33645214765 scopus 로고    scopus 로고
    • PKBalpha is required for adipose differentiation of mouse embryonic fibroblasts
    • Baudry A., Yang Z.Z., Hemmings B.A. PKBalpha is required for adipose differentiation of mouse embryonic fibroblasts. J. Cell Sci. 2006, 119:889-897.
    • (2006) J. Cell Sci. , vol.119 , pp. 889-897
    • Baudry, A.1    Yang, Z.Z.2    Hemmings, B.A.3
  • 5
    • 29144487990 scopus 로고    scopus 로고
    • Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing
    • Cao R., Tsukada Y., Zhang Y. Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing. Mol. Cell. 2005, 20:845-854.
    • (2005) Mol. Cell. , vol.20 , pp. 845-854
    • Cao, R.1    Tsukada, Y.2    Zhang, Y.3
  • 7
    • 66349106496 scopus 로고    scopus 로고
    • Leptin deficiency and beta-cell dysfunction underlie type 2 diabetes in compound Akt knockout mice
    • Chen W.S., et al. Leptin deficiency and beta-cell dysfunction underlie type 2 diabetes in compound Akt knockout mice. Mol. Cell. Biol. 2009, 29:3151-3162.
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 3151-3162
    • Chen, W.S.1
  • 8
    • 0035448879 scopus 로고    scopus 로고
    • Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene
    • Chen W.S., et al. Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene. Genes Dev. 2001, 15:2203-2208.
    • (2001) Genes Dev. , vol.15 , pp. 2203-2208
    • Chen, W.S.1
  • 9
    • 0035914388 scopus 로고    scopus 로고
    • Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice
    • Cho H., Thorvaldsen J.L., Chu Q., Feng F., Birnbaum M.J. Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice. J. Biol. Chem. 2001, 276:38349-38352.
    • (2001) J. Biol. Chem. , vol.276 , pp. 38349-38352
    • Cho, H.1    Thorvaldsen, J.L.2    Chu, Q.3    Feng, F.4    Birnbaum, M.J.5
  • 10
    • 23144458500 scopus 로고    scopus 로고
    • Developmental regulation of the Hox genes during axial morphogenesis in the mouse
    • Deschamps J., van Nes J. Developmental regulation of the Hox genes during axial morphogenesis in the mouse. Development 2005, 132:2931-2942.
    • (2005) Development , vol.132 , pp. 2931-2942
    • Deschamps, J.1    van Nes, J.2
  • 11
    • 20044382806 scopus 로고    scopus 로고
    • Role for Akt3/protein kinase Bgamma in attainment of normal brain size
    • Easton R.M., et al. Role for Akt3/protein kinase Bgamma in attainment of normal brain size. Mol. Cell. Biol. 2005, 25:1869-1878.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 1869-1878
    • Easton, R.M.1
  • 12
    • 78650981194 scopus 로고    scopus 로고
    • A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability
    • Esteve P.O., et al. A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability. Nat. Struct. Mol. Biol. 2011, 18:42-48.
    • (2011) Nat. Struct. Mol. Biol. , vol.18 , pp. 42-48
    • Esteve, P.O.1
  • 13
    • 77955647352 scopus 로고    scopus 로고
    • The three-dimensional architecture of Hox cluster silencing
    • Ferraiuolo M.A., et al. The three-dimensional architecture of Hox cluster silencing. Nucleic Acids Res. 2010, 38:7472-7484.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 7472-7484
    • Ferraiuolo, M.A.1
  • 14
    • 1542328927 scopus 로고    scopus 로고
    • Structure, regulation and function of PKB/AKT-a major therapeutic target
    • Hanada M., Feng J., Hemmings B.A. Structure, regulation and function of PKB/AKT-a major therapeutic target. Biochim. Biophys. Acta 2004, 1697:3-16.
    • (2004) Biochim. Biophys. Acta , vol.1697 , pp. 3-16
    • Hanada, M.1    Feng, J.2    Hemmings, B.A.3
  • 15
    • 79956324593 scopus 로고    scopus 로고
    • Conserved, developmentally regulated mechanism couples chromosomal looping and heterochromatin barrier activity at the homeobox gene A locus
    • Kim Y.J., Cecchini K.R., Kim T.H. Conserved, developmentally regulated mechanism couples chromosomal looping and heterochromatin barrier activity at the homeobox gene A locus. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:7391-7396.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 7391-7396
    • Kim, Y.J.1    Cecchini, K.R.2    Kim, T.H.3
  • 16
    • 33748753073 scopus 로고    scopus 로고
    • Interplay between chromatin and trans-acting factors regulating the Hoxd4 promoter during neural differentiation
    • Kobrossy L., Rastegar M., Featherstone M. Interplay between chromatin and trans-acting factors regulating the Hoxd4 promoter during neural differentiation. J. Biol. Chem. 2006, 281:25926-25939.
    • (2006) J. Biol. Chem. , vol.281 , pp. 25926-25939
    • Kobrossy, L.1    Rastegar, M.2    Featherstone, M.3
  • 17
    • 0041426238 scopus 로고    scopus 로고
    • Analysis of plausible downstream target genes of Hoxc8 in F9 teratocarcinoma cells. Putative downstream target genes of Hoxc8
    • Kwon Y., Ko J.H., Byung-Gyu K., Kim M.H. Analysis of plausible downstream target genes of Hoxc8 in F9 teratocarcinoma cells. Putative downstream target genes of Hoxc8. Mol. Biol. Rep. 2003, 30:141-148.
    • (2003) Mol. Biol. Rep. , vol.30 , pp. 141-148
    • Kwon, Y.1    Ko, J.H.2    Byung-Gyu, K.3    Kim, M.H.4
  • 19
    • 34247594319 scopus 로고    scopus 로고
    • Jpk, a novel cell death inducer, regulates the expression of Hoxa7 in F9 teratocarcinoma cells, but not during apoptosis
    • Lee E.Y., Kim M.H. Jpk, a novel cell death inducer, regulates the expression of Hoxa7 in F9 teratocarcinoma cells, but not during apoptosis. Ann. N. Y. Acad. Sci. 2006, 1090:182-187.
    • (2006) Ann. N. Y. Acad. Sci. , vol.1090 , pp. 182-187
    • Lee, E.Y.1    Kim, M.H.2
  • 20
    • 84863738782 scopus 로고    scopus 로고
    • Chromatin organization and transcriptional activation of Hox genes
    • Lee J.Y., Min H., Wang X., Khan A.A., Kim M.H. Chromatin organization and transcriptional activation of Hox genes. Anat. Cell. Biol. 2010, 43:78-85.
    • (2010) Anat. Cell. Biol. , vol.43 , pp. 78-85
    • Lee, J.Y.1    Min, H.2    Wang, X.3    Khan, A.A.4    Kim, M.H.5
  • 21
    • 33749325080 scopus 로고    scopus 로고
    • Genomic evolution of Hox gene clusters
    • Lemons D., McGinnis W. Genomic evolution of Hox gene clusters. Science 2006, 313:1918-1922.
    • (2006) Science , vol.313 , pp. 1918-1922
    • Lemons, D.1    McGinnis, W.2
  • 22
    • 57249103576 scopus 로고    scopus 로고
    • Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: methylation of the E-cadherin promoter
    • (2140 e1-8)
    • Lim S.O., et al. Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: methylation of the E-cadherin promoter. Gastroenterology 2008, 135:2128-2140. (2140 e1-8).
    • (2008) Gastroenterology , vol.135 , pp. 2128-2140
    • Lim, S.O.1
  • 23
    • 57749106585 scopus 로고    scopus 로고
    • Breast cancer-associated fibroblasts confer AKT1-mediated epigenetic silencing of cystatin M in epithelial cells
    • Lin H.J., et al. Breast cancer-associated fibroblasts confer AKT1-mediated epigenetic silencing of cystatin M in epithelial cells. Cancer Res. 2008, 68:10257-10266.
    • (2008) Cancer Res. , vol.68 , pp. 10257-10266
    • Lin, H.J.1
  • 24
    • 76649112380 scopus 로고    scopus 로고
    • The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients
    • Lin R.K., et al. The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients. J. Clin. Invest. 2010, 120:521-532.
    • (2010) J. Clin. Invest. , vol.120 , pp. 521-532
    • Lin, R.K.1
  • 25
    • 77957122940 scopus 로고    scopus 로고
    • Transcriptional and post-transcriptional control of DNA methyltransferase 3B is regulated by phosphatidylinositol 3 kinase/Akt pathway in human hepatocellular carcinoma cell lines
    • Mei C., et al. Transcriptional and post-transcriptional control of DNA methyltransferase 3B is regulated by phosphatidylinositol 3 kinase/Akt pathway in human hepatocellular carcinoma cell lines. J. Cell. Biochem. 2010, 111:158-167.
    • (2010) J. Cell. Biochem. , vol.111 , pp. 158-167
    • Mei, C.1
  • 26
    • 28944438404 scopus 로고    scopus 로고
    • Modulating Hox gene functions during animal body patterning
    • Pearson J.C., Lemons D., McGinnis W. Modulating Hox gene functions during animal body patterning. Nat. Rev. Genet. 2005, 6:893-904.
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 893-904
    • Pearson, J.C.1    Lemons, D.2    McGinnis, W.3
  • 27
    • 34250729138 scopus 로고    scopus 로고
    • Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs
    • Rinn J.L., et al. Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell 2007, 129:1311-1323.
    • (2007) Cell , vol.129 , pp. 1311-1323
    • Rinn, J.L.1
  • 28
    • 77951957130 scopus 로고    scopus 로고
    • Chromatin compaction at Hox loci: a polycomb tale beyond histone tails
    • Simon J.A. Chromatin compaction at Hox loci: a polycomb tale beyond histone tails. Mol. Cell. 2010, 38:321-322.
    • (2010) Mol. Cell. , vol.38 , pp. 321-322
    • Simon, J.A.1
  • 29
    • 34548388292 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase/protein kinase B pathway stabilizes DNA methyltransferase I protein and maintains DNA methylation
    • Sun L., et al. Phosphatidylinositol 3-kinase/protein kinase B pathway stabilizes DNA methyltransferase I protein and maintains DNA methylation. Cell. Signal. 2007, 19:2255-2263.
    • (2007) Cell. Signal. , vol.19 , pp. 2255-2263
    • Sun, L.1
  • 30
    • 13444269203 scopus 로고    scopus 로고
    • Cdx protein interaction with Hoxa5 regulatory sequences contributes to Hoxa5 regional expression along the axial skeleton
    • Tabaries S., et al. Cdx protein interaction with Hoxa5 regulatory sequences contributes to Hoxa5 regional expression along the axial skeleton. Mol. Cell. Biol. 2005, 25:1389-1401.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 1389-1401
    • Tabaries, S.1
  • 31
    • 77952695371 scopus 로고    scopus 로고
    • Dnmt3b recruitment through E2F6 transcriptional repressor mediates germ-line gene silencing in murine somatic tissues
    • Velasco G., et al. Dnmt3b recruitment through E2F6 transcriptional repressor mediates germ-line gene silencing in murine somatic tissues. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:9281-9286.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 9281-9286
    • Velasco, G.1
  • 32
    • 79953748673 scopus 로고    scopus 로고
    • A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression
    • Wang K.C., et al. A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature 2011, 472:120-124.
    • (2011) Nature , vol.472 , pp. 120-124
    • Wang, K.C.1
  • 33
    • 67749093008 scopus 로고    scopus 로고
    • Hox genes and vertebrate axial pattern
    • Wellik D.M. Hox genes and vertebrate axial pattern. Curr. Top. Dev. Biol. 2009, 88:257-278.
    • (2009) Curr. Top. Dev. Biol. , vol.88 , pp. 257-278
    • Wellik, D.M.1
  • 34
    • 73149111929 scopus 로고    scopus 로고
    • A region of the human HOXD cluster that confers polycomb-group responsiveness
    • Woo C.J., Kharchenko P.V., Daheron L., Park P.J., Kingston R.E. A region of the human HOXD cluster that confers polycomb-group responsiveness. Cell 2010, 140:99-110.
    • (2010) Cell , vol.140 , pp. 99-110
    • Woo, C.J.1    Kharchenko, P.V.2    Daheron, L.3    Park, P.J.4    Kingston, R.E.5
  • 35
    • 46349105014 scopus 로고    scopus 로고
    • Cooperation between EZH2, NSPc1-mediated histone H2A ubiquitination and Dnmt1 in HOX gene silencing
    • Wu X., Gong Y., Yue J., Qiang B., Yuan J., Peng X. Cooperation between EZH2, NSPc1-mediated histone H2A ubiquitination and Dnmt1 in HOX gene silencing. Nucleic Acids Res. 2008, 36:3590-3599.
    • (2008) Nucleic Acids Res. , vol.36 , pp. 3590-3599
    • Wu, X.1    Gong, Y.2    Yue, J.3    Qiang, B.4    Yuan, J.5    Peng, X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.