메뉴 건너뛰기




Volumn 6, Issue , 2011, Pages 401-422

p53 and Ras mutations in cancer and experimental carcinogenesis

Author keywords

[No Author keywords available]

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; AFLATOXIN; CIGARETTE SMOKE; GUANOSINE TRIPHOSPHATASE; K RAS PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; POLYCYCLIC AROMATIC HYDROCARBON; PROTEIN P53; RAF PROTEIN; RAS PROTEIN;

EID: 84870720966     PISSN: 09400745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61737-995-6_18     Document Type: Article
Times cited : (2)

References (82)
  • 1
    • 63049136592 scopus 로고    scopus 로고
    • A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis
    • Adorno, M., Cordenonsi, M., et al. (2009). A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis. Cell 137: 87-98.
    • (2009) Cell , vol.137 , pp. 87-98
    • Adorno, M.1    Cordenonsi, M.2
  • 3
    • 0020586334 scopus 로고
    • Mouse skin carcinomas induced in vivo by chemical carcinogens have a transforming Harvey-ras oncogene
    • Balmain, A. and Pragnell, I.B. (1983). Mouse skin carcinomas induced in vivo by chemical carcinogens have a transforming Harvey-ras oncogene. Nature 303: 72-4.
    • (1983) Nature , vol.303 , pp. 72-74
    • Balmain, A.1    Pragnell, I.B.2
  • 4
    • 0021141757 scopus 로고
    • Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas
    • Balmain, A., Ramsden, M., et al. (1984). Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas. Nature 307: 658-60.
    • (1984) Nature , vol.307 , pp. 658-660
    • Balmain, A.1    Ramsden, M.2
  • 6
    • 0011493380 scopus 로고
    • Mutagenesis of the Ha-ras oncogene in mouse skin tumors induced by polycyclic aromatic hydrocarbons
    • Bizub, D., Wood, A.W., et al. (1986). Mutagenesis of the Ha-ras oncogene in mouse skin tumors induced by polycyclic aromatic hydrocarbons. Proc Natl Acad Sci USA 83: 6048-52.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 6048-6052
    • Bizub, D.1    Wood, A.W.2
  • 7
    • 0024376173 scopus 로고
    • ras oncogenes in human cancer: A review
    • Bos, J.L. (1989). ras oncogenes in human cancer: a review. Cancer Res 49: 4682-4689.
    • (1989) Cancer Res , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 8
    • 0023256456 scopus 로고
    • Prevalence of ras gene mutations in human colorectal cancers
    • Bos, J.L., Fearon, E.R., et al. (1987). Prevalence of ras gene mutations in human colorectal cancers. Nature 327: 293-7.
    • (1987) Nature , vol.327 , pp. 293-297
    • Bos, J.L.1    Fearon, E.R.2
  • 9
    • 0029911703 scopus 로고    scopus 로고
    • Dominant-negative p53 mutations selected in yeast hit cancer hot spots
    • Brachmann, R.K., Vidal, M., et al. (1996). Dominant-negative p53 mutations selected in yeast hit cancer hot spots. Proc Natl Acad Sci USA 93: 4091-4095.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 4091-4095
    • Brachmann, R.K.1    Vidal, M.2
  • 10
    • 0025038030 scopus 로고
    • Carcinogen-induced mutations in the mouse c-Ha-ras gene provide evidence of multiple pathways for tumor progression
    • Brown, K., Buchmann, A., et al. (1990). Carcinogen-induced mutations in the mouse c-Ha-ras gene provide evidence of multiple pathways for tumor progression. Proc Natl Acad Sci USA 87: 538-42.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 538-542
    • Brown, K.1    Buchmann, A.2
  • 11
    • 0026092941 scopus 로고
    • Mutational activation of the c-Ha-ras gene in liver tumors of different rodent strains: Correlation with susceptibility to hepatocarcinogenesis
    • Buchmann, A., Bauer-Hofmann, R., et al. (1991). Mutational activation of the c-Ha-ras gene in liver tumors of different rodent strains: correlation with susceptibility to hepatocarcinogenesis. Proc Natl Acad Sci USA 88: 911-5.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 911-915
    • Buchmann, A.1    Bauer-Hofmann, R.2
  • 12
    • 0035858984 scopus 로고    scopus 로고
    • p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements
    • Campomenosi, P., Monti, P., et al. (2001). p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements. Oncogene 20: 3573-9.
    • (2001) Oncogene , vol.20 , pp. 3573-3579
    • Campomenosi, P.1    Monti, P.2
  • 13
    • 0023729242 scopus 로고
    • c-H-ras-1 expression in 7,12-dimethyl benzanthraceneinduced Balb/c mouse mammary hyperplasias and their tumors
    • Cardiff, R.D., Gumerlock, P.H., et al. (1988). c-H-ras-1 expression in 7,12-dimethyl benzanthraceneinduced Balb/c mouse mammary hyperplasias and their tumors. Oncogene 3: 205-13.
    • (1988) Oncogene , vol.3 , pp. 205-213
    • Cardiff, R.D.1    Gumerlock, P.H.2
  • 14
    • 16644370412 scopus 로고    scopus 로고
    • Human RAS superfamily proteins and related GTPases
    • Colicelli, J. (2004). Human RAS superfamily proteins and related GTPases. Sci STKE 2004: RE13.
    • (2004) Sci STKE , vol.2004
    • Colicelli, J.1
  • 15
    • 0020431144 scopus 로고
    • Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons. G.H.A. Clowes Memorial Lecture
    • Conney, A.H. (1982). Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons. G.H.A. Clowes Memorial Lecture. Cancer Res 42: 4875-917.
    • (1982) Cancer Res , vol.42 , pp. 4875-4917
    • Conney, A.H.1
  • 16
    • 0029806936 scopus 로고    scopus 로고
    • Preferential formation of benzo[a]pyrene adducts at lung cancer mutation hotspots in P53
    • Denissenko, M.F., Pao, A., et al. (1996). Preferential formation of benzo[a]pyrene adducts at lung cancer mutation hotspots in P53. Science 274: 430-2.
    • (1996) Science , vol.274 , pp. 430-432
    • Denissenko, M.F.1    Pao, A.2
  • 17
    • 0032506782 scopus 로고    scopus 로고
    • The p53 codon 249 mutational hotspot in hepatocellular carcinoma is not related to selective formation or persistence of aflatoxin B1 adducts
    • Denissenko, M.F., Koudriakova, T.B., et al. (1998a). The p53 codon 249 mutational hotspot in hepatocellular carcinoma is not related to selective formation or persistence of aflatoxin B1 adducts. Oncogene 17: 3007-14.
    • (1998) Oncogene , vol.17 , pp. 3007-3014
    • Denissenko, M.F.1    Koudriakova, T.B.2
  • 18
    • 0032510267 scopus 로고    scopus 로고
    • Slow repair of bulky DNA adducts along the nontranscribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers
    • Denissenko, M.F., Pao, A., et al. (1998b). Slow repair of bulky DNA adducts along the nontranscribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers. Oncogene 16: 1241-7.
    • (1998) Oncogene , vol.16 , pp. 1241-1247
    • Denissenko, M.F.1    Pao, A.2
  • 19
    • 0023906067 scopus 로고
    • Concomitant K-and N-ras gene point mutations in clonal murine lymphoma
    • Diamond, L.E., Guerrero, I., et al. (1988). Concomitant K-and N-ras gene point mutations in clonal murine lymphoma. Mol Cell Biol 8: 2233-6.
    • (1988) Mol Cell Biol , vol.8 , pp. 2233-2236
    • Diamond, L.E.1    Guerrero, I.2
  • 20
    • 0037120955 scopus 로고    scopus 로고
    • Preferential DNA damage and poor repair determine ras gene mutational hotspot in human cancer
    • Feng, Z., Hu, W., et al. (2002). Preferential DNA damage and poor repair determine ras gene mutational hotspot in human cancer. J Natl Cancer Inst 94: 1527-36.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1527-1536
    • Feng, Z.1    Hu, W.2
  • 21
    • 0037717036 scopus 로고    scopus 로고
    • Chromium(VI) exposure enhances polycyclic aromatic hydrocarbon-DNA binding at the p53 gene in human lung cells
    • Feng, Z., Hu, W., et al. (2003). Chromium(VI) exposure enhances polycyclic aromatic hydrocarbon-DNA binding at the p53 gene in human lung cells. Carcinogenesis 24: 771-8.
    • (2003) Carcinogenesis , vol.24 , pp. 771-778
    • Feng, Z.1    Hu, W.2
  • 22
    • 33750282261 scopus 로고    scopus 로고
    • Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair
    • Feng, Z., Hu, W., et al. (2006). Acrolein is a major cigarette-related lung cancer agent: preferential binding at p53 mutational hotspots and inhibition of DNA repair. Proc Natl Acad Sci USA 103: 15404-9.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 15404-15409
    • Feng, Z.1    Hu, W.2
  • 23
    • 0029043805 scopus 로고
    • A simple p53 functional assay for screening cell lines, blood, and tumors
    • Flaman, J.M., Frebourg, T., et al. (1995). A simple p53 functional assay for screening cell lines, blood, and tumors. Proc Natl Acad Sci USA 92: 3963-7.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3963-3967
    • Flaman, J.M.1    Frebourg, T.2
  • 24
    • 0019074870 scopus 로고
    • Benzo[a]pyrene metabolism, activation and carcinogenesis: Role and regulation of mixed function oxidases and related enzymes
    • Gelboin, H.V. (1980). Benzo[a]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed function oxidases and related enzymes. Physiol Rev 60: 1107-66.
    • (1980) Physiol Rev , vol.60 , pp. 1107-1166
    • Gelboin, H.V.1
  • 25
    • 20644457543 scopus 로고    scopus 로고
    • Role of metabolism and viruses in aflatoxin-induced liver cancer
    • Groopman, J.D. and Kensler, T.W. (2005). Role of metabolism and viruses in aflatoxin-induced liver cancer. Toxicol Appl Pharmacol 206: 131-7.
    • (2005) Toxicol Appl Pharmacol , vol.206 , pp. 131-137
    • Groopman, J.D.1    Kensler, T.W.2
  • 26
    • 39049188036 scopus 로고    scopus 로고
    • Aflatoxin and hepatitis B virus biomarkers: A paradigm for complex environmental exposures and cancer risk
    • Groopman, J.D., Johnson, D., et al. (2005). Aflatoxin and hepatitis B virus biomarkers: a paradigm for complex environmental exposures and cancer risk. Cancer Biomark 1: 5-14.
    • (2005) Cancer Biomark , vol.1 , pp. 5-14
    • Groopman, J.D.1    Johnson, D.2
  • 27
    • 0023222283 scopus 로고
    • Mutational activation of oncogenes in animal model systems of carcinogenesis
    • Guerrero, I. and Pellicer, A. (1987). Mutational activation of oncogenes in animal model systems of carcinogenesis. Mutat Res 185: 293-308.
    • (1987) Mutat Res , vol.185 , pp. 293-308
    • Guerrero, I.1    Pellicer, A.2
  • 28
    • 0021362945 scopus 로고
    • A molecular approach to leukemogenesis: Mouse lymphomas contain an activated c-ras oncogene
    • Guerrero, I., Calzada, P., et al. (1984). A molecular approach to leukemogenesis: mouse lymphomas contain an activated c-ras oncogene. Proc Natl Acad Sci USA 81: 202-5.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 202-205
    • Guerrero, I.1    Calzada, P.2
  • 29
    • 0022366760 scopus 로고
    • Loss of the normal N-ras allele in a mouse thymic lymphoma induced by a chemical carcinogen
    • Guerrero, I., Villasante, A., et al. (1985). Loss of the normal N-ras allele in a mouse thymic lymphoma induced by a chemical carcinogen. Proc Natl Acad Sci U S A 82: 7810-4.
    • (1985) Proc Natl Acad Sci U S A , vol.82 , pp. 7810-7814
    • Guerrero, I.1    Villasante, A.2
  • 30
    • 0034745389 scopus 로고    scopus 로고
    • Patterns of p53 G-->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke
    • Hainaut, P. and Pfeifer, G.P. (2001). Patterns of p53 G-->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke. Carcinogenesis 22: 367-74.
    • (2001) Carcinogenesis , vol.22 , pp. 367-374
    • Hainaut, P.1    Pfeifer, G.P.2
  • 31
    • 0000953693 scopus 로고
    • An unidentified virus which causes the rapid production of tumours in mice
    • Harvey, J.J. (1964). An unidentified virus which causes the rapid production of tumours in mice. Nature 204: 1104-5.
    • (1964) Nature , vol.204 , pp. 1104-1105
    • Harvey, J.J.1
  • 32
    • 0031831381 scopus 로고    scopus 로고
    • Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines
    • Hecht, S.S. (1998). Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines. Chem Res Toxicol 11: 559-603.
    • (1998) Chem Res Toxicol , vol.11 , pp. 559-603
    • Hecht, S.S.1
  • 33
    • 0033591845 scopus 로고    scopus 로고
    • Tobacco smoke carcinogens and lung cancer
    • Hecht, S.S. (1999). Tobacco smoke carcinogens and lung cancer. J Natl Cancer Inst 91: 1194-210.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1194-1210
    • Hecht, S.S.1
  • 34
    • 0033060788 scopus 로고    scopus 로고
    • IARC p53 mutaion database: A relational database to compile and analyze p53 mutations in human tumors and cell lines. International Agency for research in cancer
    • Hernandez-Boussard, T., Rodriguez-Tome, P., et al. (1999). IARC p53 mutaion database: a relational database to compile and analyze p53 mutations in human tumors and cell lines. International Agency for research in cancer. Hum Mutat 14: 1-8.
    • (1999) Hum Mutat , vol.14 , pp. 1-8
    • Hernandez-Boussard, T.1    Rodriguez-Tome, P.2
  • 35
    • 0035902108 scopus 로고    scopus 로고
    • Genome maintenance mechanisms for preventing cancer
    • Hoeijmakers, J.H.J. (2001). Genome maintenance mechanisms for preventing cancer. Nature 411: 366-74.
    • (2001) Nature , vol.411 , pp. 366-374
    • Hoeijmakers, J.H.J.1
  • 36
    • 0025894713 scopus 로고
    • p53 mutations in human cancers
    • Hollstein, M., Sidransky, D., et al. (1991). p53 mutations in human cancers. Science 253: 49-53.
    • (1991) Science , vol.253 , pp. 49-53
    • Hollstein, M.1    Sidransky, D.2
  • 37
    • 0025732215 scopus 로고
    • Mutational hotspot in the p53 gene in human hepatocellular carcinomas
    • Hsu, I.C., Metcalf, R.A., et al. (1991). Mutational hotspot in the p53 gene in human hepatocellular carcinomas. Nature 350: 427-8.
    • (1991) Nature , vol.350 , pp. 427-428
    • Hsu, I.C.1    Metcalf, R.A.2
  • 38
    • 0027430658 scopus 로고
    • Screening patients for heterozygous p53 mutations using a functional assay in yeast
    • Ishioka, C., Frebourg, T., et al. (1993). Screening patients for heterozygous p53 mutations using a functional assay in yeast. Nat Genet 5: 124-9.
    • (1993) Nat Genet , vol.5 , pp. 124-129
    • Ishioka, C.1    Frebourg, T.2
  • 39
    • 0017000380 scopus 로고
    • Benzo[a]pyrene-nucleic acid derivative found in vivo: Structure of a benzo[a]pyrene-tetrahydrodiol epoxide-guanosine adduct
    • Jeffrey, A.M., Jennette, K.W., et al. (1976). Benzo[a]pyrene-nucleic acid derivative found in vivo: structure of a benzo[a]pyrene-tetrahydrodiol epoxide-guanosine adduct. J Am Chem Soc 98: 5714-5.
    • (1976) J Am Chem Soc , vol.98 , pp. 5714-5715
    • Jeffrey, A.M.1    Jennette, K.W.2
  • 40
    • 0017593561 scopus 로고
    • Nucleoside adducts from the in vitro reaction of benzo[a]pyrene-7,8-dihydrodiol-9,10-oxide or benzo[a]pyrene-4,5-oxide with nucleic acids
    • Jennette, K.W., Jeffery, A.M., et al. (1977). Nucleoside adducts from the in vitro reaction of benzo[a]pyrene-7,8-dihydrodiol-9,10-oxide or benzo[a]pyrene-4,5-oxide with nucleic acids. Biochemistry 16: 932-8.
    • (1977) Biochemistry , vol.16 , pp. 932-938
    • Jennette, K.W.1    Jeffery, A.M.2
  • 41
    • 0037816165 scopus 로고    scopus 로고
    • Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis
    • Kato, S., Han, S.Y., et al. (2003). Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis. Proc Natl Acad Sci USA 100: 8424-9.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8424-8429
    • Kato, S.1    Han, S.Y.2
  • 42
    • 0001446334 scopus 로고
    • Morphologic responses to a murine erythroblastosis virus
    • Kirsten, W.H. and Mayer, L.A. (1967). Morphologic responses to a murine erythroblastosis virus. J Natl Cancer Inst 39: 311-35.
    • (1967) J Natl Cancer Inst , vol.39 , pp. 311-335
    • Kirsten, W.H.1    Mayer, L.A.2
  • 43
    • 0018137343 scopus 로고
    • Binding of benzo[a]pyrene-7,8-diol-9,10-epoxides to DNA, RNA and protein of mouse skin occurs with high stereoselectivity
    • Koreeda, M., Moore, P.D., et al. (1978). Binding of benzo[a]pyrene-7,8-diol-9,10-epoxides to DNA, RNA and protein of mouse skin occurs with high stereoselectivity. Science 199: 778-81.
    • (1978) Science , vol.199 , pp. 778-781
    • Koreeda, M.1    Moore, P.D.2
  • 44
    • 0031284677 scopus 로고    scopus 로고
    • Aflatoxin B1-induced DNA adduct formation and p53 mutations in CYP450-expressing human liver cell lines
    • Mace, K., Aguilar, F., et al. (1997). Aflatoxin B1-induced DNA adduct formation and p53 mutations in CYP450-expressing human liver cell lines. Carcinogenesis 18: 1291-7.
    • (1997) Carcinogenesis , vol.18 , pp. 1291-1297
    • Mace, K.1    Aguilar, F.2
  • 45
    • 0026910856 scopus 로고
    • ras activation in experimental carcinogenesis
    • Mangues, R. and Pellicer, A. (1992). ras activation in experimental carcinogenesis. Semin Cancer Biol 3: 229-39.
    • (1992) Semin Cancer Biol , vol.3 , pp. 229-239
    • Mangues, R.1    Pellicer, A.2
  • 46
    • 0021133140 scopus 로고
    • Activation of c-Ha-ras-1 proto-oncogene by in vitro modification with a chemical carcinogen, benzo(a)pyrene diol-epoxide
    • Marshall, C.J., Vousden, K.H., et al. (1984). Activation of c-Ha-ras-1 proto-oncogene by in vitro modification with a chemical carcinogen, benzo(a)pyrene diol-epoxide. Nature 310: 586-9.
    • (1984) Nature , vol.310 , pp. 586-589
    • Marshall, C.J.1    Vousden, K.H.2
  • 47
    • 0025237186 scopus 로고
    • Transforming c-Ki-ras mutation is a preneoplastic event in mouse mammary carcinogenesis induced in vitro by N-methyl-N-nitrosourea
    • Miyamoto, S., Sukumar, S., et al. (1990). Transforming c-Ki-ras mutation is a preneoplastic event in mouse mammary carcinogenesis induced in vitro by N-methyl-N-nitrosourea. Mol Cell Biol 10: 1593-9.
    • (1990) Mol Cell Biol , vol.10 , pp. 1593-1599
    • Miyamoto, S.1    Sukumar, S.2
  • 48
    • 0036258111 scopus 로고    scopus 로고
    • The IARC TP53 database: New online mutation analysis and recommendations to users
    • Olivier, M., Eeles, R., et al. (2002). The IARC TP53 database: new online mutation analysis and recommendations to users. Hum Mutat 19: 607-14.
    • (2002) Hum Mutat , vol.19 , pp. 607-614
    • Olivier, M.1    Eeles, R.2
  • 49
    • 0017102363 scopus 로고
    • The reaction of (±)-7a,8b-dihydroxy-9b,10b-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene with DNA
    • Osborne, M.R., Beland, F.A., et al. (1976). The reaction of (±)-7a,8b-dihydroxy-9b,10b-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene with DNA. Int J Cancer 18: 362-8.
    • (1976) Int J Cancer , vol.18 , pp. 362-368
    • Osborne, M.R.1    Beland, F.A.2
  • 50
    • 0025889018 scopus 로고
    • Differential activation of ras genes by point mutation in human colon cancer with metastases to either lung or liver
    • Oudejans, J.J., Slebos, R.J., et al. (1991). Differential activation of ras genes by point mutation in human colon cancer with metastases to either lung or liver. Int J Cancer 49: 875-9.
    • (1991) Int J Cancer , vol.49 , pp. 875-879
    • Oudejans, J.J.1    Slebos, R.J.2
  • 51
    • 47549087168 scopus 로고    scopus 로고
    • The pattern of p53 mutations caused by PAH o-quinones is driven by 8-oxo-dGuo formation while the spectrum of mutations is determined by biological selection for dominance
    • Park, J.H., Gelhaus, S., et al. (2008a). The pattern of p53 mutations caused by PAH o-quinones is driven by 8-oxo-dGuo formation while the spectrum of mutations is determined by biological selection for dominance. Chem Res Toxicol 21: 1039-49.
    • (2008) Chem Res Toxicol , vol.21 , pp. 1039-1049
    • Park, J.H.1    Gelhaus, S.2
  • 52
    • 44349169635 scopus 로고    scopus 로고
    • Evidence for the aldo-keto reductase pathway of polycyclic aromatic trans-dihydrodiol activation in human lung A549 cells
    • Park, J.H., Mangal, D., et al. (2008b). Evidence for the aldo-keto reductase pathway of polycyclic aromatic trans-dihydrodiol activation in human lung A549 cells. Proc Natl Acad Sci USA 105: 6846-51.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 6846-6851
    • Park, J.H.1    Mangal, D.2
  • 53
    • 0032937593 scopus 로고    scopus 로고
    • Dihydrodiol dehydrogenases and polycyclic aromatic hydrocarbon activation: Generation of reactive and redox active o-quinones
    • Penning, T.M., Burczynski, M.E., et al. (1999). Dihydrodiol dehydrogenases and polycyclic aromatic hydrocarbon activation: generation of reactive and redox active o-quinones. Chem Res Toxicol 12: 1-18.
    • (1999) Chem Res Toxicol , vol.12 , pp. 1-18
    • Penning, T.M.1    Burczynski, M.E.2
  • 54
    • 0026356298 scopus 로고
    • Selective targeting of p53 gene mutational hotspots in human cancers by etiologically defined carcinogens
    • Puisieux, A., Lim, S., et al. (1991). Selective targeting of p53 gene mutational hotspots in human cancers by etiologically defined carcinogens. Cancer Res 51: 6185-9.
    • (1991) Cancer Res , vol.51 , pp. 6185-6189
    • Puisieux, A.1    Lim, S.2
  • 55
    • 42149192000 scopus 로고    scopus 로고
    • Activated Kras, but not Hras or Nras, may initiate tumors of endodermal origin via stem cell expansion
    • Quinlan, M.P., Quatela, S.E., et al. (2008). Activated Kras, but not Hras or Nras, may initiate tumors of endodermal origin via stem cell expansion. Mol Cell Biol 28: 2659-74.
    • (2008) Mol Cell Biol , vol.28 , pp. 2659-2674
    • Quinlan, M.P.1    Quatela, S.E.2
  • 56
    • 34547160398 scopus 로고    scopus 로고
    • Ras oncogenes and their downstream targets
    • Rajalingam, K., Schreck, R., et al. (2007). Ras oncogenes and their downstream targets. Biochim Biophys Acta 1773: 1177-95.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 1177-1195
    • Rajalingam, K.1    Schreck, R.2
  • 57
    • 0019960812 scopus 로고
    • A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene
    • Reddy, E.P., Reynolds, R.K., et al. (1982). A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene. Nature 300: 149-52.
    • (1982) Nature , vol.300 , pp. 149-152
    • Reddy, E.P.1    Reynolds, R.K.2
  • 58
    • 0023217707 scopus 로고
    • Activated oncogenes in B6C3F1 mouse liver tumors: Implications for risk assessment
    • Reynolds, S.H., Stowers, S.J., et al. (1987). Activated oncogenes in B6C3F1 mouse liver tumors: implications for risk assessment. Science 237: 1309-16.
    • (1987) Science , vol.237 , pp. 1309-1316
    • Reynolds, S.H.1    Stowers, S.J.2
  • 59
    • 0026909770 scopus 로고
    • ras and human tumors
    • Rodenhuis, S. (1992). ras and human tumors. Semin Cancer Biol 3: 241-7.
    • (1992) Semin Cancer Biol , vol.3 , pp. 241-247
    • Rodenhuis, S.1
  • 60
    • 0034710878 scopus 로고    scopus 로고
    • Human lung cancer and p53: The interplay between mutagenesis and selection
    • Rodin, S.N. and Rodin, A.S. (2000). Human lung cancer and p53: the interplay between mutagenesis and selection. Proc Natl Acad Sci USA 97: 12244-9.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12244-12249
    • Rodin, S.N.1    Rodin, A.S.2
  • 61
    • 0037206612 scopus 로고    scopus 로고
    • On the origin of p53 G:C--> T:A transversions in lung cancers
    • Rodin, S.N. and Rodin, A.S. (2002). On the origin of p53 G:C--> T:A transversions in lung cancers. Mutat Res 508: 1-19.
    • (2002) Mutat Res , vol.508 , pp. 1-19
    • Rodin, S.N.1    Rodin, A.S.2
  • 62
    • 12344292783 scopus 로고    scopus 로고
    • Origins and selection of p53 mutations in lung carcinogenesis
    • Rodin, S.N. and Rodin, A.S. (2005). Origins and selection of p53 mutations in lung carcinogenesis. Semin Cancer Biol 15: 103-112.
    • (2005) Semin Cancer Biol , vol.15 , pp. 103-112
    • Rodin, S.N.1    Rodin, A.S.2
  • 63
    • 0037196069 scopus 로고    scopus 로고
    • Cancerous hyper-mutagenesis in p53 genes is possibly associated with transcriptional bypass of DNA lesions
    • Rodin, S.N., Rodin, A.S., et al. (2002). Cancerous hyper-mutagenesis in p53 genes is possibly associated with transcriptional bypass of DNA lesions. Mutat Res 510: 153-68.
    • (2002) Mutat Res , vol.510 , pp. 153-168
    • Rodin, S.N.1    Rodin, A.S.2
  • 64
    • 0034429843 scopus 로고    scopus 로고
    • Mapping oxidative DNA damage using ligationmediated polymerase chain reaction technology
    • Rodriguez, H., Akman, S.A., et al. (2000). Mapping oxidative DNA damage using ligationmediated polymerase chain reaction technology. Methods 22: 148-56.
    • (2000) Methods , vol.22 , pp. 148-156
    • Rodriguez, H.1    Akman, S.A.2
  • 65
    • 0027333129 scopus 로고
    • G to A transitions and G to T transversions in codon 12 of the Ki-ras oncogene isolated from mouse lung tumors induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and related DNA methylating and pyridyloxobutylating agents
    • Ronai, Z.A., Gradia, S., et al. (1993). G to A transitions and G to T transversions in codon 12 of the Ki-ras oncogene isolated from mouse lung tumors induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and related DNA methylating and pyridyloxobutylating agents. Carcinogenesis 14: 2419-22.
    • (1993) Carcinogenesis , vol.14 , pp. 2419-2422
    • Ronai, Z.A.1    Gradia, S.2
  • 66
    • 0025732716 scopus 로고
    • High frequency mutation in codons 12 and 61 of H-ras oncogene in chewing tobacco-related human oral carcinoma in India
    • Saranath, D., Chang, S.E., et al. (1991). High frequency mutation in codons 12 and 61 of H-ras oncogene in chewing tobacco-related human oral carcinoma in India. Br J Cancer 63: 573-8.
    • (1991) Br J Cancer , vol.63 , pp. 573-578
    • Saranath, D.1    Chang, S.E.2
  • 67
    • 33845257339 scopus 로고    scopus 로고
    • Comparison of p53 mutations induced by PAH o-quinones with those caused by anti-benzo[a]pyrene diol epoxide in vitro: Role of reactive oxygen and biological selection
    • Shen, Y.M., Troxel, A.B., et al. (2006). Comparison of p53 mutations induced by PAH o-quinones with those caused by anti-benzo[a]pyrene diol epoxide in vitro: role of reactive oxygen and biological selection. Chem Res Toxicol 19: 1441-50.
    • (2006) Chem Res Toxicol , vol.19 , pp. 1441-1450
    • Shen, Y.M.1    Troxel, A.B.2
  • 68
    • 0030008731 scopus 로고    scopus 로고
    • Activation of chemically diverse procarcinogens by human cytochrome P450 1B1
    • Shimada, T., Hayes, C.L., et al. (1996). Activation of chemically diverse procarcinogens by human cytochrome P450 1B1. Cancer Res 56: 2979-84.
    • (1996) Cancer Res , vol.56 , pp. 2979-2984
    • Shimada, T.1    Hayes, C.L.2
  • 69
    • 0035067203 scopus 로고    scopus 로고
    • The chemistry and biology of aflatoxin B(1): From mutational spectrometry to carcinogenesis
    • Smela, M.E., Currier, S.S., et al. (2001). The chemistry and biology of aflatoxin B(1): from mutational spectrometry to carcinogenesis. Carcinogenesis 22: 535-45.
    • (2001) Carcinogenesis , vol.22 , pp. 535-545
    • Smela, M.E.1    Currier, S.S.2
  • 70
    • 0021074016 scopus 로고
    • Induction of mammary carcinomas in rats by nitrosomethylurea involves malignant activation of H-ras-1 locus by single point mutations
    • Sukumar, S., Notario, V., et al. (1983). Induction of mammary carcinomas in rats by nitrosomethylurea involves malignant activation of H-ras-1 locus by single point mutations. Nature 306: 658-61.
    • (1983) Nature , vol.306 , pp. 658-661
    • Sukumar, S.1    Notario, V.2
  • 71
    • 0028276386 scopus 로고
    • cDNA sequence of a human dioxin-inducible mRNA identifies a new gene subfamily of cytochrome P450 that maps to chromosome 2
    • Sutter, T.R., Tang, Y.M., et al. (1994). cDNA sequence of a human dioxin-inducible mRNA identifies a new gene subfamily of cytochrome P450 that maps to chromosome 2. J Biol Chem 269: 13092-9.
    • (1994) J Biol Chem , vol.269 , pp. 13092-13099
    • Sutter, T.R.1    Tang, Y.M.2
  • 72
    • 0019947771 scopus 로고
    • Mechanism of activation of a human oncogene
    • Tabin, C.J., Bradley, S.M., et al. (1982). Mechanism of activation of a human oncogene. Nature 300: 143-9.
    • (1982) Nature , vol.300 , pp. 143-149
    • Tabin, C.J.1    Bradley, S.M.2
  • 73
    • 0020404981 scopus 로고
    • Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change
    • Taparowsky, E., Suard, Y., et al. (1982). Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change. Nature 300: 762-5.
    • (1982) Nature , vol.300 , pp. 762-765
    • Taparowsky, E.1    Suard, Y.2
  • 74
    • 52949118488 scopus 로고    scopus 로고
    • Kras regulatory elements and exon 4A determine mutation specificity in lung cancer
    • To, M.D., Wong, C.E., et al. (2008). Kras regulatory elements and exon 4A determine mutation specificity in lung cancer. Nat Genet 40: 1240-4.
    • (2008) Nat Genet , vol.40 , pp. 1240-1244
    • To, M.D.1    Wong, C.E.2
  • 75
    • 0037220167 scopus 로고    scopus 로고
    • The TP53 gene, tobacco exposure, and lung cancer
    • Toyooka, S., Tsuda, T., et al. (2003). The TP53 gene, tobacco exposure, and lung cancer. Hum Mutat 21: 229-39.
    • (2003) Hum Mutat , vol.21 , pp. 229-239
    • Toyooka, S.1    Tsuda, T.2
  • 76
    • 0037199429 scopus 로고    scopus 로고
    • Formation of benzo[a]pyrene diol epoxide-DNA adducts at specific guanines within K-ras and p53 gene sequences: Stable isotope-labeling mass spectrometry approach
    • Tretyakova, N., Matter, B., et al. (2002). Formation of benzo[a]pyrene diol epoxide-DNA adducts at specific guanines within K-ras and p53 gene sequences: stable isotope-labeling mass spectrometry approach. Biochemistry 41: 9535-44.
    • (2002) Biochemistry , vol.41 , pp. 9535-9544
    • Tretyakova, N.1    Matter, B.2
  • 77
    • 0027160625 scopus 로고
    • Dose-dependent differences in the profile of mutations induced by (+)-7R,8S-dihydroxy-9S,10R-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in Chinese hamster V-79 cells
    • Wei, S.J., Chang, R.L., et al. (1993). Dose-dependent differences in the profile of mutations induced by (+)-7R,8S-dihydroxy-9S,10R-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in Chinese hamster V-79 cells. Cancer Res 53: 3294-301.
    • (1993) Cancer Res , vol.53 , pp. 3294-3301
    • Wei, S.J.1    Chang, R.L.2
  • 78
    • 0141567937 scopus 로고    scopus 로고
    • Mutagenesis of benzo[a]pyrene diol-epoxide in yeast: Requirement for DNA polymerase x and involvement of DNA polmerase h
    • Xie, Z., Braithwaite, E., et al. (2003). Mutagenesis of benzo[a]pyrene diol-epoxide in yeast: requirement for DNA polymerase x and involvement of DNA polmerase h. Biochemistry 42: 11253-62.
    • (2003) Biochemistry , vol.42 , pp. 11253-11262
    • Xie, Z.1    Braithwaite, E.2
  • 79
    • 0037264384 scopus 로고    scopus 로고
    • Simulated sunlight and benzo[a]pyrene diol epoxide induced mutagenesis in the human p53 gene evaluated by the yeast functional assay: Lack of correspondence to tumor mutation spectra
    • Yoon, J.H., Lee, C.S., et al. (2003). Simulated sunlight and benzo[a]pyrene diol epoxide induced mutagenesis in the human p53 gene evaluated by the yeast functional assay: lack of correspondence to tumor mutation spectra. Carcinogenesis 24: 113-9.
    • (2003) Carcinogenesis , vol.24 , pp. 113-119
    • Yoon, J.H.1    Lee, C.S.2
  • 80
    • 0007142725 scopus 로고
    • Activation of the Ki-ras protooncogene in spontaneously occurring and chemically induced lung tumors of the strain A mouse
    • You, M., Candrian, U., et al. (1989). Activation of the Ki-ras protooncogene in spontaneously occurring and chemically induced lung tumors of the strain A mouse. Proc Natl Acad Sci USA 86: 3070-4.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 3070-3074
    • You, M.1    Candrian, U.2
  • 81
    • 0035998283 scopus 로고    scopus 로고
    • Reactive oxygen species generated by PAH o-quinones cause change-in-function mutations in p53
    • Yu, D., Berlin, J.A., et al. (2002). Reactive oxygen species generated by PAH o-quinones cause change-in-function mutations in p53. Chem Res Toxicol 15: 832-42.
    • (2002) Chem Res Toxicol , vol.15 , pp. 832-842
    • Yu, D.1    Berlin, J.A.2
  • 82
    • 0021871265 scopus 로고
    • Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-Nmethylurea during initiation of mammary carcinogenesis in rats
    • Zarbl, H., Sukumar, S., et al. (1985). Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-Nmethylurea during initiation of mammary carcinogenesis in rats. Nature 315: 382-5.
    • (1985) Nature , vol.315 , pp. 382-385
    • Zarbl, H.1    Sukumar, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.