Role of leukotriene B4 receptor signaling in human preadipocyte differentiation

Biochemical and Biophysical Research Communications

Volumn 429, Issue 3-4, 2012, Pages 197-203

  Hirata, Kae ^a   Katayama, Kazufumi ^a   Nakajima, Atsushi ^b   Takada, Kenji ^a   Kamisaki, Yoshinori ^a   Wada, Koichiro ^a  

^a OSAKA UNIVERSITY   (Japan)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

Adipocyte; Differentiation; Human; Leukotriene; Preadipocyte; Receptor; SiRNA; TGFBI

Indexed keywords

LEUKOTRIENE B4 RECEPTOR; LIPOXYGENASE INHIBITOR; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR;

ADIPOSE TISSUE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ADIPOCYTES; ADIPOGENESIS; ANIMALS; CELLS, CULTURED; EXTRACELLULAR MATRIX PROTEINS; GENE KNOCKDOWN TECHNIQUES; HUMANS; LIPOXYGENASE INHIBITORS; MICE; RECEPTORS, LEUKOTRIENE B4; RNA, SMALL INTERFERING; TRANSFORMING GROWTH FACTOR BETA;

EID: 84870696203     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.10.110     Document Type: Article

References (20)

1. Fasshauer M., Paschke R. Regulation of adipocytokines and insulin resistance. Diabetologia 2003, 40:1594-1603.
2. Yudkin J.S. Inflammation, obesity, and the metabolic syndrome. Horm. Metab. Res. 2007, 39:707-709.
3. Kadowaki T., Hara K., Yamauchi T., Terauchi Y., Tobe K., Nagai R. Molecular mechanism of insulin resistance and obesity. Exp. Biol. Med. 2003, 228:1111-1117.
4. Samuelsson B., Dahlen S.E., Lindgren J.A., Rouzer C.A., Serhan C.N. Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. Science 1987, 237:1171-1176.
5. 4 biosynthesis. J. Biol. Chem. 2004, 279:50639-50642.
6. 4 that mediates chemotaxis. Nature 1997, 387:620-624.
7. Brink C., Dahlen S.E., Drazen J., Evans J.V., Hay D.W., Nicosia S., Serhan C.N., Shimizu T., Yokomizo T. International Union of Pharmacology XXXVII. Nomenclature for leukotriene and lipoxin receptors. Pharmacol. Rev. 2003, 55:195-227.
8. Claria J., Lee M.H., Serhan C.N. Aspirin-triggered lipoxins (15-epi-LX) are generated by human lung adenocarcinoma cell line (A549)-neutrophil interactions and are potent inhibitors of cell proliferation. Mol. Med. 1996, 2:583-596.
9. McMahon B., Mitchell D., Shattock R., Martin F., Brady H.R., Godson C. Lipoxin, leukotriene, and PDGF receptors cross-talk to regulate mesangial cell proliferation. FASEB J. 2002, 16:1817-1819.
10. Wada K., Arita M., Nakajima A., Katayama K., Kudo C., Kamisaki Y., Serhan C.N. Leukotriene B4 and lipoxin A4 are regulatory signals for neural stem cell proliferation and differentiation. FASEB J. 2006, 20:1785-1792.
11. Tontonoz P., Hu E., Graves R.A., Budavari A.I., Spiegelman B.M. mPPARgamma 2: tissue-specific regulator of an adipocyte enhancer. Genes Dev. 1994, 8:1224-1234.
12. Katayama K., Wada K., Miyoshi H., Ohashi K., Tachibana M., Furuki R., Mizuguchi H., Hayakawa T., Nakajima A., Kadowaki T., Tsutsumi Y., Nakagawa S., Kamisaki Y., Mayumi T. RNA interfering approach for clarifying the PPARγ pathway using lentiviral vector expressing short hairpin RNA. FEBS Lett. 2004, 560:178-182.
13. 2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation. Cell 1995, 83:813-819.
14. Evans R.M., Barish G.D., Wang Y.X. PPARs and the complex journey to obesity. Nat. Med. 2004, 10:1-7.
15. Skonier J., Neubauer M., Madisen L., Bennett K., Plowman G.D., Purchio A.F. cDNA cloning and sequence analysis of beta ig-h3, a novel gene induced in a human adenocarcinoma cell line after treatment with transforming growth factor-beta. DNA Cell Biol. 1992, 11:511-522.
16. Thapa N., Lee B.H., Kim I.S. TGFBIp/βig-h3 protein: a versatile matrix molecule induced by TGF-β. Int. J. Biochem. Cell Biol. 2007, 39:2183-2194.
17. Oh J.E., Kook J.K., Min B.M. βig-h3 induces keratinocyte differentiation via modulation of involucrin and transglutaminase expression through the integrin α3β1 and the phosphatidylinositol 3-kinase/Akt signaling pathway. J. Biol. Chem. 2006, 280:21629-21637.
18. 4 receptor 1 confers resistance to airway hyperresponsiveness and Th2-type immune responses. J. Immunol. 2005, 175:4217-4225.
19. 4 receptors BLT1 and BLT2: a critical role for BLT1 in collagen-induced arthritis in mice. J. Immunol. 2006, 176:6254-6261.
20. Mehrabian M., Schulthess F.T., Nebohacova M., Castellani L.W., Zhou Z., Hartiala J., Oberholzer J., Lusis A.J., Maedler K., Allayee H. Identification of ALOX5 as a gene regulating adiposity and pancreatic function. Diabetologia 2008, 51:978-988.