Lamin B1 Polymorphism Influences Morphology of the Nuclear Envelope, Cell Cycle Progression, and Risk of Neural Tube Defects in Mice

PLoS Genetics

Volumn 8, Issue 11, 2012, Pages

  de Castro, Sandra C P ^a   Malhas, Ashraf ^b   Leung, Kit Yi ^a   Gustavsson, Peter ^c   Vaux, David J ^b   Copp, Andrew J ^a   Greene, Nicholas D E ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE; GLUTAMIC ACID; LAMIN; LAMIN B1; PROTEIN P16; UNCLASSIFIED DRUG;

ALLELE; ANENCEPHALUS; ARTICLE; CELL CULTURE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL NUCLEUS MEMBRANE; CELL PROLIFERATION; CONTROLLED STUDY; DNA POLYMORPHISM; EMBRYO; FIBROBLAST; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GENE; GENE FUNCTION; GENETIC ANALYSIS; GENETIC RISK; GENETIC STABILITY; GENETIC STRAIN; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GRAINYHEAD LIKE 3 GENE; LAMIN B1 GENE; LOSS OF FUNCTION MUTATION; MODIFIER GENE; MOUSE; NONHUMAN; PENETRANCE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN STABILITY; PROTEOMICS; SENESCENCE; SPINAL DYSRAPHISM; TERATOLOGY;

ANIMALS; CELL CYCLE; CELL DIVISION; CELL PROLIFERATION; CELLS, CULTURED; CHROMOSOMAL PROTEINS, NON-HISTONE; DNA-BINDING PROTEINS; HUMANS; LAMIN TYPE B; MICE; MUTATION; NEURAL TUBE DEFECTS; NUCLEAR ENVELOPE; POLYMORPHISM, GENETIC; PROTEOMICS; SPINAL DYSRAPHISM; TRANSCRIPTION FACTORS;

MUS;

EID: 84870689582     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003059     Document Type: Article

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