Anti-angiogenesis and immunomodulatory activities of an anti-tumor sesquiterpene bigelovin isolated from Inula helianthus-aquatica

European Journal of Medicinal Chemistry

Volumn 59, Issue , 2013, Pages 243-252

  Yue, Grace G L ^a   Chan, Ben C L ^a   Kwok, Hin Fai ^a   Wong, Yuk Lau ^a   Leung, Hoi Wing ^a   Ji, Chang Jiu ^b   Fung, Kwok Pui ^a   Leung, Ping Chung ^a   Tan, Ning Hua ^b   Lau, Clara B S ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b KUNMING INSTITUTE OF BOTANY   (China)

Author keywords

Angiogenesis; Bigelovin; Cell adhesion molecules; HMEC 1; Inula helianthus aquatica; Zebrafish

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOPOIETIN 2; ANGIOPOIETIN RECEPTOR; BIGELOVIN; CELL ADHESION MOLECULE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GAMMA INTERFERON; INTERCELLULAR CELL ADHESION MOLECULE 1; INTERLEUKIN 12; INTERLEUKIN 2; PLANT EXTRACT; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; ARTICLE; BLOOD VESSEL; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG ISOLATION; EMBRYO; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOMODULATION; INULA; INULA HELIANTHUS AQUATICA; MULTIPLE SCLEROSIS; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; TH1 CELL; ZEBRA FISH;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTINEOPLASTIC AGENTS; CHINA; EMBRYO, NONMAMMALIAN; GENE EXPRESSION REGULATION; HELIANTHUS; HUMANS; IMMUNOLOGIC FACTORS; LACTONES; NEOVASCULARIZATION, PHYSIOLOGIC; PLANT EXTRACTS; PLANT LEAVES; SESQUITERPENES; U937 CELLS; ZEBRAFISH;

EID: 84870673106     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.11.029     Document Type: Article

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