메뉴 건너뛰기




Volumn 18, Issue 6, 2011, Pages 470-478

Anti-angiogenic effect and mechanism of rhein from Rhizoma Rhei

Author keywords

Angpt2; Anthraquinone; Anti angiogenesis; HUVECs; Rhein; Tie2; Zebrafish

Indexed keywords

RHEIN;

EID: 79955002345     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2010.10.006     Document Type: Article
Times cited : (67)

References (67)
  • 1
    • 28244456279 scopus 로고    scopus 로고
    • Tumor inflammatory angiogenesis and its chemoprevention
    • DOI 10.1158/0008-5472.CAN-05-3473
    • A. Albini, F. Tosetti, R. Benelli, and D.M. Noonan Tumor inflammatory angiogenesis and its chemoprevention Cancer Res. 65 2005 10637 10641 (Pubitemid 41713327)
    • (2005) Cancer Research , vol.65 , Issue.23 , pp. 10637-10641
    • Albini, A.1    Tosetti, F.2    Benelli, R.3    Noonan, D.M.4
  • 4
    • 41949120144 scopus 로고    scopus 로고
    • Combined anti-proliferative and anti-angiogenic strategies for cancer
    • DOI 10.1517/14656566.9.5.701
    • J. Bar, and A. Onn Combined anti-proliferative and anti-angiogenic strategies for cancer Exp. Opin. Pharmacother. 9 2008 701 715 (Pubitemid 351595945)
    • (2008) Expert Opinion on Pharmacotherapy , vol.9 , Issue.5 , pp. 701-715
    • Bar, J.1    Onn, A.2
  • 6
    • 77952577457 scopus 로고    scopus 로고
    • Angiogenesis: What can it offer for future medicine?
    • 10.1016/j.yexcr.2010.02.031
    • Y. Cao Angiogenesis: what can it offer for future medicine? Exp. Cell Res. 2010 10.1016/j.yexcr.2010.02.031
    • (2010) Exp. Cell Res.
    • Cao, Y.1
  • 7
    • 0033118504 scopus 로고    scopus 로고
    • Angiogenesis inhibited by drinking tea
    • Y. Cao, and R. Cao Angiogenesis inhibited by drinking tea Nature 398 1999 381
    • (1999) Nature , vol.398 , pp. 381
    • Cao, Y.1    Cao, R.2
  • 8
    • 0036305189 scopus 로고    scopus 로고
    • Antiangiogenic mechanisms of diet-derived polyphenols
    • DOI 10.1016/S0955-2863(02)00204-8, PII S0955286302002048
    • Y. Cao, R. Cao, and E. Brakenhielm Antiangiogenic mechanisms of diet-derived polyphenols J. Nutr. Biochem. 13 2002 380 390 (Pubitemid 34733007)
    • (2002) Journal of Nutritional Biochemistry , vol.13 , Issue.7 , pp. 380-390
    • Cao, Y.1    Cao, R.2    Brakenhielm, E.3
  • 9
    • 33846068065 scopus 로고    scopus 로고
    • Evaluation of the anti-angiogenic effect of aloe-emodin
    • DOI 10.1007/s00018-006-6399-6
    • C. Cardenas, A.R. Quesada, and M.A. Medina Evaluation of the anti-angiogenic effect of aloe-emodin Cell. Mol. Life Sci. 63 2006 3083 3089 (Pubitemid 46072310)
    • (2006) Cellular and Molecular Life Sciences , vol.63 , Issue.24 , pp. 3083-3089
    • Cardenas, C.1    Quesada, A.R.2    Medina, M.A.3
  • 10
    • 77950455995 scopus 로고    scopus 로고
    • Emodin, aloe-emodin and rhein inhibit migration and invasion in human tongue cancer SCC-4 cells through the inhibition of gene expression of matrix metalloproteinase-9
    • Y.Y. Chen, S.Y. Chiang, J.G. Lin, Y.S. Ma, C.L. Liao, S.W. Weng, T.Y. Lai, and J.G. Chung Emodin, aloe-emodin and rhein inhibit migration and invasion in human tongue cancer SCC-4 cells through the inhibition of gene expression of matrix metalloproteinase-9 Int. J. Oncol. 36 2010 1113 1120
    • (2010) Int. J. Oncol. , vol.36 , pp. 1113-1120
    • Chen, Y.Y.1    Chiang, S.Y.2    Lin, J.G.3    Ma, Y.S.4    Liao, C.L.5    Weng, S.W.6    Lai, T.Y.7    Chung, J.G.8
  • 11
    • 27844496880 scopus 로고    scopus 로고
    • Chinese Pharmacopoeia Commission, Chemical Industry Press Beijing
    • Chinese Pharmacopoeia Commission Pharmacopoeia of the People's Republic of China 2005 Chemical Industry Press Beijing p. 17
    • (2005) Pharmacopoeia of the People's Republic of China
  • 13
    • 0035056388 scopus 로고    scopus 로고
    • Topical anti-inflammatory activity of some Asian medicinal plants used in dermatological disorders
    • DOI 10.1016/S0367-326X(00)00305-1, PII S0367326X00003051
    • M.J. Cuellar, R.M. Giner, M.C. Recio, S. Manez, and J.L. Rios Topical anti-inflammatory activity of some Asian medicinal plants used in dermatological disorders Fitoterapia 72 2001 221 229 (Pubitemid 32273462)
    • (2001) Fitoterapia , vol.72 , Issue.3 , pp. 221-229
    • Cuellar, M.J.1    Giner, R.M.2    Recio, M.C.3    Maez, S.4    Rios, J.L.5
  • 14
    • 58049110537 scopus 로고    scopus 로고
    • Molecular mechanisms of VEGF-induced angiogenesis
    • S. Donnini, M. Ziche, and L. Morbidelli Molecular mechanisms of VEGF-induced angiogenesis J.H. Harmey, VEGF and Cancer 2004 Kluwer Academic/Plenum Publishing New York 19 25
    • (2004) VEGF and Cancer , pp. 19-25
    • Donnini, S.1    Ziche, M.2    Morbidelli, L.3
  • 15
    • 33847166239 scopus 로고    scopus 로고
    • Aloe(-emodin) for cancer? More than just a comforting salve
    • J.F. Dorsey, and G.D. Kao Aloe(-emodin) for cancer? More than just a comforting salve Cancer Biol. Ther. 6 2007 89 90 (Pubitemid 46294183)
    • (2007) Cancer Biology and Therapy , vol.6 , Issue.1 , pp. 89-90
    • Dorsey, J.F.1    Kao, G.D.2
  • 16
    • 47949089077 scopus 로고    scopus 로고
    • VEGF-targeted therapy: Mechanisms of anti-tumour activity
    • L.M. Ellis, and D.J. Hicklin VEGF-targeted therapy: mechanisms of anti-tumour activity Nat. Rev. Cancer 8 2008 579 591
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 579-591
    • Ellis, L.M.1    Hicklin, D.J.2
  • 17
    • 33751225092 scopus 로고    scopus 로고
    • Angiopoietins: A link between angiogenesis and inflammation
    • DOI 10.1016/j.it.2006.10.004, PII S1471490606002936
    • U. Fiedler, and H.G. Augustin Angiopoietins: a link between angiogenesis and inflammation Trends Immunol. 27 2006 552 558 (Pubitemid 44780853)
    • (2006) Trends in Immunology , vol.27 , Issue.12 , pp. 552-558
    • Fiedler, U.1    Augustin, H.G.2
  • 18
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • J. Folkman Tumor angiogenesis: therapeutic implications N. Engl. J. Med. 285 1971 1182 1186
    • (1971) N. Engl. J. Med. , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 19
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • J. Folkman Angiogenesis in cancer, vascular, rheumatoid and other disease Nat. Med. 1 1995 27 31
    • (1995) Nat. Med. , vol.1 , pp. 27-31
    • Folkman, J.1
  • 20
    • 0033135876 scopus 로고    scopus 로고
    • Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development
    • N.W. Gale, and G.D. Yancopoulos Growth factors acting via endothelial cellspecific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development Genes Dev. 13 1999 1055 1066 (Pubitemid 29233137)
    • (1999) Genes and Development , vol.13 , Issue.9 , pp. 1055-1066
    • Gale, N.W.1    Yancopoulos, G.D.2
  • 21
    • 2942572943 scopus 로고    scopus 로고
    • In vivo and in vitro evaluation of erianin, a novel anti-angiogenic agent
    • DOI 10.1016/j.ejca.2004.01.041, PII S095980490400231X
    • Y.Q. Gong, Y. Fan, D.Z. Wu, H. Yang, Z.B. Hu, and Z.T. Wang In vivo and in vitro evaluation of erianin, a novel anti-angiogenic agent Eur. J. Cancer 40 2004 1554 1565 (Pubitemid 38757744)
    • (2004) European Journal of Cancer , vol.40 , Issue.10 , pp. 1554-1565
    • Gong, Y.-Q.1    Fan, Y.2    Wu, D.-Z.3    Yang, H.4    Hu, Z.-B.5    Wang, Z.-T.6
  • 22
    • 48149105835 scopus 로고    scopus 로고
    • Anti-angiogenesis: Making the tumor vulnerable to the immune system
    • A.W. Griffioen Anti-angiogenesis: making the tumor vulnerable to the immune system Cancer Immunol. Immunother. 57 2008 1553 1558
    • (2008) Cancer Immunol. Immunother. , vol.57 , pp. 1553-1558
    • Griffioen, A.W.1
  • 25
    • 57949102533 scopus 로고    scopus 로고
    • Anti-angiogenic effects of rhubarb and its anthraquinone derivatives
    • Z.H. He, M.F. He, S.C. Ma, and P.P.H. But Anti-angiogenic effects of rhubarb and its anthraquinone derivatives J. Ethnopharmacol. 121 2009 313 317
    • (2009) J. Ethnopharmacol. , vol.121 , pp. 313-317
    • He, Z.H.1    He, M.F.2    Ma, S.C.3    But, P.P.H.4
  • 27
  • 28
    • 0035964450 scopus 로고    scopus 로고
    • Resveratrol and quercetin inhibit angiogenesis in vitro
    • DOI 10.1016/S0304-3835(01)00443-8, PII S0304383501004438
    • K. Igura, T. Ohta, Y. Kuroda, and K. Kaji Resveratrol and quercetin inhibit angiogenesis in vitro Cancer Lett. 171 2001 11 16 (Pubitemid 32727351)
    • (2001) Cancer Letters , vol.171 , Issue.1 , pp. 11-16
    • Igura, K.1    Ohta, T.2    Kuroda, Y.3    Kaji, K.4
  • 29
    • 55649088513 scopus 로고    scopus 로고
    • Recent advances in the investigation of curcuminoids
    • 10.1186/1749-8546-3-11
    • H. Itokawa, Q. Shi, T. Akiyama, S.L. Morris-Natschke, and K.H. Lee Recent advances in the investigation of curcuminoids Chin. Med. 3 II 2008 10.1186/1749-8546-3-11
    • (2008) Chin. Med. , vol.3 , Issue.2
    • Itokawa, H.1    Shi, Q.2    Akiyama, T.3    Morris-Natschke, S.L.4    Lee, K.H.5
  • 30
    • 0035682310 scopus 로고    scopus 로고
    • Inhibition of tumour invasion and angiogenesis by epigallocatechin gallate (EGCG), a major component of green tea
    • DOI 10.1046/j.1365-2613.2001.00205.x
    • Y.D. Jung, and L.M. Ellis Inhibition of tumour invasion and angiogenesis by epigallocatechin gallate (EGCG), a major component of green tea Int. J. Exp. Pathol. 82 2001 309 316 (Pubitemid 34063029)
    • (2001) International Journal of Experimental Pathology , vol.82 , Issue.6 , pp. 309-316
    • Jung, Y.D.1    Ellis, L.M.2
  • 31
    • 13744263516 scopus 로고    scopus 로고
    • Anti-angiogenic effects of SN38 (active metabolite of irinotecan): Inhibition of hypoxia-inducible factor 1 alpha HIF-1α/vascular endothelial growth factor (VEGF) expression of glioma and growth of endothelial cells
    • DOI 10.1007/s00432-004-0642-z
    • H. Kamiyama, S. Takano, K. Tsuboi, and A. Matsumura Anti-angiogenic effects of SN38 (active metabolite of irinotecan): inhibition of hypoxia-inducible factor 1 alpha (HIF-1alpha)/vascular endothelial growth factor (VEGF) expression of glioma and growth of endothelial cells J. Cancer Res. Clin. Oncol. 131 2005 205 213 (Pubitemid 40238935)
    • (2005) Journal of Cancer Research and Clinical Oncology , vol.131 , Issue.4 , pp. 205-213
    • Kamiyama, H.1    Takano, S.2    Tsuboi, K.3    Matsumura, A.4
  • 32
    • 60849126955 scopus 로고    scopus 로고
    • Inhibitory effects of Agaricus blazei extracts on human myeloid leukemia cells
    • C.F. Kim, J.J. Jiang, K.N. Leung, K.P. Fung, and B.S. Clara Lau Inhibitory effects of Agaricus blazei extracts on human myeloid leukemia cells J. Ethnopharmacol. 122 2009 320 326
    • (2009) J. Ethnopharmacol. , vol.122 , pp. 320-326
    • Kim, C.F.1    Jiang, J.J.2    Leung, K.N.3    Fung, K.P.4    Clara Lau, B.S.5
  • 33
    • 0034991938 scopus 로고    scopus 로고
    • Resveratrol isolated from Polygonum cuspidatum root prevents tumor growth and metastasis to lung and tumor-induced neovascularization in lewis lung carcinoma-bearing mice
    • Y. Kimura, and H. Okuda Resveratrol isolated from Polygonum cuspidatum root prevents tumor growth and metastasis to lung and tumor-induced neovascularization in Lewis lung carcinoma-bearing mice J. Nutr. 131 2001 1844 1849 (Pubitemid 32520456)
    • (2001) Journal of Nutrition , vol.131 , Issue.6 , pp. 1844-1849
    • Kimura, Y.1    Okuda, H.2
  • 34
    • 65549144056 scopus 로고    scopus 로고
    • Angiogenesis links chronic inflammation with cancer
    • H. Kobayashi, and P.C. Lin Angiogenesis links chronic inflammation with cancer Methods Mol. Biol. 511 2009 185 191
    • (2009) Methods Mol. Biol. , vol.511 , pp. 185-191
    • Kobayashi, H.1    Lin, P.C.2
  • 35
    • 2642544054 scopus 로고    scopus 로고
    • Geniposide, an anti-angiogenic compound from the fruits of Gardenia jasminoides
    • DOI 10.1055/s-2004-818978
    • H.J. Koo, S. Lee, K.H. Shin, B.C. Kim, C.J. Lim, and E.H. Park Geniposide, an antiangiogenic compound from the fruits of Gardenia jasminoides Planta Med. 70 2004 467 469 (Pubitemid 38716483)
    • (2004) Planta Medica , vol.70 , Issue.5 , pp. 467-469
    • Koo, H.-J.1    Lee, S.2    Shin, K.-H.3    Kim, B.-C.4    Lim, C.-J.5    Park, E.-H.6
  • 36
    • 51349137454 scopus 로고    scopus 로고
    • Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins
    • A.B. Kunnumakkara, P. Anand, and B.B. Aggarwal Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins Cancer Lett. 269 2008 199 225
    • (2008) Cancer Lett. , vol.269 , pp. 199-225
    • Kunnumakkara, A.B.1    Anand, P.2    Aggarwal, B.B.3
  • 38
    • 0036039827 scopus 로고    scopus 로고
    • In vivo imaging of embryonic vascular development using transgenic zebrafish
    • DOI 10.1006/dbio.2002.0711
    • N.D. Lawson, and B.M. Weinstein In vivo imaging of embryonic vascular development using transgenic zebrafish Dev. Biol. 248 2002 307 318 (Pubitemid 35002091)
    • (2002) Developmental Biology , vol.248 , Issue.2 , pp. 307-318
    • Lawson, N.D.1    Weinstein, B.M.2
  • 39
    • 33749558110 scopus 로고    scopus 로고
    • Potent inhibition of Lewis lung cancer growth by heyneanol A from the roots of Vitis amurensis through apoptotic and anti-angiogenic activities
    • DOI 10.1093/carcin/bgl055
    • E.O. Lee, H.J. Lee, H.S. Hwang, K.S. Ahn, C. Chae, K.S. Kang, J. Lu, and S.H. Kim Potent inhibition of Lewis lung cancer growth by heyneanol A from the roots of Vitis amurensis through apoptotic and anti-angiogenic activities Carcinogenesis 27 2006 2059 2069 (Pubitemid 44530581)
    • (2006) Carcinogenesis , vol.27 , Issue.10 , pp. 2059-2069
    • Lee, E.-O.1    Lee, H.-J.2    Hwang, H.-S.3    Ahn, K.-S.4    Chae, C.5    Kang, K.-S.6    Lu, J.7    Kim, S.-H.8
  • 40
    • 0035941166 scopus 로고    scopus 로고
    • Effects and mechanisms of aloe-emodin on cell death in human lung squamous cell carcinoma
    • H.Z. Lee, S.L. Hsu, M.C. Liu, and C.H. Wu Effects and mechanisms of aloe-emodin on cell death in human lung squamous cell carcinoma Eur. J. Pharmacol. 431 2001 287 295
    • (2001) Eur. J. Pharmacol. , vol.431 , pp. 287-295
    • Lee, H.Z.1    Hsu, S.L.2    Liu, M.C.3    Wu, C.H.4
  • 41
    • 67349249141 scopus 로고    scopus 로고
    • Rhein inhibits invasion and migration of human nasopharyngeal carcinoma cells in vitro by down-regulation of matrix metalloproteinases-9 and vascular endothelial growth factor
    • M.L. Lin, J.G. Chung, Y.C. Lu, C.Y. Yang, and S.S. Chen Rhein inhibits invasion and migration of human nasopharyngeal carcinoma cells in vitro by down-regulation of matrix metalloproteinases-9 and vascular endothelial growth factor Oral Oncol. 45 2009 531 537
    • (2009) Oral Oncol. , vol.45 , pp. 531-537
    • Lin, M.L.1    Chung, J.G.2    Lu, Y.C.3    Yang, C.Y.4    Chen, S.S.5
  • 42
    • 0043095357 scopus 로고    scopus 로고
    • Baicalein and baicalin are potent inhibitors of angiogenesis: Inhibition of endothelial cell proliferation, migration and differentiation
    • J.J. Liu, T.S. Huang, W.F. Cheng, and F.J. Lu Baicalein and baicalin are potent inhibitors of angiogenesis: inhibition of endothelial cell proliferation, migration and differentiation Int. J. Cancer 106 2003 559 565
    • (2003) Int. J. Cancer , vol.106 , pp. 559-565
    • Liu, J.J.1    Huang, T.S.2    Cheng, W.F.3    Lu, F.J.4
  • 44
    • 6944243800 scopus 로고    scopus 로고
    • Reduction of CWR22 prostate tumor xenograft growth by combined tamoxifen-quercetin treatment is associated with inhibition of angiogenesis and cellular proliferation
    • Z.S. Ma, T.H. Huynh, C.P. Ng, P.T. Do, T.H. Nguyen, and H. Huynh Reduction of CWR22 prostate tumor xenograft growth by combined tamoxifen-quercetin treatment is associated with inhibition of angiogenesis and cellular proliferation Int. J. Oncol. 24 2004 1297 1304
    • (2004) Int. J. Oncol. , vol.24 , pp. 1297-1304
    • Ma, Z.S.1    Huynh, T.H.2    Ng, C.P.3    Do, P.T.4    Nguyen, T.H.5    Huynh, H.6
  • 46
    • 41549108420 scopus 로고    scopus 로고
    • From single- to multi-target drugs in cancer therapy: When aspecificity becomes an advantage
    • DOI 10.2174/092986708783503212
    • A. Petrelli, and S. Giordano From single- to multi-target drugs in cancer therapy: when aspecificity becomes an advantage Curr. Med. Chem. 15 2008 422 432 (Pubitemid 351472408)
    • (2008) Current Medicinal Chemistry , vol.15 , Issue.5 , pp. 422-432
    • Petrelli, A.1    Giordano, S.2
  • 48
    • 35148848635 scopus 로고    scopus 로고
    • Anti-angiogenic therapies in cancer: Achievements and open questions
    • DOI 10.1684/bdc.2007.0451
    • C. Ruegg, and N. Mutter Anti-angiogenic therapies in cancer: achievements and open questions Bull. Cancer 94 2007 753 762 (Pubitemid 47605603)
    • (2007) Bulletin du Cancer , vol.94 , Issue.9 , pp. 753-762
    • Ruegg, C.1    Mutter, N.2
  • 54
    • 4544375253 scopus 로고    scopus 로고
    • Pseudolarix acid B inhibits angiogenesis by antagonizing the vascular endothelial growth factor-mediated anti-apoptotic effect
    • DOI 10.1016/j.ejphar.2004.07.063, PII S0014299904007964
    • W.F. Tan, X.W. Zhang, M.H. Li, J.M. Yue, Y. Chen, L.P. Lin, and J. Ding Pseudolarix acid B inhibits angiogenesis by antagonizing the vascular endothelial growth factor-mediated anti-apoptotic effect Eur. J. Pharmacol. 499 2004 219 228 (Pubitemid 39233660)
    • (2004) European Journal of Pharmacology , vol.499 , Issue.3 , pp. 219-228
    • Tan, W.-F.1    Zhang, X.-W.2    Li, M.-H.3    Yue, J.-M.4    Chen, Y.5    Lin, L.-P.6    Ding, J.7
  • 55
    • 0037303001 scopus 로고    scopus 로고
    • Recent development of antitumor agents from Chinese herbal medicines; part I. Low molecular compounds
    • DOI 10.1055/s-2003-37718
    • W. Tang, I. Hemm, and B. Bertram Recent development of antitumor agents from Chinese herbal medicines. Part I. Low molecular compounds Planta Med. 69 2003 97 108 (Pubitemid 36384491)
    • (2003) Planta Medica , vol.69 , Issue.2 , pp. 97-108
    • Tang, W.1    Hemm, I.2    Bertram, B.3
  • 56
    • 67650753834 scopus 로고    scopus 로고
    • The role of the Angiopoietins in vascular morphogenesis
    • M. Thomas, and H.G. Augustin The role of the Angiopoietins in vascular morphogenesis Angiogenesis 12 2009 125 137
    • (2009) Angiogenesis , vol.12 , pp. 125-137
    • Thomas, M.1    Augustin, H.G.2
  • 57
    • 0242405592 scopus 로고    scopus 로고
    • Role of Angiopoietins and Tie receptor tyrosine kinases in angiogenesis and lymphangiogenesis
    • DOI 10.1007/s00441-003-0749-6
    • G. Thurston Role of Angiopoietins and Tie receptor tyrosine kinases in angiogenesis and lymphangiogenesis Cell Tissue Res. 314 2003 61 68 (Pubitemid 37409913)
    • (2003) Cell and Tissue Research , vol.314 , Issue.1 , pp. 61-68
    • Thurston, G.1
  • 60
    • 0030806295 scopus 로고    scopus 로고
    • New nortriterpenoid isolated from anti-rheumatoid arthritic plant, Tripterygium wilfordii, modulates tumor growth and neovascularization
    • DOI 10.1002/(SICI)1097-0215(19970807)72:4<657::AID-IJC18>3.0.CO;2-8
    • S. Ushiro, M. Ono, J. Nakayama, T. Fujiwara, Y. Komatsu, K. Sugimachi, and M. Kuwano New nortriterpenoid isolated from anti-rheumatoid arthritic plant. Tripterygium wilfordii, modulates tumor growth and neovascularization Int. J. Cancer 72 1997 657 663 (Pubitemid 27356169)
    • (1997) International Journal of Cancer , vol.72 , Issue.4 , pp. 657-663
    • Ushiro, S.1    Ono, M.2    Nakayama, J.3    Fujiwara, T.4    Komatsu, Y.5    Sugimachi, K.6    Kuwano, M.7
  • 61
    • 0036775838 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase inhibitors of Chinese herbs III Rheum palmatum
    • C.C. Wang, Y.J. Huang, L.G. Chen, L.T. Lee, and L.L. Yang Inducible nitric oxide synthase inhibitors of Chinese herbs III Rheum palmatum Planta Med. 68 2002 869 874
    • (2002) Planta Med. , vol.68 , pp. 869-874
    • Wang, C.C.1    Huang, Y.J.2    Chen, L.G.3    Lee, L.T.4    Yang, L.L.5
  • 62
    • 4444273038 scopus 로고    scopus 로고
    • Inhibitory effects of emodin on angiogenesis
    • X.H. Wang, S.Y. Wu, and Y.S. Zhen Inhibitory effects of emodin on angiogenesis Yao Xue Xue Bao 39 2004 254 258
    • (2004) Yao Xue Xue Bao , vol.39 , pp. 254-258
    • Wang, X.H.1    Wu, S.Y.2    Zhen, Y.S.3
  • 63
    • 0344253733 scopus 로고    scopus 로고
    • Spatial Expression Patterns of Activin and Its Signaling System in the Zebrafish Ovarian Follicle: Evidence for Paracrine Action of Activin on the Oocytes
    • DOI 10.1095/biolreprod.103.020826
    • Y. Wang, and W. Ge Spatial expression patterns of activin and its signaling system in the zebrafish ovarian follicle: evidence for paracrine action of activin on the oocytes Biol. Reprod. 69 2003 1998 2006 (Pubitemid 37508491)
    • (2003) Biology of Reproduction , vol.69 , Issue.6 , pp. 1998-2006
    • Wang, Y.1    Ge, W.2
  • 65
    • 0036791813 scopus 로고    scopus 로고
    • Inhibitory effects of Ginkgo biloba extract on vascular endothelial growth factor in rat aortic endothelial cells
    • L. Zhang, Y.C. Rui, P.Y. Yang, Y. Qiu, T.J. Li, and H.C. Liu Inhibitory effects of Ginkgo biloba extract on vascular endothelial growth factor in rat aortic endothelial cells Acta Pharmacol. Sin. 23 2002 919 923
    • (2002) Acta Pharmacol. Sin. , vol.23 , pp. 919-923
    • Zhang, L.1    Rui, Y.C.2    Yang, P.Y.3    Qiu, Y.4    Li, T.J.5    Liu, H.C.6
  • 66
    • 33644618424 scopus 로고    scopus 로고
    • Antiangiogenic effect of low-dose cyclophosphamide combined with ginsenoside Rg3 on Lewis lung carcinoma
    • DOI 10.1016/j.bbrc.2006.02.044, PII S0006291X0600341X
    • Q. Zhang, X. Kang, and W. Zhao Antiangiogenic effect of low-dose cyclophosphamide combined with ginsenoside Rg3 on Lewis lung carcinoma Biochem. Biophys. Res. Commun. 342 2006 824 828 (Pubitemid 43320472)
    • (2006) Biochemical and Biophysical Research Communications , vol.342 , Issue.3 , pp. 824-828
    • Zhang, Q.1    Kang, X.2    Zhao, W.3
  • 67
    • 17844405853 scopus 로고    scopus 로고
    • Blockade of vascular endothelial growth factor receptor signal pathway and antitumor activity of ON-III (2′,4′-dihydroxy-6′-methoxy- 3′,5′-dimethylchalcone), a component from Chinese herbal medicine
    • X.F. Zhu, B.F. Xie, J.M. Zhou, G.K. Feng, Z.C. Liu, X.Y. Wei, F.X. Zhang, M.F. Liu, and Y.X. Zeng Blockade of vascular endothelial growth factor receptor signal pathway and antitumor activity of ON-III (2′,4′-dihydroxy- 6′-methoxy-3′,5′-dimethylchalcone), a component from Chinese herbal medicine Mol. Pharmacol. 67 2005 1444 1450
    • (2005) Mol. Pharmacol. , vol.67 , pp. 1444-1450
    • Zhu, X.F.1    Xie, B.F.2    Zhou, J.M.3    Feng, G.K.4    Liu, Z.C.5    Wei, X.Y.6    Zhang, F.X.7    Liu, M.F.8    Zeng, Y.X.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.