How broadly tuned olfactory receptors equally recognize their agonists. Human OR1G1 as a test case

Cellular and Molecular Life Sciences

Volumn 69, Issue 24, 2012, Pages 4205-4213

  Charlier, Landry ^a,e   Topin, Jérémie ^a   Ronin, Catherine ^b   Kim, Soo Kyung ^c   Goddard III, William A ^c   Efremov, Roman ^d   Golebiowski, Jérôme ^a  

^a UNIVERSITÉ DE NICE SOPHIA ANTIPOLIS   (France)

^b CNRS   (France)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^d SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^e UNIVERSITÉ DE MONTPELLIER   (France)

Author keywords

Free energy; GPCR; Molecular dynamics; Odorant; Structure

Indexed keywords

PROTEIN OR1G1; RECEPTOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; HYDROGEN BOND; MOLECULAR IMAGING; MOLECULAR MODEL; MOLECULAR RECOGNITION; OLFACTORY DISCRIMINATION; OLFACTORY RECEPTOR; PROTEIN STRUCTURE; RECEPTOR BINDING;

BINDING SITES; CALCIUM; HEK293 CELLS; HUMANS; LIGANDS; MODELS, BIOLOGICAL; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ODORANT; SMELL;

EID: 84870671969     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-012-1116-0     Document Type: Article

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