Combination chemotherapy using core-shell nanoparticles through the self-assembly of HPMA-based copolymers and degradable polyester

Journal of Controlled Release

Volumn 165, Issue 2, 2013, Pages 153-161

  Jäger, Eliézer ^a   Jäger, Alessandro ^a   Chytil, Petr ^a   Etrych, Tomáš ^a   Říhová, Blanka ^b   Giacomelli, Fernando Carlos ^c   Štěpánek, Petr ^a   Ulbrich, Karel ^a  

^a INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Czech Republic)

^b INSTITUTE OF MICROBIOLOGY   (Czech Republic)

^c UNIVERSIDADE FEDERAL DO ABC   (Brazil)

Author keywords

Combination therapy; Docetaxel; Doxorubicin; EL 4 T cell lymphoma in vivo; Polymeric core shell nanoparticles

Indexed keywords

COMBINATION THERAPY; CORE-SHELL NANOPARTICLES; DOCETAXEL; DOXORUBICIN; IN-VIVO;

BIODEGRADABLE POLYMERS; BUTENES; CHEMOTHERAPY; COPOLYMERS; DRUG DELIVERY; ONCOLOGY; SELF ASSEMBLY; SHELLS (STRUCTURES); TRANSMISSION ELECTRON MICROSCOPY; TUMORS;

NANOPARTICLES;

CHOLESTEROL; COPOLYMER; DOCETAXEL; DOXORUBICIN; N (2 HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER; NANOPARTICLE; POLY(BUTYLENE SUCCINATE CO BUTYLENE DILINOLEATE); POLYESTER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOCOMPATIBILITY; BIODEGRADATION; CANCER INHIBITION; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG POTENTIATION; DRUG STABILITY; HYDROPHOBICITY; LIGHT SCATTERING; MOUSE; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; T CELL LYMPHOMA; TRANSMISSION ELECTRON MICROSCOPY; TUMOR GROWTH;

ANIMALS; ANTINEOPLASTIC AGENTS; DOXORUBICIN; DRUG DELIVERY SYSTEMS; LYMPHOMA, T-CELL; METHACRYLATES; MICE; MICE, INBRED C57BL; MODELS, MOLECULAR; NANOPARTICLES; POLYESTERS; TAXOIDS;

EID: 84870670673     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.11.009     Document Type: Article

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