Selenium protects bone marrow stromal cells against hydrogen peroxide-induced inhibition of osteoblastic differentiation by suppressing oxidative stress and ERK signaling pathway

Biological Trace Element Research

Volumn 150, Issue 1-3, 2012, Pages 441-450

  Liu, Hongmei ^a,b   Bian, Weixia ^a   Liu, Songxiu ^a   Huang, Kaixun ^a,b  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Hubei Key Laboratory of Bioinorganic Chemistry and Materia Medica   (China)

Author keywords

Extracellular signal regulated kinase; Marrow stromal cells; Osteoblastic differentiation; Oxidative stress; Selenium

Indexed keywords

ALKALINE PHOSPHATASE; COLLAGEN TYPE 1; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; OSTEOCALCIN; SELENIUM; SODIUM SELENITE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; BONE MARROW CELL; BONE MATRIX; BONE REMODELING; CALCIFICATION; CELL DIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOPOROSIS; OXIDATIVE STRESS; PROTEIN FUNCTION; RAT; RISK FACTOR; SIGNAL TRANSDUCTION; SPINAL GANGLION; STROMA CELL;

ANIMALS; ANTIOXIDANTS; BIOLOGICAL MARKERS; CALCIFICATION, PHYSIOLOGIC; CELLS, CULTURED; DIETARY SUPPLEMENTS; HYDROGEN PEROXIDE; MALE; MAP KINASE SIGNALING SYSTEM; MESENCHYMAL STROMAL CELLS; OSTEOBLASTS; OSTEOCALCIN; OSTEOGENESIS; OSTEOPOROSIS; OXIDANTS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SELENIUM; SODIUM SELENITE;

RATTUS;

EID: 84870658484     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-012-9488-4     Document Type: Article

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