The need for a reassessment of the safe upper limit of selenium in drinking water

Science of the Total Environment

Volumn 443, Issue , 2013, Pages 633-642

  Vinceti, Marco ^a   Crespi, Catherine M ^b   Bonvicini, Francesca ^a,c   Malagoli, Carlotta ^a   Ferrante, Margherita ^d   Marmiroli, Sandra ^a   Stranges, Saverio ^e  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c PATHOLOGY UNIT   (Italy)

^d UNIVERSITY OF CATANIA   (Italy)

^e UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

Drinking water; Guideline; Human health; Risk assessment; Selenium; Standard

Indexed keywords

ANIMAL STUDIES; CHEMICAL FORMS; EPIDEMIOLOGIC-STUDY; EUROPEAN UNION; GUIDELINE; HEALTH EFFECTS; HUMAN HEALTH; HUMAN STUDY; HUMAN TOXICITY; IN-VITRO; LOW LEVEL; NUTRITIONAL PROPERTIES; ORGANIC SELENIUM COMPOUNDS; SELENIUM CONCENTRATIONS; UPPER LIMITS; WORLD HEALTH ORGANIZATION;

BIOACTIVITY; HEALTH; NUTRITION; POTABLE WATER; RISK ASSESSMENT; SELENIUM; STANDARDS; TOXICITY;

SELENIUM COMPOUNDS;

CARCINOGEN; DRINKING WATER; SELENATE; SELENITE; SELENIUM; SELENOMETHIONINE;

DRINKING WATER; EUROPEAN UNION; HEALTH IMPACT; HEALTH RISK; ORGANIC COMPOUND; RISK ASSESSMENT; SELENIUM; TOXICITY; TOXICOLOGY; WORLD HEALTH ORGANIZATION;

AIR POLLUTION; ARTICLE; CANCER MORTALITY; CANCER RISK; CARCINOGENICITY; CHRONIC DISEASE; ENVIRONMENTAL EXPOSURE; FOOD CONTAMINATION; HUMAN; IMMUNOTOXICITY; LONG TERM EXPOSURE; NONHUMAN; PRIORITY JOURNAL; REPRODUCTIVE TOXICITY; RISK ASSESSMENT; SAFE UPPER LIMIT; SOIL POLLUTION; TOXICITY TESTING; TOXICOKINETICS; TOXICOLOGICAL PARAMETERS; WATER CONTAMINATION; WATER QUALITY; WATER SUPPLY;

ANIMALS; DRINKING WATER; FEMALE; HUMANS; MICE; MICE, INBRED BALB C; SELENIUM;

EUROPE;

ANIMALIA;

EID: 84870655479     PISSN: 00489697     EISSN: 18791026     Source Type: Journal    
DOI: 10.1016/j.scitotenv.2012.11.025     Document Type: Article

References (162)

1. Aggett P.J. Toxicity due to excess and deficiency. J Toxicol Environ Health A 2010, 73:175-180.
2. Alexander J. Risk assessment of selenium. Scand J Work Environ Health 1993, 19(Suppl. 1):122-123.
3. Alfthan G., Wang D., Aro A., Soveri J. The geochemistry of selenium in groundwaters in Finland. Sci Total Environ 1992, 162:93-103.
4. Algotar AM, Stratton MS, Ahmann FR, Ranger-Moore J, Nagle RB, Thompson PA, et al. Phase 3 clinical trial investigating the effect of selenium supplementation in men at high-risk for prostate cancer. Prostate (in press).
5. Ammar E.M., Couri D. Acute toxicity of sodium selenite and selenomethionine in mice after ICV or IV administration. Neurotoxicology 1981, 2:383-386.
6. Anan Y., Tanabe S., Ogra Y. Comparison of selenoneine found in marine organisms with selenite in the interaction with mercury compounds in vitro. J Toxicol Sci 2011, 36:725-731.
7. Anonymous Selenium toxicity causes paralysis in Scottish pigs. Vet Rec 2010, 166:255-258.
8. Saisine n° 2011-SA-0220: Avis de l'Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail relatif à l'évaluation des risque sanitaires liés aux dépassement de la limite de qualité du sélénium dans les eaux destinées à la consommation humaine 2012, ANSES, Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail, Maisons-Alfort, France.
9. Arnaud J., de Lorgeril M., Akbaraly T., Salen P., Arnout J., Cappuccio F.P., et al. Gender differences in copper, zinc and selenium status in diabetic-free metabolic syndrome European population - the IMMIDIET study. Nutr Metab Cardiovasc Dis 2012, 22:517-524.
10. Ayaz M., Dalkilic N., Tuncer S., Bariskaner H. Selenium-induced changes on rat sciatic nerve fibers: compound action potentials. Methods Find Exp Clin Pharmacol 2008, 30:271-275.
11. Balansky R.M., De Flora S. Interactions between N-acetylcysteine and sodium selenite in modulating the clastogenicity of urethane and 2-acetylaminofluorene in mice. Int J Cancer 2004, 108:158-161.
12. Barbosa N.B., Rocha J.B., Zeni G., Emanuelli T., Beque M.C., Braga A.L. Effect of organic forms of selenium on delta-aminolevulinate dehydratase from liver, kidney, and brain of adult rats. Toxicol Appl Pharmacol 1998, 149:243-253.
13. Barron E., Migeot V., Rabouan S., Potin-Gautier M., Seby F., Hartemann P., et al. The case for re-evaluating the upper limit value for selenium in drinking water in Europe. J Water Health 2009, 7:630-641.
14. Barron E., Migeot V., Seby F., Ingrand I., Potin-Gautier M., Legube B., et al. Selenium exposure in subjects living in areas with high selenium concentrated drinking water: results of a French integrated exposure assessment survey. Environ Int 2012, 40:155-161.
15. Bergomi M., Malagoli C., Vinceti M. Selenium deficiency. Encyclopedia of molecular mechanisms of disease 2009, 1914-1915. Springer-Verlag, Berlin. F. Lang (Ed.).
16. Bergomi M., Malagoli C., Vinceti M. Selenium excess. Encyclopedia of molecular mechanisms of disease 2009, 1915-1916. Springer-Verlag, Berlin. F. Lang (Ed.).
17. Berthold H.K., Michalke B., Krone W., Guallar E., Gouni-Berthold I. Influence of serum selenium concentrations on hypertension: the Lipid Analytic Cologne cross-sectional study. J Hypertens 2012, 30:1328-1335.
18. Bleys J., Navas-Acien A., Stranges S., Menke A., Miller E.R., Guallar E. Serum selenium and serum lipids in US adults. Am J Clin Nutr 2008, 88:416-423.
19. Borella P., Bargellini A., Medici C.I. Chemical form of selenium greatly affects metal uptake and responses by cultured human lymphocytes. Biol Trace Elem Res 1996, 51:43-54.
20. Brandao R., de Oliveira R., Nogueira C.W. Association between diphenyl diselenide and cadmium chloride attenuates the toxicity of both in tissues of mice in vitro. Toxicol In Vitro 2010, 24:1736-1742.
21. Brandao R., Moresco R.N., Belle L.P., Leite M.R., de Freitas M.L., Bianchini A., et al. Diphenyl diselenide potentiates nephrotoxicity induced by mercuric chloride in mice. J Appl Toxicol 2011, 31:773-782.
22. Brätter P., Negretti de Brätter V.E. Influence of high dietary intake on the thyroid hormone level in human serum. J Trace Elem Med Biol 1996, 10:163-166.
23. Bronzetti G., Cini M., Andreoli E., Caltavuturo L., Panunzio M., Croce C.D. Protective effects of vitamins and selenium compounds in yeast. Mutat Res 2001, 496:105-115.
24. Brozmanova J., Manikova D., Vlckova V., Chovanec M. Selenium: a double-edged sword for defense and offence in cancer. Arch Toxicol 2010, 84:919-938.
25. Brtko J., Filipcik P. Effect of selenite and selenate on rat liver nuclear 3,5,3'-triiodothyronine (T3) receptor. Biol Trace Elem Res 1994, 41:191-199.
26. Brtko J., Filipcik P., Hudecova S., Brtkova A., Bransova J. Nuclear all-trans retinoic acid receptors: in vitro effects of selenium. Biol Trace Elem Res 1998, 62:43-50.
27. Bruhn R.L., Stamer W.D., Herrygers L.A., Levine J.M., Noecker R.J. Relationship between glaucoma and selenium levels in plasma and aqueous humour. Br J Ophthalmol 2009, 93:1155-1158.
28. Casteignau A., Fontan A., Morillo A., Oliveros J.A., Segales J. Clinical, pathological and toxicological findings of a iatrogenic selenium toxicosis case in feeder pigs. J Vet Med A Physiol Pathol Clin Med 2006, 53:323-326.
29. Cemeli E., Marcos R., Anderson D. Genotoxic and antigenotoxic properties of selenium compounds in the in vitro micronucleus assay with human whole blood lymphocytes and TK6 lymphoblastoid cells. Sci World J 2006, 6:1202-1210.
30. Chandra R.K., Hambreaus L., Puri S., Au B., Kutty K.M. Immune response of healthy volunteers given supplements of zinc or selenium. FASEB J 1993, A23.
31. Chatterjee M., Banerjee M.R. Selenium mediated dose-inhibition of 7,12-dimethylbenz[a] anthracene-induced transformation of mammary cells in organ culture. Cancer Lett 1982, 17:187-195.
32. Clark L.C., Combs G.F.J., Turnbull B.W., Slate E.H., Chalker D.K., Chow J., et al. Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial. Nutritional Prevention of Cancer Study Group. JAMA 1996, 276:1957-1963.
33. Combs G.F. Selenium in global food systems. Br J Nutr 2001, 85:517-547.
34. Conde J.E., Sanz Alaejos M. Selenium concentrations in natural and environmental waters. Chem Rev 1997, 97:1979-2004.
35. Copat C., Maggiore R., Arena G., Lanzafame S., Fallico R., Sciacca S., et al. Evaluation of a temporal trend heavy metals contamination in Posidonia oceanica (L.) Delile, (1813) along the western coastline of Sicily (Italy). J Environ Monit 2012, 14:187-192.
36. Dennert G., Zwahlen M., Brinkman M., Vinceti M., Zeegers M.P., Horneber M. Selenium for preventing cancer. Cochrane Database Syst Rev 2011, 5:CD005195.
37. Dhillon K.S., Dhillon S.K. Quality of underground water and its contribution towards selenium enrichment of the soil-plant system for a seleniferous region of northwest India. J Hydrol 2003, 272:120-130.
38. Doering P., Stoltenberg M., Penkowa M., Rungby J., Larsen A., Danscher G. Chemical blocking of zinc ions in CNS increases neuronal damage following traumatic brain injury (TBI) in mice. PLoS One 2010, 5:e10131.
39. Dougherty J.J., Hoekstra W.G. Stimulation of lipid peroxidation in vivo by injected selenite and lack of stimulation by selenate. Proc Soc Exp Biol Med 1982, 169:209-215.
40. Douron M. U-shaped dose-response curves: implications for risk characterization of essential elements and other chemicals. J Toxicol Environ Health A 2010, 73:181-186.
41. Duffield-Lillico A.J., Reid M.E., Turnbull B.W., Combs G.F.J., Slate E.H., Fischbach L.A., et al. Baseline characteristics and the effect of selenium supplementation on cancer incidence in a randomized clinical trial: a summary report of the Nutritional Prevention of Cancer Trial. Cancer Epidemiol Biomarkers Prev 2002, 11:630-639.
42. Duffield-Lillico A.J., Slate E.H., Reid M.E., Turnbull B.W., Wilkins P.A., Combs G.F., et al. Selenium supplementation and secondary prevention of nonmelanoma skin cancer in a randomized trial. J Natl Cancer Inst 2003, 95:1477-1481.
43. El-Demerdash F.M. Effects of selenium and mercury on the enzymatic activities and lipid peroxidation in brain, liver, and blood of rats. J Environ Sci Health B 2001, 36:489-499.
44. European Council Council Directive 98/83/EC of 3 November 1998 on the quality of water intended for human consumption. Off J Eur Union 1998, 330:32-54.
45. Ezzedine K., Latreille J., Kesse-Guyot E., Galan P., Hercberg S., Guinot C., et al. Incidence of skin cancers during 5-year follow-up after stopping antioxidant vitamins and mineral supplementation. Eur J Cancer 2010, 46:3316-3322.
46. Fan A.M., Kizer K.W. Selenium. Nutritional, toxicologic, and clinical aspects. West J Med 1990, 153:160-167.
47. Ferri T., Frasconi M. Determination of Se(IV) and Se(VI) in Italian mineral waters. Ann Chim 2006, 96:647-656.
48. Fordyce F. Selenium deficiency and toxicity in the environment. Essentials of medical geology 2005, Elsevier, Amsterdam. O. Selinus (Ed.).
49. Fordyce F. Selenium geochemistry and health. Ambio 2007, 36:94-97.
50. Frouin H., Loseto L.L., Stern G.A., Haulena M., Ross P.S. Mercury toxicity in beluga whale lymphocytes: limited effects of selenium protection. Aquat Toxicol 2011, 109:185-193.
51. Gabel-Jensen C., Lunoe K., Gammelgaard B. Formation of methylselenol, dimethylselenide and dimethyldiselenide in in vitro metabolism models determined by headspace GC-MS. Metallomics 2010, 2:167-173.
52. Gammelgaard B., Rasmussen L.H., Gabel-Jensen C., Steffansen B. Estimating intestinal absorption of inorganic and organic selenium compounds by in vitro flux and biotransformation studies in Caco-2 cells and ICP-MS detection. Biol Trace Elem Res 2012, 145:248-256.
53. Gao S., Tanji K.K., Dahlgren R.A., Ryu J., Herbel M.J., Higashi R.M. Chemical status of selenium in evaporation basins for disposal of agricultural drainage. Chemosphere 2007, 69:585-594.
54. Ghosh J. Rapid induction of apoptosis in prostate cancer cells by selenium: reversal by metabolites of arachidonate 5-lipoxygenase. Biochem Biophys Res Commun 2004, 315:624-635.
55. Gilron G. The selenium drinking water quality guideline in Canada: the case for a re-evaluation. Integr Environ Assess Manag 2012, 8:194-196.
56. Glaser V., Nazari E.M., Muller Y.M., Feksa L., Wannmacher C.M., Rocha J.B., et al. Effects of inorganic selenium administration in methylmercury-induced neurotoxicity in mouse cerebral cortex. Int J Dev Neurosci 2010, 28:631-637.
57. Gore F., Fawell J., Bartram J. Too much or too little? A review of the conundrum of selenium. J Water Health 2010, 8:405-416.
58. Gourcy L., Lions J., Garnier C. Understanding natural occurrence and time variation of selenium in drinking water in the Paris Basin. Proceedings of the SEGH International Conference 2010, Society for Environmental Geochemistry and Health, Galway.
59. Hammer M.J. An assessment of current standards for selenium in drinking water. Ground Water 1981, 19:366-369.
60. Heinz G.H., Hoffman D.J., Klimstra J.D., Stebbins K.R. A comparison of the teratogenicity of methylmercury and selenomethionine injected into bird eggs. Arch Environ Contam Toxicol 2012, 62:519-528.
61. Hercberg S., Ezzedine K., Guinot C., Preziosi P., Galan P., Bertrais S., et al. Antioxidant supplementation increases the risk of skin cancers in women but not in men. J Nutr 2007, 137:2098-2105.
62. Holm J., Palace V., Siwik P., Sterling G., Evans R., Baron C., et al. Developmental effects of bioaccumulated selenium in eggs and larvae of two salmonid species. Environ Toxicol Chem 2005, 24:2373-2381.
63. Hu X., Wang F., Hanson M.L. Selenium concentration, speciation and behavior in surface waters of the Canadian prairies. Sci Total Environ 2009, 407:5869-5876.
64. Hudak P.F. Elevated fluoride and selenium in west Texas groundwater. Bull Environ Contam Toxicol 2009, 82:39-42.
65. Hurtado-Jimenez R., Gardea-Torresdey J. Evaluation of the exposure to selenium in Los Altos de Jalisco, Mexico. Salud Publica Mex 2007, 49:312-315.
66. ICAIR - Life Systems Inc Drinking Water Criteria Document for Selenium, Draft Report. TR-1242-65, NTIS PB91-142828 1990, Criteria and Standards Division, Office of Drinking Water, United States Environmental Protection Agency, Washington, DC.
67. IPCS INCHEM Environmental Health Criteria 58. Selenium 1987, World Health Organization, Geneva, Switzerland.
68. Johnson V.J., Tsunoda M., Sharma R.P. Increased production of proinflammatory cytokines by murine macrophages following oral exposure to sodium selenite but not to seleno-L-methionine. Arch Environ Contam Toxicol 2000, 39:243-250.
69. Kandas N.O., Randolph C., Bosland M.C. Differential effects of selenium on benign and malignant prostate epithelial cells: stimulation of LNCaP cell growth by noncytotoxic, low selenite concentrations. Nutr Cancer 2009, 61:251-264.
70. Kilness A.W., Hochberg F.H. Amyotrophic lateral sclerosis in a high selenium environment. JAMA 1977, 237:2843-2844.
71. Kim Y.Y., Mahan D.C. Comparative effects of high dietary levels of organic and inorganic selenium on selenium toxicity of growing-finishing pigs. J Anim Sci 2001, 79:942-948.
72. Klein E.A., Thompson I.M., Tangen C.M., Crowley J.J., Lucia M.S., Goodman P.J., et al. Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA 2011, 306:1549-1556.
73. Krogh V., Pala V., Vinceti M., Berrino F., Ganzi A., Micheli A., et al. Toenail selenium as biomarker: reproducibility over a one-year period and factors influencing reproducibility. J Trace Elem Med Biol 2003, 17(Suppl. 1):31-36.
74. Kuisi M.A., Abdel-Fattah A. Groundwater vulnerability to selenium in semi-arid environments: Amman Zarqa Basin, Jordan. Environ Geochem Health 2010, 32:107-128.
75. Kumar A.R., Riyazuddin P. Speciation of selenium in groundwater: seasonal variations and redox transformations. J Hazard Mater 2011, 192:263-269.
76. Laclaustra M., Navas-Acien A., Stranges S., Ordovas J.M., Guallar E. Serum selenium concentrations and diabetes in U.S. adults: National Health and Nutrition Examination Survey (NHANES) 2003-2004. Environ Health Perspect 2009, 117:1409-1413.
77. Laclaustra M., Stranges S., Navas-Acien A., Ordovas J.M., Guallar E. Serum selenium and serum lipids in US adults: National Health and Nutrition Examination Survey (NHANES) 2003-2004. Atherosclerosis 2010, 210:643-648.
78. Lafond M.G., Calabrese E.J. Is the selenium drinking water standard justified?. Med Hypotheses 1979, 5:877-899.
79. Lahermo P., Alfthan G., Wang D. Selenium and arsenic in the environment in Finland. J Environ Pathol Toxicol Oncol 1998, 17:205-216.
80. Lee K.H., Jeong D. Bimodal actions of selenium essential for antioxidant and toxic pro-oxidant activities: the selenium paradox (Review). Mol Med Report 2012, 5:299-304.
81. Lemire M., Fillion M., Frenette B., Passos C.J., Guimaraes J.R., Barbosa F., et al. Selenium from dietary sources and motor functions in the Brazilian Amazon. Neurotoxicology 2011, 32:944-953.
82. Levander O.A. Selenium requirements as discussed in the 1996 joint FAO/IAEA/WHO expert consultation on trace elements in human nutrition. Biomed Environ Sci 1997, 10:214-219.
83. Lillico A., Jacobs E., Reid M.E. Selenium supplementations and risk of glaucoma in the NPC trial 2002, University of Arizona, Tucson, AZ.
84. Lippman S.M., Klein E.A., Goodman P.J., Lucia M.S., Thompson I.M., Ford L.G., et al. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA 2009, 301:39-51.
85. Macallan D.C., Sedgwick P. Selenium supplementation and selenoenzyme activity. Clin Sci 2000, 99:579-581.
86. Mao X, Yuan S, Fallahpour N, Ciblak A, Howard J, Padilla I, et al. Electrochemically Induced Dual Reactive Barriers for Transformation of TCE and Mixture of Contaminants in Groundwater. Environ Sci Technol (in press).
87. Maraldi T., Riccio M., Zambonin L., Vinceti M., De Pol A., Hakim G. Low levels of selenium compounds are selectively toxic for a human neuron cell line through ROS/RNS increase and apoptotic process activation. Neurotoxicology 2011, 32:180-187.
88. Marshall J.R., Reid M.E., Lillico A. Nutritional prevention of cancer: review of glaucoma data 2002, University of Arizona, Tucson, AZ.
89. Medeiros M.C., Mello A., Gemelli T., Teixeira C., de Almeida M., de Andrade R.B., et al. Effect of chronic administration of the vinyl chalcogenide 3-methyl-1-phenyl-2-(phenylseleno)oct-2-en-1-one on oxidative stress in different brain areas of rats. Neurochem Res 2012, 37:928-934.
90. Methenitou G., Maravelias C., Athanaselis S., Dona A., Koutselinis A. Immunomodulative effects of aflatoxins and selenium on human natural killer cells. Vet Hum Toxicol 2001, 43:232-234.
91. Michalke B., Halbach S., Nischwitz V. JEM spotlight: metal speciation related to neurotoxicity in humans. J Environ Monit 2009, 11:939-954.
92. Miller L.L., Hontela A. Species-specific sensitivity to selenium-induced impairment of cortisol secretion in adrenocortical cells of rainbow trout (Oncorhynchus mykiss) and brook trout (Salvelinus fontinalis). Toxicol Appl Pharmacol 2011, 253:137-144.
93. Nair M.P., Schwartz S.A. Immunoregulation of natural and lymphokine-activated killer cells by selenium. Immunopharmacology 1990, 19:177-183.
94. National Toxicology Program Selenium sulfide. Rep Carcinog 2002, 10:214-215.
95. National Toxicology Program Selenium sulfide. Rep Carcinog 2011, 12:376-377.
96. Navarro-Alarcon M., Cabrera-Vique C. Selenium in food and the human body: a review. Sci Total Environ 2008, 400:115-141.
97. Nogueira C.W., Rocha J.B. Toxicology and pharmacology of selenium: emphasis on synthetic organoselenium compounds. Arch Toxicol 2011, 85:1313-1359.
98. Novoselov S.V., Calvisi D.F., Labunskyy V.M., Factor V.M., Carlson B.A., Fomenko D.E., et al. Selenoprotein deficiency and high levels of selenium compounds can effectively inhibit hepatocarcinogenesis in transgenic mice. Oncogene 2005, 24:8003-8011.
99. OEHHA Public Health Goal for selenium in drinking water 2010, Office of Environmental Health Hazard Assessment, California Environmental Protection Agency, Oakland, http://oehha.ca.gov/water/phg/pdf/SeleniumPHG121010.pdf.
100. Panter K.E., Hartley W.J., James L.F., Mayland H.F., Stegelmeier B.L., Kechele P.O. Comparative toxicity of selenium from seleno-DL-methionine, sodium selenate, and Astragalus bisulcatus in pigs. Fundam Appl Toxicol 1996, 32:217-223.
101. Park K., Rimm E.B., Siscovick D.S., Spiegelman D., Manson J.E., Morris J.S., et al. Toenail selenium and incidence of type 2 diabetes mellitus in U.S. men and women. Diabetes Care 2012, 35:1544-1551.
102. Pinto A., Speckmann B., Heisler M., Sies H., Steinbrenner H. Delaying of insulin signal transduction in skeletal muscle cells by selenium compounds. J Inorg Biochem 2011, 105:812-820.
103. Pletnikova I.P. Biological effect and level of safety of selenium in its entry into the organism with drinking water. Gig Sanit 1970, 35:14-19.
104. Preud'homme H., Far J., Gil-Casal S., Lobinski R. Large-scale identification of selenium metabolites by online size-exclusion-reversed phase liquid chromatography with combined inductively coupled plasma (ICP-MS) and electrospray ionization linear trap-Orbitrap mass spectrometry (ESI-MS(n)). Metallomics 2012, 4:422-432.
105. Raber M., Sydler T., Wolfisberg U., Geyer H., Burgi E. Feed-related selenium poisoning in swine. Schweiz Arch Tierheilkd 2010, 152:245-252.
106. Raines A.M., Sunde R.A. Selenium toxicity but not deficient or super-nutritional selenium status vastly alters the transcriptome in rodents. BMC Genomics 2011, 12:26.
107. Randhawa N.S., Das N.N., Jana R.K. Selenite adsorption using leached residues generated by reduction roasting-ammonia leaching of manganese nodules. J Hazard Mater 2012, 241-242:486-492.
108. Ravn-Haren G., Krath B.N., Overvad K., Cold S., Moesgaard S., Larsen E.H., et al. Effect of long-term selenium yeast intervention on activity and gene expression of antioxidant and xenobiotic metabolising enzymes in healthy elderly volunteers from the Danish Prevention of Cancer by Intervention by Selenium (PRECISE) pilot study. Br J Nutr 2008, 99:1190-1198.
109. Renwick A.G., Walker R. Risk assessment of micronutrients. Toxicol Lett 2008, 180:123-130.
110. Ritter L., Totman C., Krishnan K., Carrier R., Vezina A., Morisset V. Deriving uncertainty factors for threshold chemical contaminants in drinking water. J Toxicol Environ Health B Crit Rev 2007, 10:527-557.
111. Rotruck J.T., Pope A.L., Ganther H.E., Swanson A.B., Hafeman D.G., Hoekstra W.G. Selenium: biochemical role as a component of glutathione peroxidase. Science 1973, 179:588-590.
112. Saint-Amour D., Roy M.S., Bastien C., Ayotte P., Dewailly E., Despres C., et al. Alterations of visual evoked potentials in preschool Inuit children exposed to methylmercury and polychlorinated biphenyls from a marine diet. Neurotoxicology 2006, 27:567-578.
113. Smith M.I., Westfall B.B. The selenium problem in relation to public health. Public Health Rep 1936, 51:1496-1505.
114. Smith M.I., Westfall B.B. Further field studies on the selenium problem in relation to public health. Public Health Rep 1937, 52:1375-1384.
115. Solovyev N, Berthele A, Michalke B. Selenium speciation in paired serum and cerebrospinal fluid samples. Anal Bioanal Chem (in press).
116. Soudani N., Troudi A., Bouaziz H., Ben Amara I., Boudawara T., Zeghal N. Cardioprotective effects of selenium on chromium (VI)-induced toxicity in female rats. Ecotoxicol Environ Saf 2011, 74:513-520.
117. Stepnik M., Stetkiewicz J., Krajnow A., Domeradzka K., Gradecka-Meesters D., Arkusz J., et al. Carcinogenic effect of arsenate in C57BL/6J/Han mice and its modulation by different dietary selenium status. Ecotoxicol Environ Saf 2009, 72:2143-2152.
118. Stoica A., Pentecost E., Martin M.B. Effects of selenite on estrogen receptor-alpha expression and activity in MCF-7 breast cancer cells. J Cell Biochem 2000, 79:282-292.
119. Stranges S., Marshall J.R., Natarajan R., Donahue R.P., Trevisan M., Combs G.F., et al. Effects of long-term selenium supplementation on the incidence of type 2 diabetes: a randomized trial. Ann Intern Med 2007, 147:217-223.
120. Stranges S., Navas-Acien A., Rayman M.P., Guallar E. Selenium status and cardiometabolic health: state of the evidence. Nutr Metab Cardiovasc Dis 2010, 20:754-760.
121. Stranges S., Sieri S., Vinceti M., Grioni S., Guallar E., Laclaustra M., et al. A prospective study of dietary selenium intake and risk of type 2 diabetes. BMC Public Health 2010, 10:564.
122. Su Y.P., Tang J.M., Tang Y., Gao H.Y. Histological and ultrastructural changes induced by selenium in early experimental gastric carcinogenesis. World J Gastroenterol 2005, 11:4457-4460.
123. Suadicani P., Hein H.O., Gyntelberg F. Serum selenium level and risk of lung cancer mortality: a 16-year follow-up of the Copenhagen Male Study. Eur Respir J 2012, 39:1443-1448.
124. Thomas D.C. Statistical methods in environmental epidemiology 2009, Oxford University Press, New York.
125. Tsongas T.A., Ferguson S.W. Human health effects of selenium in a rural Colorado drinking water supply. Proceedings of "Trace substances in environmental health-XI. A symposium" 1977, 30-35. University of Missouri, Columbia. D.D. Hemphill (Ed.).
126. Tsongas T.A., Ferguson S.W. Selenium concentrations in human urine and drinking water. Proceedings of "Trace Elements in Man and Animal-3" 1978, 320-321. N. Kirchgessner (Ed.).
127. Tsunoda M., Johnson V.J., Sharma R.P. Increase in dopamine metabolites in murine striatum after oral exposure to inorganic but not organic form of selenium. Arch Environ Contam Toxicol 2000, 39:32-37.
128. United States Environmental Protection Agency Selenium sulfide quickview (CASRN 7446-34-6) - carcinogenicity assessment for lifetime exposure (weight-of-evidence characterization) http://water.epa.gov/drink/standardsriskmanagement.cfm.
129. United States Environmental Protection Agency WaterDrinking WaterStandards & Risk Management http://water.epa.gov/drink/standardsriskmanagement.cfm.
130. Usami M., Ohno Y. Teratogenic effects of selenium compounds on cultured postimplantation rat embryos. Teratog Carcinog Mutagen 1996, 16:27-36.
131. Usami M., Mitsunaga K., Nakazawa K., Doi O. Proteomic analysis of selenium embryotoxicity in cultured postimplantation rat embryos. Birth Defects Res B Dev Reprod Toxicol 2008, 83:80-96.
132. Valdiglesias V., Pasaro E., Mendez J., Laffon B. In vitro evaluation of selenium genotoxic, cytotoxic, and protective effects: a review. Arch Toxicol 2010, 84:337-351.
133. Valentine J.L. Environmental occurrence of selenium in waters and related health significance. Biomed Environ Sci 1997, 10:292-299.
134. Valentine J.L., Kang H.K., Dang P.M., Schluchter M. Selenium concentrations and glutathione peroxidase activities in a population exposed to selenium via drinking water. J Toxicol Environ Health 1980, 6:731-736.
135. Valentine J.L., Reisbord L.S., Kang H.K., Schluchter M. Effects on human health of exposure to selenium in drinking water. Proceedings of "Selenium in Biology and Medicine - Part B" 1987, 675-687. Van Nostrand Reihold Co, New York. G.F. Combs, O.A. Levander, J.E. Spallholz, J.E. Oldfield (Eds.).
136. Valentine J.L., Faraji B., Kang H.K. Human glutathione peroxidase activity in cases of high selenium exposures. Environ Res 1988, 45:16-27.
137. van Woudenbergh G.J., van Ballegooijen A.J., Kuijsten A., Sijbrands E.J., van Rooij F.J., Geleijnse J.M., et al. Eating fish and risk of type 2 diabetes: a population-based, prospective follow-up study. Diabetes Care 2009, 32:2021-2026.
138. Vernie L.N., De Vries M., Karreman L., Topp R.J., Bont W.S. Inhibition of amino acid incorporation in a cell-free system and inhibition of protein synthesis in cultured cells by reaction products of selenite and thiols. Biochim Biophys Acta 1983, 739:1-7.
139. Vinceti M., Rovesti S., Marchesi C., Bergomi M., Vivoli G. Changes in drinking water selenium and mortality for coronary disease in a residential cohort. Biol Trace Elem Res 1994, 40:267-275.
140. Vinceti M., Rovesti S., Gabrielli C., Marchesi C., Bergomi M., Martini M., et al. Cancer mortality in a residential cohort exposed to environmental selenium through drinking water. J Clin Epidemiol 1995, 48:1091-1097.
141. Vinceti M., Guidetti D., Pinotti M., Rovesti S., Merlin M., Vescovi L., et al. Amyotrophic lateral sclerosis after long-term exposure to drinking water with high selenium content. Epidemiology 1996, 7:529-532.
142. Vinceti M., Guidetti D., Bergomi M., Caselgrandi E., Vivoli R., Olmi M., et al. Lead, cadmium, and selenium in the blood of patients with sporadic amyotrophic lateral sclerosis. Ital J Neurol Sci 1997, 18:87-92.
143. Vinceti M., Rothman K.J., Bergomi M., Borciani N., Serra L., Vivoli G. Excess melanoma incidence in a cohort exposed to high levels of environmental selenium. Cancer Epidemiol Biomarkers Prev 1998, 7:853-856.
144. Vinceti M., Cann C.I., Calzolari E., Vivoli R., Garavelli L., Bergomi M. Reproductive outcomes in a population exposed long-term to inorganic selenium via drinking water. Sci Total Environ 2000, 250:1-7.
145. Vinceti M., Nacci G., Rocchi E., Cassinadri T., Vivoli R., Marchesi C., et al. Mortality in a population with long-term exposure to inorganic selenium via drinking water. J Clin Epidemiol 2000, 53:1062-1068.
146. Vinceti M., Rovesti S., Bergomi M., Vivoli G. The epidemiology of selenium and human cancer. Tumori 2000, 86:105-118.
147. Vinceti M., Wei E.T., Malagoli C., Bergomi M., Vivoli G. Adverse health effects of selenium in humans. Rev Environ Health 2001, 16:233-251.
148. Vinceti M., Maraldi T., Bergomi M., Malagoli C. Risk of chronic low-dose selenium overexposure in humans: insights from epidemiology and biochemistry. Rev Environ Health 2009, 24:231-248.
149. Vinceti M., Bonvicini F., Rothman K.J., Vescovi L., Wang F. The relation between amyotrophic lateral sclerosis and inorganic selenium in drinking water: a population-based case-control study. Environ Health 2010, 9:77.
150. Vinceti M., Bottecchi I., Fan A., Finkelstein Y., Mandrioli J. Are environmental exposures to selenium, heavy metals and pesticides risk factors for amyotrophic lateral sclerosis?. Rev Environ Health 2012, 27:19-41.
151. Vinceti M., Crespi C.M., Malagoli C., Bottecchi E., Ferrari A., Sieri S., et al. A case-control study of the risk of cutaneous melanoma associated with three selenium exposure indicators. Tumori 2012, 98:287-295.
152. Vinson J.A., Bose P. Comparison of the toxicity of inorganic and natural selenium. Proceedings of "Selenium in Biology and Medicine" symposium 1987, 513-515. AVI Publisher. G.F. Combs, J.E. Spallholz, O.A. Levander, J.E. Oldfield (Eds.).
153. Wallschlager D., Feldmann J. Formation, occurrence, significance, and analysis of organoselenium and organotellurium compounds in the environment. Met Ions Life Sci 2010, 7:319-364.
154. Wang D., Alfthan G., Aro A., Keuppi L., Soveri J. Selenium in tap water and natural water ecosystem in Finland. Trace Elements in Health and Disease 1991, 49-56. Royal Society of Chemistry, London. A. Aitio, A. Aro, J. Järvisalo (Eds.).
155. WHO Guidelines for drinking water quality. Health criteria and other supporting information-2nd ed. 1996, 2. World Health Organization, Geneva, Switzerland.
156. WHO Selenium in drinking-water. Background document for preparation of WHO Guidelines for drinking-water quality. WHO/SDE/WSH/03.04/13/Rev/1 2011, World Health Organization, Geneva, Switzerland.
157. WHO Guidelines for drinking-water quality 2011, World Health Organization, Geneva, Switzerland. 4th ed.
158. Willhite C.C. Selenium teratogenesis. Species-dependent response and influence on reproduction. Ann N Y Acad Sci 1993, 678:169-177.
159. Wu L. Review of 15 years of research on ecotoxicology and remediation of land contaminated by agricultural drainage sediment rich in selenium. Ecotoxicol Environ Saf 2004, 57:257-269.
160. Xiao R., Qiao J.T., Zhao H.F., Liang J., Yu H.L., Liu J., et al. Sodium selenite induces apoptosis in cultured cortical neurons with special concomitant changes in expression of the apoptosis-related genes. Neurotoxicology 2006, 27:478-484.
161. Yanardag R., Orak H. Total selenium concentrations in various waters of Turkey. Environ Technol 2001, 22:237-246.
162. Zwolak I., Zaporowska H. Selenium interactions and toxicity: a review: selenium interactions and toxicity. Cell Biol Toxicol 2012, 28:31-46.