Adult Cardiac Progenitor Cell Aggregates Exhibit Survival Benefit Both In Vitro and In Vivo

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Bauer, Michael ^a   Kang, Lifeng ^a,b,c   Qiu, Yiling ^a   Wu, Jinhui ^a,b,d   Peng, Michelle ^a,b   Chen, Howard H ^e   Camci Unal, Gulden ^a,b   Bayomy, Ahmad F ^a,f   Sosnovik, David E ^b,e   Khademhosseini, Ali ^a,b,g   Liao, Ronglih ^a,h  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d NANJING UNIVERSITY   (China)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

^f UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^g HARVARD UNIVERSITY   (United States)

^h HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN PEROXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOXIA; ARTICLE; CARDIAC PROGENITOR CELL; CELL AGGREGATION; CELL CULTURE; CELL DEATH; CELL PROTECTION; CELL SURVIVAL; FEMALE; HEART INJURY; HEART MUSCLE CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; REOXYGENATION; STEM CELL; STEM CELL TRANSPLANTATION;

ADULT STEM CELLS; ANIMALS; CELL AGGREGATION; CELL CULTURE TECHNIQUES; CELL HYPOXIA; CELL SURVIVAL; FEMALE; HEART INJURIES; MALE; MICE; MYOCARDIUM; OXIDATIVE STRESS; SIDE-POPULATION CELLS;

MURINAE;

EID: 84870621671     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0050491     Document Type: Article

References (42)

1. Narula J, Haider N, Virmani R, DiSalvo TG, Kolodgie FD, et al. (1996) Apoptosis in myocytes in end-stage heart failure. N Engl J Med 335: 1182-1189.
2. Urbanek K, Torella D, Sheikh F, De Angelis A, Nurzynska D, et al. (2005) Myocardial regeneration by activation of multipotent cardiac stem cells in ischemic heart failure. Proc Natl Acad Sci U S A 102: 8692-8697.
3. Olivetti G, Abbi R, Quaini F, Kajstura J, Cheng W, et al. (1997) Apoptosis in the failing human heart. N Engl J Med 336: 1131-1141.
4. Ye Z, Zhou Y, Cai H, Tan W, (2011) Myocardial regeneration: Roles of stem cells and hydrogels. Adv Drug Deliv Rev 63: 688-697.
5. Ptaszek LM, Mansour M, Ruskin JN, Chien KR, (2012) Towards regenerative therapy for cardiac disease. Lancet 379: 933-942.
6. Bolli R, Chugh AR, D'Amario D, Loughran JH, Stoddard MF, et al. (2011) Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial. Lancet 378: 1847-1857.
7. Passier R, van Laake LW, Mummery CL, (2008) Stem-cell-based therapy and lessons from the heart. Nature 453: 322-329.
8. Bernstein HS, Srivastava D, (2012) Stem cell therapy for cardiac disease. Pediatr Res 71: 491-499.
9. Gnecchi M, Danieli P, Cervio E, (2012) Mesenchymal stem cell therapy for heart disease. Vascul Pharmacol 57: 48-55.
10. Makkar RR, Smith RR, Cheng K, Malliaras K, Thomson LE, et al. (2012) Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial. Lancet 379: 895-904.
11. Sanz-Ruiz R, Santos ME, Munoa MD, Martin IL, Parma R, et al. (2008) Adipose tissue-derived stem cells: the friendly side of a classic cardiovascular foe. J Cardiovasc Transl Res 1: 55-63.
12. Chiu RC, (2003) Bone-marrow stem cells as a source for cell therapy. Heart Fail Rev 8: 247-251.
13. Beltrami AP, Barlucchi L, Torella D, Baker M, Limana F, et al. (2003) Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 114: 763-776.
14. Haider H, Ashraf M, (2008) Strategies to promote donor cell survival: combining preconditioning approach with stem cell transplantation. J Mol Cell Cardiol 45: 554-566.
15. Wu KH, Mo XM, Han ZC, Zhou B, (2011) Stem cell engraftment and survival in the ischemic heart. Ann Thorac Surg 92: 1917-1925.
16. Birks EJ, Tansley PD, Hardy J, George RS, Bowles CT, et al. (2006) Left ventricular assist device and drug therapy for the reversal of heart failure. N Engl J Med 355: 1873-1884.
17. Zhang M, Methot D, Poppa V, Fujio Y, Walsh K, et al. (2001) Cardiomyocyte grafting for cardiac repair: graft cell death and anti-death strategies. J Mol Cell Cardiol 33: 907-921.
18. Penicka M, Widimsky P, Kobylka P, Kozak T, Lang O, (2005) Images in cardiovascular medicine. Early tissue distribution of bone marrow mononuclear cells after transcoronary transplantation in a patient with acute myocardial infarction. Circulation 112: e63-65.
19. Zhang H, Chen H, Wang W, Wei Y, Hu S, (2010) Cell survival and redistribution after transplantation into damaged myocardium. J Cell Mol Med 14: 1078-1082.
20. Tang YL, Tang Y, Zhang YC, Qian K, Shen L, et al. (2005) Improved graft mesenchymal stem cell survival in ischemic heart with a hypoxia-regulated heme oxygenase-1 vector. J Am Coll Cardiol 46: 1339-1350.
21. Lu G, Haider HK, Jiang S, Ashraf M, (2009) Sca-1+ stem cell survival and engraftment in the infarcted heart: dual role for preconditioning-induced connexin-43. Circulation 119: 2587-2596.
22. Bearzi C, Rota M, Hosoda T, Tillmanns J, Nascimbene A, et al. (2007) Human cardiac stem cells. Proc Natl Acad Sci U S A 104: 14068-14073.
23. Urbanek K, Cesselli D, Rota M, Nascimbene A, De Angelis A, et al. (2006) Stem cell niches in the adult mouse heart. Proc Natl Acad Sci U S A 103: 9226-9231.
24. Oyama T, Nagai T, Wada H, Naito AT, Matsuura K, et al. (2007) Cardiac side population cells have a potential to migrate and differentiate into cardiomyocytes in vitro and in vivo. J Cell Biol 176: 329-341.
25. Wang X, Hu Q, Nakamura Y, Lee J, Zhang G, et al. (2006) The role of the sca-1+/CD31- cardiac progenitor cell population in postinfarction left ventricular remodeling. Stem Cells 24: 1779-1788.
26. Akins RE, Boyce RA, Madonna ML, Schroedl NA, Gonda SR, et al. (1999) Cardiac organogenesis in vitro: reestablishment of three-dimensional tissue architecture by dissociated neonatal rat ventricular cells. Tissue Eng 5: 103-118.
27. Bartosh TJ, Wang Z, Rosales AA, Dimitrijevich SD, Roque RS, (2008) 3D-model of adult cardiac stem cells promotes cardiac differentiation and resistance to oxidative stress. J Cell Biochem 105: 612-623.
28. Pfister O, Mouquet F, Jain M, Summer R, Helmes M, et al. (2005) CD31- but Not CD31+ cardiac side population cells exhibit functional cardiomyogenic differentiation. Circ Res 97: 52-61.
29. Pfister O, Oikonomopoulos A, Sereti KI, Liao R, (2010) Isolation of resident cardiac progenitor cells by Hoechst 33342 staining. Methods Mol Biol 660: 53-63.
30. Swijnenburg RJ, Schrepfer S, Cao F, Pearl JI, Xie X, et al. (2008) In vivo imaging of embryonic stem cells reveals patterns of survival and immune rejection following transplantation. Stem Cells Dev 17: 1023-1029.
31. Pfister O, Oikonomopoulos A, Sereti KI, Sohn RL, Cullen D, et al. (2008) Role of the ATP-binding cassette transporter Abcg2 in the phenotype and function of cardiac side population cells. Circ Res 103: 825-835.
32. Oikonomopoulos A, Sereti KI, Conyers F, Bauer M, Liao A, et al. (2011) Wnt signaling exerts an antiproliferative effect on adult cardiac progenitor cells through IGFBP3. Circ Res 109: 1363-1374.
33. Kang L, Hancock MJ, Brigham MD, Khademhosseini A, (2010) Cell confinement in patterned nanoliter droplets in a microwell array by wiping. J Biomed Mater Res A 93: 547-557.
34. Jain M, DerSimonian H, Brenner DA, Ngoy S, Teller P, et al. (2001) Cell therapy attenuates deleterious ventricular remodeling and improves cardiac performance after myocardial infarction. Circulation 103: 1920-1927.
35. Bauwens CL, Peerani R, Niebruegge S, Woodhouse KA, Kumacheva E, et al. (2008) Control of human embryonic stem cell colony and aggregate size heterogeneity influences differentiation trajectories. Stem Cells 26: 2300-2310.
36. Chen CS, Pegan J, Luna J, Xia B, McCloskey K, et al. (2008) Shrinky-dink hanging drops: a simple way to form and culture embryoid bodies. J Vis Exp 13: 692.
37. Moeller HC, Mian MK, Shrivastava S, Chung BG, Khademhosseini A, (2008) A microwell array system for stem cell culture. Biomaterials 29: 752-763.
38. Kofidis T, de Bruin JL, Yamane T, Tanaka M, Lebl DR, et al. (2005) Stimulation of paracrine pathways with growth factors enhances embryonic stem cell engraftment and host-specific differentiation in the heart after ischemic myocardial injury. Circulation 111: 2486-2493.
39. Penn MS, Mangi AA, (2008) Genetic enhancement of stem cell engraftment, survival, and efficacy. Circ Res 102: 1471-1482.
40. Hu S, Huang M, Nguyen PK, Gong Y, Li Z, et al. (2011) Novel microRNA prosurvival cocktail for improving engraftment and function of cardiac progenitor cell transplantation. Circulation 124: S27-34.
41. Uggeri J, Gatti R, Belletti S, Scandroglio R, Corradini R, et al. (2004) Calcein-AM is a detector of intracellular oxidative activity. Histochem Cell Biol 122: 499-505.
42. Hwang YS, Chung BG, Ortmann D, Hattori N, Moeller HC, et al. (2009) Microwell-mediated control of embryoid body size regulates embryonic stem cell fate via differential expression of WNT5a and WNT11. Proc Natl Acad Sci U S A 106: 16978-16983.