Methylselenol Formed by Spontaneous Methylation of Selenide Is a Superior Selenium Substrate to the Thioredoxin and Glutaredoxin Systems

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Fernandes, Aristi P ^a   Wallenberg, Marita ^a   Gandin, Valentina ^b   Misra, Sougat ^a   Tisato, Francesco ^c   Marzano, Cristina ^b   Rigobello, Maria Pia ^b   Kumar, Sushil ^d   Björnstedt, Mikael ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF PADOVA   (Italy)

^c CNR   (Italy)

^d CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAREDOXIN; GLUTATHIONE; METHYLSELENOL; OXYGEN; S ADENOSYLMETHIONINE; SELENIDE; SELENITE; SELENIUM DERIVATIVE; SELENODIGLUTATHIONE; THIOL; THIOREDOXIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CELL TRANSPORT; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; IN VITRO STUDY; MASS SPECTROMETRY; METABOLITE; METHYLATION; MOLECULAR MECHANICS; OXIDATION REDUCTION REACTION; STOICHIOMETRY;

ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; CELL SURVIVAL; CYTOCHROMES C; DISULFIDES; GLUTAREDOXINS; GLUTATHIONE; HUMANS; INTRACELLULAR SPACE; METHANOL; METHYLATION; ORGANOSELENIUM COMPOUNDS; OXIDATION-REDUCTION; PROTEIN BINDING; S-ADENOSYLMETHIONINE; SELENIUM COMPOUNDS; SUPEROXIDES; THIOREDOXIN-DISULFIDE REDUCTASE; THIOREDOXINS;

ANIMALIA; MAMMALIA;

EID: 84870607151     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0050727     Document Type: Article

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