An insight into the protection of rat liver against ischemia/reperfusion injury by 2-selenium-bridged β-cyclodextrin

Hepatology Research

Volumn 39, Issue 11, 2009, Pages 1125-1136

  Lin, Ting ting ^a,b   Wang, Bing mei ^c   Li, Xin yang ^a   Pan, Yu ^a   Wang, Wei ^c   Mu, Ying ^a   Liu, Jun qiu ^b   Shen, Jia cong ^b   Luo, Gui min ^a  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b Jilin University   (China)

^c CHANGCHUN UNIVERSITY   (China)

Author keywords

2 selenium bridged cyclodextrin; Ebselen; Glutathione peroxidase; Ischemia reperfusion

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BETA CYCLODEXTRIN; CYTOCHROME C; EBSELEN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; MITOCHONDRIAL ENZYME; PROTEIN BAX; PROTEIN BCL 2; SELENIUM DERIVATIVE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME RELEASE; HISTOPATHOLOGY; LIVER CELL; LIVER INJURY; LIVER ISCHEMIA; LIVER PROTECTION; LOW DRUG DOSE; MALE; NONHUMAN; OPTIMAL DRUG DOSE; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; TISSUE STRUCTURE;

EID: 73649131270     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1872-034X.2009.00545.x     Document Type: Article

References (40)

1. Serracino-inglott F, Habib NA, Mathie R.T. Hepatic ischemia-reperfusion injury. Am J Surg 2001; 181: 160-6.
2. Carden DL, Granger D.N. Pathophysiology of ischaemiare perfusion injury. J Pathol 2000; 190: 255-66.
3. Kang K.J. Mechanism of hepatic ischemia/reperfusion injury and protection against reperfusion injury. Transplant Proc 2002; 34: 2659-61.
4. Zhang W, Wang M, Xie HY et al. Role of reactive oxygen species in mediating hepatic ischemia-reperfusion injury and its therapeutic applications in liver transplantation. Transplant Proc 2007; 39: 1332-7.
5. Mathews WR, Guido DM, Fisher MA, Jaeschke H. Lipid peroxidation as molecular mechanism of liver cell injury during reperfusion after ischemia. Free Radic Biol Med 1994; 16: 763-70.
6. Galaris D, Barbouti A, Korantzopoulos P. Oxidative stress in hepatic ischemia-reperfusion injury: the role of antioxidants and iron chelating compounds. Curr Pharm Des 2006; 12: 2875-90.
7. Ursini F, Maiorino M, Brigelius-Flohe R et al. Diversity of glutathione peroxidases. Methods Enzumol 1995; 252: 38-53.
8. Michiels C, Raes M, Toussaint O, Remade J. Importance of Se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress. Free Radic Biol Med 1994; 17: 235-48.
9. Sies H. Ebselen, a selenoorganic compound as glutathione peroxidase mimic. Free Radic Biol Med 1993; 14: 313-23.
10. Liu JQ, Gao SJ, Luo GM, Yan GL, Shen J.C. Artificial imitation of glutathione peroxidase with 6-selenium-bridged β-cyclodextrin. Biochem Biophys Res Commun 1998; 247: 397-400.
11. Mugesh G, du Mont W.W. Structure - activity correlation between natural glutathione peroxidase (GPx) and mimics: a biomimetic concept for the design and synthesis of more efficient GPx Mimics. Chemistry 2001; 7: 1365-70.
12. Chen J, Hong SS, An Y, Jiang GZ, Teng L.R. Preparation and kinetics of a novel glutathione peroxidase mimic - selenium-modified hyaluronic acid. Chem Res Chinese U 2007; 3: 325-8.
13. Wendel A, Fausel M, Safayhi H, Tiegs G, Otter R. A novel biologically active selenoorganic compound - I.I. Activity of PZ 51 in relation to glutathione peroxidase. Biochem Pharmacol 1984; 33: 3241-5.
14. Takasago T, Peters EE, Graham DI, Masayasu H, Macrae I.M. Neuroprotective efficacy of ebselen, an anti-oxidant with anti-inflammatory actions, in a rodent model of permanent middle cerebral artery occlusion. Br J Pharmacol 1997; 122: 1251-6.
15. Belvisi MG, Haddad EB, Battram C, Birrell M, Foster M, Webber S. Anti-inflammatory properties of ebselen in a model of sephadex-induced lung inflammation. Eur Respir J 2000; 15: 579-81.
16. Ozaki M, Nakamura M, Teraoka S, Ota K. Ebselen, a novel anti-oxidant compound, protects the rat liver from ischemia-reperfusion injury. Transpl Int 1997; 10: 96-102.
17. Imai H, Masayasu H, Dewar D et al. Ebselen protects both gray and white matter in a rodent model of focal cerebral ischemia. Stroke 2001; 32: 2149.
18. Yamagata K, Ichinose S, Miyashita A, Tagami M. Protective effects of ebselen, a seleno-organic antioxidant on neurodegeneration induced by hypoxia and reperfusion in stroke-prone spontaneously hypertensive rat. Neuroscience 2008; 153: 428-35.
19. Shida S, Kuzuya T, Nishida M et al. Ebselen protects against ischemia-reperfusion injury in a canine model of myocardial infarction. Am J Physiol Heart Circ Physiol 1994; 267: H2342-7.
20. Maulik N, Yoshida T. Oxidative stress developed during open heart surgery induces apoptosis: reduction of apoptotic cell death by ebselen, a glutathione peroxidase mimic. J Cardiovasc Pharmacol 2000; 36: 601-8.
21. Namura S, Nagata I, Takami S, Masayasu H, Kikuchi H. Ebselen reduces cytochrome c release from mitochondria and subsequent DNA fragmentation after transient focal cerebral ischemia in mice. Stroke 2001; 32: 1906-11.
22. Yamaguchi T. Phase III trial of Ebselen. The American Stroke Association 28th International Stroke Conference, Phoenix, Arizona, 2003. p. CTP20.
23. Liu JQ, Luo GM, Ren XJ, Mu Y. Bai Y, Shen J.C. A biscyclodextrin diselenide with glutathione peroxidase-like activity. BBA - Protein Struct M 2000; 1481: 222-8.
24. Mu Y, Lv SW, Ren XJ et al. UV-B induced keratinocyte apoptosis is blocked by 2-selenium-bridged β-cyclodextrin, a GPX mimic. J Photoch Photobio 2003; 69: 7-12.
25. Sun Y, Mu Y, Ma SM et al. The molecular mechanism of protecting cells against oxidative stress by 2-seleniumbridged b-cyclodextrin with glutathione peroxidase activity. BBA - Mol Cell Res 2005; 1743: 199-204.
26. Jia ZD, Lin F, Liu L, Mu Y, Yan GL, Luo G.M. Comparison between the effects of 2-Selenium Bridged β-Cyclodextrin and ebselen on treating SHRsp stroke. Chem Res Chinese U 2008; 24: 1-8.
27. Saravanan R, Prakasam A, Ramesh B, Pugalendi K.V. Influence of Piper betle on hepatic marker enzymes and tissue antioxidant status in ethanol-treated Wistar rats. J Med Food 2002; 5: 197-204.
28. Buege JA, Aust S.D. Microsomal lipid peroxidation. Methods Enzymol 1978; 52: 302-10.
29. Tietze F. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal Biochem 1969; 27: 502-22.
30. Krawisz JE, Sharon P, Stenson W.F. Quantitative assay of acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models. Gastroenterology 1984; 87: 1344-50.
31. Ozer J, Ratner M, Shaw M, Bailey W, Schomaker S. The current state of serum biomarker of hepatotoxicity. Toxicity 2008; 245: 194-205.
32. Simon HU, Hai-Yehia A, Levi-Schaffer F. Role of reactive oxygen species (ROS) in apoptosis induction. Apoptosis 2000; 5: 415-18.
33. Belcastro AN, Arthur GD, Albisser TA, Raj D.A. Heart, liver and skeletal muscle myeloperoxidase activity during exercise. J Appl Physiol 1996; 80: 1331-5.
34. Li P, Nijhawan D Budihardjo I et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997; 91: 479-89.
35. Liu X, Kim CN, Yang J, Jemmerson R, Wang X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 1996; 86: 147-57.
36. Zou H, Henzel WJ, Liu X, Lutschg A, Wang X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 1997; 90: 405-13.
37. Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, Nagata S. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 1998; 391: 43-50.
38. Hockenbery DM, Oltvai ZN, Yin XM, Milliman CL, Korsmeyer S.J. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 1993; 75: 241-51.
39. Scorrano L, Korsmeyer S.J. Mechanisms of cytochrome c release by proapoptotic BCL-2 family members. Biochem Biophys Res Commun 2003; 304: 437-44.
40. Breslow R. Studies in biomimetic chemistry Pure Appl Chem 1998; 70: 267-70.