Antibacterial and ulcer healing effects of organoselenium compounds in naproxen induced and Helicobacter pylori infected Wistar rat model

Journal of Trace Elements in Medicine and Biology

Volumn 24, Issue 4, 2010, Pages 263-270

  Santhosh Kumar, B ^a   Tiwari, Santosh K ^b   Saikant, R ^b   Manoj, G ^b   Kunwar, Amit ^c   Sivaram, G ^b   Abid, Zakia ^a   Ahmad, Adeel ^d   Priyadarsini, K Indira ^c   Khan, Aleem A ^b  

^a DECCAN COLLEGE OF MEDICAL SCIENCES   (India)

^b DECCAN COLLEGE OF MEDICAL SCIENCES   (India)

^c BHABHA ATOMIC RESEARCH CENTRE   (India)

^d OSMANIA UNIVERSITY   (India)

Author keywords

Anti inflammation; Antibacterial activity; Antiulcer activity; Ebselen; Helicobacter pylori; Immunomodulation; Selenocystine

Indexed keywords

CYCLOOXYGENASE 2; EBSELEN; GLUTATHIONE; IMMUNOGLOBULIN G; INTERLEUKIN 10; INTERLEUKIN 6; MANGANESE SUPEROXIDE DISMUTASE; NAPROXEN; ORGANOSELENIUM DERIVATIVE; PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE; REACTIVE OXYGEN METABOLITE; SELENOCYSTINE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CD4 LYMPHOCYTE COUNT; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; GENE EXPRESSION REGULATION; HELICOBACTER INFECTION; HELICOBACTER PYLORI; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; LIPID PEROXIDATION; NONHUMAN; PRIORITY JOURNAL; RAT; SPLEEN LYMPHOCYTE; STOMACH PROTECTION; TOXICITY TESTING; ULCER HEALING; WISTAR RAT;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-ULCER AGENTS; ANTIOXIDANTS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; IMMUNOGLOBULIN G; INTERLEUKIN-10; INTERLEUKIN-6; NAPROXEN; ORGANOSELENIUM COMPOUNDS; OXIDATIVE STRESS; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STOMACH ULCER; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

HELICOBACTER PYLORI; RATTUS NORVEGICUS; RODENTIA;

EID: 78549249149     PISSN: 0946672X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jtemb.2010.04.003     Document Type: Article

References (42)

1. Forman D., Newell D.G., Fullerton F., Yarnell J.W., Stacey A.R., Wald N., et al. Association between infection with Helicobacter pylori and risk of gastric cancer: evidence from a prospective investigation. Br Med J 1991, 302:1302-1305.
2. Parsonnet J., Hansen S., Rodriguez L., Gelb A.B., Warnke R.A., Jellum E., et al. Helicobacter pylori infection and gastric lymphoma. N Engl J Med 1994, 330:1267-1271.
3. Asaka M., Takeda T., Sugiyama, Kato M. What role does Helicobacter pylori play in gastric cancer. Gastroenterology 1997, 113:56-60.
4. Manoj G., Tiwari S.K., Sharma V., Habeeb M.A., Khan A.A., Habibullah C.M. Association of Helicobacter pylori restriction endonuclease-replacing gene, hrgA with overt gastrointestinal diseases. Arq Gastroentrol 2008, 43:225-229.
5. Winfried B., Barbara O., Karl-Friedrich S., Siegfried W. Helicobacter pylori reduces intracellular glutathione in gastric epithelial cells. Dig Dis Sci 2000, 45(9):1769-1773.
6. De Boer W.A., Tytgat G.N. Treatment of Helicobacter pylori infection. Br Med J 2000, 320:31-34.
7. Kupcinskas L., Lafolie P., Lignell A., Kiudelis G., Jonaitis L., Adamonis K., et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: a prospective, randomized, double-blind and placebo-controlled study. Phytomedicine 2008, 15(6-7):391-399.
8. Comasseto J.V., Lo W.L., Petragnani N. Carbonyl transposition on organoselenium compounds. Tetrahedron 1997, 7445-7460.
9. Ayyanar M., Ignacimuthu S. Pharmacological actions of Cassia auriculata L and Cissus quadrangularis wall. J Pharmacol Toxicol 2008, 3(3):213-221.
10. Santhosh Kumar B., Amit Kunwar, Ahmad A., Kumbhare L.B., Jain V.K., Priyadarsini K.I. Radioprotection of biomolecules by organoselenium compounds-differences between mono and diselenides. Rad Environ Biophys 2009, 48(4):379-384.
11. Ocakci A., Coskun O., Tumkaya L., Kanter M., Gurel A., Hosnuter M., et al. Beneficial effects of Ebselen on corrosive esophageal burns of rats. Int J Pediat Otorhinolaryngol 2006, 70(1):45-52.
12. Ali S.M., Khan A.A., Ahmed I., Musaddiq M., Ahmed K.S., Polasa H., et al. Antimicrobial activities of Eugenol and Cinnamaldehyde against the human gastric pathogen Helicobacter pylori. Ann Clin Microbiol Antimicrob 2005, 4:20.
13. Ibrahim M., Khan A.A., Tiwari S.K., Habeeb M.A., Khaja M.N., Habibullah C.M. Antimicrobial activity of Sapindus mukorossi and Rheum emodi extracts against H. pylori: in vitro and in vivo studies. World J Gastroenterol 2005, 12:7136-7142.
14. Santhosh K.B., Tiwari S.K., Manoj G., Kunwar A., Amrita N., Sivaram G., et al. Antimicrobial and anti-ulcer activities of sodium selenite against Helicobacter pylori: in vitro and in vivo evaluation. Scand J Infect Dis 2009, (Available online).
15. Tiwari S.K., Manoj G., Kumar G.V., Sivaram G., Hassan S.I., Prabhakar B., et al. Prognostic significance of genotyping Helicobacter pylori infection in patients in younger age groups with gastric cancer. Postgrad Med J 2008, 84:193-197.
16. Kunwar A., Mishra B., Barik A., Kumbhare L.B., Pandey R., Jain V.K., et al. 3,3′-Diselenodipropionic acid, an efficient peroxyl radical scavenger and a GPx mimic, protects erythrocytes (RBCs) from AAPH-induced hemolysis. Chem Res Toxicol 2007, 20(10):1482-1487.
17. Elliott S.N., Buret A., McKnight W., Miller M.J., Wallace J.L. Bacteria rapidly colonize and modulate healing of gastric ulcers in rats. Am J Physiol Gastrointest Liver Physiol 1998, 275:425-432.
18. Watanabe T., Tada M., Nagai H., Sasaki S., Nakao M. Helicobacter pylori infection induces gastric cancer in Mongolian gerbils. Gastroenterology 1998, 115:642-648.
19. Urbanits S.B., Griesmacherb A., Hopfingerc G., Stockhammerd G., Karimib A., Müllerb M.M., et al. FACS analysis-a new and accurate tool in the diagnosis of lymphoma in the cerebrospinal fluid. Clin Chim Acta 2002, 317:101-107.
20. Kawakami M., Kaneko N., Anada H., Terai C., Okada Y. Measurement of interleukin-6, interleukin-10, and tumor necrosis factor-alpha levels in tissues and plasma after thermal injury in mice. Surgery 1997, 121(4):440-448.
21. Lawler J.M., Kwak H.B., Kim J.H., Suk M.H. Exercise training inducibility of MnSOD protein expression and activity is retained while reducing prooxidant signaling in the heart of senescent rats. Am J Physiol Regul Integr Comp Physiol 2009, 296:1496-1502.
22. Kobayashi D., Kondo K., Uehara N., Otokozawa S., Tsuji N., Yagihashi A., et al. Endogenous reactive oxygen species is an important endogenous reactive oxygen species is an important mediator of miconazole antifungal effect. Phytomedicine 2008, 15(6-7):391-399.
23. Suzuki H., Mori M., Seto K., Kai A., Kawaguchi C., Suzuki M., et al. Helicobacter pylori-associated gastric pro- and antioxidant formation in Mongolian gerbils. Free Radic Biol Med 1999, 26:679-684.
24. Okiyama W., Tanaka N., Nakajima T., Tanaka E., Kiyosawa K., Gonzalez F., et al. Polyenephosphatidyl choline prevents alcoholic liver disease in PPARα-null mice through attenuation of increases in oxidative stress. J Hepatol 2004, 50(6):1236-1246.
25. Dixon M.F., Genta R.M., Yardley J.H., Correa P. Classification and grading of gastritis: the updated Sydney system. Am J Surg Pathol 1996, 20:1161-1181.
26. Hull M., Thomson, Hawkey C. Expression of cyclooxygenase 1 and 2 by human gastric endothelial cells. Gut 1999, 45(4):529-536.
27. Holecek V., Rokyta R., Vlasak R. Antioxidants and their gastrointestinal absorption and interferences of their effects. Cesk Fysiol 2008, 57:24-32.
28. Garcia S.M. Organoselenium compounds as potential therapeutic and chemopreventive agents: a review. Curr Med Chem 2004, 11:1657-1669.
29. Zhong W., Oberley T.D. Redox-mediated effects of selenium on apoptosis and cell cycle in the LNCaP human prostate cancer cell line. Cancer Res 2001, 61:7071-7078.
30. Drake I.M., Davies M.J., Mapstone N.P., Dixon M.F., Schorah C.J., White K.L., et al. Ascorbic acid may protect against human gastric cancer by scavenging mucosal oxygen radicals. Carcinogenesis 1996, 17:559-562.
31. Naito Y., Yoshikawa T. Molecular and cellular mechanisms involved in Helicobacter pylori induced inflammation and oxidative stress. Free Radic Biol Med 2002, 33(3):323-336.
32. Shirin H., Pinto J.T., Liu L.U. Helicobacter pylori decreases gastric mucosal glutathione. Cancer Lett 2001, 64:127-133.
33. Zhao C., Wang X., Friis-Hansen L., Waldum H.L., Halgunset J., Wadström T., et al. Chronic Helicobacter pylori infection results in gastric hypoacidity and hypergastrinemia in wild-type mice but vagally induced hypersecretion in gastrin-deficient mice. Regul Peptides 2003, 115(3):161-170.
34. Gan K.H., Geus W.P., Heijerman H.G.M., Bakker W., Lamers C.B.H.W. Effect of omeprazole on intraduodenal and intragastric pH in healthy volunteers. Gastroenterology 1995, 108(4):98.
35. Holck S., Nørgaard A., Bennedsen M., Permin H., Norn S., Andersen L.P. Gastric mucosal cytokine response in Helicobacter pylori-infected patients with gastritis and peptic ulcer. FEMS Immunol Med Microbiol 2003, 36(3):175-180.
36. Xu C.L., Wang Y.Z., Jin M.L., Yang X.Q. Preparation, characterization and immunomodulatory activity of selenium enriched exopolysaccharide produced by bacterium Enterobacter cloacae Z0206. Bioresour Technol 2009, 100(6):2095-2097.
37. Pisit T., Duangporn T., Apiradee T., Orrawadee H., Pinit K., Yong P. Diagnostic role of serum interleukin-6 and CA 19-9 in patients with cholangiocarcinoma. Hepatogastroenterology 2004, 51(55):15-19.
38. Jozsef K., Dillner J. Immunity to oncogenic human papilloma viruses. Adv Cancer Res 2001, 82:205-238.
39. Lim H., Song H., Paria B.C., Reese J., Das S.K., Dey S.K. Molecules in blastocyst implantation: uterine and embryonic perspectives. Vit Horm 2002, 64:43-76.
40. Gotz J.M., Thio J.L., Verspaget H.W., Offerhaus G.J., BiemondI, Lamers C.B., et al. Treatment of Helicobacter pylori infection favourably affects gastric mucosal superoxide dismutases. Gut 1997, 40:591-596.
41. Gambero A., Becker T.L., Gurgueira S.A., Benvengo H.B., Ribeiro M.L., de Mendonça S., et al. Acute inflammatory response induced by Helicobacter pylori in the rat air pouch. FEMS Immunol Med Microbiol 2003, 38(3):193-198.
42. Ineu R.P., Pereira M.E., Aschner M., Nogueira C.W., Zeni G., Rocha J.B.T. Diphenyl diselenide reverses gastric lesions in rats: involvement of oxidative stress. Food Chem Toxicol 2008, 46:3023-3029.