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Volumn 32, Issue 12, 2012, Pages 2153-2160

Anomalous diffusion of brain metabolites evidenced by diffusion-weighted magnetic resonance spectroscopy in vivo

Author keywords

anomalous diffusion; brain metabolite; diffusion; intracellular transport; magnetic resonance

Indexed keywords

CHOLINE; CREATINE; GLYCEROPHOSPHORYLCHOLINE; N ACETYLASPARTIC ACID; PHOSPHORYLCHOLINE;

EID: 84870592480     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2012.119     Document Type: Article
Times cited : (48)

References (40)
  • 2
    • 0036164351 scopus 로고    scopus 로고
    • Solute and macromolecule diffusion in cellular aqueous compartments
    • Verkman AS. Solute and macromolecule diffusion in cellular aqueous compartments. Trends Biochem Sci 2002; 27: 27-33.
    • (2002) Trends Biochem Sci , vol.27 , pp. 27-33
    • Verkman, A.S.1
  • 3
    • 77952294035 scopus 로고    scopus 로고
    • Elucidating anomalous protein diffusion in living cells with fluorescence correlation spectroscopy-facts and pitfalls
    • Malchus N, Weiss M. Elucidating anomalous protein diffusion in living cells with fluorescence correlation spectroscopy-facts and pitfalls. J Fluoresc 2010; 20: 19-26.
    • (2010) J Fluoresc , vol.20 , pp. 19-26
    • Malchus, N.1    Weiss, M.2
  • 4
    • 0034499331 scopus 로고    scopus 로고
    • Enhanced diffusion in active intracellular transport
    • Caspi A, Granek R, Elbaum M. Enhanced diffusion in active intracellular transport. Phys Rev Lett 2000; 85: 5655-5658.
    • (2000) Phys Rev Lett , vol.85 , pp. 5655-5658
    • Caspi, A.1    Granek, R.2    Elbaum, M.3
  • 5
    • 33751019968 scopus 로고    scopus 로고
    • Anomalous diffusion in Purkinje cell dendrites caused by spines
    • Santamaria F, Wils S, De Schutter E, Augustine GJ. Anomalous diffusion in Purkinje cell dendrites caused by spines. Neuron 2006; 52: 635-648.
    • (2006) Neuron , vol.52 , pp. 635-648
    • Santamaria, F.1    Wils, S.2    De Schutter, E.3    Augustine, G.J.4
  • 6
    • 12244265509 scopus 로고    scopus 로고
    • Oscillating gradient measurements of water diffusion in normal and globally ischemic rat brain
    • Does MD, Parsons EC, Gore JC. Oscillating gradient measurements of water diffusion in normal and globally ischemic rat brain. Magn Reson Med 2003; 49: 206-215.
    • (2003) Magn Reson Med , vol.49 , pp. 206-215
    • Does, M.D.1    Parsons, E.C.2    Gore, J.C.3
  • 7
    • 0033622118 scopus 로고    scopus 로고
    • Vivo (31)P-NMR diffusion spectroscopy of ATP and phosphocreatine in rat skeletal muscle
    • de Graaf RA, van Kranenburg A, Nicolay K. In vivo (31)P-NMR diffusion spectroscopy of ATP and phosphocreatine in rat skeletal muscle. Biophys J 2000; 78: 1657-1664.
    • (2000) Biophys J , vol.78 , pp. 1657-1664
    • De Graaf, R.A.1    Van Kranenburg, A.2    Nicolay, K.3
  • 8
    • 12244271627 scopus 로고
    • Frequency-domain analysis of spin motion using modulated-gradient NMR
    • Callaghan PT, Stepisnik J. Frequency-domain analysis of spin motion using modulated-gradient NMR. J Magn Reson Ser A 1995; 117: 118-122.
    • (1995) J Magn Reson ser A , vol.117 , pp. 118-122
    • Callaghan, P.T.1    Stepisnik, J.2
  • 9
    • 0035576417 scopus 로고    scopus 로고
    • Diffusion and flow in a porous structure by the gradient spin echo spectral analysis
    • Stepisnik J, Mohoric A, Duh A. Diffusion and flow in a porous structure by the gradient spin echo spectral analysis. Physica B 2001; 307: 158-168.
    • (2001) Physica B , vol.307 , pp. 158-168
    • Stepisnik, J.1    Mohoric, A.2    Duh, A.3
  • 10
    • 0035742326 scopus 로고    scopus 로고
    • The return of the frequency sweep: Designing adiabatic pulses for contemporary NMR
    • Garwood M, DelaBarre L. The return of the frequency sweep: designing adiabatic pulses for contemporary NMR. J Magn Reson 2001; 153: 155-177.
    • (2001) J Magn Reson , vol.153 , pp. 155-177
    • Garwood, M.1    Delabarre, L.2
  • 11
    • 0027375098 scopus 로고
    • Estimation of metabolite concentrations from localized in vivo proton NMR spectra
    • Provencher SW. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn Reson Med 1993; 30: 672-679.
    • (1993) Magn Reson Med , vol.30 , pp. 672-679
    • Provencher, S.W.1
  • 12
    • 0027590414 scopus 로고
    • Time-dependent self-diffusion by NMR spin-echo
    • Stepisnik J. Time-dependent self-diffusion by NMR spin-echo. Physica B 1993; 183: 343-350.
    • (1993) Physica B , vol.183 , pp. 343-350
    • Stepisnik, J.1
  • 13
    • 0345253859 scopus 로고    scopus 로고
    • Validity limits of Gaussian approximation in cumulant expansion for diffusion attenuation of spin echo
    • Stepisnik J. Validity limits of Gaussian approximation in cumulant expansion for diffusion attenuation of spin echo. Physica B 1999; 270: 110-117.
    • (1999) Physica B , vol.270 , pp. 110-117
    • Stepisnik, J.1
  • 14
    • 0014047008 scopus 로고
    • The occurrence of a cyclosis-like phenomenon in human lung cancer cells in vitro
    • Sherwin RP, Richters A, Richters V. The occurrence of a cyclosis-like phenomenon in human lung cancer cells in vitro. Cancer Res 1967; 27: 152-158.
    • (1967) Cancer Res , vol.27 , pp. 152-158
    • Sherwin, R.P.1    Richters, A.2    Richters, V.3
  • 15
    • 80053488949 scopus 로고    scopus 로고
    • Dynamic maintenance of asymmetric meiotic spindle position through Arp2/3-complex-driven cytoplasmic streaming in mouse oocytes
    • Yi K, Unruh JR, Deng M, Slaughter BD, Rubinstein B, Li R. Dynamic maintenance of asymmetric meiotic spindle position through Arp2/3-complex-driven cytoplasmic streaming in mouse oocytes. Nat Cell Biol 2011; 13: 1252-1258.
    • (2011) Nat Cell Biol , vol.13 , pp. 1252-1258
    • Yi, K.1    Unruh, J.R.2    Deng, M.3    Slaughter, B.D.4    Rubinstein, B.5    Li, R.6
  • 16
    • 0028863259 scopus 로고
    • Intracellular transport mechanisms: A critique of diffusion theory
    • Agutter PS, Malone PC, Wheatley DN. Intracellular transport mechanisms: a critique of diffusion theory. J Theor Biol 1995; 176: 261-272.
    • (1995) J Theor Biol , vol.176 , pp. 261-272
    • Agutter, P.S.1    Malone, P.C.2    Wheatley, D.N.3
  • 18
    • 0033013978 scopus 로고    scopus 로고
    • On the vital role of fluid movement in organisms and cells: A brief historical account from Harvey to Coulson, extending the hypothesis of circulation
    • Wheatley DN. On the vital role of fluid movement in organisms and cells: a brief historical account from Harvey to Coulson, extending the hypothesis of circulation. Med Hypotheses 1999; 52: 275-284.
    • (1999) Med Hypotheses , vol.52 , pp. 275-284
    • Wheatley, D.N.1
  • 19
    • 77958522195 scopus 로고    scopus 로고
    • The use of MR-detectable reporter molecules and ions to evaluate diffusion in normal and ischemic brain
    • Ackerman JJ, Neil JJ. The use of MR-detectable reporter molecules and ions to evaluate diffusion in normal and ischemic brain. NMR Biomed 2010; 23: 725-733.
    • (2010) NMR Biomed , vol.23 , pp. 725-733
    • Ackerman, J.J.1    Neil, J.J.2
  • 20
    • 0033389207 scopus 로고    scopus 로고
    • Changes in the diffusion of water and intracellular metabolites after excitotoxic injury and global ischemia in neonatal rat brain
    • Dijkhuizen RM, de Graaf RA, Tulleken KA, Nicolay K. Changes in the diffusion of water and intracellular metabolites after excitotoxic injury and global ischemia in neonatal rat brain. J Cereb Blood Flow Metab 1999; 19: 341-349.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 341-349
    • Dijkhuizen, R.M.1    De Graaf, R.A.2    Tulleken, K.A.3    Nicolay, K.4
  • 21
    • 0035108836 scopus 로고    scopus 로고
    • Changes in apparent diffusion coefficients of metabolites in rat brain after middle cerebral artery occlusion measured by proton magnetic resonance spectroscopy
    • Dreher W, Busch E, Leibfritz D. Changes in apparent diffusion coefficients of metabolites in rat brain after middle cerebral artery occlusion measured by proton magnetic resonance spectroscopy. Magn Reson Med 2001; 45: 383-389.
    • (2001) Magn Reson Med , vol.45 , pp. 383-389
    • Dreher, W.1    Busch, E.2    Leibfritz, D.3
  • 22
    • 0036183312 scopus 로고    scopus 로고
    • Diffusion-weighted in vivo localized proton MR spectroscopy of human cerebral ischemia and tumor
    • Harada M, Uno M, Hong F, Hisaoka S, Nishitani H, Matsuda T. Diffusion-weighted in vivo localized proton MR spectroscopy of human cerebral ischemia and tumor. NMR Biomed 2002; 15: 69-74.
    • (2002) NMR Biomed , vol.15 , pp. 69-74
    • Harada, M.1    Uno, M.2    Hong, F.3    Hisaoka, S.4    Nishitani, H.5    Matsuda, T.6
  • 23
    • 0029913999 scopus 로고    scopus 로고
    • Diffusion of metabolites in normal and ischemic rat brain measured by localized 1H MRS
    • van der Toorn A, Dijkhuizen RM, Tulleken CA, Nicolay K. Diffusion of metabolites in normal and ischemic rat brain measured by localized 1H MRS. Magn Reson Med 1996; 36: 914-922.
    • (1996) Magn Reson Med , vol.36 , pp. 914-922
    • Van Der Toorn, A.1    Dijkhuizen, R.M.2    Tulleken, C.A.3    Nicolay, K.4
  • 24
    • 0028140412 scopus 로고
    • Anomalous diffusion due to obstacles: A Monte Carlo study
    • Saxton MJ. Anomalous diffusion due to obstacles: a Monte Carlo study. Biophys J 1994; 66: 394-401.
    • (1994) Biophys J , vol.66 , pp. 394-401
    • Saxton, M.J.1
  • 25
    • 0027265566 scopus 로고
    • Human brain: Proton diffusion MR spectroscopy
    • Posse S, Cuenod CA, Le Bihan D. Human brain: proton diffusion MR spectroscopy. Radiology 1993; 188: 719-725.
    • (1993) Radiology , vol.188 , pp. 719-725
    • Posse, S.1    Cuenod, C.A.2    Le Bihan, D.3
  • 26
    • 0027412386 scopus 로고
    • Molecular selfdiffusion of intracellular metabolites in rat brain in vivo investigated by localized proton NMR diffusion spectroscopy
    • Merboldt KD, Horstermann D, Hanicke W, Bruhn H, Frahm J. Molecular selfdiffusion of intracellular metabolites in rat brain in vivo investigated by localized proton NMR diffusion spectroscopy. Magn Reson Med 1993; 29: 125-129.
    • (1993) Magn Reson Med , vol.29 , pp. 125-129
    • Merboldt, K.D.1    Horstermann, D.2    Hanicke, W.3    Bruhn, H.4    Frahm, J.5
  • 27
    • 0029090537 scopus 로고
    • Alteration of intracellular metabolite diffusion in rat brain in vivo during ischemia and reperfusion
    • discussion 1934
    • Wick M, Nagatomo Y, Prielmeier F, Frahm J. Alteration of intracellular metabolite diffusion in rat brain in vivo during ischemia and reperfusion. Stroke 1995; 26: 1930-1933; discussion 1934.
    • (1995) Stroke , vol.26 , pp. 1930-1933
    • Wick, M.1    Nagatomo, Y.2    Prielmeier, F.3    Frahm, J.4
  • 28
    • 0035035793 scopus 로고    scopus 로고
    • Single-shot diffusion trace (1)H NMR spectroscopy
    • de Graaf RA, Braun KP, Nicolay K. Single-shot diffusion trace (1)H NMR spectroscopy. Magn Reson Med 2001; 45: 741-748.
    • (2001) Magn Reson Med , vol.45 , pp. 741-748
    • De Graaf, R.A.1    Braun, K.P.2    Nicolay, K.3
  • 29
    • 17544368789 scopus 로고    scopus 로고
    • Temporal changes of the apparent diffusion coefficients of water and metabolites in rats with hemispheric infarction: Experimental study of transhemispheric diaschisis in the contralateral hemisphere at 7 tesla
    • Abe O, Okubo T, Hayashi N, Saito N, Iriguchi N, Shirouzu I et al. Temporal changes of the apparent diffusion coefficients of water and metabolites in rats with hemispheric infarction: experimental study of transhemispheric diaschisis in the contralateral hemisphere at 7 tesla. J Cereb Blood Flow Metab 2000; 20: 726-735.
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 726-735
    • Abe, O.1    Okubo, T.2    Hayashi, N.3    Saito, N.4    Iriguchi, N.5    Shirouzu, I.6
  • 30
    • 79952679420 scopus 로고    scopus 로고
    • Considerations for measuring the fractional anisotropy of metabolites with diffusion tensor spectroscopy
    • Ellegood J, Hanstock CC, Beaulieu C. Considerations for measuring the fractional anisotropy of metabolites with diffusion tensor spectroscopy. NMR Biomed 2011; 24: 270-280.
    • (2011) NMR Biomed , vol.24 , pp. 270-280
    • Ellegood, J.1    Hanstock, C.C.2    Beaulieu, C.3
  • 31
    • 0032148386 scopus 로고    scopus 로고
    • Quantitative 1H nuclear magnetic resonance diffusion spectroscopy of BT4C rat glioma during thymidine kinase-mediated gene therapy in vivo: Identification of apoptotic response
    • Hakumaki JM, Poptani H, Puumalainen AM, Loimas S, Paljarvi LA, Yla-Herttuala S et al. Quantitative 1H nuclear magnetic resonance diffusion spectroscopy of BT4C rat glioma during thymidine kinase-mediated gene therapy in vivo: identification of apoptotic response. Cancer Res 1998; 58: 3791-3799.
    • (1998) Cancer Res , vol.58 , pp. 3791-3799
    • Hakumaki, J.M.1    Poptani, H.2    Puumalainen, A.M.3    Loimas, S.4    Paljarvi, L.A.5    Yla-Herttuala, S.6
  • 32
    • 18244367681 scopus 로고    scopus 로고
    • Trace apparent diffusion coefficients of metabolites in human brain using diffusion weighted magnetic resonance spectroscopy
    • Ellegood J, Hanstock CC, Beaulieu C. Trace apparent diffusion coefficients of metabolites in human brain using diffusion weighted magnetic resonance spectroscopy. Magn Reson Med 2005; 53: 1025-1032.
    • (2005) Magn Reson Med , vol.53 , pp. 1025-1032
    • Ellegood, J.1    Hanstock, C.C.2    Beaulieu, C.3
  • 33
    • 29544433365 scopus 로고    scopus 로고
    • Optimized diffusion-weighted spectroscopy for measuring brain glutamate apparent diffusion coefficient on a whole-body MR system
    • Valette J, Guillermier M, Besret L, Boumezbeur F, Hantraye P, Lebon V. Optimized diffusion-weighted spectroscopy for measuring brain glutamate apparent diffusion coefficient on a whole-body MR system. NMR Biomed 2005; 18: 527-533.
    • (2005) NMR Biomed , vol.18 , pp. 527-533
    • Valette, J.1    Guillermier, M.2    Besret, L.3    Boumezbeur, F.4    Hantraye, P.5    Lebon, V.6
  • 34
    • 33847214861 scopus 로고    scopus 로고
    • Isoflurane strongly affects the diffusion of intracellular metabolites, as shown by 1H nuclear magnetic resonance spectroscopy of the monkey brain
    • Valette J, Guillermier M, Besret L, Hantraye P, Bloch G, Lebon V. Isoflurane strongly affects the diffusion of intracellular metabolites, as shown by 1H nuclear magnetic resonance spectroscopy of the monkey brain. J Cereb Blood Flow Metab 2007; 27: 588-596.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 588-596
    • Valette, J.1    Guillermier, M.2    Besret, L.3    Hantraye, P.4    Bloch, G.5    Lebon, V.6
  • 35
    • 0034048817 scopus 로고    scopus 로고
    • Extracellular-intracellular distribution of glucose and lactate in the rat brain assessed noninvasively by diffusion-weighted 1H nuclear magnetic resonance spectroscopy in vivo
    • Pfeuffer J, Tkac I, Gruetter R. Extracellular-intracellular distribution of glucose and lactate in the rat brain assessed noninvasively by diffusion-weighted 1H nuclear magnetic resonance spectroscopy in vivo. J Cereb Blood Flow Metab 2000; 20: 736-746.
    • (2000) J Cereb Blood Flow Metab , vol.20 , pp. 736-746
    • Pfeuffer, J.1    Tkac, I.2    Gruetter, R.3
  • 36
  • 37
    • 7544232782 scopus 로고    scopus 로고
    • On the nature of the NAA diffusion attenuated MR signal in the central nervous system
    • Kroenke CD, Ackerman JJ, Yablonskiy DA. On the nature of the NAA diffusion attenuated MR signal in the central nervous system. Magn Reson Med 2004; 52: 1052-1059.
    • (2004) Magn Reson Med , vol.52 , pp. 1052-1059
    • Kroenke, C.D.1    Ackerman, J.J.2    Yablonskiy, D.A.3
  • 38
    • 35948982240 scopus 로고    scopus 로고
    • Diffusion properties of NAA in human corpus callosum as studied with diffusion tensor spectroscopy
    • Upadhyay J, Hallock K, Erb K, Kim DS, Ronen I. Diffusion properties of NAA in human corpus callosum as studied with diffusion tensor spectroscopy. Magn Reson Med 2007; 58: 1045-1053.
    • (2007) Magn Reson Med , vol.58 , pp. 1045-1053
    • Upadhyay, J.1    Hallock, K.2    Erb, K.3    Kim, D.S.4    Ronen, I.5
  • 39
    • 33845996200 scopus 로고    scopus 로고
    • RT, Hanstock CC, Beaulieu C. Anisotropic diffusion of metabolites in peripheral nerve using diffusion weighted magnetic resonance spectroscopy at ultra-high field
    • McKay
    • Ellegood J, McKay RT, Hanstock CC, Beaulieu C. Anisotropic diffusion of metabolites in peripheral nerve using diffusion weighted magnetic resonance spectroscopy at ultra-high field. J Magn Reson 2007; 184: 20-28.
    • (2007) J Magn Reson , vol.184 , pp. 20-28
    • Ellegood, J.1
  • 40
    • 78650251838 scopus 로고    scopus 로고
    • Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration
    • Hoover BR, Reed MN, Su J, Penrod RD, Kotilinek LA, Grant MK et al. Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration. Neuron 2010; 68: 1067-1081.
    • (2010) Neuron , vol.68 , pp. 1067-1081
    • Hoover, B.R.1    Reed, M.N.2    Su, J.3    Penrod, R.D.4    Kotilinek, L.A.5    Grant, M.K.6


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