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Volumn 5, Issue 6, 2012, Pages 498-501

The podocyte cytoskeleton in health and in disease

Author keywords

actin; cytoskeleton; podocyte; proteinuria

Indexed keywords

ALPHA ACTININ 4; CALCINEURIN; CALCIUM SENSING RECEPTOR; CYCLOSPORIN; DEXAMETHASONE; DOXORUBICIN; GLITAZONE DERIVATIVE; MUTANT PROTEIN; PROTEIN CDC42; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SYNAPTOPODIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84870560266     PISSN: 20488505     EISSN: 20488513     Source Type: Journal    
DOI: 10.1093/ckj/sfs153     Document Type: Review
Times cited : (16)

References (27)
  • 1
    • 77953291706 scopus 로고    scopus 로고
    • Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: A collaborative meta-analysis
    • Chronic Kidney Disease Prognosis Consortium
    • Chronic Kidney Disease Prognosis Consortium. Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis. Lancet 2010; 375: 2073-2081
    • (2010) Lancet , vol.375 , pp. 2073-2081
  • 2
    • 84866658486 scopus 로고    scopus 로고
    • Biomarkers of diabetic nephropathy, the present and the future
    • Jim B, Santos J, Spath F et al. Biomarkers of diabetic nephropathy, the present and the future. Curr Diabetes Rev 2012; 8: 317-328
    • (2012) Curr Diabetes Rev , vol.8 , pp. 317-328
    • Jim, B.1    Santos, J.2    Spath, F.3
  • 3
    • 84859652025 scopus 로고    scopus 로고
    • Pathobiology of focal segmental glomerulosclerosis: New developments
    • D'Agati VD. Pathobiology of focal segmental glomerulosclerosis: new developments. Curr Opin Nephrol Hypertens 2012; 21: 243-250
    • (2012) Curr Opin Nephrol Hypertens , vol.21 , pp. 243-250
    • D'Agati, V.D.1
  • 4
    • 84455208254 scopus 로고    scopus 로고
    • The podocyte as a target for therapies-new and old
    • Mathieson PW. The podocyte as a target for therapies-new and old. Nat Rev Nephrol 2011; 8: 52-56
    • (2011) Nat Rev Nephrol , vol.8 , pp. 52-56
    • Mathieson, P.W.1
  • 5
    • 77955012444 scopus 로고    scopus 로고
    • Hereditary nephrotic syndrome: A systematic approach for genetic testing and a review of associated podocyte gene mutations
    • Benoit G, Machuca E, Antignac C. Hereditary nephrotic syndrome: a systematic approach for genetic testing and a review of associated podocyte gene mutations. Pediatr Nephrol 2010; 25: 1621-1632
    • (2010) Pediatr Nephrol , vol.25 , pp. 1621-1632
    • Benoit, G.1    MacHuca, E.2    Antignac, C.3
  • 7
    • 0036893492 scopus 로고    scopus 로고
    • Inherited podocytopathies: FSGS and nephrotic syndrome from a genetic viewpoint
    • DOI 10.1097/01.ASN.0000039569.34360.5E
    • Pollak MR. Inherited podocytopathies: FSGS and nephrotic syndrome from a genetic viewpoint. J Am Soc Nephrol 2002; 13: 3016-3023 (Pubitemid 35386922)
    • (2002) Journal of the American Society of Nephrology , vol.13 , Issue.12 , pp. 3016-3023
    • Pollak, M.R.1
  • 9
    • 16644399642 scopus 로고    scopus 로고
    • Alpha-actinin-4-mediated FSGS: An inherited kidney disease caused by an aggregated and rapidly degraded cytoskeletal protein
    • Yao J, Le TC, Kos CH et al. Alpha-actinin-4-mediated FSGS: an inherited kidney disease caused by an aggregated and rapidly degraded cytoskeletal protein. PLoS Biol 2004; 2: e167
    • (2004) PLoS Biol , vol.2
    • Yao, J.1    Le, T.C.2    Kos, C.H.3
  • 11
    • 58149296225 scopus 로고    scopus 로고
    • Dynamic viscoelasticity of actin cross-linked with wild-type and disease-causing mutant alpha-actinin-4
    • Ward SM, Weins A, Pollak MR et al. Dynamic viscoelasticity of actin cross-linked with wild-type and disease-causing mutant alpha-actinin-4. Biophys J 2008; 95: 4915-4923
    • (2008) Biophys J , vol.95 , pp. 4915-4923
    • Ward, S.M.1    Weins, A.2    Pollak, M.R.3
  • 12
    • 84859498004 scopus 로고    scopus 로고
    • Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors
    • Khurana S, Chakraborty S, Lam M et al. Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors. J Biol Chem2012; 287: 12027-12035
    • (2012) J Biol Chem , vol.287 , pp. 12027-12035
    • Khurana, S.1    Chakraborty, S.2    Lam, M.3
  • 14
    • 84870549921 scopus 로고    scopus 로고
    • Nef interaction with actin compromises human podocyte actin cytoskeletal integrity
    • doi: 10.1016/j.yexmp.2012.06.001
    • Tan R, Patni H, Tandon P et al. Nef interaction with actin compromises human podocyte actin cytoskeletal integrity. Exp Mol Pathol 2012; doi:10.1016/j.yexmp.2012.06.001
    • (2012) Exp Mol Pathol
    • Tan, R.1    Patni, H.2    Tandon, P.3
  • 15
    • 51349162919 scopus 로고    scopus 로고
    • The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A
    • Faul C, Donnelly M, Merscher-Gomez S et al. The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A. Nat Med 2008; 14: 931-938
    • (2008) Nat Med , vol.14 , pp. 931-938
    • Faul, C.1    Donnelly, M.2    Merscher-Gomez, S.3
  • 16
    • 57349158456 scopus 로고    scopus 로고
    • Clinical implications of basic research: Proteinuria and immunity-an over-stated relationship?
    • Mathieson PW. Clinical implications of basic research: proteinuria and immunity-an over-stated relationship?. New Engl J Med 2008; 359: 2492-2494
    • (2008) New Engl J Med , vol.359 , pp. 2492-2494
    • Mathieson, P.W.1
  • 18
    • 84868096177 scopus 로고    scopus 로고
    • α-Actinin-4 is involved in the process by which dexamethasone protects actin cytoskeleton stabilization from adriamycin-induced podocyte injury
    • Liu H, Gao X, Xu H et al. α-Actinin-4 is involved in the process by which dexamethasone protects actin cytoskeleton stabilization from adriamycin-induced podocyte injury. Nephrology (Carlton) 2012; 17: 669-675
    • (2012) Nephrology (Carlton) , vol.17 , pp. 669-675
    • Liu, H.1    Gao, X.2    Xu, H.3
  • 19
    • 80051974905 scopus 로고    scopus 로고
    • Comparison of direct action of thiazolidinediones and glucocorticoids on renal podocytes: Protection from injury and molecular effects
    • Agrawal S, Guess AJ, Benndorf R et al. Comparison of direct action of thiazolidinediones and glucocorticoids on renal podocytes: protection from injury and molecular effects. Mol Pharmacol 2011; 80: 389-399
    • (2011) Mol Pharmacol , vol.80 , pp. 389-399
    • Agrawal, S.1    Guess, A.J.2    Benndorf, R.3
  • 20
    • 80052333245 scopus 로고    scopus 로고
    • Activation of RhoA in podocytes induces focal segmental glomerulosclerosis
    • Zhu L, Jiang R, Aoudjit L et al. Activation of RhoA in podocytes induces focal segmental glomerulosclerosis. J Am Soc Nephrol. 2011; 22: 1621-1630
    • (2011) J Am Soc Nephrol. , vol.22 , pp. 1621-1630
    • Zhu, L.1    Jiang, R.2    Aoudjit, L.3
  • 21
    • 84862777971 scopus 로고    scopus 로고
    • Mechanisms of the proteinuria induced by Rho GTPases
    • Wang L, Ellis MJ, Gomez JA et al. Mechanisms of the proteinuria induced by Rho GTPases. Kidney Int 2012; 81: 1075-1085
    • (2012) Kidney Int , vol.81 , pp. 1075-1085
    • Wang, L.1    Ellis, M.J.2    Gomez, J.A.3
  • 22
    • 84867126616 scopus 로고    scopus 로고
    • Rho-kinase inhibition prevents proteinuria in immune-complex mediated anti-podocyte nephritis
    • Meyer-Schwesinger C, Dehde S, Sachs M et al. Rho-kinase inhibition prevents proteinuria in immune-complex mediated anti-podocyte nephritis. Am J Physiol Renal Physiol 2012; 303: F1015-F1025
    • (2012) Am J Physiol Renal Physiol , vol.303
    • Meyer-Schwesinger, C.1    Dehde, S.2    Sachs, M.3
  • 23
    • 84863534353 scopus 로고    scopus 로고
    • Podocyte-specific loss of cdc42 leads to congenital nephropathy
    • Scott RP, Hawley SP, Ruston J et al. Podocyte-specific loss of cdc42 leads to congenital nephropathy. J Am Soc Nephrol 2012; 23: 1149-1154
    • (2012) J Am Soc Nephrol , vol.23 , pp. 1149-1154
    • Scott, R.P.1    Hawley, S.P.2    Ruston, J.3
  • 24
    • 80053410497 scopus 로고    scopus 로고
    • Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis
    • Akilesh S, Suleiman H, Yu H et al. Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis. J Clin Invest 2011; 121: 4127-4137
    • (2011) J Clin Invest , vol.121 , pp. 4127-4137
    • Akilesh, S.1    Suleiman, H.2    Yu, H.3
  • 25
    • 84875727696 scopus 로고    scopus 로고
    • TNFα pathway blockade ameliorates toxic effects of FSGS plasma on podocyte cytoskeleton and β3 integrin activation
    • Bitzan M, Babayeva S, Vasudevan A et al. TNFα pathway blockade ameliorates toxic effects of FSGS plasma on podocyte cytoskeleton and β3 integrin activation. Pediatr Nephrol 2012; 27: 2217-2226
    • (2012) Pediatr Nephrol , vol.27 , pp. 2217-2226
    • Bitzan, M.1    Babayeva, S.2    Vasudevan, A.3
  • 26
    • 84862832878 scopus 로고    scopus 로고
    • Stimulation of the calciumsensing receptor stabilizes the podocyte cytoskeleton, improves cell survival, and reduces toxin-induced glomerulosclerosis
    • Oh J, Beckmann J, Bloch J et al. Stimulation of the calciumsensing receptor stabilizes the podocyte cytoskeleton, improves cell survival, and reduces toxin-induced glomerulosclerosis. Kidney Int 2011; 80: 483-492
    • (2011) Kidney Int , vol.80 , pp. 483-492
    • Oh, J.1    Beckmann, J.2    Bloch, J.3
  • 27
    • 84856514036 scopus 로고    scopus 로고
    • Acute and sustained actions of hyperglycaemia on endothelial and glomerular barrier permeability
    • Swärd P, Rippe B. Acute and sustained actions of hyperglycaemia on endothelial and glomerular barrier permeability. Acta Physiol (Oxf) 2012; 204: 294-307
    • (2012) Acta Physiol (Oxf) , vol.204 , pp. 294-307
    • Swärd, P.1    Rippe, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.