Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors

Journal of Biological Chemistry

Volumn 287, Issue 15, 2012, Pages 12027-12035

  Khurana, Simran ^a   Chakraborty, Sharmistha ^a   Lam, Minh ^a   Liu, Yu ^a   Su, Yu Ting ^a   Zhao, Xuan ^a   Saleem, Moin A ^c   Mathieson, Peter W ^c   Bruggeman, Leslie A ^b   Kao, Hung Ying ^a  

^a UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN FILAMENT; CYTOSKELETAL ORGANIZATION; ESTROGEN RECEPTOR; GLOMERULOSCLEROSIS; KIDNEY DISEASE; NUCLEAR HORMONE RECEPTOR; NUCLEAR RECEPTORS; OVER-EXPRESSION; PEROXISOME PROLIFERATORS; PODOCYTES; PROTEIN MUTANTS; RETINOIC ACID RECEPTORS; TRANSCRIPTIONAL ACTIVATIONS; TRANSCRIPTIONAL ACTIVITY; WILD TYPES;

ACTIVATION ANALYSIS; CYTOLOGY; TRANSCRIPTION FACTORS;

ENDOCRINOLOGY;

ALPHA ACTININ 4; CELL NUCLEUS RECEPTOR; ESTROGEN RECEPTOR; MYOCYTE ENHANCER FACTOR 2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RETINOIC ACID RECEPTOR;

ACTN4 GENE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; FAMILIAL FOCAL SEGMENTAL GLOMERULOSCLEROSIS; FOCAL GLOMERULOSCLEROSIS; GENE FUNCTION; GENE INTERACTION; GENE OVEREXPRESSION; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; MARKER GENE; PATHOPHYSIOLOGY; PODOCYTE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; WILD TYPE;

ACTININ; CELL LINE; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; HUMANS; MUTANT PROTEINS; MUTATION, MISSENSE; PODOCYTES; PPAR GAMMA; PROTEIN BINDING; PROTEIN TRANSPORT; RECEPTORS, RETINOIC ACID; RECOMBINANT PROTEINS; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; TRETINOIN;

EID: 84859498004     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.345421     Document Type: Article

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