Rapidly-disintegrating sublingual tablets of epinephrine: Role of non-medicinal ingredients in formulation development

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 82, Issue 3, 2012, Pages 598-604

  Rachid, Ousama ^a   Rawas Qalaji, Mutasem ^b   Simons, F Estelle R ^a   Simons, Keith J ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b NOVA SOUTHEASTERN UNIVERSITY   (United States)

Author keywords

Dissolution; Epinephrine; Excipients; Non medicinal ingredients; Rapidly disintegrating tablets; Sublingual administration

Indexed keywords

ADRENALIN; MANNITOL; MICROCRYSTALLINE CELLULOSE;

ARTICLE; BULK DENSITY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG SOLUBILITY; HYDROGEN BOND; IN VITRO STUDY; PARTICLE SIZE; RABBIT; TABLET DISINTEGRATION; TABLET FORMULATION; TABLET POROSITY; WETTABILITY;

ADMINISTRATION, SUBLINGUAL; ANAPHYLAXIS; CELLULOSE; CHEMISTRY, PHARMACEUTICAL; DRUG COMPOUNDING; EPINEPHRINE; EXCIPIENTS; MANNITOL; PARTICLE SIZE; SOLUBILITY; SYMPATHOMIMETICS; TABLETS; TIME FACTORS;

EID: 84870525331     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.05.020     Document Type: Article

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