Epinephrine for the treatment of anaphylaxis: Do all 40 mg sublingual epinephrine tablet formulations with simuilar In Vitro charecteristics have the same bioavailability?

Biopharmaceutics and Drug Disposition

Volumn 27, Issue 9, 2006, Pages 427-435

  Rawas Qalaji, Mutasem M ^a   Simons, F Estelle R ^a   Simons, Keith J ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Adrenaline; Anaphylaxis; Epinephrine; EpiPen; Fast disintegrating tablet; Sublingual absorption

Indexed keywords

ADRENALIN HYDROGEN TARTRATE; CALCIUM SILICATE; CROSPOVIDONE; EXCIPIENT; HYDROXYPROPYLCELLULOSE; MAGNESIUM STEARATE; MANNITOL; MICROCRYSTALLINE CELLULOSE; SILICON DIOXIDE;

ANAPHYLAXIS; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DOSAGE FORM COMPARISON; DRUG MANUFACTURE; DRUG QUALITY; IN VIVO STUDY; NONHUMAN; PROSPECTIVE STUDY; RABBIT; STANDARD; TABLET COMPRESSION; TABLET DISINTEGRATION TIME; TABLET FORMULATION; TABLET FRIABILITY; TABLET HARDNESS; WETTABILITY;

ADMINISTRATION, SUBLINGUAL; ANAPHYLAXIS; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; EPINEPHRINE; RABBITS; TABLETS;

EID: 33846091613     PISSN: 01422782     EISSN: 1099081X     Source Type: Journal    
DOI: 10.1002/bdd.519     Document Type: Article

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