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Volumn 73, Issue 1, 2013, Pages 31-41

Uptake and antitumoral effects of iodine and 6-iodolactone in differentiated and undifferentiated human prostate cancer cell lines

Author keywords

apoptosis; DU 145; LNCaP; proliferation; RWPE 1

Indexed keywords

6 IODOLACTONE; CASPASE 3; IODIDE; IODINE; LACTONE DERIVATIVE; PROTEIN BAX; PROTEIN BCL 2; SODIUM IODIDE SYMPORTER; UNCLASSIFIED DRUG;

EID: 84870501536     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.22536     Document Type: Article
Times cited : (29)

References (50)
  • 2
    • 77951887410 scopus 로고    scopus 로고
    • Multifocal prostate cancer: Biologic, prognostic, and therapeutic implications
    • Andreoiu M, Cheng L. Multifocal prostate cancer: Biologic, prognostic, and therapeutic implications. Hum Pathol 2010;41: 781793.
    • (2010) Hum Pathol , vol.41 , pp. 781793
    • Andreoiu, M.1    Cheng, L.2
  • 3
    • 0041825583 scopus 로고    scopus 로고
    • The thyroid, iodine and breast cancer
    • Smyth PP. The thyroid, iodine and breast cancer. Breast Cancer Res 2003;5:235238.
    • (2003) Breast Cancer Res , vol.5 , pp. 235238
    • Smyth, P.P.1
  • 4
    • 80051705318 scopus 로고    scopus 로고
    • Is iodine an antioxidant and antiproliferative agent for the mammary and prostate glands?
    • San Diego, California: Elsevier
    • Aceves C, Anguiano B. Is iodine an antioxidant and antiproliferative agent for the mammary and prostate glands? In: Preedy VR, Burrow GN, Watson RR, editors. Handbook of iodine. San Diego, California: Elsevier; 2009. pp. 249-257.
    • (2009) Handbook of Iodine , pp. 249-257
    • Aceves, C.1    Anguiano, B.2
  • 6
    • 0002442096 scopus 로고    scopus 로고
    • Hormone synthesis: Thyroid iodine metabolism
    • Braverman LE, Utiger R, editors, Philadelphia, Lippincont: Williams and Wilkins
    • Taurog AM. Hormone synthesis: Thyroid iodine metabolism. In: Braverman LE, Utiger R, editors. The thyroid. A fundamental and clinical text. Philadelphia, Lippincont: Williams and Wilkins; 2000. pp. 6184.
    • (2000) The Thyroid. A Fundamental and Clinical Text , pp. 6184
    • Taurog, A.M.1
  • 7
    • 0025028927 scopus 로고
    • Differences in the distribution of iodine and iodide in the Sprague-Dawley rat
    • Thrall KD, Bull RJ. Differences in the distribution of iodine and iodide in the Sprague-Dawley rat. Fundam Appl Toxicol 1990; 15:7581.
    • (1990) Fundam Appl Toxicol , vol.15 , pp. 7581
    • Thrall, K.D.1    Bull, R.J.2
  • 8
    • 35348996441 scopus 로고    scopus 로고
    • Uptake and gene expression with antitumoral doses of iodine in thyroid and mammary gland: Evidence that chronic administration has no harmful effects
    • Anguiano B, Garcia-Solis P, Delgado G, Aceves VC. Uptake and gene expression with antitumoral doses of iodine in thyroid and mammary gland: Evidence that chronic administration has no harmful effects. Thyroid 2007;17:851859.
    • (2007) Thyroid , vol.17 , pp. 851859
    • Anguiano, B.1    Garcia-Solis, P.2    Delgado, G.3    Aceves, V.C.4
  • 10
    • 67649836744 scopus 로고    scopus 로고
    • The sodium-iodide symporter NIS and pendrin in iodide homeostasis of the thyroid
    • Bizhanova A, Kopp P. The sodium-iodide symporter NIS and pendrin in iodide homeostasis of the thyroid. Endocrinology 2009;150:10841090.
    • (2009) Endocrinology , vol.150 , pp. 10841090
    • Bizhanova, A.1    Kopp, P.2
  • 11
    • 33846819022 scopus 로고    scopus 로고
    • Uptake and antiproliferative effect of molecular iodine in the MCF-7 breast cancer cell line
    • Arroyo-Helguera O, Anguiano B, Delgado G, Aceves C. Uptake and antiproliferative effect of molecular iodine in the MCF-7 breast cancer cell line. Endocr Relat Cancer 2006;13: 11471158.
    • (2006) Endocr Relat Cancer , vol.13 , pp. 11471158
    • Arroyo-Helguera, O.1    Anguiano, B.2    Delgado, G.3    Aceves, C.4
  • 12
    • 0032440846 scopus 로고    scopus 로고
    • Iodine uptake in Laminariales involves extracellular, haloperoxidase-mediated oxidation of iodide
    • Küpper FC, Schweigert N, Ar Gall E, Legendre JM, Vilter H, Kloareg B. Iodine uptake in Laminariales involves extracellular, haloperoxidase-mediated oxidation of iodide. Planta 1998;207:163171.
    • (1998) Planta , vol.207 , pp. 163171
    • Küpper, F.C.1    Schweigert, N.2    Ar Gall, E.3    Legendre, J.M.4    Vilter, H.5    Kloareg, B.6
  • 13
    • 0027143628 scopus 로고
    • Evidence that the inhibitory effects of iodide on thyroid cell proliferation are due to arrest of the cell cycle at G0G1 and G2M phases
    • Smerdely P, Pitsiavas V, Boyages SC. Evidence that the inhibitory effects of iodide on thyroid cell proliferation are due to arrest of the cell cycle at G0G1 and G2M phases. Endocrinology 1993;133:28812888.
    • (1993) Endocrinology , vol.133 , pp. 28812888
    • Smerdely, P.1    Pitsiavas, V.2    Boyages, S.C.3
  • 14
    • 0034464961 scopus 로고    scopus 로고
    • Iodide excess induces apoptosis in thyroid cells through a p53-independent mechanism involving oxidative stress
    • Vitale M, Di Matola, DAscoli F, Salzano S, Bogazzi F, Fenzi G, Martino E, Rossi G. Iodide excess induces apoptosis in thyroid cells through a p53-independent mechanism involving oxidative stress. Endocrinology 2000;141:598605.
    • (2000) Endocrinology , vol.141 , pp. 598605
    • Vitale, M.1    Matola, D.2    D'Ascoli, F.3    Salzano, S.4    Bogazzi, F.5    Fenzi, G.6    Martino, E.7    Rossi, G.8
  • 16
    • 34249661768 scopus 로고    scopus 로고
    • Iodine deficiency activates antioxidant genes and causes DNA damage in the thyroid gland of rats and mice
    • Maier J, van SH, van OC, Paschke R, Weiss RE, Krohn K. Iodine deficiency activates antioxidant genes and causes DNA damage in the thyroid gland of rats and mice. Biochim Biophys Acta 2007;1773:990999.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 990999
    • Maier, J.1    Van, S.H.2    Van, O.C.3    Paschke, R.4    Weiss, R.E.5    Krohn, K.6
  • 17
    • 77949568523 scopus 로고    scopus 로고
    • Iodine induces apoptosis via regulating MAPKs-related p53, p21, and Bcl-xL in thyroid cancer cells
    • Liu XH, Chen GG, Vlantis AC, Tse GM, van Hasselt CA. Iodine induces apoptosis via regulating MAPKs-related p53, p21, and Bcl-xL in thyroid cancer cells. Mol Cell Endocrinol 2010; 320:128135.
    • (2010) Mol Cell Endocrinol , vol.320 , pp. 128135
    • Liu, X.H.1    Chen, G.G.2    Vlantis, A.C.3    Tse, G.M.4    Van Hasselt, C.A.5
  • 18
    • 19444386808 scopus 로고    scopus 로고
    • Inhibition of N-methyl-N-nitrosourea-induced mammary carcinogenesis by molecular iodine (I2) but not by iodide (I-) treatment Evidence that I2 prevents cancer promotion
    • Garcia-Solis P, Alfaro Y, Anguiano B, Delgado G, Guzman RC, Nandi S, Diaz-Munoz M, Vazquez-Martinez O, Aceves C. Inhibition of N-methyl-N- nitrosourea-induced mammary carcinogenesis by molecular iodine (I2) but not by iodide (I-) treatment Evidence that I2 prevents cancer promotion. Mol Cell Endocrinol 2005;236:4957.
    • (2005) Mol Cell Endocrinol , vol.236 , pp. 4957
    • Garcia-Solis, P.1    Alfaro, Y.2    Anguiano, B.3    Delgado, G.4    Guzman, R.C.5    Nandi, S.6    Diaz-Munoz, M.7    Vazquez-Martinez, O.8    Aceves, C.9
  • 19
    • 65649110819 scopus 로고    scopus 로고
    • Antineoplastic effect of iodine in mammary cancer: Participation of 6-iodolactone (6-IL) and peroxisome proliferator-activated receptors (PPAR)
    • Aceves C, Garcia-Solis P, Arroyo-Helguera O, Vega-Riveroll L, Delgado G, Anguiano B. Antineoplastic effect of iodine in mammary cancer: Participation of 6-iodolactone (6-IL) and peroxisome proliferator-activated receptors (PPAR). Mol Cancer 2009;8:33.
    • (2009) Mol Cancer , vol.8 , pp. 33
    • Aceves, C.1    Garcia-Solis, P.2    Arroyo-Helguera, O.3    Vega-Riveroll, L.4    Delgado, G.5    Anguiano, B.6
  • 21
    • 47349125602 scopus 로고    scopus 로고
    • Iodine alters gene expression in the MCF7 breast cancer cell line: Evidence for an anti-estrogen effect of iodine
    • Stoddard FR, Brooks AD, Eskin BA, Johannes GJ. Iodine alters gene expression in the MCF7 breast cancer cell line: Evidence for an anti-estrogen effect of iodine. Int J Med Sci 2008;5:189 196.
    • (2008) Int J Med Sci , vol.5 , pp. 189-196
    • Stoddard, F.R.1    Brooks, A.D.2    Eskin, B.A.3    Johannes, G.J.4
  • 23
    • 80051765578 scopus 로고    scopus 로고
    • Antineoplastic effect of iodine and iodide in dimethylbenz[a]anthracene- induced mammary tumors: Association between lactoperoxidase and estrogenadduct production
    • Soriano O, Delgado G, Anguiano B, Petrosyan P, Molina-Serv?́n ED, Gonsebatt ME, Aceves C. Antineoplastic effect of iodine and iodide in dimethylbenz[a]anthracene-induced mammary tumors: Association between lactoperoxidase and estrogenadduct production. Endocr Relat Cancer 2011;18:529539.
    • (2011) Endocr Relat Cancer , vol.18 , pp. 529539
    • Soriano, O.1    Delgado, G.2    Anguiano, B.3    Petrosyan, P.4    Molina-Servn, E.D.5    Gonsebatt, M.E.6    Aceves, C.7
  • 24
    • 58249112933 scopus 로고    scopus 로고
    • Signaling pathways involved in the antiproliferative effect of molecular iodine in normal and tumoral breast cells: Evidence that 6- iodolactone mediates apoptotic effects
    • Arroyo-Helguera O, Rojas E, Delgado G, Aceves C. Signaling pathways involved in the antiproliferative effect of molecular iodine in normal and tumoral breast cells: Evidence that 6- iodolactone mediates apoptotic effects. Endocr Relat Cancer 2008;15:10031011.
    • (2008) Endocr Relat Cancer , vol.15 , pp. 10031011
    • Arroyo-Helguera, O.1    Rojas, E.2    Delgado, G.3    Aceves, C.4
  • 25
    • 34447540132 scopus 로고    scopus 로고
    • A prospective study of iodine status, thyroid function, and prostate cancer risk: Follow-up of the First National Health and Nutrition Examination Survey
    • Hoption Cann SA, Qiu Z, van NC. A prospective study of iodine status, thyroid function, and prostate cancer risk: Follow- up of the First National Health and Nutrition Examination Survey. Nutr Cancer 2007;58:2834.
    • (2007) Nutr Cancer , vol.58 , pp. 2834
    • Hoption Cann, S.A.1    Qiu, Z.2    Van, N.C.3
  • 26
    • 0031723728 scopus 로고    scopus 로고
    • Analysis of human sodium iodide symporter gene expression in extrathyroidal tissues and cloning of its complementary deoxyribonucleic acids from salivary gland, mammary gland, and gastric mucosa
    • Spitzweg C, Joba W, Eisenmenger W, Heufelder AE. Analysis of human sodium iodide symporter gene expression in extrathyroidal tissues and cloning of its complementary deoxyribonucleic acids from salivary gland, mammary gland, and gastric mucosa. J Clin Endocrinol Metab 1998;83:17461751.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 17461751
    • Spitzweg, C.1    Joba, W.2    Eisenmenger, W.3    Heufelder, A.E.4
  • 28
    • 0034913576 scopus 로고    scopus 로고
    • Cloning of the mouse sodium iodide symporter and its expression in the mammary gland and other tissues
    • Perron B, Rodriguez AM, Leblanc G, Pourcher T. Cloning of the mouse sodium iodide symporter and its expression in the mammary gland and other tissues. J Endocrinol 2001;170:185196.
    • (2001) J Endocrinol , vol.170 , pp. 185-196
    • Perron, B.1    Rodriguez, A.M.2    Leblanc, G.3    Pourcher, T.4
  • 29
    • 0037683589 scopus 로고    scopus 로고
    • Immunohistochemical profile of the sodium/iodide symporter in thyroid, breast, and other carcinomas using high density tissue microarrays and conventional sections
    • Wapnir IL, van de Rijn M, Nowels K, Amenta PS, Walton K, Montgomery K, Greco RS, Dohan O, Carrasco N. Immunohistochemical profile of the sodium/iodide symporter in thyroid, breast, and other carcinomas using high density tissue microarrays and conventional sections. J Clin Endocrinol Metab 2003;88:18801888.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 18801888
    • Wapnir, I.L.1    Van De Rijn, M.2    Nowels, K.3    Amenta, P.S.4    Walton, K.5    Montgomery, K.6    Greco, R.S.7    Dohan, O.8    Carrasco, N.9
  • 31
    • 0347412916 scopus 로고
    • The rate of oxidation of iodide ion by hydrogen peroxide
    • McAlpine RK. The rate of oxidation of iodide ion by hydrogen peroxide. J Chem Educ 1945;22:387390.
    • (1945) J Chem Educ , vol.22 , pp. 387390
    • McAlpine, R.K.1
  • 32
    • 84870557540 scopus 로고
    • Evaluation of the trypan blue technique for determination of cell viability
    • Tennant JR. Evaluation of the trypan blue technique for determination of cell viability. Transplantation 1964;2:685694.
    • (1964) Transplantation , vol.2 , pp. 685694
    • Tennant, J.R.1
  • 33
    • 33751088303 scopus 로고    scopus 로고
    • Enhancement of sodium/iodide symporter expression in thyroid and breast cancer
    • Kogai T, Taki K, Brent GA. Enhancement of sodium/iodide symporter expression in thyroid and breast cancer. Endocr Relat Cancer 2006;13:797826.
    • (2006) Endocr Relat Cancer , vol.13 , pp. 797826
    • Kogai, T.1    Taki, K.2    Brent, G.A.3
  • 34
    • 33846956102 scopus 로고    scopus 로고
    • Expression of the Na/I- symporter (NIS) is markedly decreased or absent in gastric cancer and intestinal metaplastic mucosa of Barrett esophagus
    • Altorjay A, Dohan O, Szilagyi A, Paroder M, Wapnir IL, Carrasco N. Expression of the Na/I- symporter (NIS) is markedly decreased or absent in gastric cancer and intestinal metaplastic mucosa of Barrett esophagus. BMC Cancer 2007;7:5.
    • (2007) BMC Cancer , vol.7 , pp. 5
    • Altorjay, A.1    Dohan, O.2    Szilagyi, A.3    Paroder, M.4    Wapnir, I.L.5    Carrasco, N.6
  • 35
    • 0041814617 scopus 로고    scopus 로고
    • Retinoic acid-induced stimulation of sodium iodide symporter expression and cytotoxicity of radioiodine in prostate cancer cells
    • Spitzweg C, Scholz IV, Bergert ER, Tindall DJ, Young CY, Goke B, Morris JC. Retinoic acid-induced stimulation of sodium iodide symporter expression and cytotoxicity of radioiodine in prostate cancer cells. Endocrinology 2003;144:34233432.
    • (2003) Endocrinology , vol.144 , pp. 34233432
    • Spitzweg, C.1    Scholz, I.V.2    Bergert, E.R.3    Tindall, D.J.4    Young, C.Y.5    Goke, B.6    Morris, J.C.7
  • 36
    • 0141864361 scopus 로고    scopus 로고
    • Pendrin transporter carries out iodide uptake into MCF-7 human mammary cancer cells
    • Rillema JA, Hill MA. Pendrin transporter carries out iodide uptake into MCF-7 human mammary cancer cells. Exp Biol Med 2003;228:10781082.
    • (2003) Exp Biol Med , vol.228 , pp. 10781082
    • Rillema, J.A.1    Hill, M.A.2
  • 37
    • 77954876358 scopus 로고    scopus 로고
    • Antiproliferative/ cytotoxic activity of molecular iodine and iodolactones in various human carcinoma cell lines. No interfering with EGFsignaling, but evidence for apoptosis
    • Rosner H, Torremante P, Moller W, Gartner R. Antiproliferative/ cytotoxic activity of molecular iodine and iodolactones in various human carcinoma cell lines. No interfering with EGFsignaling, but evidence for apoptosis. Exp Clin Endocrinol Diabetes 2010;118:410419.
    • (2010) Exp Clin Endocrinol Diabetes , vol.118 , pp. 410419
    • Rosner, H.1    Torremante, P.2    Moller, W.3    Gartner, R.4
  • 38
    • 77049103352 scopus 로고    scopus 로고
    • Effects of high-dose major components in oral disinfectants on the cell cycle and apoptosis in primary human gingival fibroblasts in vitro
    • Nomura Y, Bhawal UK, Nishikiori R, Sawajiri M, Maeda T, Okazaki M. Effects of high-dose major components in oral disinfectants on the cell cycle and apoptosis in primary human gingival fibroblasts in vitro. Dent Mater J 2010;29:7583.
    • (2010) Dent Mater J , vol.29 , pp. 7583
    • Nomura, Y.1    Bhawal, U.K.2    Nishikiori, R.3    Sawajiri, M.4    Maeda, T.5    Okazaki, M.6
  • 41
    • 70449362071 scopus 로고    scopus 로고
    • High iodine concentration attenuates RET/PTC3 oncogene activation in thyroid follicular cells
    • Fiore AP, Fuziwara CS, Kimura ET. High iodine concentration attenuates RET/PTC3 oncogene activation in thyroid follicular cells. Thyroid 2009;19:12491256.
    • (2009) Thyroid , vol.19 , pp. 12491256
    • Fiore, A.P.1    Fuziwara, C.S.2    Kimura, E.T.3
  • 42
    • 0028172325 scopus 로고
    • Identification of delta-iodolactone in iodide treated human goiter and its inhibitory effect on proliferation of human thyroid follicles
    • Dugrillon A, Uedelhoven WM, Pisarev MA, Bechtner G, Gartner R. Identification of delta-iodolactone in iodide treated human goiter and its inhibitory effect on proliferation of human thyroid follicles. Horm Metab Res 1994;26:465469.
    • (1994) Horm Metab Res , vol.26 , pp. 465469
    • Dugrillon, A.1    Uedelhoven, W.M.2    Ma, P.3    Bechtner, G.4    Gartner, R.5
  • 43
    • 77950436724 scopus 로고    scopus 로고
    • The role of iodine and delta-iodolactone in growth and apoptosis of malignant thyroid epithelial cells and breast cancer cells
    • Gartner R, Rank P, Ander B. The role of iodine and delta-iodolactone in growth and apoptosis of malignant thyroid epithelial cells and breast cancer cells. Hormones 2010;9:6066.
    • (2010) Hormones , vol.9 , pp. 6066
    • Gartner, R.1    Rank, P.2    Ander, B.3
  • 44
    • 65649112487 scopus 로고    scopus 로고
    • A complex between 6-iodolactone and the peroxisome proliferator-activated receptor type gamma may mediate the antineoplastic effect of iodine in mammary cancer
    • Nuñez-Anita RE, Arroyo-Helguera O, Cajero-Juarez M, Lopez- Bojorquez L, Aceves C. A complex between 6-iodolactone and the peroxisome proliferator-activated receptor type gamma may mediate the antineoplastic effect of iodine in mammary cancer. Prostaglandins Other Lipid Mediat 2009; 89:3442.
    • (2009) Prostaglandins Other Lipid Mediat , vol.89 , pp. 3442
    • Nuñez-Anita, R.E.1    Arroyo-Helguera, O.2    Cajero-Juarez, M.3    Lopez-Bojorquez, L.4    Aceves, C.5
  • 46
    • 0030006530 scopus 로고    scopus 로고
    • Increased phospholipid fatty acid remodeling in human and rat prostatic adenocarcinoma tissues
    • Faas FH, Dang AQ, Pollard M, Hong XM, Fan K, Luckert PH, Schutz M. Increased phospholipid fatty acid remodeling in human and rat prostatic adenocarcinoma tissues. J Urol 1996; 156:243248.
    • (1996) J Urol , vol.156 , pp. 243248
    • Faas, F.H.1    Dang, A.Q.2    Pollard, M.3    Hong, X.M.4    Fan, K.5    Luckert, P.H.6    Schutz, M.7
  • 47
    • 80051678549 scopus 로고    scopus 로고
    • Peroxisome proliferator- activated receptors. role of isoform gamma in the antineoplastic effect of iodine in mammary cancer
    • Nuñez-Anita RE, Cajero-Juárez M, Aceves C. Peroxisome proliferator- activated receptors. role of isoform gamma in the antineoplastic effect of iodine in mammary cancer. Curr Cancer Drug Targets 2011;11:775786.
    • (2011) Curr Cancer Drug Targets , vol.11 , pp. 775786
    • Nuñez-Anita, R.E.1    Cajero-Juárez, M.2    Aceves, C.3
  • 48
    • 33845775283 scopus 로고    scopus 로고
    • Iodide excess exerts oxidative stress in some target tissues of the thyroid hormones
    • Joanta AE, Filip A, Clichici S, Andrei S, Daicoviciu D. Iodide excess exerts oxidative stress in some target tissues of the thyroid hormones. Acta Physiol Hung 2006;93:347359.
    • (2006) Acta Physiol Hung , vol.93 , pp. 347359
    • Joanta, A.E.1    Filip, A.2    Clichici, S.3    Andrei, S.4    Daicoviciu, D.5
  • 49
    • 0034468546 scopus 로고    scopus 로고
    • Effects of iodine on inducible nitric oxide synthase and cyclooxygenase-2 expression in sulfur mustard- induced skin
    • Nyska A, Lomnitski L, Maronpot R, Moomaw C, Brodsky B, Sintov A, Wormser U. Effects of iodine on inducible nitric oxide synthase and cyclooxygenase-2 expression in sulfur mustard- induced skin. Arch Toxicol 2001;74:768774.
    • (2001) Arch Toxicol , vol.74 , pp. 768774
    • Nyska, A.1    Lomnitski, L.2    Maronpot, R.3    Moomaw, C.4    Brodsky, B.5    Sintov, A.6    Wormser, U.7
  • 50
    • 0034646193 scopus 로고    scopus 로고
    • The action of soybean lipoxygenase-1 on 12-iodo-cis-9-octadecenoic acid: The importance of C11-H bond breaking
    • Clapp CH, McKown J, Xu H, Grandizio AM, Yang G, Fayer J. The action of soybean lipoxygenase-1 on 12-iodo-cis-9-octadecenoic acid: The importance of C11-H bond breaking. Biochemistry 2000;39:26032611.
    • (2000) Biochemistry , vol.39 , pp. 26032611
    • Clapp, C.H.1    McKown, J.2    Xu, H.3    Grandizio, A.M.4    Yang, G.5    Fayer, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.