Multiplex detection of protein toxins using MALDI-TOF-TOF tandem mass spectrometry: Application in unambiguous toxin detection from bioaerosol

Analytical Chemistry

Volumn 84, Issue 23, 2012, Pages 10500-10507

  Alam, Syed Imteyaz ^a   Kumar, Bhoj ^a   Kamboj, Dev Vrat ^a  

^a DEFENCE RESEARCH AND DEVELOPMENT ESTABLISHMENT   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BIOAEROSOLS; BIOINFORMATIC ANALYSIS; BOTULINUM NEUROTOXINS; CLOSTRIDIUM PERFRINGENS; EPSILON TOXINS; GEOGRAPHICAL LOCATIONS; HIGH CONFIDENCE; MALDI-TOF-TOF; MEDICAL COUNTERMEASURES; PEPTIDE SEQUENCES; PHOSPHOLIPASE C; PLANT TOXINS; PROOF OF CONCEPT; PROTEIN DATABASE; PROTEIN MIXTURES; PROTEIN TOXINS; SAMPLE PROCESSING; SHIGA TOXIN; SPIKED SAMPLES; STAPHYLOCOCCAL ENTEROTOXIN B; TANDEM MASS SPECTROMETRY; TANDEM MS; TOXIN DETECTION;

AEROSOLS; BIOINFORMATICS; BIOTECHNOLOGY; BIOTERRORISM; CONSERVATION; MASS SPECTROMETRY; METABOLITES; MULTIPLEXING; PEPTIDES; SEARCH ENGINES; STORMS;

TOXIC MATERIALS;

BACTERIAL TOXIN; BIOLOGICAL MARKER; BOTULINUM TOXIN; CLOSTRIDIUM PERFRINGENS EPSILON TOXIN; CLOSTRIDIUM PERFRINGENS EPSILON-TOXIN; ENTEROTOXIN; ENTEROTOXIN B, STAPHYLOCOCCAL; PEPTIDE FRAGMENT; RICIN;

AEROSOL; ARTICLE; BIOLOGY; CHEMISTRY; CLOSTRIDIUM; HUMAN; MASS SPECTROMETRY; METHODOLOGY; TANDEM MASS SPECTROMETRY;

AEROSOLS; BACTERIAL TOXINS; BIOLOGICAL MARKERS; BOTULINUM TOXINS; CLOSTRIDIUM; COMPUTATIONAL BIOLOGY; ENTEROTOXINS; HUMANS; PEPTIDE FRAGMENTS; RICIN; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84870489673     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac3028678     Document Type: Article

References (31)

1. Arnon, S. S.; Schechter, R.; Inglesby, T. V.; Henderson, D. A.; Bartlett, J. G.; Ascher, M. S.; Eitzen, E.; Fine, A. D.; Hauer, J.; Layton, M.; Lillibridge, S.; Osterholm, M. T.; O'Toole, T.; Parker, G.; Perl, T. M.; Russell, P. K.; Swerdlow, D. L.; Tonat, K. JAMA 2001, 285, 1059-1070
2. Brown, M. B.; Savva, C. G.; da Costa, S. P. F.; Naylor, C. E.; Basak, A. K.; Titball, R. W. FEBS J. 2011, 278, 4589-4601
3. Popoff, M. R. FEBS J. 2011, 278, 4602-4615
4. Franz, D. R.; Jaax, N. K. In Medical Aspects of Chemical and Biological Warfare; Borden Institute, Walter Reed Army Medical Center: Washington, DC, 1997; pp 631-642.
5. Awad, M. M.; Bryant, A. F.; Stevens, D. L.; Rood, J. I. Mol. Microbiol. 1995, 15, 191-202
6. MacLennan, J. D. Lancet 1943, ii, 123-126
7. Griffiths, G. D.; Newman, H.; Gee, D. J. J. Forensic Sci. Soc. 1986, 26, 349-358
8. Shyu, H. F.; Chiao, D. J.; Liu, H.; Tang, S. S. Hybridoma Hybridomics 2002, 21, 69-73
9. Sasaki, T.; Terano, Y.; Shibata, T.; Kawamoto, H.; Kuzuguchi, T.; Kohyama, E.; Watanabe, T.; Ohyama, T.; Gemba, M. Microbiol. Immunol. 2005, 49, 589-597
10. Pauly, D.; Kirchner, S.; Stoermann, B.; Schreiber, T.; Kaulfuss, S.; Schade, R.; Zbinden, R.; Avondet, M. A.; Dorner, M. B.; Dorner, B. G. Analyst 2009, 134, 2028-2039
11. Soelberg, S. D.; Stevens, R. C.; Limaye, A. P.; Furlong, C. E. Anal. Chem. 2009, 81, 2357-2363
12. van Baar, B. L. M.; Hulst, A. G.; Roberts, B.; Wils, E. R. J. Anal. Biochem. 2002, 301, 278-289
13. Hines, H. B.; Lebeda, F.; Hale, M.; Brueggemann, E. E. Appl. Environ. Microbiol. 2005, 71 (8) 4478-4486
14. Callahan, J. H.; Shefcheck, K. J.; Williams, T. L.; Musser, S. M. Anal. Chem. 2006, 78, 1789-1800
15. Dupuis, A.; Hennekinne, J. A.; Garin, J.; Brun, V. Proteomics 2008, 8, 4633-4636
16. Duriez, E.; Fenaille, F.; Tabet, J. C.; Lamourette, P.; Hilaire, D.; Becher, F.; Ezan, E. J. Proteome. Res. 2008, 7, 4154-4163
17. Duriez, E.; Goossens, P. L.; Becher, F.; Ezan, E. Anal. Chem. 2009, 81, 5935-5941
18. Kalb, S. R.; Barr, R. Anal. Chem. 2009, 81, 2037-2042
19. Kull, S.; Pauly, D.; Störmann, B.; Kirchner, S.; Stämmler, M.; Dorner, M. B.; Lasch, P.; Naumann, D.; Dorner, B. G. Anal. Chem. 2010, 82, 2916-2924
20. McGrath, S. C.; Schieltz, D. M.; McWilliams, L. G.; Pirkle, J. L.; Barr, J. R. Anal. Chem. 2011, 83, 2897-2905
21. Seyer, A.; Fenaille, F.; Féraudet-Tarisse, C.; Volland, H.; Popoff, M. R.; Tabet, J. C.; Junot, C.; Becher, F. Anal. Chem. 2012, 84, 5103-5109
22. Gallien, S.; Duriez, E.; Domon, B. J. Mass Spectrom. 2011, 46, 298-312
23. Norrgran, J.; Williams, T. L.; Woolfitt, A. R.; Solano, M. I.; Pirkle, J. L.; Barr, J. R. Anal. Biochem. 2009, 393, 48-55
24. Barr, J. R.; Moura, H.; Boyer, A. E.; Woolfitt, A. R.; Kalb, S. R.; Pavlopoulos, A.; McWilliams, L.; Schmidt, J. G.; Martinez, R. A.; Ashley, D. L. Emerging Infect. Dis. 2005, 11, 1578-1583
25. Williams, J. P.; Green, B. N.; Smith, D. C.; Jennings, K. R.; Moore, K. A. H.; Slade, S. E.; Roberts, L. M.; Scrivens, J. H. Biochemistry 2005, 44, 8282-8290
26. Speicher, K; Kolbas, O.; Harper, S.; Speicher, D. W. J. Biomol. Tech. 2000, 11, 74-86
27. Xia, X.; Xie, Z. D. J. Hered. 2001, 92, 371-373
28. Ecker, D. J.; Sampath, R.; Willett, P.; Wyatt, J. R.; Samant, V.; Massire, C.; Hall, T. A.; Hari, K.; McNeil, J. A.; Büchen-Osmond, C.; Budowle, B. BMC Microbiol. 2005, 5, 19
29. Russell, W. K.; Park, Z.-Y.; Russell, D. H. Anal. Chem. 2001, 73, 2682-2685
30. Proc, J. L.; Kuzyk, M. A.; Hardie, D. B.; Yang, J.; Smith, D. S.; Jackson, A. M.; Parker, C. E.; Borchers, C. H. J. Proteome Res. 2010, 9 (10) 5422-5437
31. Norrgran, J.; Williams, T. L.; Woolfitt, A. R.; Solano, M. I.; Pirkle, J. L.; Barr, J. R. Anal. Biochem. 2009, 393, 48-55