Heat shock protein 70 selectively mediates the degradation of cytosolic PrPs and restores the cytosolic PrP-induced cytotoxicity via a molecular interaction

Virology Journal

Volumn 9, Issue , 2012, Pages

  Zhang, Jin ^a   Wang, Ke ^a   Guo, Yan ^a   Shi, Qi ^a   Tian, Chan ^a   Chen, Cao ^a   Gao, Chen ^a   Zhang, Bao Yun ^a   Dong, Xiao Ping ^a,b  

^a CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^b INSTITUTE OF MICROBIOLOGY   (China)

Author keywords

Apoptosis; Cytosolic PrP; Geldanamycin; Hsp70; Prion disease

Indexed keywords

GELDANAMYCIN; HEAT SHOCK PROTEIN 70; PRION PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; ASSAY; CELL CULTURE; CELL STRAIN HEK293; CYTOSOL; CYTOTOXICITY; ENDOPLASMIC RETICULUM; GENETIC TRANSFECTION; HAMSTER; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MOLECULAR INTERACTION; NONHUMAN; PLASMID; PRION DISEASE; PROTEIN LOCALIZATION; UPREGULATION; WESTERN BLOTTING; WILD TYPE;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL LINE; CRICETINAE; CYTOSOL; HSP70 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOPRECIPITATION; MESOCRICETUS; PRIONS; PROTEIN BINDING; PROTEIN INTERACTION MAPPING;

CRICETINAE; MUS MUSCULUS;

EID: 84870412378     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-9-303     Document Type: Article

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