Amelioration of chemical-induced skin carcinogenesis by aegle marmelos, an Indian medicinal plant, fruit extract

Integrative Cancer Therapies

Volumn 11, Issue 3, 2012, Pages 257-266

  Agrawal, Annapurna ^a   Jahan, Swafiya ^a   Soyal, Dhanraj ^a   Goyal, Ekank ^b   Goyal, Pradeep Kumar ^a  

^a UNIVERSITY OF RAJASTHAN   (India)

^b VIT UNIVERSITY   (India)

Author keywords

Aegle marmelos; antioxidants; chemoprevention; lipid peroxidation; skin papillomas; Swiss albino mice

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; AEGLE MARMELOS EXTRACT; ASCORBIC ACID; CATALASE; GLUTATHIONE; SUPEROXIDE DISMUTASE;

AEGLE MARMELOS; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BODY WEIGHT; CANCER INCIDENCE; CHEMOPROPHYLAXIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; FRUIT; LATENT PERIOD; LIPID PEROXIDATION; LIVER; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SKIN; SKIN CARCINOGENESIS; TREATMENT DURATION; TUMOR VOLUME;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ADMINISTRATION, ORAL; AEGLE; ANIMALS; ANTIOXIDANTS; DISEASE MODELS, ANIMAL; INDIA; LIPID PEROXIDATION; LIVER; MALE; MICE; OXIDATIVE STRESS; PAPILLOMA; PLANT EXTRACTS; SKIN NEOPLASMS; TUMOR BURDEN;

EID: 84870400923     PISSN: 15347354     EISSN: 1552695X     Source Type: Journal    
DOI: 10.1177/1534735411417127     Document Type: Article

References (38)

1. Armstrong BK, Kricker A. The epidemiology of UV induced skin cancer. J Photochem Photobiol B. 2001 ; 63: 8-18 (Pubitemid 33040718)
2. Kaneko M, Morimura K, Nishikawa T, et al. Different genetic alterations in rat forestomach tumors induced by genotoxic and non-genotoxic carcinogens. Carcinogenesis. 2002 ; 23: 1729-1735 (Pubitemid 35214959)
3. Mahadeven B, Luch A, Bravo CF, et al. Dibenzo(a,I) pyrene induced DNA adduct formation in lung tissue in vivo. Cancer Lett. 2005 ; 227: 25-32 (Pubitemid 41033089)
4. Raha S, Robinson BH. Mitochondria, oxygen free radicals, disease and ageing. Trends Biochem Sci. 2000 ; 25: 502-508
5. Selek S, Herken H, Bulut M, et al. Oxidative imbalance in obsessive compulsive disorder patients: a total evaluation of oxidant-antioxidant status. Prog Neuropsychopharmacol Biol Psychiatry. 2008 ; 32: 487-491 (Pubitemid 351187832)
6. Arber N, Levin B. Chemoprevention of colorectal cancer: ready for routine use?. Curr Top Med Chem. 2005 ; 5: 517-525 (Pubitemid 40974823)
7. Weiss JF, Landauer MR. Protection against ionizing radiation by antioxidant nutrients and phytochemicals. Toxicology. 2003 ; 189: 1-20 (Pubitemid 36725020)
8. Abdullaev FI Pharmacology and Therapeutics in the New Millennium. Gupta SK, ed. New Delhi, India: Narosa ; 2001: 345-354.
9. Sharma RK, Bhagwan D Agnivesa's Charaka Samhita. Varanasi, India: Chaukhambha Orientalia ; 1988 :
10. Selected Medicinal Plant of India. Mumbai, India: Basic Chemicals, Pharmaceutical and Cosmetic Export Promotion Council ; 1992: 205-207.
11. Miyazaki S, Ranganathan D, Kadarkariswami M. Elucidation of toxicity of the A. marmelos. Phytomedicine. 2007 ; 4: 204-205
12. Kamalakkanan N, Rajadurai M, Prince PS. Effect of Aegle marmelos fruits on normal and streptozotocin-diabetic Wistar rats. J Med Food. 2003 ; 6: 93-98 (Pubitemid 37128469)
13. Citarasu T, Sivaram V, Immanuel G, Rout N, Murugan V. Influence of selected Indian immunostimulant herbs against white spot syndrome virus (WSSV) infection in black tiger shrimp, Penaeus monodon with reference to haematological, biochemical and immunological changes. Fish Shellfish Immunol. 2006 ; 4: 372-384
14. Ohkhawa H, Ohishi N, Yogi K. Assay for lipid peroxidation in animal tissue by thiobarbituric acid reaction. Anal Biochem. 1979 ; 5: 351-358 (Pubitemid 9194347)
15. Moron MA, Depierre JW, Mannervick B. Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver. Biochem Biophys Acta. 1979 ; 582: 67-78 (Pubitemid 9065588)
16. Marklund S, Marklund G. Involvement of the superoxide anion radical in autooxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem. 1974 ; 47: 469-474
17. Aebi H Methods in Enzymology. Colowick SP Kaplan NO, ed. New York, NY: Academic Press ; 1984: 121-126.
18. Roe JH, Kuether CA. The determination of ascorbic acid in whole blood and urine through the 2,4-dinitrophenylhydrazine derivative of dehydro ascorbic acid. J Biol Chem. 1943 ; 147: 399-407
19. Lowry OH, Rosenbrough NJ, Farr AL, Landall AJ. Protein estimation with Folin phenol reagent. J Biol Chem. 1951 ;: 193-265
20. Harris CC. Future directions in use of DNA adducts as internal dosimeters for monitoring human exposure to environmental mutagens and carcinogens. Environ Health Perspect. 1985 ; 62: 185-191 (Pubitemid 16188421)
21. Swenberg JA, Richardson FC, Boucheron JA, Dyroff MC. Relationship between DNA adduct formation and carcinogenesis. Environ Health Perspect. 1985 ; 62: 177-183 (Pubitemid 16188420)
22. Ames BN, Shigenaga MK, Hagen TM. Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci U S A. 1993 ; 90: 7915-7922 (Pubitemid 23260825)
23. Hanausek M, Walaszek Z, Slaga TJ. Detoxifying cancer causing agents to prevent cancer. Integr Cancer Ther. 2003 ; 2: 139-144 (Pubitemid 37322458)
24. Sun Y. Free radicals, antioxidant enzymes, and carcinogenesis. Free Radic Biol Med. 1990 ; 8: 583-599 (Pubitemid 20204421)
25. Chow CK Cellular Antioxidant Defense Mechanism II. Chow CK, ed. Boca Raton, FL: CRC Press ; 1988: 217-237.
26. Singh RP, Padmanathi B, Rao AR. Modulatory influence of Adhatoda vesica (Justicia adhatoda) leaf extract on the enzymes of xenobiotics metabolism antioxidant status and lipid peroxidation in mice. Mol Cell Biochem. 2000 ; 213: 99-109
27. Perchellet JP, Perchellet M. Antioxidant and multistage carcinogenesis in mouse skin. Free Radic Biol Med. 1989 ; 7: 377-408
28. Lewine WG. Glutathione, lipid peroxidation and regulation of cyt P-450 activity. Life Sci. 1982 ; 31: 779-784
29. Kausar H, Bhasin G, Zargar MA, Ather M. Palm oil alleviates 12-O-tetradecanoyl-phorbol-13 acetate-induced tumor promotion response in murin skin. Cancer Lett. 2003 ; 192: 151-160 (Pubitemid 36369269)
30. Sancheti G, Jindal A, Kumari R, Goyal PK. Chemoprotective action of Emblica officinalis on skin carcinogenesis in mice. Asia Pac J Cancer Prev. 2005 ; 6: 197-201
31. Kumar M, Soni KA, Shukla S, Kumar A. Chemopreventive potential of Tribulus terrestis against 7,12 dimethylbenz (a) anthracene induced skin papillomagenesis in mice. Asia Pac J Cancer Prev. 2006 ; 7: 289-294
32. Li S, Yan T, Yang JQ, Oberley TD, Oberley LW. The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase. Cancer Res. 2000 ; 60: 3927-3939 (Pubitemid 32204589)
33. Chaudhary R, Jahan S, Goyal PK. Chemopreventive potential of an Indian medicinal plant (Tinospora cordifolia) on skin carcinogenesis. J Environ Pathol Toxicol Oncol. 2008 ; 27: 233-243
34. Marvish SS Cancer Achievements, Challenges and Prospects for the 1980s. Burchenal JH Oettgenal HF, ed. New York, NY: Grune & Strtton ; 1981: 557-588.
35. Sinha R, Kiley SC, Lu JX, et al. Effects of methylselenocysteine on PKC activity, cdk2 phosphorylation and gad gene expression in synchronized mouse mammary epithelial tumor cells. Cancer Lett. 1999 ; 146: 135-145 (Pubitemid 29492882)
36. Kamalakannan N, Stanely MainzenPrince P. Effect of Aegle marmelos Correa. (Bael) fruit extract on tissue antioxidants in streptozotocin diabetic rats. Indian J Exp Biol. 2003 ; 41: 1285-1288
37. Nadkarni KM Indian Materia Medica. Mumbai, India: Popular Prakashan ; 1992: 45-82.
38. Rastogi RP, Mehrotra BN Compendium of Indian Medicinal Plants. New Delhi, India: Publication and Information Directorate ; 1991: 17-32.