Gastroprotective effect of the ethanolic extract and fractions obtained from syngonanthus bisulcatus Rul

Records of Natural Products

Volumn 7, Issue 1, 2013, Pages 35-44

  Batista, Leônia Maria ^a   de Almeida, Ana Beatriz Albino ^b   Lima, Gedson Rodrigues de Morais ^a   Falcão, Heloina de Sousa ^b   Ferreira, Anderson Luiz ^b   Magri, Luciana de Pietro ^b   Coelho, Roberta Gomes ^c   Calvo, Tamara Regina ^c   Vilegas, Wagner ^c   Brito, Alba Regina Monteiro Souza ^b  

^a FEDERAL UNIVERSITY OF PARAÍBA   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

^c SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Eriocaulaceae; Gastric ulcer; Gastroprotective activity; Medicinal plants; Syngonanthus bisulcatus

Indexed keywords

ANTIULCER AGENT; CIMETIDINE; LANSOPRAZOLE; PLANT EXTRACT; PROSTAGLANDIN E2; SYNGONANTHUS BISULCATUS EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG SCREENING; ERIOCAULACEAE; MALE; MOUSE; NONHUMAN; PHYTOCHEMISTRY; RAT; STOMACH JUICE; STOMACH MUCOSA; STOMACH PROTECTION; STOMACH ULCER; SYNGONANTHUS BISULCATUS;

ERIOCAULACEAE; MUS; RATTUS; SYNGONANTHUS;

EID: 84870387349     PISSN: None     EISSN: 13076167     Source Type: Journal    
DOI: None     Document Type: Article

References (60)

1. H.E. Vonkeman, R. M. Klok, M. J. Postma, J. R. Brouwers, M. A. Van de Laar (2007). Direct medical costs of serious gastrointestinal ulcers among users of NSAID, Drugs Aging 24: 681-690.
2. S. Alqasoumi, M. Al-Sohaibani, T. Al-Howiriny, M. Al-Yahya, S. Rafatullah (2009). Rocket Eruca sativa: a salad herb with potential gastric anti-ulcer activity, World J Gastroenterol 15: 1958-1965.
3. W.A. Hoogerwerf, P. J Pasricha (2001). Agents used for the control of gastric acidity and treatment of peptic ulcers and gastroesopahgeal reflux diseases. In: J.G Hardman., L.E Limbrid, C.S. Goodman, B.T Gilman. (eds.) Goodman and Gilman's: The pharmacological basis of therapeutics. 10th ed. New York: McGraw-Hill, pp. 1005-1019.
4. Z. P. Lima, J. A. Severi, C. H. Pellizzon, A. R. M. S. Brito, P. N. Solis, A. Caceres, L. M. Giron, W. Vilegas, C. A. Hiruma-Lima (2006). Can the aqueous decoction of mango flowers be used as antiulcer agent?, J Ethnopharmacol 106: 29-37.
5. C. Sostres, C. J. Gargallo, M. T. Arroyo, A. Lanas (2010). Adverse effects of nonsteroidal anti-inflammatory drugs(NSAIDs, as pirin and coxibs) on upper gastrointestinal tract. Best Practice and Research, Clinical Gastroenterology 24:121-32.
6. D. L Valle, (2005). Peptic ulcer diseases and related disorders. In: E. Braunwald, A. S. Fauci, D. L Kasper, S. L Hauser, D.L Longo, J. L. Jameson. (Eds.) Harrison's Principles of Internal Medicine 16: McGraw-Hill, New York, pp. 1746-1762.
7. A. E. Bighetti, M. A Antônio, L. K. Kohn, V. L. G. Rehder, M. A. Foglio, A. Possenti, L. Vilela, J. E. Carvalho (2005). Antiulcerogenic activity of a crude hydroalcoholic extract and coumarin isolated from Mikania laevigata Schultz Bip, Phytomedicine 12: 72-77.
8. V. Lakshimi, N. Singh, S. Shrivastva, S. K. Mishra, P. Dharmani, V. Mishra, G. Palit (2010). Gedunian and photogedunin of Xilocarpus granatum show significant antisecretory effects and protect the gastric mucosa of peptic ulcer in rats, Phytomedicine 17: 569-574.
9. K. S. Jain, A. K. Shah, J. Bariwal, S. M. Shelke, A. P. Kale, J. R. Jagtapc, A.V. Bhosale (2007). Recent advances in proton pump inhibitors and management of acid-peptic disorders, Bioorg Med Chem. 15: 1181-1205.
10. A. Martelli, F. Mattlioli, E. Mereto, C. G. Brambilla, D. Sini, R. Bergamaschi, et al. (1998). Evaluation of omeprazole genotoxicity in a battery of in vitro and in vivo assays, Toxicology 30: 19-41.
11. M. M. Wolfef, G. Sachs. (2000). Acid suppression: optimizing therapy for gastroduodenal ulcer healing, gastrooesophageal disease and stress-related erosive syndrome, Gastroenterology 118: S9-S31.
12. K. Sairam, C. V. Rao, R. K. Goel. (2001). Effect of Centella asiatica Linn. on physical and chemical factors induced gastric ulceration and secretion, Indian J Exp Biol. 39: 137.
13. R. K. Goel, K. Sairam. (2002). Antiulcer drugs from indigenous sources with emphasis on Musa sapientum, Tamrabhasna, Asparagus racemosus and Zingiber officinale, Ind J Pharmacol 34: 100-110.
14. M. Indran, A. Mahmood, U. Kuppusamy. (2008). Protective effect of Carica papaya L leaf extract against alcohol induced acute gastric damage and blood oxidative stress in rats, West Indian Med. J. 57: 323-326.
15. A. Mahmood, A.A. (2010). Mariod, F.A.I-Bayaty, S.I. Abdel-Wahab. Anti-ulcerogenic activity of Gynura procumbens leaf extract against experimental-induced gastric lesions in rats, J. Med. Plant Res. 4: 685-691.
16. H. S. Falcão, I. R. Mariath, M. F. F. M. Diniz, L. M. Batista, J. M. Barbosa filho. (2008). Plants of the American continent with antiulcer activity, Phytomedicine (Stuttgart) 15: 132-146.
17. A. M. Giulietti, J. R. Pirani. (1988). Patterns of geographic distribution of some plant species from the Espinhaço Range, Minas Gerais and Bahia, Brazil. In: W.R. Heyer, P.E. Vanzolini, eds. Proceedings of a Workshop on Neotropical Distribution Patterns. Rio de Janeiro: Academia Brasileira de Ciências, pp. 39-69.
18. A. M. Giulietti, N. Hensold. (1990). Padrões de distribuição geográfica dos gêneros de Eriocaulaceae, Acta Botanica Brasilica 4: 133-158.
19. L.R.P Lazzari. (2000). Redelimitacão e revisão de Syngonanthus Sect. Eulepis (Bong. ex Koern.) Ruhland - Eriocaulaceae. PhD Thesis, Universidade de São Paulo, Brazil.
20. E. C. Bate-Smith, J. B. J.B. Harborne. (1969). Quercetagetin and patuletin in Eriocaulon, Phytochemistry 8: 1035-1037.
21. W. Vilegas, C. J. Nehme, A. L. Dokkeddal, S. Piacente, L. Rastrelli, C. Pizza. (1999). Quercetagetin 7-methyl ether glycosides from Paepalanthus vellozioides and Paepalanthus latipes, Phytochemistry 51: 403-409.
22. K. S. L Mota, G. E. N. Dias, M. E. F. Pinto, Â. Luiz-Ferreira, A. R. Monteiro Souza-Brito, C. A. Hiruma Lima, J. M. Barbosa Filho, L. M. Batista. (2009). Flavonoids with Gastroprotective Activity, Molecules 14: 979-1012.
23. R. G. Coelho, L. M. Batista, L. C. Santos, A. R. M. S Brito, W. Vilegas. (2006) Phytochemical study and antiulcerogenic activity of Syngonanthus bisulcatus (Eriocaulaceae), Braz J Pharm Sci 42: 413-417.
24. Y. Morimoto, K. Shimohara, S. Oshima, T. Sukayuki. (1991). Effects of the new anti-ulcer agent KB-5492 on experimental gastric mucosal lesion and gastric mucosal defensive factors, as compared to those of teprenone and cimetidine, Japan J Pharmacol 57: 495-505.
25. I. Szelenyi, K. Thiemer. (1978). Distention ulcer as a model for testing of drugs for ulcerogenic side effects, Arch Toxicol 41: 99-105.
26. S.E. Senay, R. J. Levine. (1967). Synergism between cold and restraint for rapid production of stress ulcer in rats, Proc. Soc. Exp. Biol. Med 124:1221-1223.
27. K.D Rainsford. (1978). Gastric Ulcerogenicity of non-steroidal anti-inflamatory drugas in mice with mucosa sensitized by cholinomimetic treatment, Biochem. Pharmacol 27: 1281-1289.
28. H. Shay, S. A. Komarov, S. S. Fels, D. Meranze, M. Gruenstein, H. Siplet. (1945). A simple method for the uniform production of gastric ulceration in the rat, Gastroenterol 5: 43-61.
29. S. Raffatullah, M. Tariq, M. A. Al-Yahya, J. S. Mossa, A. M. Ageel. (1990). Evaluation of turmeric (Curcuma longa) for gastric and duodenal antiulcer activity in rats, J Ethnopharmacol 29: 25-34.
30. G. H. Curtis, W. K. Macnaughton, D. G. Gall, J. L. Wallace. (1995). Intraluminal pH modulates gastric prostaglandin synthesis, Can J Physiol Pharmacol 73: 130 134.
31. N. Jahovic, G. Erkanli, S. Iseri, S. Arbak, I. Alican. (2007). Gastric protection by [alpha]-melanocyte-stimulating hormone against ethanol in rats: involvement of somatostatin, Life Sciences 80: 1040-1045.
32. M.A. Abdulla, H. M. Ali, K. A. A. Ahmed, S. M. Noor, S. Ismail. (2009). Evaluation of the anti-ulcer activities of Morus alba extracts in experimentally-induced gastric ulcer in rats, Biomedical Research 20: 35-39.
33. P. Maity, K. Biswas, I. Chattopadhyay, R. K. Banerjee, U. Bandyopadhyay. (2009). The use of neem for controlling gastric hyperacidity and ulcer, Phytother Res 23: 747-755.
34. M. Goswami, M. Kulshreshtha, C.V. Rao, S. Yadav. (2011). Anti-ulcer potential of Lawsonia inermis L. leaves against gastric ulcers in rats, Journal of Applied Pharmaceutical Science 1: 69-72.
35. M. S. Salga, H. M. Ali, M. A. Abdullah, S. I. Abdelwahab, P. D. Hussain, A. H. A. Hadi. (2011). Mechanistic studies of the anti-ulcerogenic activity and acute toxicity evaluation of dichlorido-copper (II)-4-(2-5-bromo-benzylideneamino) ethyl) piperazin-1-ium phenolate complex against ethanol-induced gastric injury in rats, Molecules 16: 8654-8669.
36. L. Laine, K. Takeuchi, A. Tarnawski. (2008). Gastric mucosal defense and cytoprotection: bench to bedside, Gastroenterology 135: 41-60.
37. H. Kitagawa, M. Fujiwara, Y. Osumi. (1979). Effect of water-immersion stress on gastric secretion and mucosal blood flow in rats, Gastroenterology 77: 298-302.
38. D. Das, D. Bandyopadhyay, M. Bhattacharjee., R. K. Banerjee. (1997). Hydroxyl radical is the major causative factor in stress-induced gastric ulceration, Free Radical Biol. Med. 23: 8-18.
39. C. V. Rao, K. Sairam, R. K. Goel. (2000). Experimental evaluation of Bacopa monniera on rat gastric ulceration and secretion, Ind. J. Physiol. Pharmacol. 44: 35-41.
40. W. M. Shian, I. Sasaki, Y. Kamiyama, H. Naito, S. Matsuno, T. Miyazawa. (2000). The role of lipid peroxidation on gastric mucosal lesions induced by water immersion-restraint stress in rats, Surg. Today 30: 49-53.
41. K. Yasukawa, K. Kasazaki, F. Hyodo, H. Utsumi. (2004). Non-invasive analysis of reactive oxygen species generated in rats with water immersion restraint induced gastric lesions using in vivo electron spin resonance spectroscopy, Free Radical Res 38: 147-155.
42. T. Hase, B. J. Moss. (1973). Microvascular changes of gastric mucosa in development of stress ulcers in rats, Gastroenterology 65: 224-226.
43. G. Sigthorsson, R. Crane, T. Simon, M. Hoover, H. Quan, J. Bolognese, et al. (2000). COX-2 inhibition with rofecoxib does not increase intestinal permeability in healthy subjects: a double blind crossover study comparing rofecoxib with placebo and indomethacin, Gut 47: 527-532.
44. R. M Botting. (2006). Inhibitors of cyclooxygenases: mechanisms, selectivity and uses, J Physiol Pharmacol. 57: 113-124.
45. P. Patrignani. (2000). Nonsteroidal anti-inflammatory drugs, COX-2 and colorectal cancer, Toxicology Letters 112-113: 493-498.
46. S. K. Chiou, A. Hodges, N. Hoa. (2010). Suppression of growth arrest and DNA damage-inducible an expression confers resistance to sulindac and indomethacin-induced gastric mucosal injury, J Pharmacol Exp Ther 334:693-702.
47. S. Ishihara, M. A. Rumi, Y. Kadowaki, et al. (2004). Essential role of MD-2 in TLR4-dependent signaling during Helicobacter pylori-associated gastritis, J Immunol 173:1406-1416.
48. D. F. Magee, S. Naruse, Pap A. (1985). Comparison of the action of cholinomimetics and pentagastrin on gastric secretion in dogs, Br J Pharmacol 84: 347-355.
49. B. M. Peskar, N. Maricic. (1998). Role of prostaglandins in gastroprotection, Digestion Disease Sciences 43, 23S-29S.
50. C. A. Hiruma-Lima, T. R. Calvo, C. M. Rodrigues, F. D. Andrade, W. Vilegas, A. R. Brito.(2006). Antiulcerogenic activity of Alchornea castaneafolia: effects on somatostatin, gastrin and prostaglandin, J. ethnopharmacol 104: 215-224, 2006.
51. E. C. V. Rosenvinge, J. P Raufman. (2010). Gastrointestinal peptides and regulation of gastric acid secretion, Curr Opin Endocrinol Diabetes Obes., 17: 40-43.
52. F. Zanatta, R. B. Gandolfi, M. Lemos, J. C. Ticona, A. Gimenez, B. K. Clasen, et al. (2009) Gastroprotective activity of alkaloid extract and 2-phenylquinoline obtained from the bark of Galipea longiflora Krause (Rutaceae), Chem Biol Interact. 180: 312-317.
53. A. Allen, G. Flemströn. (2005). Gastroduodenal mucus bicarbonate barrier: protection against acid and pepsin, Am J Physiol Cell Physiol 288: 1-19.
54. J. L. Wallace. (2001). Mechanisms of protection and healing: current knowledge and future research, Am. J. Med. 110: 19S-22S.
55. J. L. Wallace. (2008). Prostaglandins, NSAIDs, and Gastric Mucosal Protection: Why Doesn't the Stomach Digest Itself deg;, Physiological Reviews 88: 1547-1565.
56. Y. Waisman, I. Zahavi, H. Marcus, M. Ligumsky, Y. Rosenbach, and G. Dinari. (1988). Sucralfate is protective against indomethacin-induced intestinal ulceration in the rat, Digestion 41: 78-82.
57. H. Ruppin, B. Person, A. Robert, and W. Domschke. (1981). Gastric cytoprotection in man by prostaglandin E2, Scand J Gastroenterol. 16: 647- 652.
58. - secretion in stomach, J Physiol Pharmacol. 57: 661-676, 2006.
59. T. Brzozowski, P. C. Konturek, S. J. Konturek, I. Brzozowska, T. Pawlik. (2005). Role of prostaglandins in gastroprotection and gastric adaptation, J. Physiol. Pharmacol. 56: 33-55.
60. B. Adhikary, S. K. Yadav, S. K. Bandyopadhyay, S. Chattopadhyay. (2011). Epigallocatechin gallate accelerates healing of indomethacin-induced stomach ulcers in mice, Pharmacol Rep. 63: 527-536.