Suppression of growth arrest and DNA damage-inducible 45α expression confers resistance to sulindac and indomethacin-induced gastric mucosal injury

Journal of Pharmacology and Experimental Therapeutics

Volumn 334, Issue 3, 2010, Pages 693-702

  Chiou, Shiun Kwei ^a   Hodges, Amy ^a   Hoa, Neil ^a  

^a VA LONG BEACH HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 9; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45ALPHA; INDOMETACIN; MESSENGER RNA; PROSTAGLANDIN E2; SMALL INTERFERING RNA; SULINDAC; UNCLASSIFIED DRUG; CASPASE INHIBITOR; CELL CYCLE PROTEIN; CYCLOOXYGENASE 2 INHIBITOR; GADD45A PROTEIN, RAT; NONSTEROID ANTIINFLAMMATORY AGENT; NUCLEAR PROTEIN; NUCLEIC ACID PROBE; PROSTAGLANDIN SYNTHASE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVATION; ENZYME ACTIVITY; EPITHELIUM CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STOMACH EPITHELIUM; STOMACH MUCOSA; STOMACH MUCOSA INJURY; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; C57BL MOUSE; CELL PROLIFERATION; CHEMICALLY INDUCED; DRUG EFFECTS; ENDOTHELIUM CELL; ENZYMOLOGY; KNOCKOUT MOUSE; METABOLISM; NUCLEIC ACID PROBE; PATHOLOGY; PHARMACOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH ULCER; TOXICITY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTISENSE ELEMENTS (GENETICS); APOPTOSIS; CASPASE 9; CASPASE INHIBITORS; CELL CYCLE PROTEINS; CELL PROLIFERATION; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; DNA DAMAGE; ENDOTHELIAL CELLS; ENZYME ACTIVATION; GASTRIC MUCOSA; HUMANS; INDOMETHACIN; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NUCLEAR PROTEINS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; STOMACH ULCER; SULINDAC; UP-REGULATION;

EID: 77956244664     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.168153     Document Type: Article

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