-
1
-
-
0029057336
-
A single ataxia telangiectasia gene with a product similar to PI-3 kinase
-
Savitsky K, Bar-Shira A, Gilad S, Rotman G, Ziv Y, Vanagaite L, et al. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 1995;268:1749-53.
-
(1995)
Science
, vol.268
, pp. 1749-1753
-
-
Savitsky, K.1
Bar-Shira, A.2
Gilad, S.3
Rotman, G.4
Ziv, Y.5
Vanagaite, L.6
-
2
-
-
0033544724
-
-
Stewart GS, Maser RS, Stankovic T, Bressan DA, Kaplan MI, Jaspers NG, et al. Cell 1999;99:577-87.
-
(1999)
Cell
, vol.99
, pp. 577-587
-
-
Stewart, G.S.1
Maser, R.S.2
Stankovic, T.3
Bressan, D.A.4
Kaplan, M.I.5
Jaspers, N.G.6
-
3
-
-
84555196106
-
BRCA1 and BRCA2: Different roles in a common pathway of genome protection
-
Roy R, Chun J, Powell SN. BRCA1 and BRCA2: different roles in a common pathway of genome protection. Nat Rev Cancer 2012;12: 68-78.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 68-78
-
-
Roy, R.1
Chun, J.2
Powell, S.N.3
-
4
-
-
0036900120
-
Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair
-
DOI 10.1128/MMBR.66.4.630-670.2002
-
Symington LS. Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol Mol Biol Rev 2002;66:630-70. (Pubitemid 35425112)
-
(2002)
Microbiology and Molecular Biology Reviews
, vol.66
, Issue.4
, pp. 630-670
-
-
Symington, L.S.1
-
5
-
-
33745474120
-
Break-induced replication and recombinational telomere elongation in yeast
-
DOI 10.1146/annurev.biochem.74.082803.133234
-
McEachern MJ, Haber JE. Break-induced replication and recombinational telomere elongation in yeast. Annu Rev Biochem 2006;75:111-35. (Pubitemid 44118028)
-
(2006)
Annual Review of Biochemistry
, vol.75
, pp. 111-135
-
-
McEachern, M.J.1
Haber, J.E.2
-
6
-
-
50649100744
-
Mechanism of eukaryotic homologous recombination
-
San Filippo J, Sung P, Klein H. Mechanism of eukaryotic homologous recombination. Annu Rev Biochem 2008;77:229-57.
-
(2008)
Annu Rev Biochem
, vol.77
, pp. 229-257
-
-
San Filippo, J.1
Sung, P.2
Klein, H.3
-
7
-
-
77649131406
-
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
-
Moynahan ME, Jasin M. Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis. Nat Rev Mol Cell Biol 2010;11:196-207.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 196-207
-
-
Moynahan, M.E.1
Jasin, M.2
-
8
-
-
0016274036
-
A genetic study of X-ray sensitive mutants in yeast
-
Game JC, Mortimer RK. A genetic study of X-ray sensitive mutants in yeast. Mutat Res 1974;24:281-92.
-
(1974)
Mutat Res
, vol.24
, pp. 281-292
-
-
Game, J.C.1
Mortimer, R.K.2
-
9
-
-
0035844122
-
Human RAD52 exhibits two modes of self-association
-
Ranatunga W, Jackson D, Lloyd JA, Forget AL, Knight KL, Borgstahl GE. Human RAD52 exhibits two modes of self-association. J Biol Chem 2001;276:15876-80.
-
(2001)
J Biol Chem
, vol.276
, pp. 15876-15880
-
-
Ranatunga, W.1
Jackson, D.2
Lloyd, J.A.3
Forget, A.L.4
Knight, K.L.5
Borgstahl, G.E.6
-
10
-
-
0029744334
-
DNA strand annealing is promoted by the yeast RaD52 protein
-
DOI 10.1073/pnas.93.20.10729
-
Mortensen UH, Bendixen C, Sunjevaric I, Rothstein R. DNA strand annealing is promoted by the yeast Rad52 protein. Proc Natl Acad Sci U S A 1996;93:10729-34. (Pubitemid 26333057)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.20
, pp. 10729-10734
-
-
Mortensen, U.H.1
Bendixen, C.2
Sunjevaric, I.3
Rothstein, R.4
-
11
-
-
0027227980
-
Dominant negative alleles of RAD52 reveal a DNA repair/recombination complex including Rad51 and Rad52
-
Milne GT, Weaver DT. Dominant negative alleles of RAD52 reveal a DNA repair/recombination complex including Rad51 and Rad52. Genes Dev 1993;7:1755-65. (Pubitemid 23269321)
-
(1993)
Genes and Development
, vol.7
, Issue.9
, pp. 1755-1765
-
-
Milne, G.T.1
Weaver, D.T.2
-
12
-
-
0032556898
-
Stimulation by Rad52 of yeast Rad51-mediated recombination
-
DOI 10.1038/34943
-
Shinohara A, Ogawa T. Stimulation by Rad52 of yeast Rad51-mediated recombination. Nature 1998;391:404-7. (Pubitemid 28093517)
-
(1998)
Nature
, vol.391
, Issue.6665
, pp. 404-407
-
-
Shinohara, A.1
Ogawa, T.2
-
13
-
-
0032556870
-
Rad52 protein stimulates DNA strand exchange by Rad51 and replication protein A
-
DOI 10.1038/34950
-
New J, Sugiyama T, Zaitseva E. Rad52 protein stimulates DNA strand exchange by Rad51 and replication proteinA. Nature 1998;391:407-10. (Pubitemid 28093518)
-
(1998)
Nature
, vol.391
, Issue.6665
, pp. 407-410
-
-
New, J.H.1
Sugiyama, T.2
Zaitseva, E.3
Kowalczykowski, S.C.4
-
14
-
-
0030666945
-
Function of yeast Rad52 protein as a mediator between replication protein A and the Rad51 recombinase
-
DOI 10.1074/jbc.272.45.28194
-
Sung P. Function of yeast Rad52 protein as a mediator between replication protein A and the Rad51 recombinase. J Biol Chem 1997;272:28194-7. (Pubitemid 27517755)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.45
, pp. 28194-28197
-
-
Sung, P.1
-
15
-
-
0031835781
-
Studies of the interaction between Rad52 protein and the yeast single- stranded DNA binding protein RPA
-
Hays SL, Firmenich AA, Massey P, Berg P. Studies of the Interaction between Rad52 protein and the yeast single-stranded DNA binding protein RPA. Mol Cell Biol 1998;18:4400-6. (Pubitemid 28287963)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.7
, pp. 4400-4406
-
-
Hays, S.L.1
Firmenich, A.A.2
Massey, P.3
Banerjee, R.4
Berg, P.5
-
16
-
-
0031902872
-
Rad52 forms ring structures and co-operates with RPA in single-strand DNA annealing
-
DOI 10.1046/j.1365-2443.1998.00176.x
-
Shinohara A, Shinohara M, Ohta T, Matsuda S, Ogawa T. Rad52 forms ring structures and co-operates with RPA in single-strand DNA annealing. Genes Cells 1998;3:145-56. (Pubitemid 28374987)
-
(1998)
Genes to Cells
, vol.3
, Issue.3
, pp. 145-156
-
-
Shinohara, A.1
Shinohara, M.2
Ohta, T.3
Matsuda, S.4
Ogawa, T.5
-
17
-
-
0036349930
-
Analysis of the human replication protein A:Rad52 complex: Evidence for crosstalk between RPA32, RPA70, Rad52 and DNA
-
DOI 10.1016/S0022-2836(02)00541-7
-
Jackson D. Analysis of the human replication protein A:Rad52 complex: evidence for crosstalk between RPA32, RPA70, Rad52 and DNA. J Mol Biol 2002;321:133-48. (Pubitemid 34948475)
-
(2002)
Journal of Molecular Biology
, vol.321
, Issue.1
, pp. 133-148
-
-
Jackson, D.1
Dhar, K.2
Wahl, J.K.3
Wold, M.S.4
Borgstahl, G.E.O.5
-
19
-
-
33751560821
-
Rad52-mediated DNA annealing after Rad51-mediated DNA strand exchange promotes second ssDNA capture
-
DOI 10.1038/sj.emboj.7601412, PII 7601412
-
Sugiyama T, Kantake N, Wu Y, Kowalczykowski SC. Rad52-mediated DNA annealing after Rad51-mediated DNA strand exchange promotes second ssDNA capture. EMBO J 2006;25:5539-48. (Pubitemid 44847194)
-
(2006)
EMBO Journal
, vol.25
, Issue.23
, pp. 5539-5548
-
-
Sugiyama, T.1
Kantake, N.2
Wu, Y.3
Kowalczykowski, S.C.4
-
20
-
-
0032808218
-
Heteroduplex formation by human Rad51 protein: Effects of DNA end-structure, hRP-A and hRad52
-
DOI 10.1006/jmbi.1999.2954
-
Baumann P, West SC. Heteroduplex formation by human Rad51 protein: effects of DNA end-structure, hRP-A and hRad52. J Mol Biol 1999;291:363-74. (Pubitemid 29381433)
-
(1999)
Journal of Molecular Biology
, vol.291
, Issue.2
, pp. 363-374
-
-
Baumann, P.1
West, S.C.2
-
21
-
-
0037108889
-
Structure of the single-strand annealing domain of human RAD52 protein
-
DOI 10.1073/pnas.212449899
-
Singleton MR, Wentzell LM, Liu Y, West SC, Wigley DB. Structure of the single-strand annealing domain of human RAD52 protein. Proc Natl Acad Sci U S A 2002;99:13492-7. (Pubitemid 35215409)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.21
, pp. 13492-13497
-
-
Singleton, M.R.1
Wentzell, L.M.2
Liu, Y.3
West, S.C.4
Wigley, D.B.5
-
22
-
-
0036671363
-
Crystal structure of the homologous-pairing domain from the human Rad52 recombinase in the undecameric form
-
DOI 10.1016/S1097-2765(02)00587-7
-
Kagawa W, Kurumizaka H, Ishitani R, Fukai S, Nureki O, Shibata T, et al. Crystal structure of the homologous-pairing domain from the human Rad52 recombinase in the undecameric form. Mol Cell 2002;10:359-71. (Pubitemid 35007350)
-
(2002)
Molecular Cell
, vol.10
, Issue.2
, pp. 359-371
-
-
Kagawa, W.1
Kurumizaka, H.2
Ishitani, R.3
Fukai, S.4
Nureki, O.5
Shibata, T.6
Yokoyama, S.7
-
23
-
-
9644276839
-
Identification of residues important for DNA binding in the full-length human Rad52 protein
-
DOI 10.1016/j.jmb.2004.10.065, PII S0022283604013713
-
Lloyd JA, McGrew DA, Knight KL. Identification of residues important for DNA binding in the full-length human Rad52 protein. J Mol Biol 2005;345:239-49. (Pubitemid 39574847)
-
(2005)
Journal of Molecular Biology
, vol.345
, Issue.2
, pp. 239-249
-
-
Lloyd, J.A.1
McGrew, D.A.2
Knight, K.L.3
-
24
-
-
0035989355
-
A molecular genetic dissection of the evolutionarily conserved N terminus of yeast Rad52
-
Mortensen UH, Erdeniz N, Feng Q, Rothstein R. A molecular genetic dissection of the evolutionarily conserved N terminus of yeast Rad52. Genetics 2002;161:549-62. (Pubitemid 34705397)
-
(2002)
Genetics
, vol.161
, Issue.2
, pp. 549-562
-
-
Mortensen, U.H.1
Erdeniz, N.2
Feng, Q.3
Rothstein, R.4
-
25
-
-
53049093612
-
Identification of a second DNA binding site in the human Rad52 protein
-
Kagawa W, Kagawa A, Saito K, Ikawa S, Shibata T, Kurumizaka H, et al. Identification of a second DNA binding site in the human Rad52 protein. J Biol Chem 2008;283:24264-73.
-
(2008)
J Biol Chem
, vol.283
, pp. 24264-24273
-
-
Kagawa, W.1
Kagawa, A.2
Saito, K.3
Ikawa, S.4
Shibata, T.5
Kurumizaka, H.6
-
26
-
-
79955958189
-
Vital roles of the second DNA-binding site of Rad52 protein in yeast homologous recombination
-
Arai N, Kagawa W, Saito K, Shingu Y, Mikawa T, Kurumizaka H, et al. Vital roles of the second DNA-binding site of Rad52 protein in yeast homologous recombination. J Biol Chem 2011;286:17607-17.
-
(2011)
J Biol Chem
, vol.286
, pp. 17607-17617
-
-
Arai, N.1
Kagawa, W.2
Saito, K.3
Shingu, Y.4
Mikawa, T.5
Kurumizaka, H.6
-
27
-
-
77957975815
-
Purified human BRCA2 stimulates RAD51-mediated recombination
-
Jensen RB, Carreira A, Kowalczykowski SC. Purified human BRCA2 stimulates RAD51-mediated recombination. Nature 2010;467:678-83.
-
(2010)
Nature
, vol.467
, pp. 678-683
-
-
Jensen, R.B.1
Carreira, A.2
Kowalczykowski, S.C.3
-
28
-
-
84880916205
-
RAD52 inactivation is synthetically lethal with deficiencies in BRCA1 and PALB2 in addition to BRCA2 through RAD51-mediated homologous recombination
-
Lok BH, Carley AC, Tchang B, Powell SN. RAD52 inactivation is synthetically lethal with deficiencies in BRCA1 and PALB2 in addition to BRCA2 through RAD51-mediated homologous recombination. Oncogene 2012:1-7.
-
(2012)
Oncogene
, pp. 1-7
-
-
Lok, B.H.1
Carley, A.C.2
Tchang, B.3
Powell, S.N.4
-
29
-
-
79551658805
-
Rad52 inactivation is synthetically lethal with BRCA2 deficiency
-
Feng Z, Scott SP, Bussen W, Sharma GG, Guo G, Pandita TK, et al. Rad52 inactivation is synthetically lethal with BRCA2 deficiency. Proc Natl Acad Sci U S A 2011;108:686-91.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 686-691
-
-
Feng, Z.1
Scott, S.P.2
Bussen, W.3
Sharma, G.G.4
Guo, G.5
Pandita, T.K.6
-
30
-
-
84871612831
-
The Rad51 paralog complexes BCDX2 and CX3 act at different stages in the BRCA1-BRCA2 dependent homologous recombination pathway
-
Epub 2012 Nov 12
-
Chun J, Buechelmaier ES, Powell SN. The Rad51 paralog complexes BCDX2 and CX3 act at different stages in the BRCA1-BRCA2 dependent homologous recombination pathway. Mol Cell Biol. Epub 2012 Nov 12.
-
Mol Cell Biol
-
-
Chun, J.1
Buechelmaier, E.S.2
Powell, S.N.3
-
31
-
-
82355181545
-
hSWS1·SWSAP1 is an evolutionarily conserved complex required for efficient homologous recombination repair
-
Liu T, Wan L, Wu Y, Chen J, Huang J. hSWS1·SWSAP1 is an evolutionarily conserved complex required for efficient homologous recombination repair. J Biol Chem 2011;286:41758-66.
-
(2011)
J Biol Chem
, vol.286
, pp. 41758-41766
-
-
Liu, T.1
Wan, L.2
Wu, Y.3
Chen, J.4
Huang, J.5
-
32
-
-
79955799175
-
Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11
-
Schlacher K, Christ N, Siaud N, Egashira A, Wu H, Jasin M. Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11. Cell 2011;145:529-42.
-
(2011)
Cell
, vol.145
, pp. 529-542
-
-
Schlacher, K.1
Christ, N.2
Siaud, N.3
Egashira, A.4
Wu, H.5
Jasin, M.6
-
33
-
-
0343621499
-
Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana
-
Mayer K, Schüller C, Wambutt R, Murphy G, Volckaert G, Pohl T, et al. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Nature 1999;402:769-77.
-
(1999)
Nature
, vol.402
, pp. 769-777
-
-
Mayer, K.1
Schüller, C.2
Wambutt, R.3
Murphy, G.4
Volckaert, G.5
Pohl, T.6
-
34
-
-
67649348221
-
Inefficient double-strand DNA break repair is associated with increased fasciation in Arabidopsis BRCA2 mutants
-
Abe K, Osakabe K, Ishikawa Y, Tagiri A, Yamanouchi H, Takyuu T, et al. Inefficient double-strand DNA break repair is associated with increased fasciation in Arabidopsis BRCA2 mutants. J Exp Botany 2009;60:2751-61.
-
(2009)
J Exp Botany
, vol.60
, pp. 2751-2761
-
-
Abe, K.1
Osakabe, K.2
Ishikawa, Y.3
Tagiri, A.4
Yamanouchi, H.5
Takyuu, T.6
-
35
-
-
36549037672
-
Functional analysis of Drosophila melanogaster BRCA2 in DNA repair
-
DOI 10.1016/j.dnarep.2007.07.013, PII S1568786407002625
-
Brough R, Wei D, Leulier S, Lord CJ, Rong YS, Ashworth A. Functional analysis of Drosophila melanogaster BRCA2 in DNA repair. DNA Rep 2008;7:10-9. (Pubitemid 350184401)
-
(2008)
DNA Repair
, vol.7
, Issue.1
, pp. 10-19
-
-
Brough, R.1
Wei, D.2
Leulier, S.3
Lord, C.J.4
Rong, Y.S.5
Ashworth, A.6
-
36
-
-
40149090856
-
Drosophila brca2 is required for mitotic and meiotic DNA repair and efficient activation of the meiotic recombination checkpoint
-
Klovstad M, Abdu U, Schüpbach T. Drosophila brca2 is required for mitotic and meiotic DNA repair and efficient activation of the meiotic recombination checkpoint. PLoS Genet 2008;4:e31.
-
(2008)
PLoS Genet
, vol.4
-
-
Klovstad, M.1
Abdu, U.2
Schüpbach, T.3
-
37
-
-
33746189731
-
CeBRC-2 Stimulates D-loop Formation by RAD-51 and Promotes DNA Single-strand Annealing
-
DOI 10.1016/j.jmb.2006.06.020, PII S0022283606007352
-
Petalcorin MIR, Sandall J, Wigley DB, Boulton SJ. CeBRC-2 stimulates D-loop formation by RAD-51 and promotes DNA single-strand annealing. J Mol Biol 2006;361:231-42. (Pubitemid 44092785)
-
(2006)
Journal of Molecular Biology
, vol.361
, Issue.2
, pp. 231-242
-
-
Petalcorin, M.I.R.1
Sandall, J.2
Wigley, D.B.3
Boulton, S.J.4
-
38
-
-
34249892132
-
Stabilization of RAD-51-DNA filaments via an interaction domain in Caenorhabditis elegans BRCA2
-
DOI 10.1073/pnas.0702805104
-
Petalcorin MIR, Galkin VE, Yu X, Egelman EH, Boulton SJ. Stabilization of RAD-51-DNA filaments via an interaction domain in Caenorhabditis elegans BRCA2. Proc Natl Acad Sci U S A 2007;104:8299-304. (Pubitemid 47175482)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.20
, pp. 8299-8304
-
-
Petalcorin, M.I.R.1
Galkin, V.E.2
Yu, X.3
Egelman, E.H.4
Boulton, S.J.5
-
39
-
-
0036752956
-
BRCA2 homolog required for proficiency in DNA repair, recombination, and genome stability in Ustilago maydis
-
DOI 10.1016/S1097-2765(02)00632-9
-
Kojic M, Kostrub CF, Buchman AR, Holloman WK. BRCA2 homolog required for proficiency in DNA repair, recombination, and genome stability in Ustilago maydis. Mol Cell 2002;10:683-91. (Pubitemid 35284183)
-
(2002)
Molecular Cell
, vol.10
, Issue.3
, pp. 683-691
-
-
Kojic, M.1
Kostrub, C.F.2
Buchman, A.R.3
Holloman, W.K.4
-
40
-
-
38849159142
-
Compensatory role for Rad52 during recombinational repair in Ustilago maydis
-
DOI 10.1111/j.1365-2958.2008.06116.x
-
Kojic M, Mao N, Zhou Q, Lisby M, Holloman WK. Compensatory role for Rad52 during recombinational repair in Ustilago maydis. Mol Microbiol 2008;67:1156-68. (Pubitemid 351207340)
-
(2008)
Molecular Microbiology
, vol.67
, Issue.5
, pp. 1156-1168
-
-
Kojic, M.1
Mao, N.2
Zhou, Q.3
Lisby, M.4
Holloman, W.K.5
-
41
-
-
0031741863
-
Targeted inactivation of mouse RAD52 reduces homologous recombination but not resistance to ionizing radiation
-
Rijkers T, Van Den Ouweland J, Morolli B, Rolink AG, Baarends WM, Van Sloun PP, et al. Targeted inactivation of mouse RAD52 reduces homologous recombination but not resistance to ionizing radiation. Mol Cell Biol 1998;18:6423-9. (Pubitemid 28500532)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.11
, pp. 6423-6429
-
-
Rijkers, T.1
Van Den, O.J.2
Morolli, B.3
Rolink, A.G.4
Baarends, W.M.5
Van Sloun, P.P.H.6
Lohman, P.H.M.7
Pastink, A.8
-
42
-
-
0031741550
-
Homologous recombination, but not DNA repair, is reduced in vertebrate cells deficient in RAD52
-
Yamaguchi-iwai Y, Sonoda E, Bezzubova O, Morrison C, Buerstedde J-marie. Homologous recombination, but not DNA repair, is reduced in vertebrate cells deficient in RAD52. Mol Cell Biol 1998;18:6430-5. (Pubitemid 28500533)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.11
, pp. 6430-6435
-
-
Yamaguchi-Iwai, Y.1
Sonoda, E.2
Buerstedde, J.-M.3
Bezzubova, O.4
Morrison, C.5
Takata, M.6
Shinohara, A.7
Takeda, S.8
-
43
-
-
17944373792
-
Rad52 partially substitutes for the Rad51 paralog XRCC3 in maintaining chromosomal integrity in vertebrate cells
-
DOI 10.1093/emboj/20.19.5513
-
Fujimori A, Tachiiri S, Sonoda E, Thompson LH, Dhar PK, Hiraoka M, et al. Rad52 partially substitutes for the Rad51 paralog XRCC3 in maintaining chromosomal integrity in vertebrate cells. EMBO J 2001;20:5513-20. (Pubitemid 32959471)
-
(2001)
EMBO Journal
, vol.20
, Issue.19
, pp. 5513-5520
-
-
Fujimori, A.1
Tachiiri, S.2
Sonoda, E.3
Thompson, L.H.4
Dhar, P.K.5
Hiraoka, M.6
Takeda, S.7
Zhang, Y.8
Reth, M.9
Takata, M.10
-
44
-
-
79960962204
-
The epistatic relationship between BRCA2 and the other RAD51 mediators in homologous recombination
-
Qing Y, Yamazoe M, Hirota K, Dejsuphong D, Sakai W, Yamamoto KN, et al. The epistatic relationship between BRCA2 and the other RAD51 mediators in homologous recombination. PLoS Genet 2011;7: e1002148.
-
(2011)
PLoS Genet
, vol.7
-
-
Qing, Y.1
Yamazoe, M.2
Hirota, K.3
Dejsuphong, D.4
Sakai, W.5
Yamamoto, K.N.6
-
45
-
-
67651166786
-
PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2
-
Zhang F, Fan Q, Ren K, Andreassen PR. PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2. Mol Cancer Res 2009;7:1110-8.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 1110-1118
-
-
Zhang, F.1
Fan, Q.2
Ren, K.3
Andreassen, P.R.4
-
46
-
-
66349096607
-
PALB2 is an integral component of the BRCA complex required for homologous recombination repair
-
Sy SMH, Huen MSY, Chen J. PALB2 is an integral component of the BRCA complex required for homologous recombination repair. Proc Natl Acad Sci U S A 2009;106:7155-60.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 7155-7160
-
-
Sy, S.M.H.1
Huen, M.S.Y.2
Chen, J.3
-
47
-
-
62549115236
-
PALB2 Links BRCA1 and BRCA2 in the DNA-damage response
-
Zhang F, Ma J, Wu J, Ye L, Cai H, Xia B, et al. PALB2 Links BRCA1 and BRCA2 in the DNA-damage response. Curr Biol 2009;19:524-9.
-
(2009)
Curr Biol
, vol.19
, pp. 524-529
-
-
Zhang, F.1
Ma, J.2
Wu, J.3
Ye, L.4
Cai, H.5
Xia, B.6
-
48
-
-
17244375049
-
Specific killing of BRCA2-deficient tumours with inhibitors of poly (ADP-ribose) polymerase
-
Bryant H, Schultz N, Thomas H, Parker K. Specific killing of BRCA2- deficient tumours with inhibitors of poly (ADP-ribose) polymerase. Nature 2005;7:913-8.
-
(2005)
Nature
, vol.7
, pp. 913-918
-
-
Bryant, H.1
Schultz, N.2
Thomas, H.3
Parker, K.4
-
49
-
-
84870330172
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
Farmer H, Mccabe N, Lord CJ. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 2005;239:236-9.
-
(2005)
Nature
, vol.239
, pp. 236-239
-
-
Farmer, H.1
Mccabe, N.2
Lord, C.J.3
-
50
-
-
80052168685
-
The underlying mechanism for the PARP and BRCA synthetic lethality: Clearing up the misunderstandings
-
Helleday T. The underlying mechanism for the PARP and BRCA synthetic lethality: clearing up the misunderstandings. Mol Oncol 2011;5:387-93.
-
(2011)
Mol Oncol
, vol.5
, pp. 387-393
-
-
Helleday, T.1
-
51
-
-
77950023283
-
PARP inhibition: PARP1 and beyond
-
Rouleau M, Patel A, Hendzel MJ, Kaufmann SH, Poirier GG. PARP inhibition: PARP1 and beyond. Nat Rev Cancer 2010;10:293-301.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 293-301
-
-
Rouleau, M.1
Patel, A.2
Hendzel, M.J.3
Kaufmann, S.H.4
Poirier, G.G.5
-
52
-
-
67650471685
-
Inhibition of poly (ADP-ribose) polymerase in tumors from BRCA mutation carriers
-
Fong PC, Boss DS, Yap TA, Tutt A, Wu P, Mergui-Roelvink M, et al. Inhibition of poly (ADP-ribose) polymerase in tumors from BRCA mutation carriers. N Engl J Med 2009;361:123-34.
-
(2009)
N Engl J Med
, vol.361
, pp. 123-134
-
-
Fong, P.C.1
Boss, D.S.2
Yap, T.A.3
Tutt, A.4
Wu, P.5
Mergui-Roelvink, M.6
-
53
-
-
77955039099
-
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: A proof-of-concept trial
-
Audeh MW, Carmichael J, Penson RT, Friedlander M, Powell B, Bell-McGuinn KM, et al. Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial. Lancet 2010;376:245-51.
-
(2010)
Lancet
, vol.376
, pp. 245-251
-
-
Audeh, M.W.1
Carmichael, J.2
Penson, R.T.3
Friedlander, M.4
Powell, B.5
Bell-McGuinn, K.M.6
-
54
-
-
77955019276
-
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: A proof-of-concept trial
-
Tutt A, Robson M, Garber JE, Domchek SM, Audeh MW, Weitzel JN, et al. Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial. Lancet 2010;376:235-44.
-
(2010)
Lancet
, vol.376
, pp. 235-244
-
-
Tutt, A.1
Robson, M.2
Garber, J.E.3
Domchek, S.M.4
Audeh, M.W.5
Weitzel, J.N.6
-
55
-
-
78751610848
-
Iniparib plus chemotherapy in metastatic triple-negative breast cancer
-
O'Shaughnessy J, Osborne C, Pippen JE, Yoffe M, Patt D, Rocha C, et al. Iniparib plus chemotherapy in metastatic triple-negative breast cancer. N Engl J Med 2011;364:205-14.
-
(2011)
N Engl J Med
, vol.364
, pp. 205-214
-
-
O'Shaughnessy, J.1
Osborne, C.2
Pippen, J.E.3
Yoffe, M.4
Patt, D.5
Rocha, C.6
-
56
-
-
39849097680
-
Resistance to therapy caused by intragenic deletion in BRCA2
-
DOI 10.1038/nature06548, PII NATURE06548
-
Edwards SL, Brough R, Lord CJ, Natrajan R, Vatcheva R, Levine DA, et al. Resistance to therapy caused by intragenic deletion in BRCA2. Nature 2008;451:1111-5. (Pubitemid 351317441)
-
(2008)
Nature
, vol.451
, Issue.7182
, pp. 1111-1115
-
-
Edwards, S.L.1
Brough, R.2
Lord, C.J.3
Natrajan, R.4
Vatcheva, R.5
Levine, D.A.6
Boyd, J.7
Reis-Filho, J.S.8
Ashworth, A.9
-
57
-
-
0037073708
-
Regulation of ionizing radiation-induced Rad52 nuclear foci formation by c-Abl-mediated phosphorylation
-
DOI 10.1074/jbc.M208151200
-
Kitao H, Yuan Z-M. Regulation of ionizing radiation-induced Rad52 nuclear foci formation by c-Abl-mediated phosphorylation. J Biol Chem 2002;277:48944-8. (Pubitemid 35470865)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.50
, pp. 48944-48948
-
-
Kitao, H.1
Yuan, Z.-M.2
-
58
-
-
80155198806
-
Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding
-
Honda M, Okuno Y, Yoo J, Ha T, Spies M. Tyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding. EMBO J 2011;30:3368-82.
-
(2011)
EMBO J
, vol.30
, pp. 3368-3382
-
-
Honda, M.1
Okuno, Y.2
Yoo, J.3
Ha, T.4
Spies, M.5
-
60
-
-
77953696034
-
The putative nuclear localization signal of the human RAD52 protein is a potential sumoylation site
-
Saito K, Kagawa W, Suzuki T, Suzuki H, Yokoyama S, Saitoh H, et al. The putative nuclear localization signal of the human RAD52 protein is a potential sumoylation site. J Biochem 2010;147:833-42.
-
(2010)
J Biochem
, vol.147
, pp. 833-842
-
-
Saito, K.1
Kagawa, W.2
Suzuki, T.3
Suzuki, H.4
Yokoyama, S.5
Saitoh, H.6
-
61
-
-
34547591933
-
The Smc5-Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus
-
DOI 10.1038/ncb1619, PII NCB1619
-
Torres-Rosell J, Sunjevaric I, De Piccoli G, Sacher M, Eckert-Boulet N, Reid R, et al. The Smc5-Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus. Nat Cell Biol 2007;9:923-31. (Pubitemid 47190447)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.8
, pp. 923-931
-
-
Torres-Rosell, J.1
Sunjevaric, I.2
De Piccoli, G.3
Sacher, M.4
Eckert-Boulet, N.5
Reid, R.6
Jentsch, S.7
Rothstein, R.8
Aragon, L.9
Lisby, M.10
-
62
-
-
43849092514
-
Rad52 sumoylation and its involvement in the efficient induction of homologous recombination
-
Ohuchi T, Seki M, Branzei D, Maeda D, Ui A, Ogiwara H, et al. Rad52 sumoylation and its involvement in the efficient induction of homologous recombination. DNA Rep 2008;7:879-89.
-
(2008)
DNA Rep
, vol.7
, pp. 879-889
-
-
Ohuchi, T.1
Seki, M.2
Branzei, D.3
Maeda, D.4
Ui, A.5
Ogiwara, H.6
-
63
-
-
33750499289
-
Control of Rad52 recombination activity by double-strand break-induced SUMO modification
-
DOI 10.1038/ncb1488, PII NCB1488
-
Sacher M, Pfander B, Hoege C, Jentsch S. Control of Rad52 recombination activity by double-strand break-induced SUMO modification. Nat Cell Biol 2006;8:1284-90. (Pubitemid 44660594)
-
(2006)
Nature Cell Biology
, vol.8
, Issue.11
, pp. 1284-1290
-
-
Sacher, M.1
Pfander, B.2
Hoege, C.3
Jentsch, S.4
-
64
-
-
77955813573
-
Rad52 SUMOylation affects the efficiency of the DNA repair
-
Altmannova V, Eckert-Boulet N, Arneric M, Kolesar P, Chaloupkova R, Damborsky J, et al. Rad52 SUMOylation affects the efficiency of the DNA repair. Nucleic Acids Res 2010;38:4708-21.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 4708-4721
-
-
Altmannova, V.1
Eckert-Boulet, N.2
Arneric, M.3
Kolesar, P.4
Chaloupkova, R.5
Damborsky, J.6
-
65
-
-
79955738892
-
PARP- 1 expression in breast cancer including BRCA1-associated, triple negative and basal-like tumors: Possible implications for PARP-1 inhibitor therapy
-
Domagala P, Huzarski T, Lubinski J, Gugala K, Domagala W. PARP- 1 expression in breast cancer including BRCA1-associated, triple negative and basal-like tumors: possible implications for PARP-1 inhibitor therapy. Breast Cancer Res Treat 2011;127:861-9.
-
(2011)
Breast Cancer Res Treat
, vol.127
, pp. 861-869
-
-
Domagala, P.1
Huzarski, T.2
Lubinski, J.3
Gugala, K.4
Domagala, W.5
-
66
-
-
69449090092
-
Utility of DNA repair protein foci for the detection of putative BRCA1 pathway defects in breast cancer biopsies
-
Willers H, Taghian AG, Luo C-M, Treszezamsky A, Sgroi DC, Powell SN. Utility of DNA repair protein foci for the detection of putative BRCA1 pathway defects in breast cancer biopsies. Mol Cancer Res 2009;7:1304-9.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 1304-1309
-
-
Willers, H.1
Taghian, A.G.2
Luo, C.-M.3
Treszezamsky, A.4
Sgroi, D.C.5
Powell, S.N.6
-
67
-
-
77950974130
-
Development of a functional assay for homologous recombination status in primary cultures of epithelial ovarian tumor and correlation with sensitivity to poly(ADP-ribose) polymerase inhibitors
-
Mukhopadhyay A, Elattar A, Cerbinskaite A, Wilkinson SJ, Drew Y, Kyle S, et al. Development of a functional assay for homologous recombination status in primary cultures of epithelial ovarian tumor and correlation with sensitivity to poly(ADP-ribose) polymerase inhibitors. Clin Cancer Res 2010;16:2344-51.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2344-2351
-
-
Mukhopadhyay, A.1
Elattar, A.2
Cerbinskaite, A.3
Wilkinson, S.J.4
Drew, Y.5
Kyle, S.6
-
68
-
-
33749037701
-
Mechanism of homologous recombination: Mediators and helicases take on regulatory functions
-
DOI 10.1038/nrm2008, PII NRM2008
-
Sung P, Klein H. Mechanism of homologous recombination: mediators and helicases take on regulatory functions. Nat Rev Mol Cell Biol 2006;7:739-50. (Pubitemid 44450458)
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, Issue.10
, pp. 739-750
-
-
Sung, P.1
Klein, H.2
|