Preparation and in vivo pharmacokinetics of curcumin-loaded PCL-PEG-PCL triblock copolymeric nanoparticles

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 4089-4098

  Feng, Runliang ^a   Song, Zhimei ^a   Zhai, Guangxi ^b  

^a UNIVERSITY OF JINAN   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Copolymer; Hydrophilic chain; Hydrophobic chain; Nanoparticle; Solubility

Indexed keywords

COPOLYMER; CURCUMIN; MACROGOL; NANOPARTICLE; POLY(EPSILON CAPROLACTONE)POLY(ETHYLENE GLYCOL)POLY(EPSILON CAPROLACTONE) COPOLYMER; POLYCAPROLACTONE; UNCLASSIFIED DRUG;

ANALYTICAL PARAMETERS; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CHEMICAL BOND; CHEMICAL STRUCTURE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG DISTRIBUTION; DRUG DOSAGE FORM COMPARISON; DRUG HALF LIFE; DRUG LOADING; DRUG SOLUBILITY; DRUG SYNTHESIS; ENTRAPMENT EFFICIENCY; GEL PERMEATION CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; LIGHT SCATTERING; MEAN RESIDENCE TIME; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PROBE TYPE ULTRASONIC EMULSION METHOD; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SLOW DRUG RELEASE; SOLVENT EVAPORATION METHOD; STEADY STATE VOLUME DISTRIBUTION; SUSTAINED DRUG RELEASE; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

ANIMALS; CHROMATOGRAPHY, GEL; CURCUMIN; DRUG CARRIERS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; NANOPARTICLES; PARTICLE SIZE; POLYESTERS; POLYETHYLENE GLYCOLS; RATS; RATS, WISTAR; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TEMPERATURE;

EID: 84870372021     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S33607     Document Type: Article

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