Essential role of an unknown gene aziU3 in the production of antitumor antibiotic azinomycin B verified by utilizing optimized genetic manipulation systems for Streptomyces sahachiroi

FEMS Microbiology Letters

Volumn 337, Issue 2, 2012, Pages 147-154

  Wang, Shan ^a   Zhao, Ruifang ^a   Liu, Kai ^a   Zhu, Mengyi ^a   Li, Aiying ^b   He, Jing ^a  

^a HUAZHONG AGRICULTURAL UNIVERSITY   (China)

^b CENTRAL CHINA NORMAL UNIVERSITY   (China)

Author keywords

Azinomycin B; Functional analysis; Intergeneric conjugation; Protoplast transformation; Streptomyces sahachiroi

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; AZINOMYCIN B; UNCLASSIFIED DRUG;

ARTICLE; AZIU3 GENE; CONTROLLED STUDY; DNA TRANSFER; DRUG STRUCTURE; DRUG SYNTHESIS; FUNGAL GENE; FUNGAL STRAIN; GENE DELETION; GENE DOSAGE; GENE FUNCTION; GENE OVEREXPRESSION; GENETIC COMPLEMENTATION; GENETIC MANIPULATION; NONHUMAN; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTOPLAST; REAL TIME POLYMERASE CHAIN REACTION; STREPTOMYCES; STREPTOMYCES SAHACHIROI;

ANTINEOPLASTIC AGENTS; BIOSYNTHETIC PATHWAYS; CONJUGATION, GENETIC; GENE DELETION; GENE DOSAGE; GENE EXPRESSION PROFILING; GENE TRANSFER TECHNIQUES; GENES, BACTERIAL; GENETIC COMPLEMENTATION TEST; METABOLIC ENGINEERING; NAPHTHALENES; PEPTIDES; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; STREPTOMYCES; TRANSFORMATION, BACTERIAL;

STREPTOMYCES;

EID: 84870361595     PISSN: 03781097     EISSN: 15746968     Source Type: Journal    
DOI: 10.1111/1574-6968.12020     Document Type: Article

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