Chrysin: A histone deacetylase 8 inhibitor with anticancer activity and a suitable candidate for the standardization of chinese propolis

Journal of Agricultural and Food Chemistry

Volumn 60, Issue 47, 2012, Pages 11748-11758

  Sun, Li Ping ^a   Chen, Ai Ling ^b   Hung, Hsiao Chiao ^b   Chien, Yin Huan ^b   Huang, Jing Shi ^b   Huang, Chung Yang ^b   Chen, Yue Wen ^c   Chen, Chia Nan ^b  

^a INSTITUTE OF PLANT PROTECTION   (China)

^b NatureWise Biotech and Medicals Corporation   (Taiwan)

^c NATIONAL ILAN UNIVERSITY   (Taiwan)

Author keywords

Chinese propolis; chrysin; HDAC8 inhibitor; histone deacetylase inhibitor; standardization

Indexed keywords

ACTIVE INGREDIENTS; ANIMAL MODEL; ANTI-INFLAMMATORIES; ANTICANCER ACTIVITIES; ANTICANCER COMPOUNDS; ANTIVIRAL ACTIVITIES; BREAST CANCER CELLS; BROAD SPECTRUM; CAFFEIC ACID PHENETHYL ESTER; CHEMICAL COMPOSITIONS; CHINESE PROPOLIS; CHRYSIN; DRY WEIGHT; ENZYMATIC ACTIVITIES; FREE RADICAL SCAVENGING ACTIVITY; HDAC8 INHIBITOR; HEALTH FOODS; HISTONE DEACETYLASE INHIBITOR; HISTONE DEACETYLASES; IN-VITRO; IN-VITRO ANALYSIS; LOW LEVEL; NATURAL PRODUCTS; POTENT ACTIVE INGREDIENTS; TOTAL PHENOLIC CONTENT; TUMOR GROWTH;

PHENOLS; RAW MATERIALS; STANDARDIZATION; TUMORS;

FLAVONOIDS;

ANTINEOPLASTIC AGENT; CHRYSIN; ENZYME INHIBITOR; FLAVONOID; HDAC8 PROTEIN, HUMAN; HISTONE DEACETYLASE; PROPOLIS; REPRESSOR PROTEIN;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BREAST TUMOR; CHEMISTRY; CHINA; DRUG ANTAGONISM; DRUG SCREENING; FEMALE; HUMAN; ISOLATION AND PURIFICATION; MOUSE; NUDE MOUSE; STANDARD; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CHINA; ENZYME INHIBITORS; FEMALE; FLAVONOIDS; HISTONE DEACETYLASES; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; PROPOLIS; REPRESSOR PROTEINS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

ANIMALIA;

EID: 84870355205     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf303261r     Document Type: Article

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