Growth inhibitory activity of ethanol extracts of Chinese and Brazilian propolis in four human colon carcinoma cell lines

Oncology Reports

Volumn 22, Issue 2, 2009, Pages 349-354

  Ishihara, Masashi ^a,b   Naoi, Kuniko ^a   Hashita, Masanari ^a   Itoh, Yoshinori ^b   Suzui, Masumi ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b GIFU UNIVERSITY HOSPITAL   (Japan)

Author keywords

Apoptosis; Chemoprevention; Colon carcinoma; Propolis

Indexed keywords

ALCOHOL; CYCLIN DEPENDENT KINASE INHIBITOR 1; DIMETHYL SULFOXIDE; MESSENGER RNA; PROPOLIS; PROTEIN P53;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BRAZIL; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE REGULATION; CELL PROLIFERATION; CELL STRAIN CACO 2; CELL STRAIN HCT116; CELL STRAIN HT29; CHINA; COLON CARCINOMA; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; HUMANS; PROPOLIS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 68349112398     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000444     Document Type: Article

References (40)

1. Sporn MB and Suh N: Chemoprevention of cancer. Carcinogenesis 2: 525-530, 2000.
2. Khalil ML: Biological activity of bee propolis in health and disease. Asian Pac J Cancer Prev 7: 22-31, 2006.
3. Burdock GA: Review of the biological properties and toxicity of bee propolis (propolis). Food Chem Toxicol 36: 347-363, 1998.
4. Parkin DM: Global cancer statistics in the year 2000. Lancet Oncol 2: 533-543, 2001.
5. Wynder EL, Kajitani T, Ishikawa S, Dodo H and Takano A: Environmental factors of cancer of the colon and rectum. II. Japanese epidemiological data. Cancer 23: 1210-1220, 1969.
6. Reddy BS: Nutritional factors and colon cancer. Crit Rev Food Sci Nutr 35: 175-190, 1995.
7. Willett WC, Stampfer MJ, Colditz GA, Rosner BA and Speizer FE: Relation of meat, fat, and fiber intake to the risk of colon cancer in a prospective study among women. N Engl J Med 323: 1664-1672, 1990.
8. McWilliams RR and Erlichman C: Novel therapeutics in colorectal cancer. Dis Colon Rectum 48: 1632-1650, 2005.
9. Parkin DM, Bray F, Ferlay J and Pisani P: Global cancer statistics, 2002. CA Cancer J Cli 55: 74-108, 2005.
10. Sporn MB: Approaches to prevention of epithelial cancer during the preneoplastic period. Cancer Res 36: 2699-2702, 1976.
11. Suzui M, Inamine M, Kaneshiro T, et al: Indole-3-carbinol inhibits the growth of human colon carcinoma cells but enhances the tumor multiplicity and volume of azoxymethane-induced rat colon carcinogenesis. Int J Oncol 27: 1391-1399, 2005.
12. Suzui M, Sunagawa N, Chiba I, Moriwaki H and Yoshimi N: Acyclic retinoid, a novel synthetic retinoid, induces growth inhibition, apoptosis, and changes in mRNA expression of cell cycle- and differentiation-related molecules in human colon carcinoma cells. Int J Oncol 28: 1193-1199, 2006.
13. Joe AK, Liu H, Suzui M, Vural ME, Xiao D and Weinstein IB: Resveratrol induces growth inhibition, S-phase arrest, apoptosis, and changes in biomarker expression in several human cancer cell lines. Clin Cancer Res 8: 893-903, 2002.
14. Suzui M, Masuda M, Lim JT, Albanese C, Pestell RG and Weinstein IB: Growth inhibition of human hepatoma cells by acyclic retinoid is associated with induction of p21(CIP1) and inhibition of expression of cyclin D1. Cancer Res 62: 3997-4006, 2002.
15. Suzui M, Shimizu M, Masuda M, Lim JT, Yoshimi N and Weinstein IB: Acyclic retinoid activates retinoic acid receptor beta and induces transcriptional activation of p21(CIP1) in HepG2 human hepatoma cells. Mol Cancer Ther 3: 309-316, 2004.
16. Banskota AH, Nagaoka T, Sumioka LY, et al: Antiproliferative activity of the Netherlands propolis and its active principles in cancer cell lines. J Ethnopharmacol 80: 67-73, 2002.
17. Li F, Awale S, Tezuka Y and Kadota S: Cytotoxic constituents from Brazilian red propolis and their structure-activity relationship. Bioorg Med Chem 16: 5434-5440, 2008.
18. Russo A, Cardile V, Sanchez F, Troncoso N, Vanella A and Garbarino JA: Chilean propolis: antioxidant activity and antiproliferative action in human tumor cell lines. Life Sci 76: 545-558, 2004.
19. Katsube N, Iwashita K, Tsushida T, Yamaki K and Kobori M: Induction of apoptosis in cancer cells by Bilberry (Vaccinium myrtillus) and the anthocyanins. J Agric Food Chem 51: 68-75, 203.
20. Maoret JJ, Anini Y, Rouyer-Fessard C, Gully D and Laburthe M: Neurotensin and a non-peptide neurotensin receptor antagonist control human colon cancer cell growth in cell culture and in cells xenografted into nude mice. Int J Cancer 80: 448-454, 1999.
21. Usia T, Banskota AH, Tezuka Y, Midorikawa K, Matsushige K and Kadota S: Constituents of Chinese propolis and their antiproliferative activities. J Nat Prod 65: 673-676, 2002.
22. Ahn MR, Kunimasa K, Ohta T, et al: Suppression of tumorinduced angiogenesis by Brazilian propolis: major component artepillin C inhibits in vitro tube formation and endothelial cell proliferation. Cancer Lett 252: 235-243, 2007.
23. Li H, Kapur A, Yang JX, et al: Antiproliferation of human prostate cancer cells by ethanolic extracts of Brazilian propolis and its botanical origin. Int J Oncol 31: 601-606, 2007.
24. Chen CN, Weng MS, Wu CL and Lin JK: Comparison of radical scavenging activity, cytotoxic effects and apoptosis induction in human melanoma cells by Taiwanese propolis from different sources. Evid Based Complement Alternat Med 1: 175-185, 2004.
25. Chen CN, Wu CL and Lin JK: Apoptosis of human melanoma cells induced by the novel compounds propolin A and propolin B from Taiwanese propolis. Cancer Lett 245: 218-231, 2007.
26. Weinstein IB: Disorders in cell circuitry during multistage carcinogenesis: the role of homeostasis. Carcinogenesis 21: 857-864, 2000.
27. Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A and Oren M: Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature 352: 345-347, 1991.
28. Lin-Lee YC, Tatebe S, Savaraj N, Ishikawa T and Tien Kuo M: Differential sensitivities of the MRP gene family and gammaglutamylcysteine synthetase to prooxidants in human colorectal carcinoma cell lines with different p53 status. Biochem Pharmacol 61: 555-563, 2001.
29. Toscano F, Fajoui ZE, Gay F, et al: P53-mediated upregulation of DcR1 impairs oxaliplatin/TRAIL-induced synergistic antitumour potential in colon cancer cells. Oncogene 27: 4161-4171, 2008.
30. Hartwich A, Konturek SJ, Pierzchalski P, et al: Helicobacter pylori infection, gastrin, cyclooxygenase-2, and apoptosis in colorectal cancer. Int J Colorectal Dis 16: 202-210, 2001.
31. Colucci R, Blandizzi C, Ghisu N, Florio T and Del Tacca M: Somatostatin inhibits colon cancer cell growth through cyclooxygenase- 2 downregulation. Br J Pharmacol 155: 198-209, 2008.
32. Liu Q, Chan ST and Mahendran R: Nitric oxide induces cyclooxygenase expression and inhibits cell growth in colon cancer cell lines. Carcinogenesis 24: 637-642, 2003.
33. He YJ, Liu BH, Xiang DB, Qiao ZY, Fu T and He YH: Inhibitory effect of caffeic acid phenethyl ester on the growth of SW480 colorectal tumor cells involves beta-catenin associated signaling pathway down-regulation. World J Gastroenterol 12: 4981-4985, 2006.
34. Xiang D, Wang D, He Y, et al: Caffeic acid phenethyl ester induces growth arrest and apoptosis of colon cancer cells via the beta-catenin/ T-cell factor signaling. Anticancer Drugs 17: 753-762, 2006.
35. Hwang HJ, Park HJ, Chung HJ, et al: Inhibitory effects of caffeic acid phenethyl ester on cancer cell metastasis mediated by the down-regulation of matrix metalloproteinase expression in human HT1080 fibrosarcoma cells. J Nutr Biochem 17: 356-362, 2006.
36. Blonska M, Bronikowska J, Pietsz G, Czuba ZP, Scheller S and Krol W: Effects of ethanol extract of propolis (EEP) and its flavones on inducible gene expression in J774A.1 macrophages. J Ethnopharmacol 91: 25-30, 2004.
37. Woo KJ, Jeong YJ, Inoue H, Park JW and Kwon TK: Chrysin suppresses lipopolysaccharide-induced cyclooxygenase-2 expression through the inhibition of nuclear factor for IL-6 (NF-IL6) DNA-binding activity. FEBS Lett 579: 705-711, 2005.
38. Shimizu K, Das SK, Hashimoto T, et al: Artepillin C in Brazilian propolis induces G(0)/G(1) arrest via stimulation of Cip1/p21 expression in human colon cancer cells. Mol Carcinog 44: 293-299, 2005.
39. Yasui Y, Miyamoto S, Kim M, Kohno H, Sugie S and Tanaka T: Aqueous and ethanolic extract fractions from the Brazilian propolis suppress azoxymethane-induced aberrant crypt foci in rats. Oncol Rep 20: 493-499, 2008.
40. Shimizu K, Das SK, Baba M, Matsuura Y and Kanazawa K: Dietary artepillin C suppresses the formation of aberrant crypt foci induced by azoxymethane in mouse colon. Cancer Lett 240: 135-142, 2006.