Facile synthesis of chrysin-derivatives with promising activities as aromatase inhibitors

Natural Product Communications

Volumn 6, Issue 1, 2011, Pages 31-34

  Mohammed, Hamdoon A ^a   Ba, Lalla A ^a   Burkholz, Torsten ^a   Schumann, Elena ^a   Diesel, Britta ^a   Zapp, Josef ^a   Kiemer, Alexandra K ^a   Ries, Christina ^a   Hartmann, Rolf W ^a   Hosny, Mohammed ^b   Jacob, Claus ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b AL AZHAR UNIVERSITY   (Egypt)

Author keywords

Aromatase inhibition; Chrysin; Mannich reaction; Pyrano flavone

Indexed keywords

ACETYLENE DERIVATIVE; AMINOGLUTETHIMIDE; ANDROGEN; ANTINEOPLASTIC AGENT; AROMATASE; AROMATASE INHIBITOR; CHRYSIN; DICARBOXYLIC ACID DERIVATIVE; EPICATECHIN; ESTROGEN; FLAVONE DERIVATIVE; ISONITRILE DERIVATIVE; PYRANO FLAVONE; QUERCETIN; TAXIFOLIN; UNCLASSIFIED DRUG; FLAVONOID;

ARTICLE; BREAST CANCER; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; ENZYME INHIBITION; ENZYME SUBSTRATE; MANNICH REACTION; STRUCTURE ANALYSIS; SYNTHESIS; CHEMISTRY; HUMAN; IC 50; SOLUBILITY;

AROMATASE INHIBITORS; FLAVONOIDS; HUMANS; INHIBITORY CONCENTRATION 50; SOLUBILITY;

EID: 79953018741     PISSN: 1934578X     EISSN: 15559475     Source Type: Journal    
DOI: 10.1177/1934578x1100600108     Document Type: Article

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