Zinc finger motif-1 antagonizes PDGF-BB-induced growth and dedifferentiation of vascular smooth muscle cells

FASEB Journal

Volumn 26, Issue 12, 2012, Pages 4864-4875

  Cattaruzza, Marco ^a   Nogoy, Nicole ^a   Wojtowicz, Agnieszka ^a,b   Hecker, Markus ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Cellular phenotype control; Early growth response 1; Egr 1; Proliferation

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CALPONIN; COLLAGEN TYPE 1; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 8; OLIGONUCLEOTIDE; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN C FOS; PROTEIN C JUN; REPRESSOR PROTEIN; SMALL INTERFERING RNA; TENASCIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EGR 1; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG; ZINC FINGER MOTIF 1;

ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CELL MIGRATION; CHROMATIN IMMUNOPRECIPITATION; GENE EXPRESSION; HUMAN; HUMAN CELL; MUSCLE CONTRACTILITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

AMINO ACID SEQUENCE; BASE SEQUENCE; BLOTTING, WESTERN; CELL DEDIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; DNA-BINDING PROTEINS; GENE EXPRESSION; GREEN FLUORESCENT PROTEINS; HUMANS; MICROSCOPY, CONFOCAL; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PROTO-ONCOGENE PROTEINS C-SIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSCRIPTION FACTORS;

EID: 84870335619     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.12-210302     Document Type: Article

References (35)

1. Grazul-Bilska, A. T., Johnson, M. L., Bilski, J. J., Redmer, D. A., Reynolds, L. P., Abdullah, A., and Abdullah, K. M. (2003) Wound healing: the role of growth factors. Drugs Today 39, 787-800 (Pubitemid 37500405)
2. Nissen, L. J., Cao, R., Hedlund, E. M., Wang, Z., Zhao, X., Wetterskog, D., Funa. K., Bråkenhielm, E., and Cao, Y. (2007) Angiogenic factors FGF2 and PDGF-BB synergistically promote murine tumor neovascularization and metastasis. J. Clin. Invest. 117, 2766-2777 (Pubitemid 47529608)
3. Chen, C. N., Li, Y. S., Yeh, Y. T., Lee, P. L., Usami, S., Chien, S., and Chiu, J. J. (2006) Synergistic roles of platelet-derived growth factor-BB and interleukin-1 in phenotypic modulation of human aortic smooth muscle cells. Proc. Natl. Acad. Sci. U. S. A. 103, 2665-2670
4. Holycross, B. J., Blank, R. S., Thompson, M. M., Peach, M. J., and Owens, G. K. (1992) Platelet-derived growth factor-BB-induced suppression of smooth muscle cell differentiation. Circ. Res. 71, 1525-1532
5. Myllarniemi, M., Calderon, L., Lemstrom, K., Buchdunger, E., and Hayry, P. (1997) Inhibition of platelet-derived growth factor receptor tyrosine kinase inhibits vascular smooth muscle cell migration and proliferation FASEB J. 11, 1119-1126 (Pubitemid 27481435)
6. Guth, S., and Valcárcel, J. (2000) Kinetic role for mammalian SF1/BBP in spliceosome assembly and function after polypyrimidine tract recognition by U2AF. J. Biol. Chem. 275, 38059-38066 (Pubitemid 32004929)
7. Cattaruzza, M., Schäfer, K., and Hecker, M. (2002) Cytokine-induced down-regulation of zfm1/splicing factor 1 promotes smooth muscle cell proliferation. J. Biol. Chem. 277, 6582-6589 (Pubitemid 34968458)
8. Cattaruzza, M., Dimigen, C., Ehrenreich, H., and Hecker, M. (2000) Stretch-induced endothelin B receptor-mediated apoptosis in vascular smooth muscle cells. FASEB J. 14, 991-998 (Pubitemid 30241677)
9. Wójtowicz, A., Babu, S. S., Li, L., Gretz, N., Hecker, M., and Cattaruzza, M. (2010) Zyxin mediation of stretch-induced gene expression in human endothelial cells. Circ. Res. 107, 898-902
10. Morishita, R., Higaki, J., Tomita, N., and Ogihara, T. (1998) Application of transcription factor "decoy" strategy as means of gene therapy and study of gene expression in cardiovascular disease. Circ. Res. 82, 1023-1028 (Pubitemid 28249063)
11. Buchwald, A. B., Wagner, A. H., Webel, C., and Hecker, M. (2002) Decoy oligodeoxynucleotide against activator protein-1 reduces neointimal proliferation after coronary angioplasty in hypercholesterolemic minipigs. J. Am. Coll. Cardiol. 39, 732-738 (Pubitemid 34158173)
12. Wagner, S., Lynch, N. J., Walter, W., Schwaeble, W. J., and Loos, M. (2003) Differential expression of the murine mannose-binding lectins A and C in lymphoid and nonlymphoid organs and tissues. J. Immunol. 170, 1462-1465 (Pubitemid 36139515)
13. Bertolotti, A., Lutz, Y., Heard, D. J., Chambon, P., and Tora, L. (1996) hTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II. EMBO J. 15, 5022-5031 (Pubitemid 26315812)
14. Cartharius, K., Frech, K., Grote, K., Klocke, B., Haltmeier, M., Klingenhoff, A., Frisch, M., Bayerlein, M., and Werner, T. (2005) MatInspector and beyond: promoter analysis based on transcription factor binding sites. Bioinformatics 21, 2933-2942 (Pubitemid 40916416)
15. Kamimura, M., Bea, F., Akizawa, T., Katus, H. A., Kreuzer, J., and Viedt, C. (2004) Platelet-derived growth factor induces tissue factor expression in vascular smooth muscle cells via activation of Egr-1. Hypertension 44, 944-951 (Pubitemid 39577426)
16. Maehara, K., Oh-Hashi, K., and Isobe, K. I. (2001) Early growth-responsive-1-dependent manganese superoxide dismutase gene transcription mediated by platelet-derived growth factor. FASEB J. 15, 2025-2026
17. Xue, Y., Lim, S., Yang, Y., Wang, Z., Jensen, L. D., Hedlund, E. M., Andersson, P., Sasahara, M., Larsson, O., Galter, D., Cao, R., Hosaka, K., and Cao, Y. (2011) PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells. Nat. Med. 18, 100-110
18. Chang, H. J., Park, J. S., Kim, M. H., Hong, M. H., Kim, K. M., Kim, S. M., Shin, B. A., Ahn, B. W., and Jung, Y. D. (2006) Extracellular signal-regulated kinases and AP-1 mediate the up-regulation of vascular endothelial growth factor by PDGF in human vascular smooth muscle cells. Int. J. Oncol. 28, 135-141
19. Zhang, D., and Childs, G. (1998) Human ZFM1 protein is a transcriptional repressor that interacts with the transcription activation domain of stage-specific activator protein. J. Biol. Chem. 273, 6868-6877 (Pubitemid 28160350)
20. Zhang, D., Paley, A. J., and Childs, G. (1998) The transcriptional repressor ZFM1 interacts with and modulates the ability of EWS to activate transcription. J. Biol. Chem. 273, 18086-18091 (Pubitemid 28334724)
21. Bertolotti, A., Melot, T., Acker, J., Vigneron, M., Delattre, O., and Tora, L. (1998) EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes. Mol. Cell. Biol. 18, 1489-1497 (Pubitemid 28100914)
22. Christopher, P., and Mack, C. P. (2001) Signaling mechanisms that regulate smooth muscle cell differentiation. Arterioscler. Thromb. Vasc. Biol. 31, 1495-1505
23. Kaplan-Albuquerque, N., Van Putten, V., Weiser-Evans, M. C., and Nemenoff, R. A. (2005) Depletion of serum response factor by RNA interference mimics the mitogenic effects of platelet derived growth factor-BB in vascular smooth muscle cells. Circ. Res. 97, 427-433 (Pubitemid 41298172)
24. Long, X., Bell, R. D., Gerthoffer, W. T., Zlokovic, B. V., and Miano, J. M. (2008) Myocardin is sufficient for a smooth muscle-like contractile phenotype. Arterioscler. Thromb. Vasc. Biol. 28, 1505-1510
25. Wang, Z., Wang, D. Z., Teg Pipes, G. C., and Olson, E. N. (2003) Myocardin is a master regulator of smooth muscle gene expression. Proc. Natl. Acad. Sci. U. S. A. 100, 7129-7134 (Pubitemid 36706404)
26. Wada, H., Hasegawa, K., Morimoto, T., Kakita, T., Yanazume, T., Abe, M., and Sasayama, S. (2002) Calcineurin-GATA-6 pathway is involved in smooth muscle-specific transcription. J. Cell Biol. 156, 983-991 (Pubitemid 34839848)
27. Thomas, M. C., and Chiang, C. M. (2006) The general transcription machinery and general cofactors. Crit. Rev. Biochem. Mol. Biol. 41, 105-178
28. Bell, B., Scheer, E., and Tora, L. (2001) Identification of hTAF(II)80 delta links apoptotic signaling pathways to transcription factor TFIID function. Mol. Cell 8, 591-600 (Pubitemid 32946936)
29. Shitashige, M., Satow, R., Honda, K., Ono, M., Hirohashi, S., and Yamada, T. (2007) Increased susceptibility of Sf1(+/-) mice to azoxymethane-induced colon tumorigenesis. Cancer Sci. 98, 1862-1867 (Pubitemid 350002190)
30. Kitadai, Y., Sasaki, T., Kuwai, T., Nakamura, T., Bucana, C. D., and Fidler, I. J. (2006) Targeting the expression of platelet-derived growth factor receptor by reactive stroma inhibits growth and metastasis of human colon carcinoma. Am. J. Pathol. 169, 2054-2065 (Pubitemid 351181965)
31. Kono, S. A., Heasley, L. E., Doebele, R. C., and Camidge, D. R. (2012) Adding to the mix: fibroblast growth factor and platelet-derived growth factor receptor pathways as targets in non-small cell lung cancer. Curr. Cancer Drug Targets 12, 107-123
32. Marmur, J. D., Poon, M., Rossikhina, M., and Taubman, M. B. (1992) Induction of PDGF-responsive genes in vascular smooth muscle. Implications for the early response to vessel injury. Circulation 86, 53-60
33. Yamamoto, H., Crow, M., Cheng, L., Lakatta, E., and Kinsella, J. (1996) PDGF receptor-to-nucleus signaling of p91 (STAT1 alpha) transcription factor in rat smooth muscle cells. Exp. Cell Res. 222, 125-130 (Pubitemid 26046578)
34. Marumo, T., Schini-Kerth, V. B., Fisslthaler, B., and Busse, R. (1997) Platelet-derived growth factor-stimulated superoxide anion production modulates activation of transcription factor NF-kappaB and expression of monocyte chemoattractant protein 1 in human aortic smooth muscle cells. Circulation 96, 2361-2367
35. Hummerich, L., Müller, R., Hess, J., Kokocinski, F., Hahn, M., Fürstenberger, G., Mauch, C., Lichter, P., and Angel, P. (2006) Identification of novel tumour-associated genes differentially expressed in the process of squamous cell cancer development. Oncogene 25, 111-121 (Pubitemid 43050009)