Synergistic roles of platelet-derived growth factor-BB and interleukin-1β in phenotypic modulation of human aortic smooth muscle cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 8, 2006, Pages 2665-2670

  Chen, Cheng Nan ^a,b   Li, Yi Shuan J ^b   Yeh, Yi Ting ^a   Lee, Pei Ling ^a   Usami, Shunichi ^b   Chien, Shu ^b   Chiu, Jeng Jiann ^a,c  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Akt; mTOR; Signal transduction; Smooth muscle phenotype

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 6,7 DIMETHYL 2 PHENYLQUINOXALINE; AF 385; ALPHA ACTIN; CALPONIN; COLLAGEN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; MYOSIN HEAVY CHAIN; NEUTRALIZING ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN P70; S6 KINASE; UNCLASSIFIED DRUG; WORTMANNIN;

ADENOVIRUS; AORTA MEDIA; ARTICLE; CONTROLLED STUDY; DNA BINDING; DRUG POTENTIATION; HUMAN; HUMAN CELL; PHENOTYPE; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RIBOSOME;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AORTA; AORTIC DISEASES; ATHEROSCLEROSIS; CELLS, CULTURED; COLLAGEN; DRUG SYNERGISM; HUMANS; INTERLEUKIN-1; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PHENOTYPE; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PLATELET-DERIVED GROWTH FACTOR; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SERUM RESPONSE FACTOR;

ADENOVIRIDAE;

EID: 33644504832     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0510973103     Document Type: Article

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