Identification of two-pore domain potassium channels as potent modulators of osmotic volume regulation in human T lymphocytes

Biochimica et Biophysica Acta - Biomembranes

Volumn 1828, Issue 2, 2013, Pages 699-707

  Andronic, Joseph ^a   Bobak, Nicole ^b   Bittner, Stefan ^b   Ehling, Petra ^b   Kleinschnitz, Christoph ^a   Herrmann, Alexander M ^b   Zimmermann, Heiko ^c   Sauer, Markus ^a   Wiendl, Heinz ^b   Budde, Thomas ^b   Meuth, Sven G ^b   Sukhorukov, Vladimir L ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c FRAUNHOFER INSTITUTE FOR BIOMEDICAL ENGINEERING   (Germany)

Author keywords

Cell volumetry; K2P channels; Osmotic stress; Potassium channels; Regulatory volume decrease; T lymphocytes

Indexed keywords

ANANDAMIDE; POTASSIUM CHANNEL; POTASSIUM CHANNEL KV1.3; QUINIDINE; RUTHENIUM; TWO PORE DOMAIN POTASSIUM CHANNEL; TWO PORE DOMAIN POTASSIUM CHANNEL 18.1; TWO PORE DOMAIN POTASSIUM CHANNEL 3.1; TWO PORE DOMAIN POTASSIUM CHANNEL 5.1; TWO PORE DOMAIN POTASSIUM CHANNEL 9.1; UNCLASSIFIED DRUG;

ARTICLE; CD4+ T LYMPHOCYTE; CELL STIMULATION; CELL VOLUME; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOMODULATION; LYMPHOCYTE DIFFERENTIATION; MEMBRANE CURRENT; OSMOREGULATION; OSMOTIC STRESS; PHARMACOLOGICAL BLOCKING; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; REGULATORY MECHANISM; REGULATORY VOLUME DECREASE; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

BIOPHYSICS; CD4-POSITIVE T-LYMPHOCYTES; ELECTROPHYSIOLOGY; HOMEOSTASIS; HUMANS; INFLAMMATION; IONS; MICROSCOPY, VIDEO; OSMOSIS; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES; TIME FACTORS;

EID: 84870298117     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2012.09.028     Document Type: Article

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