A bronchofiberoscopy-associated outbreak of multidrug-resistant Acinetobacter baumannii in an intensive care unit in Beijing, China

BMC Infectious Diseases

Volumn 12, Issue , 2012, Pages

  Xia, Yukun ^a   Lu, CuiLing ^b   Zhao, Jingya ^a   Han, Gaige ^a,c   Chen, Yong ^a   Wang, Fang ^b   Yi, Bin ^b   Jiang, Guoqin ^a   Hu, Xiaohua ^a   Du, Xianfeng ^d   Wang, Zheng ^d   Lei, Hong ^b   Han, Xuelin ^a   Han, Li ^a  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^b 309TH HOSPITAL OF PLA   (China)

^c CENTRAL SOUTH UNIVERSITY   (China)

^d CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Bronchofiberscopy; Multidrug resistant Acinetobacter baumannii; Outbreak

Indexed keywords

CARBAPENEM; MULTIDRUG RESISTANCE PROTEIN; PALINDROMIC DNA; QUINOLONE DERIVATIVE;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTION; AGED; ARTICLE; BACTERIAL STRAIN; BRONCHOFIBERSCOPY; CHINA; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE CONTROL; DISEASE COURSE; EPIDEMIC; FEMALE; FIBEROPTIC BRONCHOSCOPY; FIBERSCOPE ENDOSCOPY; GENOTYPE; HUMAN; INFECTION CONTROL; INTENSIVE CARE UNIT; LUNG LAVAGE; MALE; POLYMERASE CHAIN REACTION; RISK FACTOR; TERTIARY HEALTH CARE;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTIONS; AGED; AGED, 80 AND OVER; BRONCHOSCOPY; CASE-CONTROL STUDIES; CHINA; DRUG RESISTANCE, MULTIPLE, BACTERIAL; FEMALE; HUMANS; INTENSIVE CARE UNITS; MALE; MIDDLE AGED;

EID: 84870292101     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-12-335     Document Type: Article

References (32)

1. Karageorgopoulos DE, Falagas ME. Current control and treatment of multidrug-resistant acinetobacter baumannii infections. Lancet Infect Dis 2008, 8(12):751-762. 10.1016/S1473-3099(08)70279-2, 19022191.
2. Villegas MV, Hartstein AI. Acinetobacter outbreaks, 1977-2000. Infect Control Hosp Epidemiol 2003, 24(4):284-295. 10.1086/502205, 12725359.
3. Struelens MJ, Carlier E, Maes N, Serruys E, Quint WG, van Belkum A. Nosocomial colonization and infection with multiresistant acinetobacter baumannii: outbreak delineation using DNA macrorestriction analysis and PCR-fingerprinting. J Hosp Infect 1993, 25(1):15-32. 10.1016/0195-6701(93)90005-K, 7901273.
4. Aygun G, Demirkiran O, Utku T, Mete B, Urkmez S, Yilmaz M, Yasar H, Dikmen Y, Ozturk R. Environmental contamination during a carbapenem-resistant acinetobacter baumannii outbreak in an intensive care unit. J Hosp Infect 2002, 52(4):259-262. 10.1053/jhin.2002.1300, 12473469.
5. Maragakis LL, Cosgrove SE, Song X, Kim D, Rosenbaum P, Ciesla N, Srinivasan A, Ross T, Carroll K, Perl TM. An outbreak of multidrug-resistant acinetobacter baumannii associated with pulsatile lavage wound treatment. JAMA 2004, 292(24):3006-3011. 10.1001/jama.292.24.3006, 15613669.
6. Song JY, Cheong HJ, Choi WS, Heo JY, Noh JY, Kim WJ. Clinical and microbiological characterization of carbapenem-resistant acinetobacter baumannii bloodstream infections. J Med Microbiol 2011, 60(Pt 5):605-611.
7. Wilks M, Wilson A, Warwick S, Price E, Kennedy D, Ely A, Millar MR. Control of an outbreak of multidrug-resistant acinetobacter baumannii-calcoaceticus colonization and infection in an intensive care unit (ICU) without closing the ICU or placing patients in isolation. Infect Control Hosp Epidemiol 2006, 27(7):654-658. 10.1086/507011, 16807837.
8. Mah MW, Memish ZA, Cunningham G, Bannatyne RM. Outbreak of acinetobacter baumannii in an intensive care unit associated with tracheostomy. Am J Infect Control 2001, 29(5):284-288. 10.1067/mic.2001.114232, 11584252.
9. Maslow JN, Glaze T, Adams P, Lataillade M. Concurrent outbreak of multidrug-resistant and susceptible subclones of acinetobacter baumannii affecting different wards of a single hospital. Infect Control Hosp Epidemiol 2005, 26(1):69-75. 10.1086/502489, 15693411.
10. Young LS, Sabel AL, Price CS. Epidemiologic, clinical, and economic evaluation of an outbreak of clonal multidrug-resistant acinetobacter baumannii infection in a surgical intensive care unit. Infect Control Hosp Epidemiol 2007, 28(11):1247-1254. 10.1086/521660, 17926275.
11. Dancer SJ. The role of environmental cleaning in the control of hospital-acquired infection. J Hosp Infect 2009, 73(4):378-385. 10.1016/j.jhin.2009.03.030, 19726106.
12. Koeleman JG, Parlevliet GA, Dijkshoorn L, Savelkoul PH, Vandenbroucke-Grauls CM. Nosocomial outbreak of multi-resistant acinetobacter baumannii on a surgical ward: epidemiology and risk factors for acquisition. J Hosp Infect 1997, 37(2):113-123. 10.1016/S0195-6701(97)90181-X, 9364260.
13. Munoz-Price LS, Zembower T, Penugonda S, Schreckenberger P, Lavin MA, Welbel S, Vais D, Baig M, Mohapatra S, Quinn JP, et al. Clinical outcomes of carbapenem-resistant acinetobacter baumannii bloodstream infections: study of a 2-state monoclonal outbreak. Infect Control Hosp Epidemiol 2010, 31(10):1057-1062. 10.1086/656247, 20715975.
14. Jang TN, Lee SH, Huang CH, Lee CL, Chen WY. Risk factors and impact of nosocomial acinetobacter baumannii bloodstream infections in the adult intensive care unit: a case-control study. J Hosp Infect 2009, 73(2):143-150. 10.1016/j.jhin.2009.06.007, 19716203.
15. Husni RN, Goldstein LS, Arroliga AC, Hall GS, Fatica C, Stoller JK, Gordon SM. Risk factors for an outbreak of multi-drug-resistant acinetobacter nosocomial pneumonia among intubated patients. Chest 1999, 115(5):1378-1382. 10.1378/chest.115.5.1378, 10334156.
16. Kolmos HJ, Lerche A, Kristoffersen K, Rosdahl VT. Pseudo-outbreak of pseudomonas aeruginosa in HIV-infected patients undergoing fiberoptic bronchoscopy. Scand J Infect Dis 1994, 26(6):653-657. 10.3109/00365549409008632, 7747087.
17. Rosengarten D, Block C, Hidalgo-Grass C, Temper V, Gross I, Budin-Mizrahi A, Berkman N, Benenson S. Cluster of pseudoinfections with burkholderia cepacia associated with a contaminated washer-disinfector in a bronchoscopy unit. Infect Control Hosp Epidemiol 2010, 31(7):769-771. 10.1086/653611, 20470036.
18. Chroneou A, Zimmerman SK, Cook S, Willey S, Eyre-Kelly J, Zias N, Shapiro DS, Beamis JF, Craven DE. Molecular typing of mycobacterium chelonae isolates from a pseudo-outbreak involving an automated bronchoscope washer. Infect Control Hosp Epidemiol 2008, 29(11):1088-1090. 10.1086/591451, 18937568.
19. Blanc DS, Parret T, Janin B, Raselli P, Francioli P. Nosocomial infections and pseudoinfections from contaminated bronchoscopes: two-year follow up using molecular markers. Infect Control Hosp Epidemiol 1997, 18(2):134-136. 10.1086/647569, 9120243.
20. DiazGranados CA, Jones MY, Kongphet-Tran T, White N, Shapiro M, Wang YF, Ray SM, Blumberg HM. Outbreak of pseudomonas aeruginosa infection associated with contamination of a flexible bronchoscope. Infect Control Hosp Epidemiol 2009, 30(6):550-555. 10.1086/597235, 19379099.
21. Srinivasan A, Wolfenden LL, Song X, Mackie K, Hartsell TL, Jones HD, Diette GB, Orens JB, Yung RC, Ross TL, et al. An outbreak of pseudomonas aeruginosa infections associated with flexible bronchoscopes. N Engl J Med 2003, 348(3):221-227. 10.1056/NEJMoa021808, 12529462.
22. Kirschke DL, Jones TF, Craig AS, Chu PS, Mayernick GG, Patel JA, Schaffner W. Pseudomonas aeruginosa and serratia marcescens contamination associated with a manufacturing defect in bronchoscopes. N Engl J Med 2003, 348(3):214-220. 10.1056/NEJMoa021791, 12529461.
23. Chinese Ministry of Health Chinese Guideline for Endoscopy Cleaning and Disinfection. Committee for Hospital Infection Control, Chinese Ministry of Health, Beijing 2004, http://www.moh.gov.cn/publicfiles/business/htmlfiles/mohyzs/pzcxx/200804/32051.ht, Chinese Ministry of Health.
24. Kallen AJ, Hidron AI, Patel J, Srinivasan A. Multidrug resistance among gram-negative pathogens that caused healthcare-associated infections reported to the national healthcare safety network, 2006-2008. Infect Control Hosp Epidemiol 2010, 31(5):528-531. 10.1086/652152, 20334552.
25. Orsi GB, Franchi C, Giordano A, Rocco M, Ferraro F, Mancini C, Venditti M. Multidrug-resistant acinetobacter baumannii outbreak in an intensive care unit. J Chemother 2008, 20(2):219-224.
26. Snelling AM, Gerner-Smidt P, Hawkey PM, Heritage J, Parnell P, Porter C, Bodenham AR, Inglis T. Validation of use of whole-cell repetitive extragenic palindromic sequence-based PCR (REP-PCR) for typing strains belonging to the acinetobacter calcoaceticus-acinetobacter baumannii complex and application of the method to the investigation of a hospital outbreak. J Clin Microbiol 1996, 34(5):1193-1202. 228981, 8727902.
27. Pashman J, Bradley EH, Wang H, Higa B, Fu M, Dembry LM. Promotion of hand hygiene techniques through use of a surveillance tool. J Hosp Infect 2007, 66(3):249-254. 10.1016/j.jhin.2007.03.018, 17544167.
28. Zhou H, Yang Q, Yu YS, Wei ZQ, Li LJ. Clonal spread of imipenem-resistant acinetobacter baumannii among different cities of china. J Clin Microbiol 2007, 45(12):4054-4057. 10.1128/JCM.00343-07, 2168573, 17942662.
29. Zhang JP, Zhu W, Tian SF, Chu YZ, Chen BY. Molecular characteristics and resistant mechanisms of imipenem-resistant acinetobacter baumannii isolates in shenyang, china. J Microbiol 2010, 48(5):689-694. 10.1007/s12275-010-0137-3, 21046349.
30. Playford EG, Craig JC, Iredell JR. Carbapenem-resistant acinetobacter baumannii in intensive care unit patients: risk factors for acquisition, infection and their consequences. J Hosp Infect 2007, 65(3):204-211. 10.1016/j.jhin.2006.11.010, 17254667.
31. Baran G, Erbay A, Bodur H, Onguru P, Akinci E, Balaban N, Cevik MA. Risk factors for nosocomial imipenem-resistant acinetobacter baumannii infections. Int J Infect Dis 2008, 12(1):16-21. 10.1016/j.ijid.2007.03.005, 17513154.
32. Jamal W, Salama M, Dehrab N, Al Hashem G, Shahin M, Rotimi VO. Role of tigecycline in the control of a carbapenem-resistant acinetobacter baumannii outbreak in an intensive care unit. J Hosp Infect 2009, 72(3):234-242. 10.1016/j.jhin.2009.03.023, 19493588.