Acinetobacter outbreaks, 1977-2000

Infection Control and Hospital Epidemiology

Volumn 24, Issue 4, 2003, Pages 284-295

  Villegas, Maria Virginia ^a   Hartstein, Alan I ^b  

^a CENTRO INTERNACIONAL DE ENTRENAMIENTO E INVESTIGACIONES MÉDICAS CIDEIM   (Colombia)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT;

ACINETOBACTER; ANTIBIOTIC RESISTANCE; ARTIFICIAL VENTILATION; BACTERIAL COLONIZATION; BACTERIAL SURVIVAL; BACTERIAL TRANSMISSION; BACTERIUM ISOLATE; BACTERIUM ISOLATION; CLUSTER ANALYSIS; ENDEMIC DISEASE; EPIDEMIC; GENOTYPE; HUMAN; INFECTION CONTROL; INFECTION PREVENTION; PUBLICATION; REVIEW; RISK FACTOR; SPECIES DIFFERENTIATION;

ACINETOBACTER; ACINETOBACTER INFECTIONS; DISEASE OUTBREAKS; DRUG RESISTANCE; HISTORY, 20TH CENTURY; HUMANS; INFECTION CONTROL; RISK FACTORS;

EID: 0038071600     PISSN: 0899823X     EISSN: None     Source Type: Journal    
DOI: 10.1086/502205     Document Type: Review

References (84)

1. Bergogne-Berezin E. The increasing significance of outbreaks of Acinetobacter spp.: the need for control and new agents. J Hosp Infect 1995;30(suppl):441-452.
2. Bergogne-Berezin E, Towner KL. Acinetobacter sp. as nosocomial pathogens: microbiological, clinical, and epidemiological features. Clin Microbiol Rev 1996;9:148-165.
3. Chastre J, Trouillet J. Problem pathogens (Pseudomonas aeruginosa and Acinetobacter). Semin Respir Infect 2000;15:287-298.
4. Fagon JY, Chastre J, Hance AJ, Montravers P, Novara A, Gibert C. Nosocomial pneumonia in ventilated patients: a cohort study evaluating attributable mortality and hospital stay. Am J Med 1993;94:281-288.
5. Lortholary O, Fagon JY, Hoi AB, et al. Nosocomial acquisition of multiresistant Acinetobacter baumannii: risk factors and prognosis. Clin Infect Dis 1995;20:790-796.
6. Weingarten CM, Rybak MJ, Jahns BE, Stevenson JG, Brown WJ, Levine DP. Evaluation of Acinetobacter baumannii infection and colonization, and antimicrobial treatment patterns in an urban teaching hospital. Pharmacotherapy 1999;19:1080-1085.
7. Sofianou DC, Constandinidis TC, Yannacou M, Anastasiou H, Sofianos E. Analysis of risk factors for ventilator-associated pneumonia in a multidisciplinary intensive care unit. Eur J Clin Microbiol Infect Dis 2000;19:460-463.
8. Ayats J, Corbella X, Ardanuy C, et al. Epidemiological significance of cutaneous, pharyngeal, and digestive Acinetobacter baumannii in ICU patients. J Hosp Infect 1997;37:287-295.
9. Wisplinghoff H, Edmond MB, Pfaller MA, Jones RN, Wenzel RP, Seifert H. Nosocomial bloodstream infections caused by Acinetobacter species in United States hospitals: clinical features, molecular epidemiology, and antimicrobial susceptibility. Clin Infect Dis 2000;31:690-697.
10. Beck-Sague C, Jarvis WR, Martone WJ. Outbreak investigations. In: Herwaldt LA, Decker MD, eds. A Practical Handbook for Hospital Epidemiologists. Thorofare, NJ: SLACK Incorporated; 1998:135-144.
11. Jarvis WR, Zaza S. Investigation of outbreaks. In: Mayhall CG, ed. Hospital Epidemiology and Infection Control, 2nd ed. Philadelphia: Lippincott William & Wilkins; 1999:111-120.
12. Wendt C, Herwaldt LA. Epidemics: identification and management. In: Wenzel RP, ed. Prevention and Control of Nosocomial Infections, 3rd ed. Baltimore: Lippincott Williams & Wilkins; 1997:175-213.
13. Smith PW, Massanari RM. Room humidifiers as the source of Acinetobacter infections. JAMA 1977;237:795-797.
14. Abrutyn E, Goodhart GL, Roos K, Anderson R, Buxton AL. Acinetobacter calcoaceticus outbreak associated with peritoneal dialysis. Am J Epidemiol 1978;107:328-335.
15. Castle M, Tenney JH, Weinstein MP, Eickhoff TC. Outbreak of a multiply resistant Acinetobacter in a surgical intensive care unit: epidemiology and control. Heart Lung 1978;7:641-644.
16. Irwin RS, Demers RR, Pratter MR, et al. An outbreak of Acinetobacter infection associated with the use of a ventilator spirometer. Respir Care 1980;25:232-237.
17. Reyes MP, Ganguly S, Fowler M, et al. Pyrogenic reactions after inadvertent infusion of endotoxin during cardiac catheterizations. Ann Intern Med 1980;93:32-35.
18. Lowes JA, Smith J, Tabaqchali S, Shaw EJ. Outbreak of infection in a urological ward. BMJ 1980;280:722.
19. Cunha BA, Gracewski J, Klimek JJ, McLaughlin JC, Quintiliani R. A common source outbreak of Acinetobacter pulmonary infections traced to Wright respirometers. Postgrad Med J 1980;56:169-172.
20. French GL, Casewell MW, Roncoroni AJ, Knight S, Phillips I. A hospital outbreak of antibiotic-resistant Acinetobacter anitratus: epidemiology and control. J Hosp Infect 1980;1:125-131.
21. Carlquist JF, Conti M, Burke JP. Progressive resistance in a single strain of Acinetobacter calcoaceticus recovered during a nosocomial outbreak. Am J Infect Control 1982;10:4348.
22. Kantor RJ, Carson LA, Graham DR, Petersen NJ, Favero MS. Outbreak of pyrogenic reactions at a dialysis center. Am J Med 1983;74:449-456.
23. Sherertz RJ, Sullivan ML. An outbreak of infections with Acinetobacter calcoaceticus in burn patients: contamination of patients' mattresses. J Infect Dis 1985;151:252-258.
24. Stone JW, Das BC. Investigation of an outbreak of infection with Acinetobacter calcoaceticus in a special care baby unit. J Hosp Infect 1986;7:4248.
25. Gervich DH, Grout CS. An outbreak of nosocomial Acinetobacter infections from humidifiers. Am J Infect Control 1985;13:210-215.
26. Allen KD, Green HT. Hospital outbreak of multi-resistant Acinetobacter anitratus: an airborne mode of spread? J Hosp Infect 1987;9:110-119.
27. Vandenbroucke-Grauls CM, Kerver AJ, Rommes JH, Jansen R, den Dekker C, VerhoefJ. Endemic Acinetobacter anitratus in a surgical intensive care unit: mechanical ventilators as reservoir. Eur J Clin Microbiol Infect Dis 1988;7:485-487.
28. Hartstein AI, Rashad AL, Liebler JM, et al. Multiple intensive care unit outbreak of Acinetobacter calcoaceticus subspecies anitratus respiratory infection and colonization associated with contaminated, reusable ventilator circuits and resuscitation bags. Am J Med 1988;85:624-631.
29. Sakata H, Fujita K, Maruyama S, Kakehashi H, Mori Y, Yoshiioka H. Acinetobacter calcoaceticus biovar anitratus septicaemia in a neonatal intensive care unit: epidemiology and control. J Hosp Infect 1989;14:15-22.
30. Crombach WH, Dijkshoorn L, Van Noort-Klaassen M, Niessen J, van Knippenberg-Gordebeke G. Control of an epidemic spread of a multi-resistant strain of Acinetobacter calcoaceticus in a hospital. Intensive Care Med 1989;15:166-170.
31. Buisson Y, Tran Van Nhieu G, Ginot L, et al. Nosocomial outbreaks due to amikacin-resistant, tobramycin-sensitive Acinetobacter species: correlation with amikacin usage. J Hosp Infect 1990;15:83-93.
32. Ng PC, Herrington RA, Beane CA, Ghoneim ATM, Dear PRF. An outbreak of Acinetobacter septicaemia in a neonatal intensive care unit. J Hosp Infect 1989;14:363-368.
33. Kelkar R, Gordon SM, Giri N, et al. Epidemic iatrogenic Acinetobacter spp. meningitis following administration of intrathecal methotrexate. J Hosp Infect 1989;14:233-243.
34. Beck-Sagué CM, Jarvis WR, Brook JH, et al. Epidemic bacteremia due to Acinetobacter baumannii in five intensive care units. Am J Epidemiol 1990;132:723-733.
35. Cefai C, Richards J, Gould FK, McPeake P. An outbreak of Acinetobacter respiratory tract infection resulting from incomplete disinfection of ventilatory equipment. J Hosp Infect 1990;15:177-182.
36. Contant J, Kemeny E, Oxley C, Perry E, Garber G. Investigation of an outbreak of Acinetobacter calcoaceticus var. anitratus infections in an adult intensive care unit. Am J Infect Control 1990;18:288-291.
37. Patterson JE, Vecchio J, Pantelick EL, et al. Association of contaminated gloves with transmission of Acinetobacter calcoaceticus var. anitratus in an intensive care unit. Am J Med 1991;91:479-483.
38. Struelens MJ, Carlier E, Maes N, Serruys E, Quint WGV, van Belkum A. Nosocomial colonization and infections with multiresistant Acinetobacter baumannii: outbreak delineation using DNA macrorestriction analysis and PCR-fingerprinting. J Hosp Infect 1993;25:15-32.
39. Ahmed J, Brutus A, D'Amato RF, Glatt AE. Acinetobacter calcoaceticus anitratus outbreak in the intensive care unit traced to a peak flow meter. Am J Infect Control 1994;22:319-321.
40. Tankovic J, Legrand P, De Gatimes G, Chemineau V, Brun-Buisson C, Duval J. Characterization of a hospital outbreak of imipenem-resistant Acinetobacter baumannii by phenotypic and genotypic typing methods. J Clin Microbiol 1994;2:2677-2681.
41. Go ES, Urban C, Burns J, et al. Clinical and molecular epidemiology of Acinetobacter infections sensitive only to polymyxin B and sulbactam. Lancet 1994;344:1329-1332.
42. Crowe M, Towner KJ, Humphreys H. Clinical and epidemiological features of an outbreak of Acinetobacter infection in an intensive therapy unit J Med Microbiol 1995;43:55-62
43. Lyytikäinen O, Köljalg S, Härmä M, Vuopio-Varkila J. Outbreak caused by two multi-resistant Acinetobacter baumannii clones in a burns unit: emergence of resistance to imipenem. J Hosp Infect 1995;31:41-53.
44. Scerpella EG, Wanger AR, Armitige L, Ericsson CD. Nosocomial outbreak caused by a multiresistant clone of Acinetobacter baumannii: results of the case-control and molecular epidemiologic investigations. Infect Control Hosp Epidemiol 1995;16:92-97.
45. Weernink A, Severin WP, Tjernberg I, Dijkshoorn L. Pillows, an unexpected source of Acinetobacter. J Hosp Infect 1995;29:189-199.
46. Debast SB, Meis JF, Melchers WJ, Hoogkamp-Korstanje JAA, Voss A. Use of interrepeat PCR fingerprinting to investigate an Acinetobacter baumannii outbreak in an intensive care unit. Scand J Infect Dis 1996;28:577-581.
47. Levin AS, Mendes CM, Sinto SI, et al. An outbreak of multiresistant Acinetobacter baumannii in a university hospital in Sao Paulo, Brazil. Infect Control Hosp Epidemiol 1996;17:366-368.
48. Snelling AM, Gerner-Smidt P, Hawkey PM, et al. Validation of use of whole-cell repetitive extragenic palindromic sequence-based PCR (REP-PCR) for typing strains belonging to the Acinetobacter calcoaceticus-Acinetobacter baumannii complex and application of the method to the investigation of a hospital outbreak. J Clin Microbiol 1996;34:1193-1202.
49. Riley TV, Webb SA, Cadwallader H, Briggs BD, Christiansen L, Bowman RA. Outbreak of gentamicin-resistant Acinetobacter baumannii in an intensive care unit: clinical, epidemiological and microbiological features. Pathology 1996;28:359-363.
50. Kaul R, Burt JA, Cork L, et al. Investigation of a multiyear multiple critical care unit outbreak due to relatively drug-sensitive Acinetobacter baumannii: risk factors and attributable mortality. J Infect Dis 1996;174:1279-1287.
51. Koeleman JG, Parlevliet GA, Dijkshoorn L, Savelkoul PHM, Vandenbroucke-Grauls CMJE. Nosocomial outbreak of multi-resistant Acinetobacter baumannii on a surgical ward: epidemiology and risk factors for acquisition. J Hosp Infect 1997;37:113-123.
52. Marques MB, Waites KB, Mangino JE, Hines BB, Moser SA. Genotypic investigation of multidrug-resistant Acinetobacter baumannii infections in a medical intensive care unit. J Hosp Infect 1995;37:125-135.
53. Bellamore E, Singh F, Pirrotta A, Greene VVH, Donelan SV. Outbreak of nosocomial Acinetobacter colonization possibly mediated by nebulizer techniques. Am J Infect Control 1997;25:162.
54. Dealler S. Nosocomial outbreak of multi-resistant Acinetobacter sp. on an intensive care unit: possible association with ventilation equipment. J Hosp Infect 1998;38:147-148.
55. McDonald LC, Walker M, Carson L, et al. Outbreak of Acinetobacter spp. bloodstream infections in a nursery associated with contaminated aerosols and air conditioners. Pediatr Infect Dis J 1998;17:716-722.
56. Cox MT, Roland WE, Dolan ME. Ventilator-related Acinetobacter outbreak in an intensive care unit. Mil Med 1998;163:389-391.
57. Villers D, Espaze E, Coste-Burel M, et al. Nosocomial Acinetobacter baumannii infections: microbiological and clinical epidemiology. Ann Intern Med 1998;129:182-189.
58. Biendo M, Laurans G, Lefebvre JF, Daoudi F, Eb F. Epidemiological study of an Acinetobacter baumannii outbreak by using a combination of antibiotyping and ribotyping. J Clin Microbiol 1999;37:2170-2175.
59. Pillay T, Pillay DG, Adhikary M, Pillay A, Sturm AW. An outbreak of neonatal infection with Acinetobacter linked to contaminated suction catheters. J Hosp Infect 1999;43:299-304.
60. Yoo JH, Choi JH, Shin WS, et al. Application of infrequent-restriction-site PCR to clinical isolates of Acinetobacter baumannii and Serratia marcescens. J Clin Microbiol 1999;37:3108-3112.
61. Kappstein I, Grundmann H, Haver T, Niemeyer C. Aerators as a reservoir of Acinetobacter junii: an outbreak of bacteremia in paediatric oncology patients. J Hosp Infect 2000;44:27-30.
62. D'Agata EM, Thayer V, Schaffner W. An outbreak of Acinetobacter baumannii: the importance of cross-transmission. Infect Control Hosp Epidemiol 2000;21:588-591.
63. Corbella X, Montero A, Pujol M, et al. Emergence and rapid spread of carbapenem resistance during a large and sustained hospital outbreak of multiresistant Acinetobacter baumannii. J Clin Microbiol 2000;38:4086-4095.
64. Reboli AC, Houston ED, Monteforte JS, Wood CA, Hamill RJ. Discrimination of epidemic and sporadic isolates of Acinetobacter baumannii by repetitive element PCR-mediated DNA fingerprinting. J Clin Microbiol 1994;32:2635-2640.
65. Seifert H, Schulze A, Baginski R, Pulverer G. Comparison of four different methods for epidemiologic typing of Acinetobacter baumannii. J Clin Microbiol 1994;32:1816-1819.
66. Seifert H, Gerner-Smidt P. Comparison of ribotyping and pulsed-field gel electrophoresis for molecular typing of Acinetobacter species. J Clin Microbiol 1995;33:1402-1407.
67. Webster CA, Towner KJ. Use of RAPD-ALF analysis for investigating the frequency of bacterial cross-transmission in an adult intensive care unit. J Hosp Infect 2000;44:254-260.
68. Simhon A, Rahav G, Shazberg G, Block C, Bercovier H, Shapiro M. Acinetobacter baumannii at a tertiary-care teaching hospital in Jerusalem, Israel. J Clin Microbiol 2001;39:389-391.
69. Hartstein AI, Morthland VH, Rourke MS Jr, et al. Plasmid DNA finger-printing of Acinetobacter calcoaceticus subspecies anitratus from intubated and mechanically ventilated patients. Infect Control Hosp Epidemiol 1990;11:531-538.
70. Niederman MS. Impact of antibiotic resistance on clinical outcomes and the cost of care. Crit Care Med 2001;29(suppl 4):N114-N120.
71. Kollef MH, Sherman G, Ward S, Fraser VJ. Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients. Chest 1999;115:462474.
72. Getschell-White SI, Donowitz LG, Groschel DH. The inanimate environment of an intensive care unit as a potential source of nosocomial bacteria: evidence for long survival of Acinetobacter calcoaceticus. Infect Control Hosp Epidemiol 1989;10:402-406.
73. Houang ETS, Chu YW, Leung CM, et al. Epidemiology and infection control implications of Acinetobacter spp. in Hong Kong. J Clin Microbiol 2001;39:228-234.
74. Musa EK, Desai N, Casewell MW. The survival of Acinetobacter calcoaceticus inoculated on fingertips and on formica. J Hosp Infect 1990;15:219-227.
75. Webster C, Towner KJ, Humphreys H. Survival of Acinetobacter on three clinically related inanimate surfaces. Infect Control Hosp Epidemiol 2000;21:246.
76. Peterson LR, Noskin GA. New technology for detection of multidrugresistant pathogens in the clinical microbiology laboratory. Emerg Infect Dis 2001;7:306-311.
77. Pfaller MA. Molecular approaches to diagnosing and managing infectious diseases: practicality and costs. Emerg Infect Dis 2001;7:312-318.
78. Cardoso CL, Pereira HH, Zequim JC, Guilhermetti M. Effectiveness of hand-cleansing agents for removing Acinetobacter baumannii strain from contaminated hands. Am J Infect Control 1999;27:327-331.
79. Klein BS, Perloff WH, Maki DG. Reduction of nosocomial infection during pediatric intensive care by protective isolation. N Engl J Med 1989;320:1714-1721
80. Hartstein AI, Denny MA, Morthland VH, LeMonte AM, Pfaller MA. Control of methicillin-resistant Staphylococcus aureus in a hospital and an intensive care unit. Infect Control Hosp Epidemiol 1995;16:405-411.
81. Weinstein RA. Controlling antimicrobial resistance in hospitals: infection control and use of antibiotics. Emerg Infect Dis 2001;7:188-192.
82. Khatib M, Jamaleddine G, Abdallah A, Ibrahim Y. Hand washing and use of gloves while managing patients receiving mechanical ventilation in the ICU. Chest 1999;116:172-175.
83. Singh N, Rogers P, Atwood CW, Wagener MM, Yu VL. Short-course empiric antibiotic therapy for patients with pulmonary infiltrates in the intensive care unit. Am J Resp Crit Care Med 2000;162:505-511.
84. Brooks SE, Walczak MA, Hameed R. Are we doing enough to contain Acinetobacter infections? Infect Control Hosp Epidemiol 2000;21:304.