Risk factors and impact of nosocomial Acinetobacter baumannii bloodstream infections in the adult intensive care unit: a case-control study

Journal of Hospital Infection

Volumn 73, Issue 2, 2009, Pages 143-150

  Jang, T N ^a,b   Lee, S H ^a   Huang, C H ^a,b   Lee, C L ^a   Chen, W Y ^a  

^a SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

^b FU JEN CATHOLIC UNIVERSITY   (Taiwan)

Author keywords

Acinetobacter baumannii; Bloodstream infection; Intensive care unit; Risk factors

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; CARBAPENEM DERIVATIVE; CEFEPIME; CEFTAZIDIME; CIPROFLOXACIN; IMIPENEM; LEVOFLOXACIN; MEROPENEM; PIPERACILLIN; PIPERACILLIN PLUS TAZOBACTAM; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SULTAMICILLIN;

ACINETOBACTER BAUMANNII; AGE; AGED; ANTIBIOTIC SENSITIVITY; ARTICLE; ARTIFICIAL VENTILATION; ASEPSIS; BACTERIAL COLONIZATION; BLOODSTREAM INFECTION; CASE CONTROL STUDY; CENTRAL VENOUS CATHETERIZATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; ENDOTRACHEAL TUBE; FEMALE; HAND WASHING; HEALTH CARE COST; HEALTH CARE PERSONNEL; HEALTH STATUS; HOSPITAL ADMISSION; HOSPITAL INFECTION; HUMAN; INTENSIVE CARE UNIT; INTRAVASCULAR CATHETER; LENGTH OF STAY; LOWER RESPIRATORY TRACT; LUNG INSUFFICIENCY; MAJOR CLINICAL STUDY; MALE; MINIMUM INHIBITORY CONCENTRATION; MORTALITY; RESPIRATORY FAILURE; RISK FACTOR; SEX DIFFERENCE; SURVIVAL RATE; TAIWAN;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTIONS; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; BACTEREMIA; CASE-CONTROL STUDIES; CROSS INFECTION; DISEASE OUTBREAKS; FEMALE; HUMANS; INCIDENCE; INTENSIVE CARE UNITS; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; RISK FACTORS; TAIWAN;

EID: 69749084388     PISSN: 01956701     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhin.2009.06.007     Document Type: Article

References (29)

1. Getchell-White S.I., Donowitz L.G., and Groschel D.H. The inanimate environment of an intensive care unit as a potential source of nosocomial bacteria: evidence for long survival of Acinetobacter calcoaceticus. Infect Control Hosp Epidemiol 10 (1989) 402-407
2. Valles J., Leon C., Alvarez-Lerma F., et al. Nosocomial bacteremia in critically ill patients: a multi-center study evaluating epidemiology and prognosis. Clin Infect Dis 24 (1997) 387-395
3. Hsueh P.R., Teng L.J., Chen C.Y., et al. Pan-drug-resistant Acinetobacter baumannii causing nosocomial infections in a university hospital, Taiwan. Emerg Infect Dis 8 (2002) 827-832
4. Allen D.M., and Hartman B.J. Acinetobacter species. In: Mandell G.L., Bennett J.E., and Dolin R. (Eds). Principles and practice of infectious diseases. 6th edn. (2005), Churchill Livingstone, Philadelphia 2632-2636
5. Chen Y.C., Chang S.C., Hsieh W.C., and Luh K.T. Acinetobacter calcoaceticus bacteremia: analysis of 48 cases. J Formos Med Assoc 90 (1991) 958-963
6. Smego R.A. Endemic nosocomial Acinetobacter calcoaceticus bacteremia: clinical significance, treatment, and prognosis. Arch Intern Med 145 (1985) 2174-2179
7. Grupper M., Sprecher H., Mashiach T., and Finkelstein R. Attributable mortality of nosocomial Acinetobacter bacteremia. Infect Control Hosp Epidemiol 28 (2007) 293-298
8. Garner J.S., Jarvis W.R., Emori T.G., Horan T.C., and Hughes J.M. CDC definitions for nosocomial infections. Am J Infect Control 16 (1988) 128-140
9. Fagon J.Y., Chastre J., Novara A., Medioni P., and Gibert C. Characterization of intensive care unit patients using a model based on the presence or absence of organ dysfunctions and/or infection: the ODIN model. Intensive Care Med 19 (1993) 137-144
10. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial disk susceptibility testing: 16th informational supplement. M100-S17 (2007), CLSI, Wayne, PA
11. Cefai C., Richards J., Gould F.K., and McPeake P. An outbreak of Acinetobacter respiratory tract infection resulting from incomplete disinfection of ventilatory equipment. J Hosp Infect 15 (1990) 177-182
12. Tilley P.A.G., and Roberts F.J. Bacteremia with Acinetobacter species: risk factors and prognosis in different clinical settings. Clin Infect Dis 18 (1994) 896-900
13. Siegman-Igra Y., Bar-Yosef S., Gorea A., and Avram J. Nosocomial Acinetobacter meningitis secondary to invasive procedures: report of 25 cases and review. Clin Infect Dis 17 (1993) 843-849
14. Sherertz R.J., and Sullivan M.L. An outbreak of infections with Acinetobacter calcoaceticus in burn patients: contamination of patients' mattresses. J Infect Dis 151 (1985) 252-259
15. Jerassy Z., Yinnon A.M., Mazouz-Cohen S., et al. Prospective hospital-wide studies of 505 patients with nosocomial bacteraemia in 1997 and 2002. J Hosp Infect 62 (2006) 230-236
16. Garnacho-Montero J., Ortiz-Leyba C., Fernandez-Hinojosa E., et al. Acinetobacter baumannii ventilator-associated pneumonia: epidemiological and clinical findings. Intensive Care Med 31 (2005) 649-655
17. Lortholary O., Fagon J.Y., Hoi A.B., et al. Nosocomial acquisition of multiresistant Acinetobacter baumannii: risk factors and prognosis. Clin Infect Dis 20 (1995) 790-796
18. Mulin B., Talon D., Viel J.F., et al. Risk factors for nosocomial colonization with multiresistant Acinetobacter baumannii. Eur J Clin Microbiol Infect Dis 14 (1995) 569-576
19. Peacock J.E., Sorrell L., Sottile F.D., Price L.E., and Rutala W.A. Nosocomial respiratory tract colonization and infection with aminoglycoside-resistant Acinetobacter calcoaceticus var. anitratus: epidemiologic characteristics and clinical significance. Infect Control Hosp Epidemiol 9 (1988) 302-308
20. Garmendia J.L.G., Leyba O.C., Montero J.G., et al. Risk factors for Acinetobacter baumannii nosocomial bacteremia in critically ill patients: a cohort study. Clin Infect Dis 33 (2001) 939-946
21. Wisplinghoff H., Perbix W., and Siefert H. Risk factors for nosocomial bloodstream infections due to Acinetobacter baumannii: a case-control study of adult burn patients. Clin Infect Dis 28 (1999) 59-66
22. Chen H.P., Chen T.L., Lai C.H., et al. Predictors of mortality in Acinetobacter baumannii bacteremia. J Microbiol Immunol Infect 38 (2005) 127-136
23. Seifert H., Strate A., and Pulverer G. Nosocomial bacteremia due to Acinetobacter baumannii. Clinical features, epidemiology, and predictors of mortality. Medicine 74 (1995) 340-349
24. Rolston K., Guan Z., Bodey G.P., and Elting L. Acinetobacter calcoaceticus septicemia in patients with cancer. South Med J 78 (1985) 647-651
25. Jang T.N., Kuo B.I.T., Shen S.H., et al. Nosocomial gram-negative bacteremia in critically ill patients: epidemiologic characteristics and prognostic factors in 147 episodes. J Formos Med Assoc 98 (1999) 465-473
26. Blot S., Vandewoude K., and Colardyn F. Nosocomial bacteremia involving Acinetobacter baumannii in critically ill patients: a matched cohort study. Intensive Care Med 29 (2003) 471-475
27. Pittet D., Tarara D., and Wenzel R.P. Nosocomial bloodstream infection in critically ill patients: excess length of stay, extra costs, and attributable mortality. J Am Med Assoc 271 (1994) 1598-1601
28. Wareham D.W., Bean D.C., Khanna P., et al. Bloodstream infection due to Acinetobacter spp: epidemiology, risk factors and impact of multi-drug resistance. Eur J Clin Microbiol Infect Dis 27 (2008) 607-612
29. Lee N.Y., Lee H.C., Ko N.Y., et al. Clinical and economic impact of multidrug resistance in nosocomial Acinetobacter baumannii bacteremia. Infect Control Hosp Epidemiol 28 (2007) 713-719