Evaluation of the functional importance of organic cation transporters on the ocular disposition of its intravitreally injected substrate in rabbits

Current Eye Research

Volumn 37, Issue 12, 2012, Pages 1127-1135

  Nirmal, Jayabalan ^a   Velpandian, Thirumurthy ^a   Singh, Sundararajan Baskar ^b   Ranjan Biswas, Nihar ^b   Azad, Rajvardhan ^a   Thavaraj, Vasantha ^c   Mittal, Gaurav ^d   Bhatnagar, Aseem ^d   Ghose, Supriyo ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^c Indian Council for Medical Research   (India)

^d INSTITUTE OF NUCLEAR MEDICINE AND ALLIED SCIENCES   (India)

Author keywords

Intravitreal; Ocular; Organic cation transporters; Pharmacokinetics

Indexed keywords

ORGANIC CATION TRANSPORTER; QUINIDINE SULFATE; TECHNETIUM 99M; TETRYLAMMONIUM CHLORIDE;

ANIMAL EXPERIMENT; AQUEOUS HUMOR; AREA UNDER THE CURVE; ARTICLE; BLOOD RETINA BARRIER; CHOROID; CLINICAL EVALUATION; CONJUNCTIVA; CONTROLLED STUDY; CORNEA; EXPERIMENTAL RABBIT; EYE; FEMALE; GAMMA SCINTIGRAPHY; IN VIVO STUDY; IRIS; LENS; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NONHUMAN; PRIORITY JOURNAL; RETINA; SCLERA; TISSUE DISTRIBUTION; VITREOUS BODY;

ANIMALS; BLOOD-RETINAL BARRIER; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; INTRAVITREAL INJECTIONS; MALE; ORGANIC CATION TRANSPORT PROTEINS; POTASSIUM CHANNEL BLOCKERS; QUINIDINE; RABBITS; TANDEM MASS SPECTROMETRY; TECHNETIUM; TETRAETHYLAMMONIUM; VITREOUS BODY; VOLTAGE-GATED SODIUM CHANNEL BLOCKERS;

EID: 84870272605     PISSN: 02713683     EISSN: 14602202     Source Type: Journal    
DOI: 10.3109/02713683.2012.715715     Document Type: Article

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