Development and validation of a highly sensitive LC-MS/MS method for organic cation transporter (OCT) substrate tetraethylammonium (TEA) in rabbits

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 879, Issue 9-10, 2011, Pages 585-590

  Nirmal, Jayabalan ^a   Velpandian, Thirumurthy ^a   Singh, Sundararajan Baskar ^b   Biswas, Nihar Ranjan ^b   Thavaraj, Vasantha ^c   Azad, Rajvardhan ^a   Ghose, Supriyo ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^c Indian Council for Medical Research   (India)

Author keywords

HILIC; LC MS MS; OCT; Tandem mass spectroscopy; Tetraethylammonium

Indexed keywords

HILIC; LC-MS/MS; OCT; TANDEM MASS SPECTROSCOPY; TETRAETHYLAMMONIUM;

ACETONITRILE; ELECTROSPRAY IONIZATION; FORMIC ACID; HYDROPHILICITY; IONIC LIQUIDS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; POSITIVE IONS;

AMMONIUM COMPOUNDS;

TETRYLAMMONIUM;

ACCURACY; ARTICLE; DRUG BLOOD LEVEL; ELECTROSPRAY MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; QUALITY CONTROL; RABBIT; SENSITIVITY ANALYSIS; VALIDATION PROCESS;

ANIMALS; CHROMATOGRAPHY, LIQUID; DRUG STABILITY; LINEAR MODELS; MODELS, BIOLOGICAL; MODELS, CHEMICAL; OPHTHALMIC SOLUTIONS; ORGANIC CATION TRANSPORT PROTEINS; RABBITS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; TETRAETHYLAMMONIUM;

ORYCTOLAGUS CUNICULUS;

EID: 79952193994     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2011.01.019     Document Type: Article

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