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Volumn 115, Issue 6, 2012, Pages 1457-1466

The local peripheral antihyperalgesic effect of levetiracetam and its mechanism of action in an inflammatory pain model

Author keywords

[No Author keywords available]

Indexed keywords

1,3,4,5',6,6',7,12B OCTAHYDRO 1',3' DIMETHYL 2H SPIRO[BENZO[B]FURO[2,3 A]QUINOLIZINE 2,4' PYRIMIDINE] 2' ONE; 2 (1 METHYL 2 ISOINDOLINYLMETHYL) 2 IMIDAZOLINE; 4 AMINOBUTYRIC ACID RECEPTOR; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADRENERGIC RECEPTOR; BICUCULLINE; CAFFEINE; CARRAGEENAN; DEXTRO PHENYLALANYLCYSTEINYLTYROSYL DEXTRO TRYPTOPHYLARGINYLTHREONYLPENICILLAMINYLTHREONINAMIDE 2,7 DISULFIDE; ETIRACETAM; METHYSERGIDE; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; NALOXONE; OPIATE RECEPTOR; PURINERGIC RECEPTOR; SEROTONIN RECEPTOR; YOHIMBINE;

EID: 84870243260     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ANE.0b013e31826c7fc2     Document Type: Article
Times cited : (40)

References (43)
  • 4
    • 77956027437 scopus 로고    scopus 로고
    • The antihyperalgesic effect of levetiracetam in an infammatory model of pain in rats: Mechanism of action
    • Micov A, Tomíc M, Popovíc B, Stepanovíc- Petrovíc R. The antihyperalgesic effect of levetiracetam in an infammatory model of pain in rats: mechanism of action. Br J Pharmacol 2010;161:384-92
    • (2010) Br J Pharmacol , vol.161 , pp. 384-392
    • Micov, A.1    Tomíc, M.2    Popovíc, B.3    Stepanovíc- Petrovíc, R.4
  • 5
    • 65449130768 scopus 로고    scopus 로고
    • Pilot study to evaluate the effcacy and tolerability of levetiracetam (Keppra) in treatment of patients with trigeminal neuralgia
    • Jorns TP, Johnston A, Zakrzewska JM. Pilot study to evaluate the effcacy and tolerability of levetiracetam (Keppra) in treatment of patients with trigeminal neuralgia. Eur J Neurol 2009;16:740-4
    • (2009) Eur J Neurol , vol.16 , pp. 740-744
    • Jorns, T.P.1    Johnston, A.2    Zakrzewska, J.M.3
  • 6
    • 69349096054 scopus 로고    scopus 로고
    • The role of the neuromodulators in the preventive treatment of migraine
    • Pascual-Gómez J. The role of the neuromodulators in the preventive treatment of migraine. Rev Neurol 2009;49:25-32
    • (2009) Rev Neurol , vol.49 , pp. 25-32
    • Pascual-Gómez, J.1
  • 8
    • 84867737203 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of levetiracetam in central pain in multiple sclerosis
    • Falah M, Madsen C, Holbech JV, Sindrup SH. A randomized, placebo-controlled trial of levetiracetam in central pain in multiple sclerosis. Eur J Pain 2012;16:860-9
    • (2012) Eur J Pain , vol.16 , pp. 860-869
    • Falah, M.1    Madsen, C.2    Holbech, J.V.3    Sindrup, S.H.4
  • 9
    • 0037373297 scopus 로고    scopus 로고
    • Topical and peripherally acting analgesics
    • Sawynok J. Topical and peripherally acting analgesics. Pharmacol Rev 2003;55:1-20
    • (2003) Pharmacol Rev , vol.55 , pp. 1-20
    • Sawynok, J.1
  • 10
    • 0041766163 scopus 로고    scopus 로고
    • Carrageenan-induced Paw Edema in the Rat and Mouse
    • Winyard PG, Willoughby DA, eds Totowa, NJ: Humana Press Inc.
    • Morris CJ. Carrageenan-induced paw edema in the rat and mouse. In: Winyard PG, Willoughby DA, eds. Infammation Protocols (Methods in Molecular Biology). Vol 225. Totowa, NJ: Humana Press Inc., 2003:115-23
    • (2003) Infammation Protocols (Methods in Molecular Biology) , vol.225 , pp. 115-123
    • Morris, C.J.1
  • 11
    • 84960959252 scopus 로고
    • A method for measurement of analgesic activity on infamed tissue
    • Randall LO, Selitto JJ. A method for measurement of analgesic activity on infamed tissue. Arch Int Pharmacodyn Ther 1957;111:409-19
    • (1957) Arch Int Pharmacodyn Ther , vol.111 , pp. 409-419
    • Randall, L.O.1    Selitto, J.J.2
  • 12
    • 4444357183 scopus 로고    scopus 로고
    • The anti-hyperalgesic effects of carba-mazepine and oxcarbazepine are attenuated by treatment with adenosine receptor antagonists
    • Tomíc MA, Vučković SM, Stepanovíc- Petrovíc RM, Ugrešić N, Prostran MS, Bošković B. The anti-hyperalgesic effects of carba-mazepine and oxcarbazepine are attenuated by treatment with adenosine receptor antagonists. Pain 2004;111:253-60
    • (2004) Pain , vol.111 , pp. 253-260
    • Tomíc, M.A.1    Vučković, S.M.2    Stepanovíc- Petrovíc, R.M.3    Ugrešić, N.4    Prostran, M.S.5    Boš ković, B.6
  • 16
    • 0141992215 scopus 로고    scopus 로고
    • Potent analgesic effects of anticonvulsants on peripheral thermal nociception in rats
    • Todorovíc SM, Rastogi AJ, Jevtovíc-Todorovíc V. Potent analgesic effects of anticonvulsants on peripheral thermal nociception in rats. Br J Pharmacol 2003;140:255-60
    • (2003) Br J Pharmacol , vol.140 , pp. 255-260
    • Todorovíc, S.M.1    Rastogi, A.J.2    Jevtovíc-Todorovíc, V.3
  • 18
    • 33645845731 scopus 로고    scopus 로고
    • Peripheral antinociception by carba-mazepine in an infammatory mechanical hyperalgesia model in the rat: A new target for carbamazepine?
    • Vučković S, Tomíc M, Stepanovíc- Petrovíc R, Ugrešić N, Prostran M, Boškovíc B. Peripheral antinociception by carba-mazepine in an infammatory mechanical hyperalgesia model in the rat: a new target for carbamazepine? J Pharmacol Sci 2006;100:310-4
    • (2006) J Pharmacol Sci , vol.100 , pp. 310-314
    • Vučković, S.1    Tomíc, M.2    Stepanovíc- Petrovíc, R.3    Ugrešić, N.4    Prostran, M.5    Boškovíc, B.6
  • 19
    • 84877816815 scopus 로고    scopus 로고
    • The mechanisms of antihyperalgesic effect of topiramate in a rat model of infammatory hyperalgesia
    • Dec 5. doi:10.1111/j.1472-8206.2011.01018.x. [Epub ahead of print]
    • Paranos SL, Tomíc MA, Micov AM, Stepanović-Petrovíc RM. The mechanisms of antihyperalgesic effect of topiramate in a rat model of infammatory hyperalgesia. Fundam Clin Pharmacol 2011 Dec 5. doi:10.1111/j.1472- 8206.2011.01018.x. [Epub ahead of print]
    • (2011) Fundam Clin Pharmacol
    • Paranos, S.L.1    Tomíc, M.A.2    Micov, A.M.3    Stepanović- Petrovíc, R.M.4
  • 23
    • 0036193683 scopus 로고    scopus 로고
    • Selective blockade of N-type calcium channels by levetiracetam
    • Lukyanetz EA, Shkryl VM, Kostyuk PG. Selective blockade of N-type calcium channels by levetiracetam. Epilepsia 2002;43:9-18
    • (2002) Epilepsia , vol.43 , pp. 9-18
    • Lukyanetz, E.A.1    Shkryl, V.M.2    Kostyuk, P.G.3
  • 24
    • 7944236620 scopus 로고    scopus 로고
    • Differential sensitivity of N-and P/Q-type Ca2+ channel currents to a mu opioid in isolec-tin B4-positive and-negative dorsal root ganglion neurons
    • Wu ZZ, Chen SR, Pan HL. Differential sensitivity of N-and P/Q-type Ca2+ channel currents to a mu opioid in isolec-tin B4-positive and-negative dorsal root ganglion neurons. J Pharmacol Exp Ther 2004;311:939-47
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 939-947
    • Wu, Z.Z.1    Chen, S.R.2    Pan, H.L.3
  • 25
    • 0026502169 scopus 로고
    • Calcium current variation between acutely isolated adult rat dorsal root ganglion neurons of different size
    • Scroggs RS, Fox A P. Calcium current variation between acutely isolated adult rat dorsal root ganglion neurons of different size. J Physiol 1992;445:639-58
    • (1992) J Physiol , vol.445 , pp. 639-658
    • Scroggs, R.S.1    Fox, A.P.2
  • 26
    • 43949174602 scopus 로고
    • The relationship between new ion channels and ectopic discharges from a region of nerve injury
    • Xie YK, Xiao WH, Li HQ. The relationship between new ion channels and ectopic discharges from a region of nerve injury. Sci China B 1993;36:68-74
    • (1993) Sci China B , vol.36 , pp. 68-74
    • Xie, Y.K.1    Xiao, W.H.2    Li, H.Q.3
  • 27
    • 0032504620 scopus 로고    scopus 로고
    • Effect of subcutaneous administration of calcium channel blockers on nerve injury-induced hyperal-gesia
    • White DM, Cousins MJ. Effect of subcutaneous administration of calcium channel blockers on nerve injury-induced hyperal-gesia. Brain Res 1998;801:50-8
    • (1998) Brain Res , vol.801 , pp. 50-58
    • White, D.M.1    Cousins, M.J.2
  • 28
    • 0036277865 scopus 로고    scopus 로고
    • Descending control of pain
    • Millan MJ. Descending control of pain. Prog Neurobiol 2002;66:355-474
    • (2002) Prog Neurobiol , vol.66 , pp. 355-474
    • Millan, M.J.1
  • 29
    • 33749353714 scopus 로고    scopus 로고
    • The effects of alpha2-adreno-ceptor agents on anti-hyperalgesic effects of carbamazepine and oxcarbazepine in a rat model of infammatory pain
    • Vučković SM, Tomíc MA, Stepanovíc- Petrovíc RM, Ugrešić N, Prostran MS, Bošković B. The effects of alpha2-adreno-ceptor agents on anti-hyperalgesic effects of carbamazepine and oxcarbazepine in a rat model of infammatory pain. Pain 2006;125:10-9
    • (2006) Pain , vol.125 , pp. 10-19
    • Vučković, S.M.1    Tomíc, M.A.2    Stepanovíc- Petrovíc, R.M.3    Ugrešić, N.4    Prostran, M.S.5    Boš ković, B.6
  • 30
    • 0028932390 scopus 로고
    • Peripheral nocicep-tive effects of alpha 2-adrenergic receptor agonists in the rat
    • Khasar SG, Green PG, Chou B, Levine JD. Peripheral nocicep-tive effects of alpha 2-adrenergic receptor agonists in the rat. Neuroscience 1995;66:427-32
    • (1995) Neuroscience , vol.66 , pp. 427-432
    • Khasar, S.G.1    Green, P.G.2    Chou, B.3    Levine, J.D.4
  • 31
    • 0030447315 scopus 로고    scopus 로고
    • Interactions of sympathetic and primary afferent neurons following nerve injury and tissue trauma
    • Jänig W, Levine JD, Michaelis M. Interactions of sympathetic and primary afferent neurons following nerve injury and tissue trauma. Prog Brain Res 1996;113:161-84
    • (1996) Prog Brain Res , vol.113 , pp. 161-184
    • Jänig, W.1    Levine, J.D.2    Michaelis, M.3
  • 32
    • 0031029783 scopus 로고    scopus 로고
    • Multiple receptors involved in peripheral alpha 2, mu, and A1 antinociception, tolerance, and withdrawal
    • Aley KO, Levine JD. Multiple receptors involved in peripheral alpha 2, mu, and A1 antinociception, tolerance, and withdrawal. J Neurosci 1997;17:735-44
    • (1997) J Neurosci , vol.17 , pp. 735-744
    • Aley, K.O.1    Levine, J.D.2
  • 34
    • 0142185330 scopus 로고    scopus 로고
    • Distribution of antinociceptive adenosine A1 receptors in the spinal cord dorsal horn, and relationship to primary afferents and neuronal subpopulations
    • Schulte G, Robertson B, Fredholm BB, DeLander GE, Shortland P, Molander C. Distribution of antinociceptive adenosine A1 receptors in the spinal cord dorsal horn, and relationship to primary afferents and neuronal subpopulations. Neuroscience 2003;121:907-16
    • (2003) Neuroscience , vol.121 , pp. 907-916
    • Schulte, G.1    Robertson, B.2    Fredholm, B.B.3    Delander, G.E.4    Shortland, P.5    Molander, C.6
  • 35
    • 0029590279 scopus 로고
    • Opioid and adenosine peripheral antinociception are subject to tolerance and withdrawal
    • Aley KO, Green PG, Levine JD. Opioid and adenosine peripheral antinociception are subject to tolerance and withdrawal. J Neurosci 1995;15:8031-8
    • (1995) J Neurosci , vol.15 , pp. 8031-8038
    • Aley, K.O.1    Green, P.G.2    Levine, J.D.3
  • 36
    • 0002733988 scopus 로고    scopus 로고
    • Peripheral antihyperalgesic effects by adenosine A1 receptor agonists and inhibitors of adenos-ine metabolism in a rat neuropathic pain model
    • Liu XJ, Sawynok J. Peripheral antihyperalgesic effects by adenosine A1 receptor agonists and inhibitors of adenos-ine metabolism in a rat neuropathic pain model. Analgesia 2000;5:19-29
    • (2000) Analgesia , vol.5 , pp. 19-29
    • Liu, X.J.1    Sawynok, J.2
  • 37
    • 0038689146 scopus 로고    scopus 로고
    • Adenosine in the spinal cord and periphery: Release and regulation of pain
    • Sawynok J, Liu XJ. Adenosine in the spinal cord and periphery: release and regulation of pain. Prog Neurobiol 2003;69:313-40
    • (2003) Prog Neurobiol , vol.69 , pp. 313-340
    • Sawynok, J.1    Liu, X.J.2
  • 38
    • 0035148239 scopus 로고    scopus 로고
    • Inhibition of infammation-induced thermal hypersen-sitivity by sumatriptan through activation of 5-HT (1B/1D) receptors
    • Bingham S, Davey PT, Sammons M, Raval P, Overend P, Parsons AA. Inhibition of infammation-induced thermal hypersen-sitivity by sumatriptan through activation of 5-HT (1B/1D) receptors. Exp Neurol 2001;167:65-73
    • (2001) Exp Neurol , vol.167 , pp. 65-73
    • Bingham, S.1    Davey, P.T.2    Sammons, M.3    Raval, P.4    Overend, P.5    Parsons, A.A.6
  • 40
    • 0025955808 scopus 로고
    • Dihydroergotamine and sumatriptan attenuate levels of CGRP in plasma in rat superior sagittal sinus during electrical stimulation of the trigeminal ganglion
    • Buzzi MG, Carter WB, Shimizu T, Heath H 3rd, Moskowitz MA. Dihydroergotamine and sumatriptan attenuate levels of CGRP in plasma in rat superior sagittal sinus during electrical stimulation of the trigeminal ganglion. Neuropharmacology 1991;30:1193-200
    • (1991) Neuropharmacology , vol.30 , pp. 1193-1200
    • Buzzi, M.G.1    Carter, W.B.2    Shimizu, T.3    Heath III, H.4    Moskowitz, M.A.5
  • 41
    • 0023137280 scopus 로고
    • GABAergic mechanisms of analgesia: An update
    • Sawynok J. GABAergic mechanisms of analgesia: an update. Pharmacol Biochem Behav 1987;26:463-74
    • (1987) Pharmacol Biochem Behav , vol.26 , pp. 463-474
    • Sawynok, J.1
  • 42
    • 0032788376 scopus 로고    scopus 로고
    • Peripheral GABA(A) receptors: Evidence for peripheral primary afferent depolarization
    • Carlton SM, Zhou S, Coggeshall RE. Peripheral GABA(A) receptors: evidence for peripheral primary afferent depolarization. Neuroscience 1999;93:713-22
    • (1999) Neuroscience , vol.93 , pp. 713-722
    • Carlton, S.M.1    Zhou, S.2    Coggeshall, R.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.