메뉴 건너뛰기




Volumn 1, Issue 3, 2012, Pages 263-270

Prevention of colitis-associated colon cancer using a vaccine to target abnormal expression of the MUC1 tumor antigen

Author keywords

Cancer vaccine; Colon cancer; Inflammation; Inflammatory bowel disease; MUC1

Indexed keywords

MUCIN 1;

EID: 84870242896     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.4161/onci.18950     Document Type: Article
Times cited : (24)

References (26)
  • 1
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens LM, Werb Z. Inflammation and cancer. Nature 2002; 420:860-7; http://dx.doi.org/10.1038/nature01322
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 2
    • 67650330166 scopus 로고    scopus 로고
    • Carcinogenesis in IBD: potential targets for the prevention of colorectal cancer
    • Feagins LA, Souza RF, Spechler SJ. Carcinogenesis in IBD: potential targets for the prevention of colorectal cancer. Nat Rev Gastroenterol Hepatol 2009; 6: 297-305; http://dx.doi.org/10.1038/nrgastro.2009.44
    • (2009) Nat Rev Gastroenterol Hepatol , vol.6 , pp. 297-305
    • Feagins, L.A.1    Souza, R.F.2    Spechler, S.J.3
  • 3
    • 79955564023 scopus 로고    scopus 로고
    • Intestinal inflammation and cancer
    • Ullman TA, Itzkowitz SH. Intestinal inflammation and cancer. Gastroenterology 2011; 140:1807-16; http://dx.doi.org/10.1053/j.gastro.2011.01.057
    • (2011) Gastroenterology , vol.140 , pp. 1807-1816
    • Ullman, T.A.1    Itzkowitz, S.H.2
  • 4
    • 79961167686 scopus 로고    scopus 로고
    • Importance of MUC1 and spontaneous mouse tumor models for understanding the immunobiology of human adenocarcinomas
    • Finn OJ, Gantt KR, Lepisto AJ, Pejawar-Gaddy S, Xue J, Beatty PL. Importance of MUC1 and spontaneous mouse tumor models for understanding the immunobiology of human adenocarcinomas. Immunol Res 2011; 50:261-8; http://dx.doi.org/10.1007/s12026-011-8214-1
    • (2011) Immunol Res , vol.50 , pp. 261-268
    • Finn, O.J.1    Gantt, K.R.2    Lepisto, A.J.3    Pejawar-Gaddy, S.4    Xue, J.5    Beatty, P.L.6
  • 5
    • 1142286444 scopus 로고    scopus 로고
    • MUC1 immunobiology: from discovery to clinical applications
    • Vlad AM, Kettel JC, Alajez NM, Carlos CA, Finn OJ. MUC1 immunobiology: from discovery to clinical applications. Adv Immunol 2004; 82:249-93; http://dx.doi.org/10.1016/S0065-2776(04)82006-6
    • (2004) Adv Immunol , vol.82 , pp. 249-293
    • Vlad, A.M.1    Kettel, J.C.2    Alajez, N.M.3    Carlos, C.A.4    Finn, O.J.5
  • 6
    • 18644383374 scopus 로고    scopus 로고
    • The dichotomy in the preinvasive neoplasia to invasive carcinoma sequence in the pancreas: differential expression of MUC1 andMUC2 supports the existence of two separate pathways of carcinogenesis
    • Adsay NV, Merati K, Andea A, Sarkar F, Hruban RH, Wilentz RE, et al. The dichotomy in the preinvasive neoplasia to invasive carcinoma sequence in the pancreas: differential expression of MUC1 andMUC2 supports the existence of two separate pathways of carcinogenesis. Mod Pathol 2002; 15:1087-95; http://dx.doi.org/10.1097/01.MP.0000028647.98725.8B
    • (2002) Mod Pathol , vol.15 , pp. 1087-1095
    • Adsay, N.V.1    Merati, K.2    Andea, A.3    Sarkar, F.4    Hruban, R.H.5    Wilentz, R.E.6
  • 7
    • 0030015828 scopus 로고    scopus 로고
    • Significance of MUC1 and MUC2 mucin expression in colorectal cancer
    • Ajioka Y, Allison LJ, Jass JR. Significance of MUC1 and MUC2 mucin expression in colorectal cancer. J Clin Pathol 1996; 49:560-4; http://dx.doi.org/10.1136/jcp.49.7.560
    • (1996) J Clin Pathol , vol.49 , pp. 560-564
    • Ajioka, Y.1    Allison, L.J.2    Jass, J.R.3
  • 8
    • 77950845966 scopus 로고    scopus 로고
    • Vaccine against MUC1 antigen expressed in inflammatory bowel disease and cancer lessens colonic inflammation and prevents progression to colitis-associated colon cancer
    • Beatty PL, Narayanan S, Gariepy J, Ranganathan S, Finn OJ. Vaccine against MUC1 antigen expressed in inflammatory bowel disease and cancer lessens colonic inflammation and prevents progression to colitis-associated colon cancer. Cancer Prev Res (Phila); 3:438-46.
    • Cancer Prev Res (Phila) , vol.3 , pp. 438-446
    • Beatty, P.L.1    Narayanan, S.2    Gariepy, J.3    Ranganathan, S.4    Finn, O.J.5
  • 9
    • 34548759771 scopus 로고    scopus 로고
    • Cutting edge: transgenic expression of human MUC1 in IL-102/2 mice accelerates inflammatory bowel disease and progression to colon cancer
    • Beatty PL, Plevy SE, Sepulveda AR, Finn OJ. Cutting edge: transgenic expression of human MUC1 in IL-102/2 mice accelerates inflammatory bowel disease and progression to colon cancer. J Immunol 2007; 179:735-9
    • (2007) J Immunol , vol.179 , pp. 735-739
    • Beatty, P.L.1    Plevy, S.E.2    Sepulveda, A.R.3    Finn, O.J.4
  • 10
    • 0029965197 scopus 로고    scopus 로고
    • Altered mucin core peptide immunoreactivity in the colon polyp-carcinoma sequence
    • Ho SB, Ewing SL, Montgomery CK, Kim YS. Altered mucin core peptide immunoreactivity in the colon polyp-carcinoma sequence. Oncol Res 1996; 8:53-61
    • (1996) Oncol Res , vol.8 , pp. 53-61
    • Ho, S.B.1    Ewing, S.L.2    Montgomery, C.K.3    Kim, Y.S.4
  • 11
    • 0030615097 scopus 로고    scopus 로고
    • A survivor of breast cancer with immunity toMUC-1 mucin, and lactational mastitis
    • Jerome KR, Kirk AD, Pecher G, Ferguson WW, Finn OJ. A survivor of breast cancer with immunity toMUC-1 mucin, and lactational mastitis. Cancer Immunol Immunother 1997; 43:355-60; http://dx.doi.org/10.1007/s002620050344
    • (1997) Cancer Immunol Immunother , vol.43 , pp. 355-360
    • Jerome, K.R.1    Kirk, A.D.2    Pecher, G.3    Ferguson, W.W.4    Finn, O.J.5
  • 12
    • 77951751295 scopus 로고    scopus 로고
    • Inflammation driven by overexpression of the hypoglycosylated abnormal mucin 1 (MUC1) links inflammatory bowel disease and pancreatitis
    • Kadayakkara DK, Beatty PL, Turner MS, Janjic JM, Ahrens ET, Finn OJ. Inflammation driven by overexpression of the hypoglycosylated abnormal mucin 1 (MUC1) links inflammatory bowel disease and pancreatitis. Pancreas 2010; 39:510-5; http://dx.doi.org/10.1097/MPA.0b013e3181bd6501
    • (2010) Pancreas , vol.39 , pp. 510-515
    • Kadayakkara, D.K.1    Beatty, P.L.2    Turner, M.S.3    Janjic, J.M.4    Ahrens, E.T.5    Finn, O.J.6
  • 13
    • 33751250222 scopus 로고    scopus 로고
    • Alterations in the composition of the supramucosal defense barrier in relation to disease severity of ulcerative colitis
    • Longman RJ, Poulsom R, Corfield AP, Warren BF, Wright NA, Thomas MG. Alterations in the composition of the supramucosal defense barrier in relation to disease severity of ulcerative colitis. J Histochem Cytochem 2006; 54:1335-48; http://dx.doi.org/10.1369/jhc.5A6904.2006
    • (2006) J Histochem Cytochem , vol.54 , pp. 1335-1348
    • Longman, R.J.1    Poulsom, R.2    Corfield, A.P.3    Warren, B.F.4    Wright, N.A.5    Thomas, M.G.6
  • 15
    • 35349002727 scopus 로고    scopus 로고
    • E6020: a synthetic Toll-like receptor 4 agonist as a vaccine adjuvant
    • Ishizaka ST, Hawkins LD. E6020: a synthetic Toll-like receptor 4 agonist as a vaccine adjuvant. Expert Rev Vaccines 2007; 6:773-84; http://dx.doi.org/10.1586/14760584.6.5.773
    • (2007) Expert Rev Vaccines , vol.6 , pp. 773-784
    • Ishizaka, S.T.1    Hawkins, L.D.2
  • 16
    • 0344844495 scopus 로고    scopus 로고
    • Nuclear magnetic resonance-based dissection of a glycosyltransferase specificity for the mucin MUC1 tandem repeat
    • Brokx RD, Revers L, Zhang Q, Yang S, Mal TK, Ikura M, et al. Nuclear magnetic resonance-based dissection of a glycosyltransferase specificity for the mucin MUC1 tandem repeat. Biochemistry 2003; 42:13817-25; http://dx.doi.org/10.1021/bi0353070
    • (2003) Biochemistry , vol.42 , pp. 13817-13825
    • Brokx, R.D.1    Revers, L.2    Zhang, Q.3    Yang, S.4    Mal, T.K.5    Ikura, M.6
  • 18
    • 33745177351 scopus 로고    scopus 로고
    • Regulation of mucin expression: mechanistic aspects and implications for cancer and inflammatory diseases
    • Andrianifahanana M, Moniaux N, Batra SK. Regulation of mucin expression: mechanistic aspects and implications for cancer and inflammatory diseases. Biochim Biophys Acta2006; 1765:189-222.
    • (2006) Biochim Biophys Acta , vol.1765 , pp. 189-222
    • Andrianifahanana, M.1    Moniaux, N.2    Batra, S.K.3
  • 19
    • 0031723707 scopus 로고    scopus 로고
    • Interaction of glycogen synthase kinase 3beta with the DF3/MUC1 carcinoma-associated antigen and beta-catenin
    • Li Y, Bharti A, Chen D, Gong J, Kufe D. Interaction of glycogen synthase kinase 3beta with the DF3/MUC1 carcinoma-associated antigen and beta-catenin. Mol Cell Biol 1998; 18:7216-24
    • (1998) Mol Cell Biol , vol.18 , pp. 7216-7224
    • Li, Y.1    Bharti, A.2    Chen, D.3    Gong, J.4    Kufe, D.5
  • 20
    • 0029160043 scopus 로고
    • Association of the DF3/MUC1 breast cancer antigen with Grb2 and the Sos/Ras exchange protein
    • Pandey P, Kharbanda S, Kufe D. Association of the DF3/MUC1 breast cancer antigen with Grb2 and the Sos/Ras exchange protein. Cancer Res 1995; 55:4000-3
    • (1995) Cancer Res , vol.55 , pp. 4000-4003
    • Pandey, P.1    Kharbanda, S.2    Kufe, D.3
  • 21
    • 10744220453 scopus 로고    scopus 로고
    • Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents
    • Ren J, Agata N, Chen D, Li Y, Yu WH, Huang L, et al. Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents. Cancer Cell 2004; 5:163-75; http://dx.doi.org/10.1016/S1535-6108(04)00020-0
    • (2004) Cancer Cell , vol.5 , pp. 163-175
    • Ren, J.1    Agata, N.2    Chen, D.3    Li, Y.4    Yu, W.H.5    Huang, L.6
  • 22
    • 7944230166 scopus 로고    scopus 로고
    • MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress
    • Yin L, Huang L, Kufe D. MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress. J Biol Chem 2004; 279:45721-7; http://dx.doi.org/10.1074/jbc.M408027200
    • (2004) J Biol Chem , vol.279 , pp. 45721-45727
    • Yin, L.1    Huang, L.2    Kufe, D.3
  • 23
    • 0035794196 scopus 로고    scopus 로고
    • A stat-responsive element in the promoter of the episialin/MUC1 gene is involved in its overexpression in carcinoma cells
    • Gaemers IC, Vos HL, Volders HH, van der Valk SW, Hilkens J. A stat-responsive element in the promoter of the episialin/MUC1 gene is involved in its overexpression in carcinoma cells. J Biol Chem 2001; 276: 6191-9; http://dx.doi.org/10.1074/jbc.M009449200
    • (2001) J Biol Chem , vol.276 , pp. 6191-6199
    • Gaemers, I.C.1    Vos, H.L.2    Volders, H.H.3    van der Valk, S.W.4    Hilkens, J.5
  • 24
    • 0037951722 scopus 로고    scopus 로고
    • Tumor necrosis factor increases MUC1 mRNA in cultured human nasal epithelial cells
    • Shirasaki H, Kanaizumi E, Watanabe K, Konno N, Sato J, Narita S, et al. Tumor necrosis factor increases MUC1 mRNA in cultured human nasal epithelial cells. Acta Otolaryngol 2003; 123:524-31; http://dx.doi.org/10.1080/00016480310001268
    • (2003) Acta Otolaryngol , vol.123 , pp. 524-531
    • Shirasaki, H.1    Kanaizumi, E.2    Watanabe, K.3    Konno, N.4    Sato, J.5    Narita, S.6
  • 25
    • 22544457164 scopus 로고    scopus 로고
    • Human tumor antigen MUC1 is chemotactic for immature dendritic cells and elicits maturation but does not promote Th1 type immunity
    • Carlos CA, Dong HF, Howard OM, Oppenheim JJ, Hanisch FG, Finn OJ. Human tumor antigen MUC1 is chemotactic for immature dendritic cells and elicits maturation but does not promote Th1 type immunity. J Immunol 2005; 175:1628-35
    • (2005) J Immunol , vol.175 , pp. 1628-1635
    • Carlos, C.A.1    Dong, H.F.2    Howard, O.M.3    Oppenheim, J.J.4    Hanisch, F.G.5    Finn, O.J.6
  • 26
    • 82755195700 scopus 로고    scopus 로고
    • MUC1 expression in tumor cells regulates transcription of proinflammatory cytokines by forming a complex with NF-{kappa}B p65 and binding to cytokine promoters: importance of the extracellular domain
    • Cascio S, Zhang L, Finn OJ. MUC1 expression in tumor cells regulates transcription of proinflammatory cytokines by forming a complex with NF-{kappa}B p65 and binding to cytokine promoters: importance of the extracellular domain. J Biol Chem 2011; 286:42248-56; http://dx.doi.org/10.1074/jbc.M111.297630
    • (2011) J Biol Chem , vol.286 , pp. 42248-42256
    • Cascio, S.1    Zhang, L.2    Finn, O.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.