The effects of α-lipoic acid against testicular ischemia-reperfusion injury in rats

The Scientific World Journal

Volumn 2012, Issue , 2012, Pages

  Ozbal, Seda ^a   Ergur, Bekir Ugur ^a   Erbil, G ^a   Tekmen, I ^a   Bagryank, A ^a   Cavdar, Z ^a  

^a DOKUZ EYLUL UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE PEROXIDASE; SUPEROXIDE DISMUTASE; THIOCTIC ACID; ANTIOXIDANT; CASPASE 3; MALONALDEHYDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DAMAGE; CONTROLLED STUDY; ENZYME ACTIVITY; GERM CELL; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; ISCHEMIA; MALE; NONHUMAN; RAT; REPERFUSION INJURY; SEMINIFEROUS TUBULE; SPERMATOGENESIS; TESTIS CELL; TESTIS TORSION; ANIMAL; DRUG EFFECT; METABOLISM; NICK END LABELING; OXIDATIVE STRESS; TESTIS DISEASE;

RATTUS;

ANIMALS; ANTIOXIDANTS; CASPASE 3; IN SITU NICK-END LABELING; MALE; MALONDIALDEHYDE; OXIDATIVE STRESS; RATS; REPERFUSION INJURY; SPERMATIC CORD TORSION; TESTICULAR DISEASES; THIOCTIC ACID;

EID: 84870223619     PISSN: 1537744X     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1100/2012/489248     Document Type: Article

References (33)

1. Pentyala S., Lee J., Yalamanchili P., Vitkun S., Khan S. A., Testicular torsion: a review. Journal of Lower Genital Tract Disease 2001 5 1 38 47 2-s2.0-0035113358 10.1046/j.1526-0976.2001.51008.x (Pubitemid 32170806)
2. Cuckow P. M., Frank J. D., Torsion of the testis. British Journal of Urology International 2000 86 3 349 353 2-s2.0-0033867491 10.1046/j.1464-410X. 2000.00106.x (Pubitemid 30621244)
3. Bartsch G., Frank St., Marberger H., Mikuz G., Testicular torsion: late results with special regard to fertility and endocrine function. Journal of Urology 1980 124 3 375 378 2-s2.0-0018947817 (Pubitemid 10004777)
4. Melekos M. D., Asbach H. W., Markou S. A., Etiology of acute scrotum in 100 boys with regard to age distribution. Journal of Urology 1988 139 5 1023 1025 2-s2.0-0023902772
5. Filho D. W., Torres M. A., Bordin A. L. B., Crezcynski-Pasa T. B., Boveris A., Spermatic cord torsion, reactive oxygen and nitrogen species and ischemia-reperfusion injury. Molecular Aspects of Medicine 2004 25 1-2 199 210 2-s2.0-1642422730 10.1016/j.mam.2004.02.020 (Pubitemid 38401942)
6. Moon C., Ahn M., Kim S., Yasuzumi F., Shin T., Increased expression of both constitutive and inducible forms of nitric oxide synthase in the delayed phase of acute experimental testicular torsion. Journal of Veterinary Medical Science 2005 67 4 453 456 2-s2.0-20344402326 10.1292/jvms.67.453 (Pubitemid 41380417)
7. Cuzzocrea S., Riley D. P., Caputi A. P., Salvemini D., Antioxidant therapy: a new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury. Pharmacological Reviews 2001 53 1 135 159 2-s2.0-0035101472 (Pubitemid 32173112)
8. Ozkurkcugil C., Yardimoglu M., Dalcik H., Erdogan S., Gokalp A., Effect of insulin-like growth factor-1 on apoptosis of rat testicular germ cells induced by testicular torsion. British Journal of Urology International 2004 93 7 1094 1097 2-s2.0-2542604544 10.1111/j.1464-410X.2004.04787.x (Pubitemid 38758640)
9. Ergur B. U., Kiray M., Pekcetin C., Bagriyanik H. A., Erbil G., Protective effect of erythropoietin pretreatment in testicular ischemia-reperfusion injury in rats. Journal of Pediatric Surgery 2008 43 4 722 728 2-s2.0-41549125831 10.1016/j.jpedsurg.2007.11.028 (Pubitemid 351474531)
10. Kanter M., Protective effects of melatonin on testicular torsion/detorsion-induced ischemia-reperfusion injury in rats. Experimental and Molecular Pathology 2010 89 3 314 320 2-s2.0-78249262577 10.1016/j.yexmp.2010. 07.006
11. Wong A., Dukic-Stefanovic S., Gasic-Milenkovic J., Schinzel R., Wiesinger H., Riederer P., Münch G., Anti-inflammatory antioxidants attenuate the expression of inducible nitric oxide synthase mediated by advanced glycation endproducts in murine microglia. European Journal of Neuroscience 2001 14 12 1961 1967 2-s2.0-0035783744 10.1046/j.0953-816X.2001.01820.x (Pubitemid 35463683)
12. Shay K. P., Moreau R. F., Smith E. J., Smith A. R., Hagen T. M., Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochimica et Biophysica Acta 2009 1790 10 1149 1160 2-s2.0-69949104384 10.1016/j.bbagen.2009.07.026
13. Shay K. P., Moreau R. F., Smith E. J., Hagen T. M., Is α -lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity. IUBMB Life 2008 60 6 362 367 2-s2.0-48849114553 10.1002/iub.40
14. Biewenga G. P., Haenen G. R. M. M., Bast A., The pharmacology of the antioxidant: lipoic acid. General Pharmacology 1997 29 3 315 331 2-s2.0-0030768236 10.1016/S0306-3623(96)00474-0 (Pubitemid 27412452)
15. Goraca A., Huk-Kolega H., Piechota1 A., Kleniewska1 P., Ciejka E., Skibska B., Lipoic acid-biological activity and therapeutic Potential. Pharmacological Reports 2011 63 4 849 858
16. Connell B. J., Saleh M., Khan B. V., Saleh T. M., Lipoic acid protects against reperfusion injury in the early stages of cerebral ischemia. Brain Research C 2011 1375 128 136 2-s2.0-79651475501 10.1016/j.brainres.2010.12.045
17. Radu F., Leggett R. E., Schuler C., Levin R. M., The effect of antioxidants on the response of the rabbit urinary bladder to in vitro ischemia/reperfusion. Molecular and Cellular Biochemistry 2011 1 9 2-s2.0-79955393939 10.1007/s11010-011-0839-9
18. Wang X., Yu Y., Ji L., Liang X., Zhang T., Hai C. X., Alpha-lipoic acid protects against myocardial ischemia/reperfusion injury via multiple target effects. Food and Chemical Toxicology 2011 49 11 2750 2757 10.1016/j.fct.2011. 07.065
19. Tunc T., Öter S., Güven A., Topal T., Kul M., Korkmaz A., Öngürü Ö., Sarici Ü., Protective effect of sulfhydryl-containing antioxidants against ischemia/reperfusion injury of prepubertal rat intestine. Journal of Gastroenterology and Hepatology 2009 24 4 681 687 2-s2.0-63849131592 10.1111/j.1440-1746.2008.05673.x
20. Shaafi S., Afrooz M. R., Hajipour B., Dadadshi A., Hosseinian M. M., Khodadadi A., Anti-oxidative effect of lipoic acid in spinal cord ischemia/reperfusion. Medical Principles and Practice 2010 20 1 19 22 2-s2.0-78650457314 10.1159/000319772
21. Tatum V. L., Changchit C., Chow C. K., Measurement of malondialdehyde by high performance liquid chromatography with fluorescence detection. Lipids 1990 25 4 226 229 2-s2.0-0025259264 (Pubitemid 20135055)
22. Wiechelman K. J., Braun R. D., Fitzpatrick J. D., Investigation of the bicinchoninic acid protein assay: identification of the groups responsible for color formation. Analytical Biochemistry 1988 175 1 231 237 2-s2.0-0024289285
23. Johnsen S. G., Testicular biopsy score count-a method for registration of spermatogenesis in human testes: normal values and results in 335 hypogonadal males. Hormones 1970 1 1 2 25 2-s2.0-0014893015
24. Dokmeci D., Inan M., Basaran U. N., Yalcin O., Aydogdu N., Turan F. N., Uz Y. H., Protective effect of L-carnitine on testicular ischaemia-reperfusion injury in rats. Cell Biochemistry and Function 2007 25 6 611 618 2-s2.0-33947696375 10.1002/cbf.1355 (Pubitemid 351202346)
25. Kehinde E. O., Anim J. T., Mojiminiyi O. A., Al-Awadi F., Shihab-Eldeen A., Omu A. E., Fatinikun T., Prasad A., Abraham M., Allopurinol provides long-term protection for experimentally induced testicular torsion in a rabbit model. British Journal of Urology International 2005 96 1 175 180 2-s2.0-21744441531 10.1111/j.1464-410X.2005.05590.x (Pubitemid 40942892)
26. Romeo C., Antonuccio P., Esposito M., Marini H., Impellizzeri P., Turiaco N., Altavilla D., Bitto A., Zuccarello B., Squadrito F., Raxofelast, a hydrophilic vitamin e-like antioxidant, reduces testicular ischemia-reperfusion injury. Urological Research 2004 32 5 367 371 2-s2.0-8744293495 10.1007/s00240-004-0436-4 (Pubitemid 39517962)
27. Tunçkiran A., Çayan S., Bozlu M., Yilmaz N., Acar D., Akbay E., Protective effect of vascular endothelial growth factor on histologic changes in testicular ischemia-reperfusion injury. Fertility and Sterility 2005 84 2 468 473 2-s2.0-23744487029 10.1016/j.fertnstert.2005.01.144 (Pubitemid 41125272)
28. Cay A., Alver A., Küçük M., Işik O., Eminaaolu M. S., Karahan S. C., Deer O., The effects of N-acetylcysteine on antioxidant enzyme activities in experimental testicular torsion. Journal of Surgical Research 2006 131 2 199 203 2-s2.0-33644900721 10.1016/j.jss.2005.11.572
29. Li C. J., Zhang Q. M., Li M. Z., Zhang J. Y., Yu P., Yu D. M., Attenuation of myocardial apoptosis by alpha-lipoic acid through suppression of mitochondrial oxidative stress to reduce diabetic cardiomyopathy. Chinese Medical Journal 2009 122 21 2580 2586 2-s2.0-73449142511 10.3760/cma.j.issn. 0366-6999.2009.21.010
30. Dadhania V. P., Tripathi D. N., Vikram A., Ramarao P., Jena G. B., Intervention of α -lipoic acid ameliorates methotrexate-induced oxidative stress and genotoxicity: a study in rat intestine. Chemico-Biological Interactions 2010 183 1 85 97 2-s2.0-71549114179 10.1016/j.cbi.2009.10.020
31. Bae E. H., Lee J., Ma S. K., Kim I. J., Frokiær J., Nielsen S., Kim S. Y., Kim S. W., α -Lipoic acid prevents cisplatin-induced acute kidney injury in rats. Nephrology Dialysis Transplantation 2009 24 9 2692 2700 2-s2.0-69249104119 10.1093/ndt/gfp176
32. Antonio A. M., Gillespie R. A., Druse-Manteuffel M. J., Effects of lipoic acid on antiapoptotic genes in control and ethanol-treated fetal rhombencephalic neurons. Brain Research 2011 1383 13 21 2-s2.0-79952984884 10.1016/j.brainres.2011.01.113
33. Guimarães S. B., Santos J. M. V., Aragão A. A., de Sandes Kimura O., Barbosa P. H. U., de Vasconcelos P. R. L., Protective effect of α -lipoic acid in experimental spermatic cord torsion. Nutrition 2007 23 1 76 80 2-s2.0-33845656381 10.1016/j.nut.2006.09.005 (Pubitemid 44959763)