Patterns of gray and white matter changes in individuals at risk for Alzheimer's disease

Current Alzheimer Research

Volumn 9, Issue 9, 2012, Pages 1097-1105

  Jacobs, Heidi I L ^a,b,c   van Boxtel, Martin P J ^a,b   Gronenschild, H B M ^a,b   Williams, Victoria J ^d   Burgmans, Saartje ^a,b   Uylings, Harry B M ^a,b,e   Jolles, Jelle ^a,b,f   Verhey, Frans R J ^a,b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b European Graduate School of Neuroscience   (Netherlands)

^c FORSCHUNGSZENTRUM JÜLICH   (Germany)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^f VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Cortical thickness; Diffusion tensor imaging; Early detection; Magnetic resonance imaging; Memory decline; Preclinical alzheimer's disease

Indexed keywords

ADULT; AGED; ALZHEIMER DISEASE; AMNESIA; ARTICLE; CLINICAL ARTICLE; COGNITION; CORONA RADIATA (BRAIN); CORPUS CALLOSUM; CORPUS STRIATUM; DIFFUSION TENSOR IMAGING; FEMALE; GRAY MATTER; HIPPOCAMPUS; HUMAN; INFERIOR PARIETAL LOBULE; LEARNING; LONGITUDINAL STUDY; MALE; MENTAL PERFORMANCE; MIDDLE FRONTAL GYRUS; MIDDLE TEMPORAL GYRUS; NERVE TRACT; NUCLEAR MAGNETIC RESONANCE IMAGING; OCCIPITAL LOBE; PARAHIPPOCAMPAL GYRUS; PARIETAL LOBE; PARS OPERCULARIS; POSTCENTRAL GYRUS; POSTERIOR CINGULATE; PRECENTRAL SULCUS; PRECUNEUS; PRIORITY JOURNAL; RISK; SUPERIOR FRONTAL GYRUS; SUPERIOR LONGITUDINAL BUNDLE; SUPERIOR PARIETAL LOBULE; SUPRAMARGINAL GYRUS; TASK PERFORMANCE; TEMPORAL LOBE; WHITE MATTER;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; BRAIN; COGNITION DISORDERS; EARLY DIAGNOSIS; FEMALE; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; RISK FACTORS;

EID: 84870221348     PISSN: 15672050     EISSN: 18755828     Source Type: Journal    
DOI: 10.2174/156720512803568993     Document Type: Article

References (65)

1. Wilson RS, Leurgans SE, Boyle PA, Bennett DA. Cognitive decline in prodromal Alzheimer disease and mild cognitive impairment. Arch Neurol 68: 351-356 (2011).
2. Baars MA, van Boxtel MP, Dijkstra JB, Visser PJ, van den Akker M, Verhey FR, et al. Predictive value of mild cognitive impairment for dementia. The influence of case definition and age. Dementia and geriatric cognitive disorders 27: 173-181 (2009).
3. Dubois B, Feldman HH, Jacova C, Cummings JL, Dekosky ST, Barberger-Gateau P, et al. Revising the definition of Alzheimer's disease: a new lexicon. Lancet Neurol 9: 1118-1127 (2010).
4. Jack CR, Jr., Knopman DS, Jagust WJ, Shaw LM, Aisen PS, Weiner MW, et al. Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade. Lancet Neurol 9: 119-228 (2010).
5. Saykin AJ, Wishart HA, Rabin LA, Santulli RB, Flashman LA, West JD, et al. Older adults with cognitive complaints show brain atrophy similar to that of amnestic MCI. Neurology 67: 834-842 (2006).
6. Smith CD, Chebrolu H, Wekstein DR, Schmitt FA, Jicha GA, Cooper G, et al. Brain structural alterations before mild cognitive impairment. Neurology 68: 1268-1273 (2007).
7. Singh V, Chertkow H, Lerch JP, Evans AC, Dorr AE, Kabani NJ, et al. Spatial patterns of cortical thinning in mild cognitive impairment and Alzheimer's disease. Brain 129: 2885-2893 (2006).
8. Scahill RI, Schott JM, Stevens JM, Rossor MN, Fox NC. Mapping the evolution of regional atrophy in Alzheimer's disease: unbiased analysis of fluid-registered serial MRI. Proc Natl Acad Sci USA 99: 4703-4707 (2002).
9. Desikan RS, Cabral HJ, Fischl B, Guttmann CR, Blacker D, Hyman BT, et al. Temporoparietal MR imaging measures of atrophy in subjects with mild cognitive impairment that predict subsequent diagnosis of Alzheimer disease. AJNR Am J Neuroradiol 30: 532-538 (2009).
10. Cho H, Yang DW, Shon YM, Kim BS, Kim YI, Choi YB, et al. Abnormal integrity of corticocortical tracts in mild cognitive impairment: a diffusion tensor imaging study. Journal of Korean medical science 23: 477-483 (2008).
11. Medina D, DeToledo-Morrell L, Urresta F, Gabrieli JD, Moseley M, Fleischman D, et al. White matter changes in mild cognitive impairment and AD: A diffusion tensor imaging study. Neurobiol Aging 27: 663-672 (2006).
12. Salat DH, Tuch DS, van der Kouwe AJ, Greve DN, Pappu V, Lee SY, et al. White matter pathology isolates the hippocampal formation in Alzheimer's disease. Neurobiol Aging 31: 244-256 (2010).
13. Van Boxtel MPJ, Buntinx F, Houx PJ, Metsemakers JF, Knottnerus A, Jolles J, et al. The relation between morbidity and cognitive performance in a normal aging population. J Gerontol A Biol Sci Med Sci 53: M147-M154 (1998).
14. Folstein MF, Folstein, S.E., & McHugh, P.R. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatric Res 12: 189-198 (1975).
15. Van der Elst W, van Boxtel MPJ, van Breukelen GJP, Jolles J. Rey's verbal learning test: normative data for 1855 healthy participants aged 24-81 years and the influence of age, sex, education, and mode of presentation. J Int Neuropsychol Soc 11: 290-302 (2005).
16. Rey A. L'examen clinique en psychologie. Paris: Presses Universitaires de France 1694.
17. Rabin LA, Pare N, Saykin AJ, Brown MJ, Wishart HA, Flashman LA, et al. Differential memory test sensitivity for diagnosing amnestic mild cognitive impairment and predicting conversion to Alzheimer's disease. Neuropsychol Dev Cogn 16: 357-376 (2009).
18. DeBie SE. Standaardvragen 1987: Voorstellen voor uniformering van vraagstellingen naar achtergrondkenmerken en interviews [1987 Standardized questions: Proposal for uniform questions on background variables and interviews]. Leiden, The Netherlands: Leiden University Press 1987.
19. Burgmans S, van Boxtel MP, van den Berg KE, Brown MJ, Wishart HA, Flashman LA, et al. The posterior parahippocampal gyrus is preferentially affected in age-related memory decline. Neurobiol Aging 32: 1572-1578 (2009).
20. Smith SM. Fast robust automated brain extraction. Hum Brain Mapp 17: 143-155 (2002).
21. Roebroeck A, Galuske R, Formisano E, Chiry O, Bratzke H, Ronen I, et al. High-resolution diffusion tensor imaging and tractography of the human optic chiasm at 9.4 T. Neuroimage 39: 157-168 (2008).
22. Westin CF, Maier SE, Mamata H, Nabavi A, Jolesz FA, Kikinis R. Processing and visualization for diffusion tensor MRI. Med Image Anal 6: 93-108 (2002).
23. Burgmans S, van Boxtel MP, Gronenschild EH, Vuurman EF, Hofman P, Uylings HB, et al. Multiple indicators of agerelated differences in cerebral white matter and the modifying effects of hypertension. Neuroimage 49: 2083-2093 (2009).
24. Smith SM, Jenkinson M, Johansen-Berg H, Rueckert D, Nichols TE, Mackay CE, et al. Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data. Neuroimage 31: 1487-1505 (2006).
25. Rosas HD, Liu AK, Hersch S, Glessner M, Ferrante RJ, Salat DH, et al. Regional and progressive thinning of the cortical ribbon in Huntington's disease. Neurology 58: 695-701 (2002).
26. Kuperberg GR, Broome MR, McGuire PK, David AS, Eddy M, Ozawa F, et al. Regionally localized thinning of the cerebral cortex in schizophrenia. Arch Gen Psychiatry 60: 878-888 (2003).
27. Han X, Jovicich J, Salat D, van der Kouwe A, Quinn B, Czanner S, et al. Reliability of MRI-derived measurements of human cerebral cortical thickness: the effects of field strength, scanner upgrade and manufacturer. Neuroimage 32: 180-194 (2006).
28. Dale AM, Fischl B, Sereno MI. Cortical surface-based analysis. I. Segmentation and surface reconstruction. Neuroimage 9: 179-194 (1999).
29. Fischl B, Liu A, Dale AM. Automated manifold surgery: constructing geometrically accurate and topologically correct models of the human cerebral cortex. IEEE Trans Med Imaging 20: 70-80 (2001).
30. Fischl B, Sereno MI, Dale AM. Cortical surface-based analysis. II: Inflation, flattening, and a surface-based coordinate system. Neuroimage 9: 195-207 (1999).
31. Fischl B, Sereno MI, Tootell RB, Dale AM. High-resolution intersubject averaging and a coordinate system for the cortical surface. Hum Brain Mapp 8: 272-284 (1999).
32. Sled JG, Zijdenbos AP, Evans AC. A nonparametric method for automatic correction of intensity nonuniformity in MRI data. IEEE Trans Med Imaging 17: 87-97 (1998).
33. Desikan RS, Segonne F, Fischl B, Quinn BT, Dickerson BC, Blacker D, et al. An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. Neuroimage 31: 968-980 (2006).
34. Dickerson BC, Bakkour A, Salat DH, Feczko E, Pacheco J, Greve DN, et al. The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloidpositive individuals. Cereb Cortex 19: 497-510 (2009).
35. Chumbley JR, Friston KJ. False discovery rate revisited: FDR and topological inference using Gaussian random fields. Neuroimage 44: 62-70 (2009).
36. Buckner RL, Wheeler ME. The cognitive neuroscience of remembering. Nat Rev Neurosci 2: 624-634 (2001).
37. Rose SE, Janke AL, Chalk JB. Gray and white matter changes in Alzheimer's disease: a diffusion tensor imaging study. J Magn Reson Imaging 27: 20-26 (2008).
38. Bell-McGinty S, Lopez OL, Meltzer CC, Scanlon JM, Whyte EM, Dekosky ST, et al. Differential cortical atrophy in subgroups of mild cognitive impairment. Arch Neurol 62: 1393-1397 (2005).
39. Burgmans S, van Boxtel MP, Smeets F, et al. Prefrontal cortex atrophy predicts dementia over a six-year period. Neurobiol Aging Sep 30: 1413-1419 (2009).
40. Desikan RS, Fischl B, Cabral HJ, Kemper TL, Guttmann CR, Blacker D, et al. MRI measures of temporoparietal regions show differential rates of atrophy during prodromal AD. Neurology 71: 819-825 (2008).
41. Karas GB, Sluimer J, Goekoop R, van der Flier W, Rombouts SA, Vrenken H, et al. Amnestic mild cognitive impairment: structural MR imaging findings predictive of conversion to Alzheimer disease. AJNR Am J Neuroradiol 29: 944-999 (2008).
42. Echavarri C, Aalten P, Uylings HB, Jacobs HI, Visser PJ, Gronenschild EH, et al. Atrophy in the parahippocampal gyrus as an early biomarker of Alzheimer's disease. Brain structure & function 215: 265-271 (2010).
43. Insausti R, Amaral DG, Cowan WM. The entorhinal cortex of the monkey: II. Cortical afferents. J Comp Neurol 264: 356-395 (1987).
44. Vann SD, Aggleton JP, Maguire EA. What does the retrosplenial cortex do? Nature reviews Neuroscience 10: 792-802 (2009).
45. Jacobs HIL, Van Boxtel MP, Uylings HB, et al. Atrophy of the parietal lobe in preclinical dementia. Brain Cogn 75: 154-163 (2011).
46. Jacobs HIL, Van Boxtel MPJ, Jolles J, Verhey FRJ, Uylings HBM. Parietal cortex matters in Alzheimer's disease: an overview of structural, functional and metabolic findings. Neurosci Biobehav Rev 36: 297-309 (2012).
47. Buckner RL, Snyder AZ, Shannon BJ, LaRossa G, Sachs R, Fotenos AF, et al. Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory. J Neurosci 25: 7709-7717 (2005).
48. Jacobs HIL, Van Boxtel MPJ, Heinecke A, Gronenschild EH, Backes WH, Ramakers IH, et al. Functional integration of parietal lobe activity in early Alzheimer's disease. Neurology: accepted (2012).
49. Villain N, Fouquet M, Baron JC, Mézenge F, Landeau B, de La Sayette V, et al. Sequential relationships between grey matter and white matter atrophy and brain metabolic abnormalities in early Alzheimer's disease. Brain 133: 3301-3314 (2010).
50. Song SK, Sun SW, Ju WK, Lin SJ, Cross AH, Neufeld AH, et al. Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia. Neuroimage 20: 1714-1722 (2003).
51. Bartzokis G, Lu PH, Mintz J. Human brain myelination and amyloid beta deposition in Alzheimer's disease. Alzheimers Dement 3: 122-125 (2007).
52. Salat DH, Kaye JA, Janowsky JS. Greater orbital prefrontal volume selectively predicts worse working memory performance in older adults. Cereb Cortex 12: 494-505 (2002).
53. Salat DH, Lee SY, van der Kouwe AJ, Greve DN, Fischl B, Rosas HD, et al. Age-associated alterations in cortical gray and white matter signal intensity and gray to white matter contrast. Neuroimage 48: 21-28 (2009).
54. Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales. Neuropathology Group of the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS). Lancet 357: 169-175 (2001).
55. Pfefferbaum A, Adalsteinsson E, Sullivan EV. Frontal circuitry degradation marks healthy adult aging: Evidence from diffusion tensor imaging. Neuroimage 26: 891-899 (2005).
56. Chua TC, Wen W, Slavin MJ, Sachdev PS. Diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease: a review. Current opinion in neurology 21: 83-92 (2008).
57. Bosch B, Arenaza-Urquijo EM, Rami L, Sala-Llonch R, Junqué C, Solé-Padullés C, et al. Multiple DTI index analysis in normal aging, amnestic MCI and AD. Relationship with neuropsychological performance. Neurobiol Aging doi:10.1016/j.neurobiolaging.2010.02.004: (2010).
58. Zhuang L, Wen W, Zhu W, Trollor J, Kochan N, Crawford J, et al. White matter integrity in mild cognitive impairment: a tract-based spatial statistics study. Neuroimage 53: 16-25 (2010).
59. Wheeler-Kingshott CA, Cercignani M. About "axial" and "radial" diffusivities. Magn Reson Med 61: 1255-1260 (2009).
60. Salat DH, Greve DN, Pacheco JL, Quinn BT, Helmer KG, Buckner RL, et al. Regional white matter volume differences in nondemented aging and Alzheimer's disease. Neuroimage 44: 1247-1258 (2009).
61. Huang J, Auchus AP. Diffusion tensor imaging of normal appearing white matter and its correlation with cognitive functioning in mild cognitive impairment and Alzheimer's disease. Ann NY Acad Sci 1097: 259-264 (2007).
62. Buckner RL, Andrews-Hanna JR, Schacter DL. The brain's default network: anatomy, function, and relevance to disease. Ann NY Acad Sci 1124: 1-38 (2008).
63. Zhang HY, Wang SJ, Xing J, Liu B, Ma ZL, Yang M, et al. Detection of PCC functional connectivity characteristics in restingstate fMRI in mild Alzheimer's disease. Behavioural brain Res 197: 103-108 (2009).
64. Madden DJ, Spaniol J, Costello MC, Bucur B, White LE, Cabeza R, et al. Cerebral white matter integrity mediates adult age differences in cognitive performance. J Cogn Neurosci 21: 289-302 (2009).
65. Petersen RC, Negash S. Mild cognitive impairment: an overview. CNS spectrums 13: 45-53 (2008).