Clinical course of occupational irritant contact dermatitis of the hands in relation to filaggrin genotype status and atopy

British Journal of Dermatology

Volumn 167, Issue 6, 2012, Pages 1302-1309

  Landeck, L ^a   Visser, M ^b   Skudlik, C ^a   Brans, R ^a   Kezic, S ^b   John, S M ^a  

^a UNIVERSITY OF OSNABRÜCK   (Germany)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; FILAGGRIN;

ADULT; AGED; ALLELE; ARTICLE; COHORT ANALYSIS; CORTICOSTEROID THERAPY; DISEASE COURSE; FEMALE; GENE MUTATION; GENOTYPE; HUMAN; IRRITANT DERMATITIS; MAJOR CLINICAL STUDY; MALE; OCCUPATIONAL ECZEMA; OCCUPATIONAL IRRITANT CONTACT DERMATITIS; PRIORITY JOURNAL; PROSPECTIVE STUDY;

ADOLESCENT; ADULT; AGED; COHORT STUDIES; DERMATITIS, IRRITANT; DERMATITIS, OCCUPATIONAL; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAND; HUMANS; INTERMEDIATE FILAMENT PROTEINS; MALE; MIDDLE AGED; MUTATION; POLYMORPHISM, GENETIC; PROSPECTIVE STUDIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

EID: 84870185788     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/bjd.12035     Document Type: Article

References (32)

1. Cahill J, Keegel T, Nixon R,. The prognosis of occupational contact dermatitis in 2004. Contact Dermatitis 2004; 51: 219-26.
2. Lee A, Nixon R,. Occupational skin disease in hairdressers. Australas J Dermatol 2001; 42: 1-6.
3. Brown SJ, McLean WH,. Eczema genetics: current state of knowledge and future goals. J Invest Dermatol 2009; 129: 543-52.
4. Brown SJ, Irvine AD,. Atopic eczema and the filaggrin story. Semin Cutan Med Surg 2008; 27: 128-37.
5. Irvine AD, McLean WH, Leung DY,. Filaggrin mutations associated with skin and allergic diseases. N Engl J Med 2011; 365: 1315-27.
6. Gibbs NK, Tye J, Norval M,. Recent advances in urocanic acid photochemistry, photobiology and photoimmunology. Photochem Photobiol Sci 2008; 7: 655-67.
7. de Jongh CM, Khrenova L, Verberk M, et al. Loss-of-function polymorphisms in the filaggrin gene increase susceptibility to chronic irritant contact dermatitis. Br J Dermatol 2008; 159: 621-7.
8. Kezic S, Kemperman PM, Koster ES, et al. Loss-of-function mutations in the filaggrin gene lead to reduced level of natural moisturizing factor in the stratum corneum. J Invest Dermatol 2008; 128: 2117-9.
9. Kezic S, O'Regan GM, Lutter R, et al. Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency. J Allergy Clin Immunol 2012; 129: 1031-9.
10. Presland RB, Boggess D, Lewis SP, et al. Loss of normal profilaggrin and filaggrin in flaky tail (ft/ft) mice: an animal model for the filaggrin-deficient skin disease ichthyosis vulgaris. J Invest Dermatol 2000; 115: 1072-81.
11. Scharschmidt TC, Man MQ, Hatano Y, et al. Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens. J Allergy Clin Immunol 2009; 124: 496-506.
12. Lindberg M, Matura M,. Patch testing. In: Textbook of Contact Dermatitis (, Johansen JD, Frosch PJ, Leppittevin JP, eds). Berlin: Springer, 2011; 439-64.
13. Uter W, Schwanitz HJ, Pfahlberg A, Gefeller O,. Atopic signs and symptoms: assessing the 'atopy score' concept. Dermatology 2001; 202: 4-8.
14. Diepgen TL, Sauerbrei W, Fartasch M,. Development and validation of diagnostic scores for atopic dermatitis incorporating criteria of data quality and practical usefulness. J Clin Epidemiol 1996; 49: 1031-8.
15. Skudlik C, Wulfhorst B, Gediga G, et al. Tertiary individual prevention of occupational skin diseases: a decade's experience with recalcitrant occupational dermatitis. Int Arch Occup Environ Health 2008; 81: 1059-64.
16. Skudlik C, Dulon M, Pohrt U, et al. Osnabrück hand eczema severity index-a study of the interobserver reliability of a scoring system assessing skin diseases of the hands. Contact Dermatitis 2006; 55: 42-7.
17. Palmer CN, Irvine AD, Terron-Kwiatkowski A, et al. Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis. Nat Genet 2006; 38: 441-6.
18. Thyssen JP, Ross-Hansen K, Johansen JD, et al. Filaggrin loss-of-function mutation R501X and 2282del4 carrier status is associated with fissured skin on the hands: results from a cross-sectional population study. Br J Dermatol 2012; 166: 46-53.
19. Brown SJ, McLean WH,. One remarkable molecule: filaggrin. J Invest Dermatol 2012; 132: 751-62.
20. Flohr C, England K, Radulovic S, et al. Filaggrin loss-of-function mutations are associated with early-onset eczema, eczema severity and transepidermal water loss at 3 months of age. Br J Dermatol 2010; 163: 1333-6.
21. Henderson J, Northstone K, Lee SP, et al. The burden of disease associated with filaggrin mutations: a population-based, longitudinal birth cohort study. J Allergy Clin Immunol 2008; 121: 872-7.
22. Brown SJ, Sandilands A, Zhao Y, et al. Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema. J Invest Dermatol 2008; 128: 1591-4.
23. Carlsen BC, Johansen JD, Menné T, et al. Filaggrin null mutations and association with contact allergy and allergic contact dermatitis: results from a tertiary dermatology clinic. Contact Dermatitis 2010; 63: 89-95.
24. Thyssen JP, Carlsen BC, Menné T, et al. Filaggrin null mutations increase the risk and persistence of hand eczema in subjects with atopic dermatitis: results from a general population study. Br J Dermatol 2010; 163: 115-20.
25. O'Regan GM, Irvine AD,. The role of filaggrin in the atopic diathesis. Clin Exp Allergy 2010; 40: 965-72.
26. Thyssen JP, Johansen JD, Linneberg A, Menné T,. The epidemiology of hand eczema in the general population-prevalence and main findings. Contact Dermatitis 2010; 62: 75-87.
27. Weidinger S, Rodríguez E, Stahl C, et al. Filaggrin mutations strongly predispose to early-onset and extrinsic atopic dermatitis. J Invest Dermatol 2007; 127: 724-6.
28. Greisenegger E, Novak N, Maintz L, et al. Analysis of four prevalent filaggrin mutations (R501X, 2282del4, R2447X and S3247X) in Austrian and German patients with atopic dermatitis. J Eur Acad Dermatol Venereol 2010; 24: 607-10.
29. Kawasaki H, Nagao K, Kubo A, et al. Altered stratum corneum barrier and enhanced percutaneous immune responses in filaggrin-null mice. J Allergy Clin Immunol 2012; 129: 1538-46.
30. Jungersted JM, Scheer H, Mempel M, et al. Stratum corneum lipids, skin barrier function and filaggrin mutations in patients with atopic eczema. Allergy 2010; 65: 911-8.
31. Hubiche T, Ged C, Benard A, et al. Analysis of SPINK 5, KLK 7 and FLG genotypes in a French atopic dermatitis cohort. Acta Derm Venereol 2007; 87: 499-505.
32. Jakasa I, Koster ES, Calkoen F, et al. Skin barrier function in healthy subjects and patients with atopic dermatitis in relation to filaggrin loss-of-function mutations. J Invest Dermatol 2011; 131: 540-2.