Acute toxicity of ferric oxide and zinc oxide nanoparticles in rats

Journal of Nanoscience and Nanotechnology

Volumn 10, Issue 12, 2010, Pages 8617-8624

  Wang, Lijuan ^a   Wang, Lin ^a   Ding, Wenjun ^a   Zhang, Fang ^a  

^a UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Acute toxicity; Nanoscale Fe 2O 3; Nanoscale ZnO; Rats

Indexed keywords

ACUTE TOXICITY; ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BIOCHEMICAL PARAMETERS; BODY WEIGHT; CONTENT OF FE; CREATINE KINASE; FERRIC OXIDE; HISTOPATHOLOGICAL EXAMINATIONS; INHALATION EXPOSURE; LACTATE DEHYDROGENASE; LIVER TISSUE; LUNG TISSUE; NANOSCALE FE 2O 3; NANOSCALE ZNO; POST-EXPOSURE; TOTAL PROTEIN; TOXIC EFFECT; WISTAR RAT; ZINC OXIDE NANOPARTICLES; ZNO; ZNO NANOPARTICLES;

ALKALINITY; AMINO ACIDS; ANTHROPOMETRY; BODY FLUIDS; ENZYMES; HISTOLOGY; IRON OXIDES; LIVER; NANOPARTICLES; NANOSTRUCTURED MATERIALS; PHOSPHATASES; RATS; TISSUE; TOXICITY; ZINC;

ZINC OXIDE;

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CREATINE KINASE; FERRIC ION; FERRIC OXIDE; LACTATE DEHYDROGENASE; METAL NANOPARTICLE; ZINC OXIDE;

ANALYSIS OF VARIANCE; ANIMAL; ARTICLE; ATOMIC FORCE MICROSCOPY; BLOOD; CHEMISTRY; CYTOCHEMISTRY; DRUG EFFECT; EXPOSURE; LIVER; LUNG; MALE; PATHOLOGY; RAT; TISSUE DISTRIBUTION; TOXICITY TESTING; WISTAR RAT; X RAY DIFFRACTION;

ACUTE TOXICITY TESTS; ALANINE TRANSAMINASE; ANALYSIS OF VARIANCE; ANIMALS; ASPARTATE AMINOTRANSFERASES; CREATINE KINASE; FERRIC COMPOUNDS; HISTOCYTOCHEMISTRY; INHALATION EXPOSURE; L-LACTATE DEHYDROGENASE; LIVER; LUNG; MALE; METAL NANOPARTICLES; MICROSCOPY, ATOMIC FORCE; RATS; RATS, WISTAR; TISSUE DISTRIBUTION; X-RAY DIFFRACTION; ZINC OXIDE;

EID: 79952109156     PISSN: 15334880     EISSN: None     Source Type: Journal    
DOI: 10.1166/jnn.2010.2483     Document Type: Conference Paper

References (42)

1. E. Bermudez, J. B. Mangum, B. A. Wong, B. Asgharian, P. M. Hext, D. B. Warheit, and J. I. Everitt, Toxicol. Sci. 77, 2 (2004).
2. E. Oberdorster, Environ. Health Perspect. 112, 10 (2004).
3. B. Wang, W. Feng, M. Zhu, Y. Wang, M. Wang, Y. Gu, H. Ouyang, H. Wang, M. Li, Y. Zhao, Z. Chai, and H. Wang, J. Nanoparticle Research 11, 1 (2009).
4. V. L. Colvin, Nat. Biotechnol. 21, 10 (2003).
5. M. P. Holsapple, W H. Farland, T. D. Landry, N. A. Monteiro-Riviere, J. M. Carter, N. J. Walker, and K. V. Thomas, Toxicol. Sci. 88, 1 (2005).
6. K. Thomas and P. Sayre, Toxicol. Sci. 87, 2 (2005).
7. G. Oberdorster, E. Oberdorster, and J. Oberdorster, Environ. Health Perspect. 113, 7 (2005).
8. G. Oberdorster, A. Maynard, K. Donaldson, V. Castranova, J. Fitzpatrick, K. Ausman, J. Carter, B. Karn, W. Kreyling, D. Lai, S. Olin, N. Monteiro-Riviere, D. Warheit, and H. Yang, Part. Fibre. Toxicol. 2 (2005).
9. S. S. Lee, H. J. Kim, T. M. Chung, Y. K. Lee, C. G. Kim, and K. S. An, J. Nanosci. Nanotechnol. 8, 9 (2008).
10. D. S. Lee, J. Luo, Y. Fu, W I. Milne, N. M. Park, S. H. Kim, M. y Jung, and S. Maeng, J. Nanosci. Nanotechnol. 8, 9 (2008).
11. A. Skoczynska, D. Kwiecinska, M. Kielbinski, and M. Lukaszewski, Hum. Exp. Toxicol. 26, 8 (2007).
12. N. Leone, D. Courbon, P. Ducimetiere, and M. Zureik, Epidemiology 17, 3 (2006).
13. P. Blanc, H. Wong, M. S. Bernstein, and H. A. Boushey, Ann. Intern. Med. 114, 11 (1991).
14. J. M. Fine, T. Gordon, L. C. Chen, P. Kinney, G. Falcone, and W. S. Beckett, J. Occup. Environ. Med. 39, 8 (1997).
15. W G. Kuschner, A. D'Alessandro, S. F. Wintermeyer, H. Wong, H. A. Boushey, and P. D. Blanc, J. Investig. Med. 43, 4 (1995).
16. J. L. Malo, A. Cartier, and J. Dolovich, Eur. Respir. J. 6, 3 (1993).
17. J. L. Malo, J. Malo, A. Cartier, and J. Dolovich, Eur. Respir. J. 3, 1 (1990).
18. B. Wang, W. Feng, M. Wang, T. Wang, Y. Gu, M. Zhu, H. Ouyang, J. Shi, F. Zhang, Y. Zhao, Z. Chai, H. Wang, and J. Wang, J. Nanoparticle Research 10, 2 (2008).
19. M. T. Zhu, W. y Feng, B. Wang, T. C. Wang, Y. Q. Gu, M. Wang, Y Wang, H. Ouyang, Y L. Zhao, and Z. F. Chai, Toxicology 247, 2 (2008).
20. J. Kaur, P. Muttil, R. K. Verma, K. Kumar, A. B. Yadav, R. Sharma, and A. Misra, Eur. J. Pharm. Sci. 34, 1 (2008).
21. M. M. Bailey and C. J. Berkland, Med. Res. Rev. 29, 1 (2009).
22. J. C. Sung, B. L. Pulliam, and D. A. Edwards, Trends Biotechnol. 25, 12 (2007).
23. H. Okamoto, M. Aoki, and K. Danjo, J. Pharm. Sci. 89, 8 (2000).
24. W S. Beckett, D. F. Chalupa, A. Pauly-Brown, D. M. Speers, J. C. Stewart, M. W Frampton, M. J. Utell, L. S. Huang, C. Cox, W. Zareba, and G. Oberdorster, Am. J. Respir. Crit. Care Med. 171, 10 (2005).
25. A. Ibald-Mulli, H. E. Wichmann, W. Kreyling, and A. Peters, J. Aerosol. Med. 15, 2 (2002).
26. V. Stone, H. Johnston, and M. J. Clift, IEEE. Trans. Nanobioscience 6, 331 (2007).
27. J. Wang, G. Zhou, C. Chen, H. Yu, T. Wang, Y. Ma, G. Jia, Y. Gao, B. Li, J. Sun, Y. Li, F. Jiao, Y. Zhao, and Z. Chai, Toxicol. Lett. 168, 2 (2007).
28. E. Bermudez, J. B. Mangum, B. Asgharian, B. A. Wong, E. E. Reverdy, D. B. Janszen, P. M. Hext, D. B. Warheit, and J. I. Everitt, Toxicol. Sci. 70, 1 (2002).
29. H. W Chen, S. F. Su, C. T. Chien, W. H. Lin, S. L. Yu, C. C. Chou, J. J. Chen, and P. C. Yang, FASEB J. 20, 13 (2006).
30. A. A. Shvedova, E. R. Kisin, R. Mercer, A. R. Murray, V. J. Johnson, A. I. Potapovich, Y. y Tyurina, O. Gorelik, S. Arepalli, D. Schwegler-Berry, A. F. Hubbs, J. Antonini, D. E. Evans, B. K. Ku, D. Ramsey, A. Maynard, V. E. Kagan, V. Castranova, and P. Baron, Am. J. Physiol. Lung Cell Mol. Physiol. 289, 5 (2005).
31. Z. Chen, H. Meng, G. Xing, C. Chen, Y. Zhao, G. Jia, T. Wang, H. Yuan, C. Ye, F. Zhao, Z. Chai, C. Zhu, X. Fang, B. Ma, and L. Wan, Toxicol. Lett. 163, 2 (2006).
32. B. Wang, W. y Feng, M. Wang, J. W Shi, F. Zhang, H. Ouyang, Y L. Zhao, Z. F. Chai, Y. y Huang, Y N. Xie, H. F. Wang, and J. Wang, Biol. Trace Elem. Res. 118, 3 (2007).
33. J. X. Wang, Y F. Li, G. Q. Zhou, B. Li, F. Jiao, C. y Chen, Y X. Gao, Y L. Zhao, and Z. F. Chai, Chin. J. Prev. Med. 41, 2 (2007).
34. M. T. Zhu, W. y Feng, Y. Wang, B. Wang, M. Wang, H. Ouyang, Y L. Zhao, and Z. F. Chai, Toxicol. Sci. 107, 2 (2009).
35. J. X. Wang, Y. Liu, F. Jiao, F. Lao, W. Li, Y Q. Gu, Y F. Li, C. C. Ge, G. Q. Zhou, B. Li, Y L. Zhao, Z. F. Chai, and C. y Chen, Toxicology 254, 1 (2008).
36. J. X. Wang, C. y Chen, Y. Liu, F. Jiao, W. Li, F. Lao, Y F. Li, B. Li, C. C. Ge, G. Q. Zhou, Y X. Gao, Y L. Zhao, and Z. F. Chai, Toxicol. Lett. 183, 1 (2008).
37. D. D. Morgan, D. Warshawsky, R. W. Niemeier, and E. Bingham, Toxicology 33, 3 (1984).
38. N. M. Franklin, N. J. Rogers, S. C. Apte, G. E. Batley, G. E. Gadd, and P. S. Casey, Environ. Sci. Technol. 41, 24 (2007).
39. T. Xia, M. Kovochich, M. Liong, L. Madler, B. Gilbert, H. Shi, J. I. Yeh, J. I. Zink, and A. E. Nel, ACS Nano 2, 10 (2008).
40. M. Frenet, F. Vincent, and H. L. Boiteau, Toxicol. Eur. Res. 5, 3 (1983).
41. T. C. Wang, Y. Liu, G. Jia, X. Wang, C. y Chen, and Y L. Zhao, Chin. J. Prev. Med. 41, 2 (2007).
42. Z. H. Liu, X. Wang, L. Yan, T. C. Wang, R. J. Pei, T. Yan, X. y Zhang, and G. Jia, Chin. J. Prev. Med. 41, 643 (2007).